Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 148259736

GI number: 148259736

Start: 808362

End: 809210

Strand: Reverse

Name: uppP

Synonym: Acry_0723

Alternate gene names: 148259736

Gene position: 809210-808362 (Counterclockwise)

Preceding gene: 148259738

Following gene: 148259735

Centisome position: 23.88

GC content: 70.79

Gene sequence:

>849_bases
ATGACCCCGCTGATCGCCGTCCTCTTCGCCATCCTGCAAGGGGCGACCGAGTTGTTCCCCGTCTCCAGCCTCGGCCATGT
GGTGATCGTCCCCGCCCTGCTGCACTGGCCCATCGACCAGGCCTCGCCCTCGTTCCTGCCCTTCGTCGTCATGCTCCATG
TCGGCACCGCGACGGCGCTGCTGCTCTATTTCTGGCGCGAATGGTGGGCGATGCTCGCCGGCCTGCTCGGCCGCGGCGAA
CCCGGCGAGGTCGATGCCCAGCGCGGCCTGCTGCTGCGCCTCGTCGTCGCCACCCTGCCGGCCGTGCTCATCGGCTTCGC
GCTGAAAAAGCCGATCCAGCATCTCTTCGCCAGCCCCGAGATTGCCGCCGCCTTCCTCATCGCCAACGGCGCGGTGCTGA
TCATCGGCGAACGGCTGCGCCGCCGCCGCGCCGGCAACGGCTTCGGCATCGGCCAGCTTACCCTCCGCGACTCGCTGGTG
ATCGGCCTGTTCCAGTGCCTCGCCTTCCTGCCCGGCCTGTCGCGCTCGGGCTCGGCGATCGTCGGCGGCCTGACCCGCGG
CCTCGACCACGAGGCCGCCGCCCGCTTCGCCTTCCTGATGGCCACCCCGGTGATCGCCGGCGCCGCGGTGATCGAGGTGC
CGCATCTCCTGCATCACGCCGCCGCCGCGCGCGGCATGTTCGGCACCGCCCTGCTCGCCGCCGTCGTCGCCGGCGTCGTC
GCCTATCTCTCGACCGCGTTCCTGATGCGCTATTTCCGCAATCACGACCGCTGGGCGCTCGGCCCCTTCGCCGCCTATTG
CGCCCTGTTCGGCGCGCTGAGCCTGATCCTGATCCCGTTCGGCGCCTGA

Upstream 100 bases:

>100_bases
TCATTATCCTGTCGCCGTCCGGCGGGGCCGCGCCGCGATGCGTTGCCTTCGCCGCGCTTGTTTGCCAAGTGAAGCGGCAC
CCACAACCGCCGGAGCCGCC

Downstream 100 bases:

>100_bases
TGGCAACCGCGCGCCCCGACATCGTCCGGCTGATGGGCGCGCGCGGGGCGCGCAGCATCGCCCAGGGCGCGCTGGTGGTC
GATTTCGCGCTCTACGTCAC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTPLIAVLFAILQGATELFPVSSLGHVVIVPALLHWPIDQASPSFLPFVVMLHVGTATALLLYFWREWWAMLAGLLGRGE
PGEVDAQRGLLLRLVVATLPAVLIGFALKKPIQHLFASPEIAAAFLIANGAVLIIGERLRRRRAGNGFGIGQLTLRDSLV
IGLFQCLAFLPGLSRSGSAIVGGLTRGLDHEAAARFAFLMATPVIAGAAVIEVPHLLHHAAAARGMFGTALLAAVVAGVV
AYLSTAFLMRYFRNHDRWALGPFAAYCALFGALSLILIPFGA

Sequences:

>Translated_282_residues
MTPLIAVLFAILQGATELFPVSSLGHVVIVPALLHWPIDQASPSFLPFVVMLHVGTATALLLYFWREWWAMLAGLLGRGE
PGEVDAQRGLLLRLVVATLPAVLIGFALKKPIQHLFASPEIAAAFLIANGAVLIIGERLRRRRAGNGFGIGQLTLRDSLV
IGLFQCLAFLPGLSRSGSAIVGGLTRGLDHEAAARFAFLMATPVIAGAAVIEVPHLLHHAAAARGMFGTALLAAVVAGVV
AYLSTAFLMRYFRNHDRWALGPFAAYCALFGALSLILIPFGA
>Mature_281_residues
TPLIAVLFAILQGATELFPVSSLGHVVIVPALLHWPIDQASPSFLPFVVMLHVGTATALLLYFWREWWAMLAGLLGRGEP
GEVDAQRGLLLRLVVATLPAVLIGFALKKPIQHLFASPEIAAAFLIANGAVLIIGERLRRRRAGNGFGIGQLTLRDSLVI
GLFQCLAFLPGLSRSGSAIVGGLTRGLDHEAAARFAFLMATPVIAGAAVIEVPHLLHHAAAARGMFGTALLAAVVAGVVA
YLSTAFLMRYFRNHDRWALGPFAAYCALFGALSLILIPFGA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=265, Percent_Identity=31.3207547169811, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_ACICJ (A5FWG2)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001233863.1
- STRING:   A5FWG2
- GeneID:   5161175
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_0723
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   DEPPERA
- ProtClustDB:   PRK00281
- BioCyc:   ACRY349163:ACRY_0723-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29973; Mature: 29842

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13414238)-; HASH(0x13a12288)-; HASH(0x13e4c69c)-; HASH(0x13a2b800)-; HASH(0x13e43608)-; HASH(0x13c9358c)-; HASH(0x13df3900)-; HASH(0x13abeb64)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLIAVLFAILQGATELFPVSSLGHVVIVPALLHWPIDQASPSFLPFVVMLHVGTATAL
CCHHHHHHHHHHHCHHHHCCHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LLYFWREWWAMLAGLLGRGEPGEVDAQRGLLLRLVVATLPAVLIGFALKKPIQHLFASPE
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
IAAAFLIANGAVLIIGERLRRRRAGNGFGIGQLTLRDSLVIGLFQCLAFLPGLSRSGSAI
HHHHHHHHCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
VGGLTRGLDHEAAARFAFLMATPVIAGAAVIEVPHLLHHAAAARGMFGTALLAAVVAGVV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLSTAFLMRYFRNHDRWALGPFAAYCALFGALSLILIPFGA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
TPLIAVLFAILQGATELFPVSSLGHVVIVPALLHWPIDQASPSFLPFVVMLHVGTATAL
CHHHHHHHHHHHCHHHHCCHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LLYFWREWWAMLAGLLGRGEPGEVDAQRGLLLRLVVATLPAVLIGFALKKPIQHLFASPE
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
IAAAFLIANGAVLIIGERLRRRRAGNGFGIGQLTLRDSLVIGLFQCLAFLPGLSRSGSAI
HHHHHHHHCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
VGGLTRGLDHEAAARFAFLMATPVIAGAAVIEVPHLLHHAAAARGMFGTALLAAVVAGVV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLSTAFLMRYFRNHDRWALGPFAAYCALFGALSLILIPFGA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA