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The map label for this gene is zraS [C]

Identifier: 148259776

GI number: 148259776

Start: 854832

End: 856538

Strand: Reverse

Name: zraS [C]

Synonym: Acry_0764

Alternate gene names: 148259776

Gene position: 856538-854832 (Counterclockwise)

Preceding gene: 148259777

Following gene: 148259771

Centisome position: 25.27

GC content: 67.72

Gene sequence:

>1707_bases
GTGGCTGAGACTTCGATCCCGCTGACGCTGGCGCAGGCCGGTGCGACCGATCCGGCGCCCGAAGCGTTCATGCCCGCCAT
GATCGCCGGTTTTGACTGGGCCGCGACACCGCTCGGCCCGATCGATACCTGGTCGGCAATCCGGCGGCGGACCGTGCAGC
TGATCTGCCGCTCGGACATCGCCATCGCGACAATGTGGGGCCCCGAGGGCATCCTGATCTACAACGACGCCTGCGCCGCG
CTGCTTGGCCGGCATCATCCGGGCAGCCTCGGGCAGCCGGCGGCGCAGGCGAACCCGCGCATGAAGCGCTTCATCCGCGA
CATTCTCGCCCGTGTCCACGCGGGCGAGACGGTGGTGCTGCACGATTACAGCCTGGTGTCCGACCGTGGCGACAGCCCCG
AGCAGATCTGGCTCAGCCTGTCCTATACGCCGATTCTCGACGCCGACGGCCGGATCGACGGGGTGCACGCCGCCCTGACG
GAAACGACGAACCAGGTGCGCGAGCGCGAGGAGGTCGAGACCGCGTTGCGGCAGTCGATGAAAATGGAGGCGATCGGCCA
GCTGACGGGCGGCATTTCGCACGACTTCAACAATCTTCTCACCGGGATTCTTGGCAATCTCGACATGCTGGCGACGCGGA
TCGAGCAGGGCGACCACGCGTCCGCGATGTCCTATCTCGATGGCGCGCGCAGCGCCGCGAGCCGGGCCGCCGGCCTGACC
CAGCGGCTGCTGACCTTCGCGCGCCGGCAAGCCCTGGCGCCCGCCGCCATCTCGGTGGCGACGCTGCTCGACGACCTGCA
CGAACTGATCGACCGGACCGTGGGGCCGGCCATCGAGGTGCAAACGCTCTACCCGCCGGATCTCCGCGCCGGCTTCTGCG
ATCGCAACCAGCTGGAGAACGCGCTGCTGAACCTCGCCATCAACGCACGCGACGCGATGCCGGAAGGCGGCAGGCTCACG
ATCGAGGCGAGCAATGCCACGCTGGTAGCACCCGCCCGCGGCCAGACGCACACGGAAGGCGACTATGTCCGGCTGACCAT
CACGGATACCGGCTGCGGCATGTCGGACGAGGTCAAGGACCGCGTCTTCGAACCGTTCTTCACCACCAAGCCCGCAGGCC
AGGGCACCGGGCTCGGCCTGTCGATGGTGTATGGTTTCATCAAGCAGTCGGGCGGGCACATCGAACTTGCCAGCGAGGCC
GGCAGGGGCACGAAGATCAGCCTGTTCATTCCCTGCAACCAGCTTTCCGGCGCCACAGAAACATCAGACGCTCCGGCGCC
GGCGCCCGACATGCGATGGGACGAAACCTCCGGCCTCATCCTCGTCGTCGATGATGAGCCGGGCCTGCGCACGCTGCTCG
CCGACATGCTCCGCGAACAGGGATTTTCCGTGCGGATGGCCGCGGACGCGGAAGCCGCCCTCGCGATCCTTCGCGCGGAG
CCGGATATCGATCTGCTGATCGCCGATATCGGGCTGCCCGGCGCCATGAATGGACGGCAACTGGCCCTTGCCGCGCGCGC
CGACCGCCCCGAACTGCCCCTTCTTTTCGTGACCGGGCTGGACGAAACCACATCGTCCGGACCGCCGTTCGACAGCGCGC
CCACCGCGATGCTGCGAAAGCCCTTCTCGTTCGGCTGCCTTCACACGCAGGTCGGCCTGTTGCTGGCCCATAGCCGGACG
GCGACACCGCCCCGAAGCATGGGCTGA

