Click here to switch to the map view.

The map label for this gene is lgt

Identifier: 148259442

GI number: 148259442

Start: 480665

End: 481495

Strand: Reverse

Name: lgt

Synonym: Acry_0425

Alternate gene names: 148259442

Gene position: 481495-480665 (Counterclockwise)

Preceding gene: 148259443

Following gene: 148259441

Centisome position: 14.21

GC content: 62.09

Gene sequence:

>831_bases
ATGAAAAACGTTTATGTCTGGCCGCATTTCGATCCGATTCTTGTCCGGTTCGGACCATTCGCCATCCATTACTATGCGCT
GGCCTATATCACCGCGTTGGTGCTTGGCTGGCGGCTGATGCGCCGCCTCGTGCGCGAGGCGCCGGTCGTCGCAACCCACG
AGCAGGTGGACGATTTCCTGTCCTGGGCAACTCTCGGCGTCGTCCTCGGCGGTCGGCTCGGTTATATTCTGTTCTATCAG
CCGGTCTATTTTCTCGATCATCTGAACCGGACCTATGCCGTGTGGGATGGCGGGATGAGTTTCCACGGCGGCATGCTGGG
TGTGGCGGTCGCAATCCTGATCTATTGCCGCCGGCATGGCATCGACCCGTGGCGTTTCGGCGACCGCGTCGCCGTGCCGG
TGCCGATCGGCCTGTTTCTCGGCCGCATTGCCAATTTCGTGAACGGCGAACTTTGGGGACGCCCCGCGCCAGCCTGGTTT
CCGTTCCGCATGATCTATCCCGAATCCGGGTCGGACGTGCCGCGCTACCCATCCGAACTGATCGAAGCCACGCTCGAGGG
GCTCGTGCTGTTCATCGTTCTGCTCATTGCCTCCCGCAACGAGCGGATCCGCAGCCAGCCCGGCTATCTCGGCGGCATGT
TCGTCATGGGCTACGGCATTGCCCGCACGACCGCCGAATGTTTCCGACAGCCGGACTGGTTTCTCGGCTACCTCATGTTC
GGGCTGACCATGGGACAGTTGCTGTCGATCCCGATGATCGTGATCGGCGCGACGATGATCTGGCGCGCGAAATACGTCGC
TCGCCGCCAGGGCGCCCTCGCCACCGCATGA

Upstream 100 bases:

>100_bases
ACCGCTTGCGCGCGGCCGGCTTCGACCGTCCCTTCACGCCCCTCGAACAGGGCGTCGAGGCCTATATCAGGAACTTCCTC
AGCCGGCCGGATCAGTACCG

Downstream 100 bases:

>100_bases
TCGAGCGGCTTGACGCCTTCATGGCCCGCGCCAATGCCGCTTACTACGCGAGCCGCGATCCGTTTGTGGATTTCGTGACA
GCACCGGAAATCAGCCAGGT

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MKNVYVWPHFDPILVRFGPFAIHYYALAYITALVLGWRLMRRLVREAPVVATHEQVDDFLSWATLGVVLGGRLGYILFYQ
PVYFLDHLNRTYAVWDGGMSFHGGMLGVAVAILIYCRRHGIDPWRFGDRVAVPVPIGLFLGRIANFVNGELWGRPAPAWF
PFRMIYPESGSDVPRYPSELIEATLEGLVLFIVLLIASRNERIRSQPGYLGGMFVMGYGIARTTAECFRQPDWFLGYLMF
GLTMGQLLSIPMIVIGATMIWRAKYVARRQGALATA

Sequences:

>Translated_276_residues
MKNVYVWPHFDPILVRFGPFAIHYYALAYITALVLGWRLMRRLVREAPVVATHEQVDDFLSWATLGVVLGGRLGYILFYQ
PVYFLDHLNRTYAVWDGGMSFHGGMLGVAVAILIYCRRHGIDPWRFGDRVAVPVPIGLFLGRIANFVNGELWGRPAPAWF
PFRMIYPESGSDVPRYPSELIEATLEGLVLFIVLLIASRNERIRSQPGYLGGMFVMGYGIARTTAECFRQPDWFLGYLMF
GLTMGQLLSIPMIVIGATMIWRAKYVARRQGALATA
>Mature_276_residues
MKNVYVWPHFDPILVRFGPFAIHYYALAYITALVLGWRLMRRLVREAPVVATHEQVDDFLSWATLGVVLGGRLGYILFYQ
PVYFLDHLNRTYAVWDGGMSFHGGMLGVAVAILIYCRRHGIDPWRFGDRVAVPVPIGLFLGRIANFVNGELWGRPAPAWF
PFRMIYPESGSDVPRYPSELIEATLEGLVLFIVLLIASRNERIRSQPGYLGGMFVMGYGIARTTAECFRQPDWFLGYLMF
GLTMGQLLSIPMIVIGATMIWRAKYVARRQGALATA

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=275, Percent_Identity=40.7272727272727, Blast_Score=188, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_ACICJ (A5FVL8)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001233569.1
- STRING:   A5FVL8
- GeneID:   5160147
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_0425
- eggNOG:   COG0682
- HOGENOM:   HBG450278
- OMA:   RIGPLAI
- BioCyc:   ACRY349163:ACRY_0425-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 31258; Mature: 31258

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x130495f8)-; HASH(0x130fece4)-; HASH(0x13414220)-; HASH(0x404e1754)-; HASH(0x12e324ac)-; HASH(0x10dbc2c0)-; HASH(0x12ff1390)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVYVWPHFDPILVRFGPFAIHYYALAYITALVLGWRLMRRLVREAPVVATHEQVDDFL
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
SWATLGVVLGGRLGYILFYQPVYFLDHLNRTYAVWDGGMSFHGGMLGVAVAILIYCRRHG
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCC
IDPWRFGDRVAVPVPIGLFLGRIANFVNGELWGRPAPAWFPFRMIYPESGSDVPRYPSEL
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHH
IEATLEGLVLFIVLLIASRNERIRSQPGYLGGMFVMGYGIARTTAECFRQPDWFLGYLMF
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GLTMGQLLSIPMIVIGATMIWRAKYVARRQGALATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MKNVYVWPHFDPILVRFGPFAIHYYALAYITALVLGWRLMRRLVREAPVVATHEQVDDFL
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
SWATLGVVLGGRLGYILFYQPVYFLDHLNRTYAVWDGGMSFHGGMLGVAVAILIYCRRHG
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCC
IDPWRFGDRVAVPVPIGLFLGRIANFVNGELWGRPAPAWFPFRMIYPESGSDVPRYPSEL
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHH
IEATLEGLVLFIVLLIASRNERIRSQPGYLGGMFVMGYGIARTTAECFRQPDWFLGYLMF
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GLTMGQLLSIPMIVIGATMIWRAKYVARRQGALATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA