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The map label for this gene is 148260204

Identifier: 148260204

GI number: 148260204

Start: 1336217

End: 1337146

Strand: Reverse

Name: 148260204

Synonym: Acry_1200

Alternate gene names: NA

Gene position: 1337146-1336217 (Counterclockwise)

Preceding gene: 148260205

Following gene: 148260203

Centisome position: 39.45

GC content: 69.68

Gene sequence:

>930_bases
ATGCCCGTTGCCCTGATCACCCATCCCGCCTGCTTCGACCACGATACCGGCCCGCACCACCCCGAGCGCCCGGCGCGGCT
GCGGGCCGTGCTGGGCGCGCTGGAAACGCCCGAATTCCAGCATCTGCTGCGCGAGGTGGCGCCGGAGGCGCCTGAATCCG
CGCTGCGCGCGGTGCATCACGACGCTTATGTCGATTCGATCCTGGCGATGGCGCCGGCGGAAGGCGAACCGGTGCATCTC
GATGCCGACACGCTGATGAGCCATGGCAGCCTCGCCGCGGCGCTGCGCTCGGCCGGCGGCGCCATGCGCGCGGTCGACGC
GGTGATGGAGGGCTGGGCCCGCGCCGCCTTCGTTGCCACGCGGCCGCCGGGGCATCACGCCGAGCCGAATCGTGCCATGG
GCTTCTGCCTGTTCGCCAATGCCGCGATCGCCGCGCATCATGCCCGCGCCCATGGTCTGAAGCGCGTTGCCGTGGTCGAT
TTCGATGTCCATCACGGCAACGGCACCCAGGCGATGTTCGAGACGGATGCCGACCTGTTCTATGCCTCCTCGCACCAGTA
TCCGTGCTATCCGGGCACCGGCCGCCCTTCCGAGCGCGGGGTTGCCGGCAATATCGTCAACGCCGCGCTGCCGCCCGGCT
CGGGCTCGGCCGAGTTCCGCACCGCTTGGCAGGACACGCTGATCCCCGCACTCGAGCGGTTCGCGCCGGAACTGCTCATC
ATCTCCGCCGGGTTCGATGCCCACCGGTTCGATCCGCTCGCCGAACTCAATGTCGAAACCGCCGATTTCGCCTGGCTGAC
CGAGGCGCTTGTGCGCGTCGCCGACCGGCATTGCGGCGGCAAGGTGGTTTCCCTGCTCGAGGGCGGCTACGATCTCGAGG
CGCTCGCCGCTGGCACCGCCGCCCATGTCCGCGCCTTGATGCGGCATTGA

Upstream 100 bases:

>100_bases
ACCATCCGCGCCGGCGGCGCGAAACAGGAGGCCGCCGCGAAGGAAGCGGCCCGGCACGACGCCGCCAGATAAGCAAACCA
ACAGGGAGACTCCGAGACAG

Downstream 100 bases:

>100_bases
TCCGGCGCTATCGCGGGGAAAACTTGGGAGTTTCGATCATGGCCGCAGCCAAGCCGGACGCCGGCGCCCCGGAGTCGGGA
CCGGACATCGACAAGTTGTC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MPVALITHPACFDHDTGPHHPERPARLRAVLGALETPEFQHLLREVAPEAPESALRAVHHDAYVDSILAMAPAEGEPVHL
DADTLMSHGSLAAALRSAGGAMRAVDAVMEGWARAAFVATRPPGHHAEPNRAMGFCLFANAAIAAHHARAHGLKRVAVVD
FDVHHGNGTQAMFETDADLFYASSHQYPCYPGTGRPSERGVAGNIVNAALPPGSGSAEFRTAWQDTLIPALERFAPELLI
ISAGFDAHRFDPLAELNVETADFAWLTEALVRVADRHCGGKVVSLLEGGYDLEALAAGTAAHVRALMRH

Sequences:

>Translated_309_residues
MPVALITHPACFDHDTGPHHPERPARLRAVLGALETPEFQHLLREVAPEAPESALRAVHHDAYVDSILAMAPAEGEPVHL
DADTLMSHGSLAAALRSAGGAMRAVDAVMEGWARAAFVATRPPGHHAEPNRAMGFCLFANAAIAAHHARAHGLKRVAVVD
FDVHHGNGTQAMFETDADLFYASSHQYPCYPGTGRPSERGVAGNIVNAALPPGSGSAEFRTAWQDTLIPALERFAPELLI
ISAGFDAHRFDPLAELNVETADFAWLTEALVRVADRHCGGKVVSLLEGGYDLEALAAGTAAHVRALMRH
>Mature_308_residues
PVALITHPACFDHDTGPHHPERPARLRAVLGALETPEFQHLLREVAPEAPESALRAVHHDAYVDSILAMAPAEGEPVHLD
ADTLMSHGSLAAALRSAGGAMRAVDAVMEGWARAAFVATRPPGHHAEPNRAMGFCLFANAAIAAHHARAHGLKRVAVVDF
DVHHGNGTQAMFETDADLFYASSHQYPCYPGTGRPSERGVAGNIVNAALPPGSGSAEFRTAWQDTLIPALERFAPELLII
SAGFDAHRFDPLAELNVETADFAWLTEALVRVADRHCGGKVVSLLEGGYDLEALAAGTAAHVRALMRH