Upstream 100 bases:

>100_bases
ACGGAACGGGGCAAAAAAGCGGCGGTGGGCGACCTCGCCACGGCAATGATGTGACCGCGCGGGACGCCGGTTCCCGGCCG
CGGGCTGGAGACAACCGACG

Downstream 100 bases:

>100_bases
CCGGACGCTCCTCGGGAAATCGTCGATCCGGCGGTTTCAGCCGGCGAGCGCGCGCAGGGCCCTTGCCTGATCCGGCCAGT
TCGGCAGGCCGCCAGCATGT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MAETSIPLTLAQAGATDPAPEAFMPAMIAGFDWAATPLGPIDTWSAIRRRTVQLICRSDIAIATMWGPEGILIYNDACAA
LLGRHHPGSLGQPAAQANPRMKRFIRDILARVHAGETVVLHDYSLVSDRGDSPEQIWLSLSYTPILDADGRIDGVHAALT
ETTNQVREREEVETALRQSMKMEAIGQLTGGISHDFNNLLTGILGNLDMLATRIEQGDHASAMSYLDGARSAASRAAGLT
QRLLTFARRQALAPAAISVATLLDDLHELIDRTVGPAIEVQTLYPPDLRAGFCDRNQLENALLNLAINARDAMPEGGRLT
IEASNATLVAPARGQTHTEGDYVRLTITDTGCGMSDEVKDRVFEPFFTTKPAGQGTGLGLSMVYGFIKQSGGHIELASEA
GRGTKISLFIPCNQLSGATETSDAPAPAPDMRWDETSGLILVVDDEPGLRTLLADMLREQGFSVRMAADAEAALAILRAE
PDIDLLIADIGLPGAMNGRQLALAARADRPELPLLFVTGLDETTSSGPPFDSAPTAMLRKPFSFGCLHTQVGLLLAHSRT
ATPPRSMG

Sequences:

>Translated_568_residues
MAETSIPLTLAQAGATDPAPEAFMPAMIAGFDWAATPLGPIDTWSAIRRRTVQLICRSDIAIATMWGPEGILIYNDACAA
LLGRHHPGSLGQPAAQANPRMKRFIRDILARVHAGETVVLHDYSLVSDRGDSPEQIWLSLSYTPILDADGRIDGVHAALT
ETTNQVREREEVETALRQSMKMEAIGQLTGGISHDFNNLLTGILGNLDMLATRIEQGDHASAMSYLDGARSAASRAAGLT
QRLLTFARRQALAPAAISVATLLDDLHELIDRTVGPAIEVQTLYPPDLRAGFCDRNQLENALLNLAINARDAMPEGGRLT
IEASNATLVAPARGQTHTEGDYVRLTITDTGCGMSDEVKDRVFEPFFTTKPAGQGTGLGLSMVYGFIKQSGGHIELASEA
GRGTKISLFIPCNQLSGATETSDAPAPAPDMRWDETSGLILVVDDEPGLRTLLADMLREQGFSVRMAADAEAALAILRAE
PDIDLLIADIGLPGAMNGRQLALAARADRPELPLLFVTGLDETTSSGPPFDSAPTAMLRKPFSFGCLHTQVGLLLAHSRT
ATPPRSMG
>Mature_567_residues
AETSIPLTLAQAGATDPAPEAFMPAMIAGFDWAATPLGPIDTWSAIRRRTVQLICRSDIAIATMWGPEGILIYNDACAAL
LGRHHPGSLGQPAAQANPRMKRFIRDILARVHAGETVVLHDYSLVSDRGDSPEQIWLSLSYTPILDADGRIDGVHAALTE
TTNQVREREEVETALRQSMKMEAIGQLTGGISHDFNNLLTGILGNLDMLATRIEQGDHASAMSYLDGARSAASRAAGLTQ
RLLTFARRQALAPAAISVATLLDDLHELIDRTVGPAIEVQTLYPPDLRAGFCDRNQLENALLNLAINARDAMPEGGRLTI
EASNATLVAPARGQTHTEGDYVRLTITDTGCGMSDEVKDRVFEPFFTTKPAGQGTGLGLSMVYGFIKQSGGHIELASEAG
RGTKISLFIPCNQLSGATETSDAPAPAPDMRWDETSGLILVVDDEPGLRTLLADMLREQGFSVRMAADAEAALAILRAEP
DIDLLIADIGLPGAMNGRQLALAARADRPELPLLFVTGLDETTSSGPPFDSAPTAMLRKPFSFGCLHTQVGLLLAHSRTA
TPPRSMG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=28.8537549407115, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788549, Length=344, Percent_Identity=27.3255813953488, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=431, Percent_Identity=25.754060324826, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI48994928, Length=464, Percent_Identity=23.7068965517241, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790300, Length=249, Percent_Identity=26.1044176706827, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=24.1228070175439, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60683; Mature: 60552

