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The map label for this gene is pheS [H]

Identifier: 148259379

GI number: 148259379

Start: 412542

End: 413666

Strand: Reverse

Name: pheS [H]

Synonym: Acry_0362

Alternate gene names: 148259379

Gene position: 413666-412542 (Counterclockwise)

Preceding gene: 148259385

Following gene: 148259378

Centisome position: 12.21

GC content: 68.53

Gene sequence:

>1125_bases
ATGCGCCGCGTTTGCTTGACATTTCGCCCGCTTCACGCTCCCTGCGCGGCCATGTCCGACGATCTGCCGACCATCGAATC
CCAAGCCCGCACAGCCATCGCCGCCGCCGGCGATCCGGCTGCGCTCGACGCCGTCCGTATCGCCCTGCTCGGCAAGACCG
GGCAGGTCACAGCGCTGCTCAAGACGCTCGGCAGCCTGACGCCGGACGAACGCAAGCGCGTCGGCGCCGAGGTGAACGCG
CTCAAGACCGCCATCTCGGCCGCGCTCGATGCGCGCCGGGCGGTGCTGGAGGCGGAAGCCCTCGCCGCGCGGCTCGCCGC
CGAGCGCATCGACGTCACGCTTCCCGGCCGGCCCGACCGCGCCGGCACGATCCACCCGATCTCGCGCACCATGGAGGAAC
TCACCGCCCTGTTCGGCGCCATGGGCTTCGGCGTGAAGGAAGGACCGGACATCGAGGATGACTGGCACAATTTCGGCGCC
CTCAACATCCCCTCGCACCACCCGGCCCGCGCGATGATGGACACGTTCTATCTCGACGCTGCGGCCGGCAGCCGCCCCGT
CGTGCTGCGCACCCACACCTCGCCGCTGCAGATCCGCACCATGCTGGCCGAGACGCCGCCGATCCGCGTGATCGTGCCGG
GCCGCACCTACCGTTCGGACCACGACGCCACGCACAGCCCGATGTTCCACCAATGCGAGGGGCTGGTGATCGACCGCGGG
ATCACCCTCGCCCATCTCAAGGGCTGCCTGATCGACTTCCTGCGCGCCTTCTTCGAGCGGCCGGACCTCAAGGCCCGCTT
CCGCTCCAGCTATTTCCCCTTCACCGAACCCTCGATGGAGGTCGACATCGCCTGGGACCGCAAGTCCGGCGAGATCGGCG
GCGGCAGCGACTGGCTGGAAATCCTCGGCGCCGGCATGATCCATCCCAACGTGCTGGCGAATTGCGGGCTCGACCCGCGA
GAATTCCAGGGCTTCGCCTTCGGCATGGGGGTCGAGCGCATCACCATGCTCAAGCACGGTATCCCCGACCTCCGTACTTT
CTATGAGAGCGACGTGCGCTGGCTCGCGCATTATGGCACCTCGCCGCTGGCGCCGGTGACCCTGCACGAAGGGGACGCAC
GATGA

Upstream 100 bases:

>100_bases
AAACAGGTTTCAATGCCTTCGGTTCTTTTTTAATCGCGATTTTATCAGTTGCTGAAAACCTCCGGGCCTCGTCCGGAGGT
TTTTTCTTGCCGCCCGCGCC

Downstream 100 bases:

>100_bases
AATTCACCCTCTCCTGGCTCAAGACGCATCTCGACACCGATGCCTCGCTCGATGCCATCGCCGAAACGCTGTCCGCCATC
GGGCTGGAGGTGGAGAGCAT

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRRVCLTFRPLHAPCAAMSDDLPTIESQARTAIAAAGDPAALDAVRIALLGKTGQVTALLKTLGSLTPDERKRVGAEVNA
LKTAISAALDARRAVLEAEALAARLAAERIDVTLPGRPDRAGTIHPISRTMEELTALFGAMGFGVKEGPDIEDDWHNFGA
LNIPSHHPARAMMDTFYLDAAAGSRPVVLRTHTSPLQIRTMLAETPPIRVIVPGRTYRSDHDATHSPMFHQCEGLVIDRG
ITLAHLKGCLIDFLRAFFERPDLKARFRSSYFPFTEPSMEVDIAWDRKSGEIGGGSDWLEILGAGMIHPNVLANCGLDPR
EFQGFAFGMGVERITMLKHGIPDLRTFYESDVRWLAHYGTSPLAPVTLHEGDAR

Sequences:

>Translated_374_residues
MRRVCLTFRPLHAPCAAMSDDLPTIESQARTAIAAAGDPAALDAVRIALLGKTGQVTALLKTLGSLTPDERKRVGAEVNA
LKTAISAALDARRAVLEAEALAARLAAERIDVTLPGRPDRAGTIHPISRTMEELTALFGAMGFGVKEGPDIEDDWHNFGA
LNIPSHHPARAMMDTFYLDAAAGSRPVVLRTHTSPLQIRTMLAETPPIRVIVPGRTYRSDHDATHSPMFHQCEGLVIDRG
ITLAHLKGCLIDFLRAFFERPDLKARFRSSYFPFTEPSMEVDIAWDRKSGEIGGGSDWLEILGAGMIHPNVLANCGLDPR
EFQGFAFGMGVERITMLKHGIPDLRTFYESDVRWLAHYGTSPLAPVTLHEGDAR
>Mature_374_residues
MRRVCLTFRPLHAPCAAMSDDLPTIESQARTAIAAAGDPAALDAVRIALLGKTGQVTALLKTLGSLTPDERKRVGAEVNA
LKTAISAALDARRAVLEAEALAARLAAERIDVTLPGRPDRAGTIHPISRTMEELTALFGAMGFGVKEGPDIEDDWHNFGA
LNIPSHHPARAMMDTFYLDAAAGSRPVVLRTHTSPLQIRTMLAETPPIRVIVPGRTYRSDHDATHSPMFHQCEGLVIDRG
ITLAHLKGCLIDFLRAFFERPDLKARFRSSYFPFTEPSMEVDIAWDRKSGEIGGGSDWLEILGAGMIHPNVLANCGLDPR
EFQGFAFGMGVERITMLKHGIPDLRTFYESDVRWLAHYGTSPLAPVTLHEGDAR

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=272, Percent_Identity=33.4558823529412, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI5729820, Length=268, Percent_Identity=29.4776119402985, Blast_Score=105, Evalue=9e-23,
Organism=Escherichia coli, GI1788007, Length=337, Percent_Identity=54.5994065281899, Blast_Score=382, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI32563657, Length=324, Percent_Identity=28.0864197530864, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17508957, Length=324, Percent_Identity=28.0864197530864, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32566635, Length=253, Percent_Identity=29.2490118577075, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321087, Length=384, Percent_Identity=26.5625, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6325304, Length=116, Percent_Identity=37.0689655172414, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18858079, Length=290, Percent_Identity=28.6206896551724, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI17137424, Length=257, Percent_Identity=26.4591439688716, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 40844; Mature: 40844

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVCLTFRPLHAPCAAMSDDLPTIESQARTAIAAAGDPAALDAVRIALLGKTGQVTALL
CCCEEEEECCCCCCHHHHCCCCCCHHHHHHHEEEECCCCHHHHHHHHEEECCCCHHHHHH
KTLGSLTPDERKRVGAEVNALKTAISAALDARRAVLEAEALAARLAAERIDVTLPGRPDR
HHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
AGTIHPISRTMEELTALFGAMGFGVKEGPDIEDDWHNFGALNIPSHHPARAMMDTFYLDA
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHCC
AAGSRPVVLRTHTSPLQIRTMLAETPPIRVIVPGRTYRSDHDATHSPMFHQCEGLVIDRG
CCCCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCEEEECC
ITLAHLKGCLIDFLRAFFERPDLKARFRSSYFPFTEPSMEVDIAWDRKSGEIGGGSDWLE
CHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHH
ILGAGMIHPNVLANCGLDPREFQGFAFGMGVERITMLKHGIPDLRTFYESDVRWLAHYGT
HHHCCCCCCHHHHHCCCCHHHHCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
SPLAPVTLHEGDAR
CCCCEEEECCCCCC
>Mature Secondary Structure
MRRVCLTFRPLHAPCAAMSDDLPTIESQARTAIAAAGDPAALDAVRIALLGKTGQVTALL
CCCEEEEECCCCCCHHHHCCCCCCHHHHHHHEEEECCCCHHHHHHHHEEECCCCHHHHHH
KTLGSLTPDERKRVGAEVNALKTAISAALDARRAVLEAEALAARLAAERIDVTLPGRPDR
HHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
AGTIHPISRTMEELTALFGAMGFGVKEGPDIEDDWHNFGALNIPSHHPARAMMDTFYLDA
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHCC
AAGSRPVVLRTHTSPLQIRTMLAETPPIRVIVPGRTYRSDHDATHSPMFHQCEGLVIDRG
CCCCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCEEEECC
ITLAHLKGCLIDFLRAFFERPDLKARFRSSYFPFTEPSMEVDIAWDRKSGEIGGGSDWLE
CHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHH
ILGAGMIHPNVLANCGLDPREFQGFAFGMGVERITMLKHGIPDLRTFYESDVRWLAHYGT
HHHCCCCCCHHHHHCCCCHHHHCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
SPLAPVTLHEGDAR
CCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA