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The map label for this gene is ctrA [H]

Identifier: 148259590

GI number: 148259590

Start: 646486

End: 647238

Strand: Reverse

Name: ctrA [H]

Synonym: Acry_0574

Alternate gene names: 148259590

Gene position: 647238-646486 (Counterclockwise)

Preceding gene: 148259591

Following gene: 148259588

Centisome position: 19.1

GC content: 58.17

Gene sequence:

>753_bases
ATGCGGCTTCTCATTTTTGGTAAAACGTTCGACAGGCACGACAGCCTGAACAGCTTCATCAAGTCGAAACTCGCCGTCAT
CGACGAGACGGCAGACGTCGACGAAGCGGTCGATCTCTCCCATCATTACGAATATGAAGCGGTGGTGATGCGGGTCTTCG
ATACCTACAGGATCGAGTTCGACCTGATCCGCCGCCTGCGGAAATCCGGATTTCGCGCCCCGATCGTGGCGGTCGCCAAC
ACGCTGGCCGAGTCCGCCCGCCTGCATATTCTTGAGGCCGGGGTCGACGATCTCATCGTTGGCGCTCCCTCATACGAGGA
AACGTTCCTGCGCATCCAGAATCATATACGCAGGAACCGGGGCTTCCAGGACTCTTCGCTTTCCGTTGGCAATATCGAGG
TCAACATGAATGCGAAGAAGGTCTTTGTCGGCGCCCGCGAAGTCGCCGTCACGAAGAAGGAGTATCAGATCATCGAACTC
CTCGCGCTGCGCAAGGGCTGCGTTCTGAGCAAGGAAGCGATCCTCGATCATCTGTACGGCGGCCTCGACGAACCGAACGC
CAAGATCATCGACGTGTTCATCTGCAAGATCCGCAAGAAGCTGCTTGCCGCAGACGGCCAGGACGTGCTCGTCACCAACT
GGGGACGCGGCTATATGATGGCCGACCAGCGCCCCCAGAACATGGTTCAGACGGTGACCGCGCCGGGCATCCAAGCCAGG
ATCAAGACGACTGCAAGCCTTGCAGTCGCTTGA

Upstream 100 bases:

>100_bases
TATTTCAACTTTTTTGAAAAATTTCTCGAAAATTAAAAAATTTTCATTGACCCGTCATTTTTCGGGTTGTATAAACTGAT
TAGATCAACTGGAGGTTGAT

Downstream 100 bases:

>100_bases
CCCTCGAACCCGGGATCTCGCGGCACCTCACTGACCGAAGGCAGCAACGGATGCGGCGATTGGCGCGACCGGCCTGCCCT
GGCTTCGGTGACCGGCATTT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: Response regulator SokA [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MRLLIFGKTFDRHDSLNSFIKSKLAVIDETADVDEAVDLSHHYEYEAVVMRVFDTYRIEFDLIRRLRKSGFRAPIVAVAN
TLAESARLHILEAGVDDLIVGAPSYEETFLRIQNHIRRNRGFQDSSLSVGNIEVNMNAKKVFVGAREVAVTKKEYQIIEL
LALRKGCVLSKEAILDHLYGGLDEPNAKIIDVFICKIRKKLLAADGQDVLVTNWGRGYMMADQRPQNMVQTVTAPGIQAR
IKTTASLAVA

Sequences:

>Translated_250_residues
MRLLIFGKTFDRHDSLNSFIKSKLAVIDETADVDEAVDLSHHYEYEAVVMRVFDTYRIEFDLIRRLRKSGFRAPIVAVAN
TLAESARLHILEAGVDDLIVGAPSYEETFLRIQNHIRRNRGFQDSSLSVGNIEVNMNAKKVFVGAREVAVTKKEYQIIEL
LALRKGCVLSKEAILDHLYGGLDEPNAKIIDVFICKIRKKLLAADGQDVLVTNWGRGYMMADQRPQNMVQTVTAPGIQAR
IKTTASLAVA
>Mature_250_residues
MRLLIFGKTFDRHDSLNSFIKSKLAVIDETADVDEAVDLSHHYEYEAVVMRVFDTYRIEFDLIRRLRKSGFRAPIVAVAN
TLAESARLHILEAGVDDLIVGAPSYEETFLRIQNHIRRNRGFQDSSLSVGNIEVNMNAKKVFVGAREVAVTKKEYQIIEL
LALRKGCVLSKEAILDHLYGGLDEPNAKIIDVFICKIRKKLLAADGQDVLVTNWGRGYMMADQRPQNMVQTVTAPGIQAR
IKTTASLAVA

Specific function: Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle, including cell division, stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787375, Length=160, Percent_Identity=29.375, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790552, Length=179, Percent_Identity=27.3743016759777, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789402, Length=179, Percent_Identity=25.6983240223464, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28062; Mature: 28062

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLIFGKTFDRHDSLNSFIKSKLAVIDETADVDEAVDLSHHYEYEAVVMRVFDTYRIEF
CEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DLIRRLRKSGFRAPIVAVANTLAESARLHILEAGVDDLIVGAPSYEETFLRIQNHIRRNR
HHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHC
GFQDSSLSVGNIEVNMNAKKVFVGAREVAVTKKEYQIIELLALRKGCVLSKEAILDHLYG
CCCCCCEEEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GLDEPNAKIIDVFICKIRKKLLAADGQDVLVTNWGRGYMMADQRPQNMVQTVTAPGIQAR
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCCCCEE
IKTTASLAVA
EEEEEEEECC
>Mature Secondary Structure
MRLLIFGKTFDRHDSLNSFIKSKLAVIDETADVDEAVDLSHHYEYEAVVMRVFDTYRIEF
CEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DLIRRLRKSGFRAPIVAVANTLAESARLHILEAGVDDLIVGAPSYEETFLRIQNHIRRNR
HHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHC
GFQDSSLSVGNIEVNMNAKKVFVGAREVAVTKKEYQIIELLALRKGCVLSKEAILDHLYG
CCCCCCEEEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GLDEPNAKIIDVFICKIRKKLLAADGQDVLVTNWGRGYMMADQRPQNMVQTVTAPGIQAR
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCCCCEE
IKTTASLAVA
EEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8548829 [H]