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETSIPLTLAQAGATDPAPEAFMPAMIAGFDWAATPLGPIDTWSAIRRRTVQLICRSDI
CCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCE
AIATMWGPEGILIYNDACAALLGRHHPGSLGQPAAQANPRMKRFIRDILARVHAGETVVL
EEEEEECCCEEEEECCHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEE
HDYSLVSDRGDSPEQIWLSLSYTPILDADGRIDGVHAALTETTNQVREREEVETALRQSM
ECCHHHCCCCCCCCEEEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KMEAIGQLTGGISHDFNNLLTGILGNLDMLATRIEQGDHASAMSYLDGARSAASRAAGLT
HHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
QRLLTFARRQALAPAAISVATLLDDLHELIDRTVGPAIEVQTLYPPDLRAGFCDRNQLEN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHH
ALLNLAINARDAMPEGGRLTIEASNATLVAPARGQTHTEGDYVRLTITDTGCGMSDEVKD
HHHHEEEECCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCEEEEEEEECCCCCCHHHHH
RVFEPFFTTKPAGQGTGLGLSMVYGFIKQSGGHIELASEAGRGTKISLFIPCNQLSGATE
HHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCC
TSDAPAPAPDMRWDETSGLILVVDDEPGLRTLLADMLREQGFSVRMAADAEAALAILRAE
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHEEEEECC
PDIDLLIADIGLPGAMNGRQLALAARADRPELPLLFVTGLDETTSSGPPFDSAPTAMLRK
CCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCC
PFSFGCLHTQVGLLLAHSRTATPPRSMG
CCCCCHHHHHHHHHEECCCCCCCCCCCC
>Mature Secondary Structure 
AETSIPLTLAQAGATDPAPEAFMPAMIAGFDWAATPLGPIDTWSAIRRRTVQLICRSDI
CCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCE
AIATMWGPEGILIYNDACAALLGRHHPGSLGQPAAQANPRMKRFIRDILARVHAGETVVL
EEEEEECCCEEEEECCHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEE
HDYSLVSDRGDSPEQIWLSLSYTPILDADGRIDGVHAALTETTNQVREREEVETALRQSM
ECCHHHCCCCCCCCEEEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KMEAIGQLTGGISHDFNNLLTGILGNLDMLATRIEQGDHASAMSYLDGARSAASRAAGLT
HHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
QRLLTFARRQALAPAAISVATLLDDLHELIDRTVGPAIEVQTLYPPDLRAGFCDRNQLEN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHH
ALLNLAINARDAMPEGGRLTIEASNATLVAPARGQTHTEGDYVRLTITDTGCGMSDEVKD
HHHHEEEECCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCEEEEEEEECCCCCCHHHHH
RVFEPFFTTKPAGQGTGLGLSMVYGFIKQSGGHIELASEAGRGTKISLFIPCNQLSGATE
HHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCC
TSDAPAPAPDMRWDETSGLILVVDDEPGLRTLLADMLREQGFSVRMAADAEAALAILRAE
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHEEEEECC
PDIDLLIADIGLPGAMNGRQLALAARADRPELPLLFVTGLDETTSSGPPFDSAPTAMLRK
CCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCC
PFSFGCLHTQVGLLLAHSRTATPPRSMG
CCCCCHHHHHHHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA