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The map label for this gene is etfA [H]

Identifier: 148260007

GI number: 148260007

Start: 1105307

End: 1106383

Strand: Reverse

Name: etfA [H]

Synonym: Acry_0998

Alternate gene names: 148260007

Gene position: 1106383-1105307 (Counterclockwise)

Preceding gene: 148260008

Following gene: 148260006

Centisome position: 32.64

GC content: 77.16

Gene sequence:

>1077_bases
GTGAGCGCGAAGCGGCGCGATCCCCGGGCCGAGCGCGCGGCGGTGGTGGTGGCCGAGGCGCCGCGCCGGCGGATCGACCG
GACGCATCGCGGCGGGGCGGTCGCGCAGGGCGCCACGGTGGCGCCGGCGGCGGCGCCGGTCGTGACGATCGCGGACCCGG
CCTATCTGGTGTTCGCCGTGGTGGAGATGGCGGGCGGCGTGCTGTCGCGCCATGACCGGCAGGTGCTGGGGGCGGCGCGG
CTGCTCGATGGCGGCGGGACGGCGGCGGTGGTGCTGCTGGCGCCGGGCCTGCCGGAGGACGCCGGTGCGGCGGGGGCGGA
CCGGGTGATGGTGCTGGCGGAGCGGGACGATCCGGCGGCGCTGGCGGCATCGGTCGCCGCCGCGATCCGGGCGCATGGGC
CGCGCCATGTGGTGTTCGCCGAGAGCGCGGATGGCGGGGATCTGGCGCGGCGGGTGGCGGCACTCTGCGACGAGGCGCTG
TTCGATGCGGTCGAGAGCCTGTCGGCGCGGCAGGCGATCCGCCCGGCTGCCGCGGGGCGGGCGGAATGGCGGGCGGCGCC
GCCGCGTCTGCTGAGCATCGCGGCCGACCGCATCGCGCCCTGGCGCGGGGCGGCGCATGCGGCCGAGCCGGTCGATCCGC
CGGCCGATCCGGCGAGGGATGCGGCGCTGGCGGTGCGGCTGTCGCCGCTGCCGGTGGAGGCGGCGAATGTGCGGCTGGAC
GAGGCGGGATTCGTGATCGCGGCGGGGAACGGGGTGACGGATTTCGCGGGGTTTCTCGATCTCGCGCGCGCGCTCGGGGC
GACGCCGGGGGGGAGCCGGGTGGTGTGCGACGCCGGCGCGTTGCCGCGGGCGATGCAGGTCGGCGCGTCGGGCACCGTGC
TCAACGCCGACTGCTACGTGGCGTTCGGGATTTCCGGCGCGCCGCAGCATCTGCAGGGGATCGGCACGGTGGAGCATGTG
GTCGCGGTGAATACCGACCTGCACGCGGCGATGATCGCGCGGGCGGACCTGGCGGTGGTCGCGGATGCGCAGGCGGTGCT
GCCGGCGCTGCTCGCGCTTCTGGGAGCCGAGGCATGA

Upstream 100 bases:

>100_bases
CCGCGATGCTGGAGGGGGTGACAGGCGCGCGGCCCGAGGTGCGCGACATTGCCGAGCTGGTGCACGCGGCGATGGCCACG
GTGCCGGCGGAGGCGCGGGC

Downstream 100 bases:

>100_bases
GAATCGTCGTGCTGCTGTCCGCCGGGCGGCATCCGGCGACGGGCGCGCCCTGCCCGGTGCCGGCGGAATTGCAGGCGATC
GCGCTGGCGCGGCAGATCGC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSAKRRDPRAERAAVVVAEAPRRRIDRTHRGGAVAQGATVAPAAAPVVTIADPAYLVFAVVEMAGGVLSRHDRQVLGAAR
LLDGGGTAAVVLLAPGLPEDAGAAGADRVMVLAERDDPAALAASVAAAIRAHGPRHVVFAESADGGDLARRVAALCDEAL
FDAVESLSARQAIRPAAAGRAEWRAAPPRLLSIAADRIAPWRGAAHAAEPVDPPADPARDAALAVRLSPLPVEAANVRLD
EAGFVIAAGNGVTDFAGFLDLARALGATPGGSRVVCDAGALPRAMQVGASGTVLNADCYVAFGISGAPQHLQGIGTVEHV
VAVNTDLHAAMIARADLAVVADAQAVLPALLALLGAEA

Sequences:

