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The map label for this gene is acuC [H]

Identifier: 148259710

GI number: 148259710

Start: 780752

End: 781825

Strand: Reverse

Name: acuC [H]

Synonym: Acry_0697

Alternate gene names: 148259710

Gene position: 781825-780752 (Counterclockwise)

Preceding gene: 148259713

Following gene: 148259709

Centisome position: 23.07

GC content: 74.39

Gene sequence:

>1074_bases
GTGCTGATCGGGGCGGAGGTGTATCGGGCGGCGATCGCGGCGCCGCCGCATCCGCTGGCGACGATGAGGGCGCCGGTGGC
GGAGGATCTGATCCGGGCGATGGGGTGGCTGGCGGCGGGGCAGTATCGGACGGCGCCGGTGGCGGGGCGCGCGGCGCTGG
AGCGGTTTCACGATCCGGCCTATCTCGACGCGCTGGAGGCGGCGGAGCGGACGCAGGAGGTGCCGGCGGAGGCGCGGGCG
CGGTTCGGCATCGGGGCGGAGGGGAATCCGATGCATCGCGCGGTGTATCGGCGGCCGGCGACCTCGGCGGGGGGCGCGAT
GCTGGCGGCACGGCTGACGGCGGAGGGCGGGGTCGCGCATGTGCCGGCGGCGGGGAACCATCATGCCTGGCCGGCGCGGG
CGAGCGGGTTCTGCTATATCAATGATGCGGTGCTGGCGCTGATGGAGTGGCTCGACCTCGGGCTGGAGCGGCTGGTCTAT
CTCGATCTCGACGCGCATCACGGCGATGGGGTGGAGGCGGCGTTCGCGCGCGATGGGCGGGTGACGACGATCAGCGTGCA
TGAGGCGGGGCGGTGGCCGCGGACGGGGGGGACGAGCGACGCGGCGGCGGGGGTGTTCAATTTTGCCGTGCCGGAGGGGT
TTTGCGACGCGGAGCTGGCGTTCCTGATGGAGGCGCGGATCGTGCCGGCGATCGCGGCGGCGCGGCCGGAGGGGATCGTG
TTCCTGCCGGGGGCGGATGCGCTGGCGGATGATCCGATGAGCCGGCTGGCGCTGTCGAACCGGGGGTTGTGGGCGGCGCT
GGAGGCGATCCGCGGGCTAGCGCCGCGGCTGATCGTGCTCGGGGGTGGCGGGTATAACCCGTATGCGCTCGGGCGGGCCT
GGGCGGGGTTGTGGGGCGTGCTGAACGGGCACGCGGTGCCGGAGGCGCTGCCGCCGGCGGCCTTGGACGTGCTGGCGGGA
ATCAGCTATTTCCGCGGGCAGTCGCGGCCGAGGCCGGCGCACTGGCTCACCCGCCTCGACGATCCGCCGCAGGCGGGCCT
GGTGCGGGACGAGGTGCGCCGCCTCGCCGCGTGA

Upstream 100 bases:

>100_bases
CGTCCTGCGCGAGCGTTGTCAATTCGTCACTCATGCCCAGCCTATAGCAACGGCGGGGCTTGATGGGTAGGCAAGGCGGA
TGAGCGGGACGCGCAAGGCG

Downstream 100 bases:

>100_bases
CGCAACAAGGAGCAGGACGATGAGACGCTGGATGGGAATTTGCCTTGCGGCCGGGATTGCTGGCGGATCGGCCGTCGGGG
TGGCCGCGGCGGCGATCACC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLIGAEVYRAAIAAPPHPLATMRAPVAEDLIRAMGWLAAGQYRTAPVAGRAALERFHDPAYLDALEAAERTQEVPAEARA
RFGIGAEGNPMHRAVYRRPATSAGGAMLAARLTAEGGVAHVPAAGNHHAWPARASGFCYINDAVLALMEWLDLGLERLVY
LDLDAHHGDGVEAAFARDGRVTTISVHEAGRWPRTGGTSDAAAGVFNFAVPEGFCDAELAFLMEARIVPAIAAARPEGIV
FLPGADALADDPMSRLALSNRGLWAALEAIRGLAPRLIVLGGGGYNPYALGRAWAGLWGVLNGHAVPEALPPAALDVLAG
ISYFRGQSRPRPAHWLTRLDDPPQAGLVRDEVRRLAA

Sequences:

