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The map label for this gene is lspA [H]

Identifier: 148259646

GI number: 148259646

Start: 713198

End: 713731

Strand: Reverse

Name: lspA [H]

Synonym: Acry_0632

Alternate gene names: 148259646

Gene position: 713731-713198 (Counterclockwise)

Preceding gene: 148259647

Following gene: 148259645

Centisome position: 21.06

GC content: 69.29

Gene sequence:

>534_bases
ATGACCGGCGCATCTCGCGGTAACGCAAGCCGCCGCACGCTCGGCGCGCTGATGGCGCTGGCGGTGCTGGCCATCGACCA
GGCCTCGAAGGCCTGGATCCTCTACGGACTCGACCTGCCGCGGAAGGGCAGCGTGCCGGTCCTGCCGGTGCTGAACTTCA
CCATGGTCTGGAACCACGGCGTCACCTTCGGCATCCTGGCCGGCGACGACGCGCGGCTGCTGCTGATCGCGGTCGCGATC
GCCGCCATCGCCGGGCTCTCGGTCTGGCTCTGGCGCACCCCCTCGCTGCTCGCGGCGCTCGGCCTCGGCGCCATCATCGG
CGGCGCCGCCGGCAACGTCATCTCGCGAATCGCCTACGGCGCGGTGGTCGATTTCGTCGATGTCCATGTCGGCAACCTGC
ATTGGTACGTCTTCAACCTCGCCGACGCAGCGATCGATGGCGGCGTCGCCGCGCTGATCATCGAAAGCCTGTTCAGCCGC
GACCGCGCCGGTCACTTGCCGCCTCCCGCGCGCGAGGATAAGGAAGCGCCATGA

Upstream 100 bases:

>100_bases
CCCCCGGGGAGAAATGCGAGCGCTGCTGGAAGGTGCTGCCCGAGGTCGGCGGCAACCCCGCGCATCCCGGCCTGTGCCGC
CGCTGCTGCACGTATGTCGA

Downstream 100 bases:

>100_bases
TCCGTTCATCGCGCGCGACCCTTCCGTTCCTGCTGCTCGGCCCGCTGCTGCTGGCCGGATGCAGCAATCCGTCGAAGACC
TTCGGGCTGACGGTCACGCC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MTGASRGNASRRTLGALMALAVLAIDQASKAWILYGLDLPRKGSVPVLPVLNFTMVWNHGVTFGILAGDDARLLLIAVAI
AAIAGLSVWLWRTPSLLAALGLGAIIGGAAGNVISRIAYGAVVDFVDVHVGNLHWYVFNLADAAIDGGVAALIIESLFSR
DRAGHLPPPAREDKEAP

Sequences:

>Translated_177_residues
MTGASRGNASRRTLGALMALAVLAIDQASKAWILYGLDLPRKGSVPVLPVLNFTMVWNHGVTFGILAGDDARLLLIAVAI
AAIAGLSVWLWRTPSLLAALGLGAIIGGAAGNVISRIAYGAVVDFVDVHVGNLHWYVFNLADAAIDGGVAALIIESLFSR
DRAGHLPPPAREDKEAP
>Mature_176_residues
TGASRGNASRRTLGALMALAVLAIDQASKAWILYGLDLPRKGSVPVLPVLNFTMVWNHGVTFGILAGDDARLLLIAVAIA
AIAGLSVWLWRTPSLLAALGLGAIIGGAAGNVISRIAYGAVVDFVDVHVGNLHWYVFNLADAAIDGGVAALIIESLFSRD
RAGHLPPPAREDKEAP

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=160, Percent_Identity=35.625, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18470; Mature: 18339

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGASRGNASRRTLGALMALAVLAIDQASKAWILYGLDLPRKGSVPVLPVLNFTMVWNHG
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEHHHHEEEEECCC
VTFGILAGDDARLLLIAVAIAAIAGLSVWLWRTPSLLAALGLGAIIGGAAGNVISRIAYG
CEEEEEECCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
AVVDFVDVHVGNLHWYVFNLADAAIDGGVAALIIESLFSRDRAGHLPPPAREDKEAP
HHHHHHHHEECCEEEEEEEHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGASRGNASRRTLGALMALAVLAIDQASKAWILYGLDLPRKGSVPVLPVLNFTMVWNHG
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEHHHHEEEEECCC
VTFGILAGDDARLLLIAVAIAAIAGLSVWLWRTPSLLAALGLGAIIGGAAGNVISRIAYG
CEEEEEECCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
AVVDFVDVHVGNLHWYVFNLADAAIDGGVAALIIESLFSRDRAGHLPPPAREDKEAP
HHHHHHHHEECCEEEEEEEHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA