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The map label for this gene is yxlA [H]

Identifier: 148260153

GI number: 148260153

Start: 1280041

End: 1281429

Strand: Reverse

Name: yxlA [H]

Synonym: Acry_1149

Alternate gene names: 148260153

Gene position: 1281429-1280041 (Counterclockwise)

Preceding gene: 148260154

Following gene: 148260152

Centisome position: 37.81

GC content: 63.21

Gene sequence:

>1389_bases
ATGACAAACCAGGCCCAGAAAGCGGGCGATACGAAATCGGGCTTCTCGGTCGAATCCAAGGGCATCGCCCAGGTCACTCC
GGAGGAAGCCTATGGCAAGCCCTCGCATCTCTTCGGACTCTGGATGGCGGTGAACGTCGAATTCGCCACCATCACCACCG
GGGCGATCGCAACCGGCGTATTCGGCCTCTCGGTGCCCGACGCGGTCGTGGCGATCGTCGGCGCCAACATTCTGGGTTGC
CTGCTGCTCGGCCTCTTCTCGACCTATGGCGTCGATTACGGCCTGCCGATGATGATCCTGTGCGAACGCTGGTTCGGGCG
GTTCGGCAACCGGGTCCTTTCGTTCCTCAACTTTCTCAACGGCTTTTCATGGTTCGCGATCAACACCGTGATCGGCGCCT
ATTTCGTCCATCGCGTGCTCGGCGCCAGCCTGGTCGTCGGCATCGTCGGCCTCACGATCATCCAGGTGCTGATCGCGATC
GTCGGGCATGACTTCATCATCAAGGCGGAAAAGGTCTTCTTCTGGTTCCTTGGCGCCGTCTTCGCGATCCTGACGGCGCT
GACCCTCGCCCATATCCCGCATCTGCCGGTCGCCGATCCGAAGAAGCTCGCGGAAGTGGGAGGTCGTTCCGGCGCGATCC
TGCTCACCGTCTCGATCATGCTCTCCTGGCTGGGCGGCTGGATCCTGTATTCGGGCGACTATTCGCGCTACATGTGCTAC
CGGCACAACCGCGAGGCGATCAAGCGCGGCGTCTTCTGGAACGCCTTCCTCGGCTGCTTCATCTCGTCGACCTGGCTCGA
GGTGGTCGGAGCGGTCATCGGCGGCACCGTCGCGCTGAACAGCCCGGCCGACCTGTTCTCGTCCTGGCTGCCCGGCTGGT
TCCGCGTTCCGCTGATCGTCGCCATCGTCATCGGCACGATCAGCCCGAACGTGCTGAACATATATTCCGCCAGCCTCTCC
GCCCTGGCTTCGGGAATCCGCATGAAGCAATGGCAGGCGGCCCTGCTGACGGGCGGCGTCGGACTGATCATCTCGCTGCT
CGCCTACCAGCATTTCTACAAGAACTACGAACTCCTGCTCTTCTTCCTCGGCTACGTGATCTTCCCGCGCTTCCCGGTGA
TGGCGATCGGCCATCTCCGCCCGCGCGTCTCGCGCTTCGCGTCGATCGACGTGACGACGGTCGGCTTCCTCTCCTGGCTC
GCCGGTGTCGTCTGCAGCGTGCCGTTCTGGAACCAGTATCCGGTCTTCGTCGGCGCCTTCGCGGCCGTTCATCCGGAATT
CGGCGACATTTCCTTCTTCATCGGCGCGTTCGTCGCCGCGATCGTCTATCTCCTCGCCACCATCCCGCGCACGGCGCCGA
TCCCGGCGGGTGCTGTGCCCAGCGCGTAA

Upstream 100 bases:

>100_bases
CTTCCGCCTCGCCCGTCGCGTCGCCGCGCCGGCCGACTCCGCGACCGCCTTTTCAGAGTAATAGAAACCGGACCCAAACC
GGAACCCACAGGAGGACGTC

Downstream 100 bases:

>100_bases
GGACGCCGCATGATGATCCCGCCCAGCCCCGGCCGTCTCGCCATCCGCGCTCAGTTGCTCGGCTACGACGGCAATCCCTT
CGTGTCGGATCCCGCGGACT

Product: cytosine/purines, uracil, thiamine, allantoin permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTNQAQKAGDTKSGFSVESKGIAQVTPEEAYGKPSHLFGLWMAVNVEFATITTGAIATGVFGLSVPDAVVAIVGANILGC
LLLGLFSTYGVDYGLPMMILCERWFGRFGNRVLSFLNFLNGFSWFAINTVIGAYFVHRVLGASLVVGIVGLTIIQVLIAI
VGHDFIIKAEKVFFWFLGAVFAILTALTLAHIPHLPVADPKKLAEVGGRSGAILLTVSIMLSWLGGWILYSGDYSRYMCY
RHNREAIKRGVFWNAFLGCFISSTWLEVVGAVIGGTVALNSPADLFSSWLPGWFRVPLIVAIVIGTISPNVLNIYSASLS
ALASGIRMKQWQAALLTGGVGLIISLLAYQHFYKNYELLLFFLGYVIFPRFPVMAIGHLRPRVSRFASIDVTTVGFLSWL
AGVVCSVPFWNQYPVFVGAFAAVHPEFGDISFFIGAFVAAIVYLLATIPRTAPIPAGAVPSA

Sequences:

>Translated_462_residues
MTNQAQKAGDTKSGFSVESKGIAQVTPEEAYGKPSHLFGLWMAVNVEFATITTGAIATGVFGLSVPDAVVAIVGANILGC
LLLGLFSTYGVDYGLPMMILCERWFGRFGNRVLSFLNFLNGFSWFAINTVIGAYFVHRVLGASLVVGIVGLTIIQVLIAI
VGHDFIIKAEKVFFWFLGAVFAILTALTLAHIPHLPVADPKKLAEVGGRSGAILLTVSIMLSWLGGWILYSGDYSRYMCY
RHNREAIKRGVFWNAFLGCFISSTWLEVVGAVIGGTVALNSPADLFSSWLPGWFRVPLIVAIVIGTISPNVLNIYSASLS
ALASGIRMKQWQAALLTGGVGLIISLLAYQHFYKNYELLLFFLGYVIFPRFPVMAIGHLRPRVSRFASIDVTTVGFLSWL
AGVVCSVPFWNQYPVFVGAFAAVHPEFGDISFFIGAFVAAIVYLLATIPRTAPIPAGAVPSA
>Mature_461_residues
TNQAQKAGDTKSGFSVESKGIAQVTPEEAYGKPSHLFGLWMAVNVEFATITTGAIATGVFGLSVPDAVVAIVGANILGCL
LLGLFSTYGVDYGLPMMILCERWFGRFGNRVLSFLNFLNGFSWFAINTVIGAYFVHRVLGASLVVGIVGLTIIQVLIAIV
GHDFIIKAEKVFFWFLGAVFAILTALTLAHIPHLPVADPKKLAEVGGRSGAILLTVSIMLSWLGGWILYSGDYSRYMCYR
HNREAIKRGVFWNAFLGCFISSTWLEVVGAVIGGTVALNSPADLFSSWLPGWFRVPLIVAIVIGTISPNVLNIYSASLSA
LASGIRMKQWQAALLTGGVGLIISLLAYQHFYKNYELLLFFLGYVIFPRFPVMAIGHLRPRVSRFASIDVTTVGFLSWLA
GVVCSVPFWNQYPVFVGAFAAVHPEFGDISFFIGAFVAAIVYLLATIPRTAPIPAGAVPSA

Specific function: Unknown

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320897, Length=336, Percent_Identity=28.2738095238095, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320902, Length=338, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320903, Length=336, Percent_Identity=27.0833333333333, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 49941; Mature: 49810

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQAQKAGDTKSGFSVESKGIAQVTPEEAYGKPSHLFGLWMAVNVEFATITTGAIATGV
CCCCCHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHEEEEEEEEEHHHHHHHH
FGLSVPDAVVAIVGANILGCLLLGLFSTYGVDYGLPMMILCERWFGRFGNRVLSFLNFLN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GFSWFAINTVIGAYFVHRVLGASLVVGIVGLTIIQVLIAIVGHDFIIKAEKVFFWFLGAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHH
FAILTALTLAHIPHLPVADPKKLAEVGGRSGAILLTVSIMLSWLGGWILYSGDYSRYMCY
HHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHH
RHNREAIKRGVFWNAFLGCFISSTWLEVVGAVIGGTVALNSPADLFSSWLPGWFRVPLIV
HCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHCCHHHHHHHHH
AIVIGTISPNVLNIYSASLSALASGIRMKQWQAALLTGGVGLIISLLAYQHFYKNYELLL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHH
FFLGYVIFPRFPVMAIGHLRPRVSRFASIDVTTVGFLSWLAGVVCSVPFWNQYPVFVGAF
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AAVHPEFGDISFFIGAFVAAIVYLLATIPRTAPIPAGAVPSA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TNQAQKAGDTKSGFSVESKGIAQVTPEEAYGKPSHLFGLWMAVNVEFATITTGAIATGV
CCCCHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHEEEEEEEEEHHHHHHHH
FGLSVPDAVVAIVGANILGCLLLGLFSTYGVDYGLPMMILCERWFGRFGNRVLSFLNFLN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GFSWFAINTVIGAYFVHRVLGASLVVGIVGLTIIQVLIAIVGHDFIIKAEKVFFWFLGAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHH
FAILTALTLAHIPHLPVADPKKLAEVGGRSGAILLTVSIMLSWLGGWILYSGDYSRYMCY
HHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHH
RHNREAIKRGVFWNAFLGCFISSTWLEVVGAVIGGTVALNSPADLFSSWLPGWFRVPLIV
HCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHCCHHHHHHHHH
AIVIGTISPNVLNIYSASLSALASGIRMKQWQAALLTGGVGLIISLLAYQHFYKNYELLL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHH
FFLGYVIFPRFPVMAIGHLRPRVSRFASIDVTTVGFLSWLAGVVCSVPFWNQYPVFVGAF
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AAVHPEFGDISFFIGAFVAAIVYLLATIPRTAPIPAGAVPSA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]