>Translated_357_residues
MLIGAEVYRAAIAAPPHPLATMRAPVAEDLIRAMGWLAAGQYRTAPVAGRAALERFHDPAYLDALEAAERTQEVPAEARA
RFGIGAEGNPMHRAVYRRPATSAGGAMLAARLTAEGGVAHVPAAGNHHAWPARASGFCYINDAVLALMEWLDLGLERLVY
LDLDAHHGDGVEAAFARDGRVTTISVHEAGRWPRTGGTSDAAAGVFNFAVPEGFCDAELAFLMEARIVPAIAAARPEGIV
FLPGADALADDPMSRLALSNRGLWAALEAIRGLAPRLIVLGGGGYNPYALGRAWAGLWGVLNGHAVPEALPPAALDVLAG
ISYFRGQSRPRPAHWLTRLDDPPQAGLVRDEVRRLAA
>Mature_357_residues
MLIGAEVYRAAIAAPPHPLATMRAPVAEDLIRAMGWLAAGQYRTAPVAGRAALERFHDPAYLDALEAAERTQEVPAEARA
RFGIGAEGNPMHRAVYRRPATSAGGAMLAARLTAEGGVAHVPAAGNHHAWPARASGFCYINDAVLALMEWLDLGLERLVY
LDLDAHHGDGVEAAFARDGRVTTISVHEAGRWPRTGGTSDAAAGVFNFAVPEGFCDAELAFLMEARIVPAIAAARPEGIV
FLPGADALADDPMSRLALSNRGLWAALEAIRGLAPRLIVLGGGGYNPYALGRAWAGLWGVLNGHAVPEALPPAALDVLAG
ISYFRGQSRPRPAHWLTRLDDPPQAGLVRDEVRRLAA

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI8923769, Length=298, Percent_Identity=32.2147651006711, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI13128860, Length=310, Percent_Identity=29.3548387096774, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI13128862, Length=305, Percent_Identity=29.8360655737705, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI262073088, Length=211, Percent_Identity=34.5971563981043, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI293336691, Length=310, Percent_Identity=30.6451612903226, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI262073092, Length=217, Percent_Identity=32.7188940092166, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI209862883, Length=207, Percent_Identity=29.951690821256, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI217272877, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI13128864, Length=306, Percent_Identity=27.1241830065359, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508561, Length=309, Percent_Identity=32.0388349514563, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17534739, Length=310, Percent_Identity=31.9354838709677, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17561978, Length=289, Percent_Identity=31.4878892733564, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17540334, Length=361, Percent_Identity=26.0387811634349, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17540332, Length=361, Percent_Identity=25.4847645429363, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI193206283, Length=361, Percent_Identity=24.9307479224377, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17537347, Length=262, Percent_Identity=24.8091603053435, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323999, Length=304, Percent_Identity=32.8947368421053, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321244, Length=306, Percent_Identity=28.7581699346405, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6325325, Length=184, Percent_Identity=40.7608695652174, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6324307, Length=273, Percent_Identity=26.7399267399267, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24657891, Length=289, Percent_Identity=29.757785467128, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24644244, Length=311, Percent_Identity=29.5819935691318, Blast_Score=121, Evalue=6e-28,
Organism=Drosophila melanogaster, GI281360899, Length=240, Percent_Identity=30.4166666666667, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642146, Length=240, Percent_Identity=30.4166666666667, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642142, Length=240, Percent_Identity=30.4166666666667, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642144, Length=240, Percent_Identity=30.4166666666667, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649807, Length=282, Percent_Identity=25.886524822695, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 37774; Mature: 37774

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIGAEVYRAAIAAPPHPLATMRAPVAEDLIRAMGWLAAGQYRTAPVAGRAALERFHDPA
CCCCHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHH
YLDALEAAERTQEVPAEARARFGIGAEGNPMHRAVYRRPATSAGGAMLAARLTAEGGVAH
HHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCEEE
VPAAGNHHAWPARASGFCYINDAVLALMEWLDLGLERLVYLDLDAHHGDGVEAAFARDGR
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEECCCC
VTTISVHEAGRWPRTGGTSDAAAGVFNFAVPEGFCDAELAFLMEARIVPAIAAARPEGIV
EEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
FLPGADALADDPMSRLALSNRGLWAALEAIRGLAPRLIVLGGGGYNPYALGRAWAGLWGV
EECCCCHHHCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LNGHAVPEALPPAALDVLAGISYFRGQSRPRPAHWLTRLDDPPQAGLVRDEVRRLAA
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLIGAEVYRAAIAAPPHPLATMRAPVAEDLIRAMGWLAAGQYRTAPVAGRAALERFHDPA
CCCCHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHH
YLDALEAAERTQEVPAEARARFGIGAEGNPMHRAVYRRPATSAGGAMLAARLTAEGGVAH
HHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCEEE
VPAAGNHHAWPARASGFCYINDAVLALMEWLDLGLERLVYLDLDAHHGDGVEAAFARDGR
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEECCCC
VTTISVHEAGRWPRTGGTSDAAAGVFNFAVPEGFCDAELAFLMEARIVPAIAAARPEGIV
EEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
FLPGADALADDPMSRLALSNRGLWAALEAIRGLAPRLIVLGGGGYNPYALGRAWAGLWGV
EECCCCHHHCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LNGHAVPEALPPAALDVLAGISYFRGQSRPRPAHWLTRLDDPPQAGLVRDEVRRLAA
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]