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=304, Percent_Identity=36.5131578947368, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI20070354, Length=303, Percent_Identity=37.6237623762376, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI153085395, Length=256, Percent_Identity=37.5, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI17158039, Length=248, Percent_Identity=37.9032258064516, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI30795204, Length=248, Percent_Identity=37.9032258064516, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI30795202, Length=248, Percent_Identity=37.9032258064516, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI62750349, Length=257, Percent_Identity=36.1867704280156, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI62750347, Length=257, Percent_Identity=36.1867704280156, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI148539870, Length=255, Percent_Identity=35.6862745098039, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI169234807, Length=255, Percent_Identity=35.6862745098039, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI226529806, Length=303, Percent_Identity=34.3234323432343, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI8923769, Length=248, Percent_Identity=24.5967741935484, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI217272877, Length=251, Percent_Identity=25.4980079681275, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI13128860, Length=276, Percent_Identity=23.5507246376812, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=315, Percent_Identity=33.3333333333333, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17540332, Length=309, Percent_Identity=33.6569579288026, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193206283, Length=309, Percent_Identity=33.6569579288026, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193209491, Length=339, Percent_Identity=32.7433628318584, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17537347, Length=324, Percent_Identity=34.5679012345679, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25154020, Length=298, Percent_Identity=31.5436241610738, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25154022, Length=299, Percent_Identity=31.1036789297659, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17508561, Length=267, Percent_Identity=25.8426966292135, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534739, Length=301, Percent_Identity=24.2524916943522, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561978, Length=178, Percent_Identity=30.3370786516854, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324307, Length=325, Percent_Identity=32.3076923076923, Blast_Score=149, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6325141, Length=290, Percent_Identity=29.6551724137931, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325325, Length=169, Percent_Identity=28.9940828402367, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323999, Length=265, Percent_Identity=25.6603773584906, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI281360899, Length=312, Percent_Identity=32.3717948717949, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24642142, Length=312, Percent_Identity=32.3717948717949, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24642144, Length=312, Percent_Identity=32.3717948717949, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24642146, Length=312, Percent_Identity=32.3717948717949, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI281360799, Length=332, Percent_Identity=35.2409638554217, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24641720, Length=337, Percent_Identity=35.0148367952522, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281360801, Length=332, Percent_Identity=35.2409638554217, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24657891, Length=266, Percent_Identity=24.812030075188, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32966; Mature: 32835

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVALITHPACFDHDTGPHHPERPARLRAVLGALETPEFQHLLREVAPEAPESALRAVHH
CCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHH
DAYVDSILAMAPAEGEPVHLDADTLMSHGSLAAALRSAGGAMRAVDAVMEGWARAAFVAT
HHHHHHHHHHCCCCCCCEEECHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEE
RPPGHHAEPNRAMGFCLFANAAIAAHHARAHGLKRVAVVDFDVHHGNGTQAMFETDADLF
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCCEEEECCCCEE
YASSHQYPCYPGTGRPSERGVAGNIVNAALPPGSGSAEFRTAWQDTLIPALERFAPELLI
EECCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEE
ISAGFDAHRFDPLAELNVETADFAWLTEALVRVADRHCGGKVVSLLEGGYDLEALAAGTA
EECCCCCHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHCCHH
AHVRALMRH
HHHHHHHCC
>Mature Secondary Structure 
PVALITHPACFDHDTGPHHPERPARLRAVLGALETPEFQHLLREVAPEAPESALRAVHH
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHH
DAYVDSILAMAPAEGEPVHLDADTLMSHGSLAAALRSAGGAMRAVDAVMEGWARAAFVAT
HHHHHHHHHHCCCCCCCEEECHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEE
RPPGHHAEPNRAMGFCLFANAAIAAHHARAHGLKRVAVVDFDVHHGNGTQAMFETDADLF
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCCEEEECCCCEE
YASSHQYPCYPGTGRPSERGVAGNIVNAALPPGSGSAEFRTAWQDTLIPALERFAPELLI
EECCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEE
ISAGFDAHRFDPLAELNVETADFAWLTEALVRVADRHCGGKVVSLLEGGYDLEALAAGTA
EECCCCCHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHCCHH
AHVRALMRH
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]