>Translated_358_residues
MSAKRRDPRAERAAVVVAEAPRRRIDRTHRGGAVAQGATVAPAAAPVVTIADPAYLVFAVVEMAGGVLSRHDRQVLGAAR
LLDGGGTAAVVLLAPGLPEDAGAAGADRVMVLAERDDPAALAASVAAAIRAHGPRHVVFAESADGGDLARRVAALCDEAL
FDAVESLSARQAIRPAAAGRAEWRAAPPRLLSIAADRIAPWRGAAHAAEPVDPPADPARDAALAVRLSPLPVEAANVRLD
EAGFVIAAGNGVTDFAGFLDLARALGATPGGSRVVCDAGALPRAMQVGASGTVLNADCYVAFGISGAPQHLQGIGTVEHV
VAVNTDLHAAMIARADLAVVADAQAVLPALLALLGAEA
>Mature_357_residues
SAKRRDPRAERAAVVVAEAPRRRIDRTHRGGAVAQGATVAPAAAPVVTIADPAYLVFAVVEMAGGVLSRHDRQVLGAARL
LDGGGTAAVVLLAPGLPEDAGAAGADRVMVLAERDDPAALAASVAAAIRAHGPRHVVFAESADGGDLARRVAALCDEALF
DAVESLSARQAIRPAAAGRAEWRAAPPRLLSIAADRIAPWRGAAHAAEPVDPPADPARDAALAVRLSPLPVEAANVRLDE
AGFVIAAGNGVTDFAGFLDLARALGATPGGSRVVCDAGALPRAMQVGASGTVLNADCYVAFGISGAPQHLQGIGTVEHVV
AVNTDLHAAMIARADLAVVADAQAVLPALLALLGAEA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=255, Percent_Identity=29.8039215686275, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4503607, Length=255, Percent_Identity=29.8039215686275, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1787990, Length=125, Percent_Identity=34.4, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786226, Length=271, Percent_Identity=28.0442804428044, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=261, Percent_Identity=32.5670498084291, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325261, Length=248, Percent_Identity=27.0161290322581, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17136898, Length=228, Percent_Identity=29.3859649122807, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24652801, Length=228, Percent_Identity=29.3859649122807, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 36101; Mature: 35970

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKRRDPRAERAAVVVAEAPRRRIDRTHRGGAVAQGATVAPAAAPVVTIADPAYLVFAV
CCCCCCCCCCHHEEEEEECCCHHHHHHCCCCCCCCCCCEECCCCCCEEEECCHHHHHHHH
VEMAGGVLSRHDRQVLGAARLLDGGGTAAVVLLAPGLPEDAGAAGADRVMVLAERDDPAA
HHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCHHH
LAASVAAAIRAHGPRHVVFAESADGGDLARRVAALCDEALFDAVESLSARQAIRPAAAGR
HHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCC
AEWRAAPPRLLSIAADRIAPWRGAAHAAEPVDPPADPARDAALAVRLSPLPVEAANVRLD
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHCEEEE
EAGFVIAAGNGVTDFAGFLDLARALGATPGGSRVVCDAGALPRAMQVGASGTVLNADCYV
CCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCCEEECCEEE
AFGISGAPQHLQGIGTVEHVVAVNTDLHAAMIARADLAVVADAQAVLPALLALLGAEA
EECCCCCHHHHHHCCHHHHEEEECCCHHHHHHHHCCHHEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAKRRDPRAERAAVVVAEAPRRRIDRTHRGGAVAQGATVAPAAAPVVTIADPAYLVFAV
CCCCCCCCCHHEEEEEECCCHHHHHHCCCCCCCCCCCEECCCCCCEEEECCHHHHHHHH
VEMAGGVLSRHDRQVLGAARLLDGGGTAAVVLLAPGLPEDAGAAGADRVMVLAERDDPAA
HHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCHHH
LAASVAAAIRAHGPRHVVFAESADGGDLARRVAALCDEALFDAVESLSARQAIRPAAAGR
HHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCC
AEWRAAPPRLLSIAADRIAPWRGAAHAAEPVDPPADPARDAALAVRLSPLPVEAANVRLD
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHCEEEE
EAGFVIAAGNGVTDFAGFLDLARALGATPGGSRVVCDAGALPRAMQVGASGTVLNADCYV
CCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCCEEECCEEE
AFGISGAPQHLQGIGTVEHVVAVNTDLHAAMIARADLAVVADAQAVLPALLALLGAEA
EECCCCCHHHHHHCCHHHHEEEECCCHHHHHHHHCCHHEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]