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The map label for this gene is metX

Identifier: 148259454

GI number: 148259454

Start: 489398

End: 490543

Strand: Reverse

Name: metX

Synonym: Acry_0437

Alternate gene names: 148259454

Gene position: 490543-489398 (Counterclockwise)

Preceding gene: 148259461

Following gene: 148259453

Centisome position: 14.47

GC content: 62.57

Gene sequence:

>1146_bases
ATGGATCAGTCCCCTTTCCCTGACATAGCCCATCAGACGGCATCGTTTTCAGATGGCCTCGTTCTTGACTGCGGCACGAC
GCTGCAGCGGCTCGAGGTGGCCTACCGCACCTATGGCTCGCTGAACGCCGAGAAGAGCAACGCGATCCTCATCTGTCATG
CGCTAACGGGAGACCAGTACGTTGCCGAGCCGCACCCTCTTACGGGAAAGCCGGGCTGGTGGAACGCCCTGGTCGGCGCC
GGCAAGCCGGTCGACACTGATCGGTTCTTCGTGATCTGCGCGAATGTGCTGGGCGGATGCATGGGATCGACGGGACCACG
CAGCCGACGCGATCACGGGGCCGACGAGCCCTGGTCGATCGACTTTCCTGCGATCACCGTTCAGGACATGGTGCGCGCCC
AGAAGAAGCTGGTTGACTGGCTTGGAATCGAACGCCTTTTCGCGGTTGTCGGCGGATCGATGGGGGGCATGCAGGTGCTC
GCCTGGGCTTCGCTGTTTCCGGACCGCGTGTTTGCCGCCGTGCCGATCGCGACCGCGCCTTATCATTCCGCGCAGAACAT
TGCTTTCCATGAGGTCGGCCGGCAAGCGATCTATACCGACCCTGATTTTCATGGTGGCCACTACCGGACACATGGCGTGA
TTCCCGCCCGCGGCCTCGCCGTCGCGCGCATGACCGCACATATCACCTATCTTTCGGAAGCGGCCCTGACCAGGAAATTC
GGCCGCCGGCTACAGCGCCAGAACGCCCTCGCCGCGCCCGTATTCGGTGAACGCTTCGCGGTCGAAAGCTATCTCGAACA
CCAGGGATCGAGCTTCGTGCGGCGATTCGATGCCAACTCGTATCTCGTGATCACGCGGGCAATGGACTATTTCGATCTCG
CCGCCGACCATGGCGGGTCGCTGTCGGCCGCCTTTCGCGGCACGAAGACACGCTTCCTTCTGGTATCCTTCAGTTCCGAC
TGGCTGTTCCCGACAGCGGAAAGCCGGGCTATGGCGCGCGCACTGAATCAGGTCGCGGCGAATGTCAGCTTCGTCGAGAT
CGTCAGTGACAAGGGGCACGATGCTTTCCTGCTCGACGAACCCGACTTCCATCGTACCGTCGCCGGCTTCATCTCCGGCG
CGGCCGAAGCGGCGGGCCTGCAATGA

Upstream 100 bases:

>100_bases
TCCAACATACTGACTTTCAACCTATCTGATACAGGAGGCACGCCGCACGGCAAGCCCCATCCTTGCCGCCCGCATGGGTT
GAGCGCATATCGGGCGGGCC

Downstream 100 bases:

>100_bases
GCCAGCAAGCGCCGGTGCGGTTCGTCGGCAAGAACATGCGCGTCGACCTCGAACTGATCGCAGAGATGATCCCGCCAGGC
TCGCGGGTCCTCGATATCGG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDQSPFPDIAHQTASFSDGLVLDCGTTLQRLEVAYRTYGSLNAEKSNAILICHALTGDQYVAEPHPLTGKPGWWNALVGA
GKPVDTDRFFVICANVLGGCMGSTGPRSRRDHGADEPWSIDFPAITVQDMVRAQKKLVDWLGIERLFAVVGGSMGGMQVL
AWASLFPDRVFAAVPIATAPYHSAQNIAFHEVGRQAIYTDPDFHGGHYRTHGVIPARGLAVARMTAHITYLSEAALTRKF
GRRLQRQNALAAPVFGERFAVESYLEHQGSSFVRRFDANSYLVITRAMDYFDLAADHGGSLSAAFRGTKTRFLLVSFSSD
WLFPTAESRAMARALNQVAANVSFVEIVSDKGHDAFLLDEPDFHRTVAGFISGAAEAAGLQ

Sequences:

>Translated_381_residues
MDQSPFPDIAHQTASFSDGLVLDCGTTLQRLEVAYRTYGSLNAEKSNAILICHALTGDQYVAEPHPLTGKPGWWNALVGA
GKPVDTDRFFVICANVLGGCMGSTGPRSRRDHGADEPWSIDFPAITVQDMVRAQKKLVDWLGIERLFAVVGGSMGGMQVL
AWASLFPDRVFAAVPIATAPYHSAQNIAFHEVGRQAIYTDPDFHGGHYRTHGVIPARGLAVARMTAHITYLSEAALTRKF
GRRLQRQNALAAPVFGERFAVESYLEHQGSSFVRRFDANSYLVITRAMDYFDLAADHGGSLSAAFRGTKTRFLLVSFSSD
WLFPTAESRAMARALNQVAANVSFVEIVSDKGHDAFLLDEPDFHRTVAGFISGAAEAAGLQ
>Mature_381_residues
MDQSPFPDIAHQTASFSDGLVLDCGTTLQRLEVAYRTYGSLNAEKSNAILICHALTGDQYVAEPHPLTGKPGWWNALVGA
GKPVDTDRFFVICANVLGGCMGSTGPRSRRDHGADEPWSIDFPAITVQDMVRAQKKLVDWLGIERLFAVVGGSMGGMQVL
AWASLFPDRVFAAVPIATAPYHSAQNIAFHEVGRQAIYTDPDFHGGHYRTHGVIPARGLAVARMTAHITYLSEAALTRKF
GRRLQRQNALAAPVFGERFAVESYLEHQGSSFVRRFDANSYLVITRAMDYFDLAADHGGSLSAAFRGTKTRFLLVSFSSD
WLFPTAESRAMARALNQVAANVSFVEIVSDKGHDAFLLDEPDFHRTVAGFISGAAEAAGLQ

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=225, Percent_Identity=38.6666666666667, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_ACICJ (A5FVN0)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001233581.1
- ProteinModelPortal:   A5FVN0
- SMR:   A5FVN0
- STRING:   A5FVN0
- GeneID:   5161060
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_0437
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- BioCyc:   ACRY349163:ACRY_0437-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41497; Mature: 41497

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: ACT_SITE 153-153 ACT_SITE 353-353

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQSPFPDIAHQTASFSDGLVLDCGTTLQRLEVAYRTYGSLNAEKSNAILICHALTGDQY
CCCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCE
VAEPHPLTGKPGWWNALVGAGKPVDTDRFFVICANVLGGCMGSTGPRSRRDHGADEPWSI
ECCCCCCCCCCCHHHHHHCCCCCCCCCHHHEEEHHHHHHHCCCCCCCCCCCCCCCCCEEC
DFPAITVQDMVRAQKKLVDWLGIERLFAVVGGSMGGMQVLAWASLFPDRVFAAVPIATAP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHCCCCCCCC
YHSAQNIAFHEVGRQAIYTDPDFHGGHYRTHGVIPARGLAVARMTAHITYLSEAALTRKF
CCCCCCCHHHHHCCEEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRRLQRQNALAAPVFGERFAVESYLEHQGSSFVRRFDANSYLVITRAMDYFDLAADHGGS
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCHHHHHHHCCCCC
LSAAFRGTKTRFLLVSFSSDWLFPTAESRAMARALNQVAANVSFVEIVSDKGHDAFLLDE
EEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECC
PDFHRTVAGFISGAAEAAGLQ
CHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDQSPFPDIAHQTASFSDGLVLDCGTTLQRLEVAYRTYGSLNAEKSNAILICHALTGDQY
CCCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCE
VAEPHPLTGKPGWWNALVGAGKPVDTDRFFVICANVLGGCMGSTGPRSRRDHGADEPWSI
ECCCCCCCCCCCHHHHHHCCCCCCCCCHHHEEEHHHHHHHCCCCCCCCCCCCCCCCCEEC
DFPAITVQDMVRAQKKLVDWLGIERLFAVVGGSMGGMQVLAWASLFPDRVFAAVPIATAP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHCCCCCCCC
YHSAQNIAFHEVGRQAIYTDPDFHGGHYRTHGVIPARGLAVARMTAHITYLSEAALTRKF
CCCCCCCHHHHHCCEEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRRLQRQNALAAPVFGERFAVESYLEHQGSSFVRRFDANSYLVITRAMDYFDLAADHGGS
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCHHHHHHHCCCCC
LSAAFRGTKTRFLLVSFSSDWLFPTAESRAMARALNQVAANVSFVEIVSDKGHDAFLLDE
EEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECC
PDFHRTVAGFISGAAEAAGLQ
CHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA