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The map label for this gene is fabG2 [H]

Identifier: 148259231

GI number: 148259231

Start: 243647

End: 244348

Strand: Reverse

Name: fabG2 [H]

Synonym: Acry_0211

Alternate gene names: 148259231

Gene position: 244348-243647 (Counterclockwise)

Preceding gene: 148259232

Following gene: 148259222

Centisome position: 7.21

GC content: 72.51

Gene sequence:

>702_bases
ATGGCCAAGGAACGGGTGCTGGTCACGGGCGGGGCTGCGGGCATCGGCGCGGCGAGCGTCGCGCGCTGCCGCGAGGAGGG
CTACGAGGTCGTGGTGATCGACCGGATCGGCGATGGCATCGTCGCCGACCTGTCGGACCCGGCGGCGACCGAGGCCGCCC
TAGCCGAGGCGCTGCGCGGCGGGCCGATCACCCGGCTGGTCAACAATGTCGGCACTGTCCGCCCCGCCCCGGTCGAGGCG
CAGACCGTGGCCGATCTCGACGCCGTGGTCTCGCTCAACCTGCGCTGCAGCCTGCAATGCGTGCAGGCGCTGCTGCCCGG
CATGAAGGCGGCCGGGTTCGGCCGCATCGTCAACATCGCCTCGCGCGCCGCCCTCGGCAAGGAAGACCGCACCGCCTACG
CCGCGACCAAGGCCGGGCTGATCGGCATGGCGAAGGTCTGGGCGCTGGAACTCGGCCGCTTCGGCATCACCGCCAACGCC
ATCGGCCCCGGCCCGATCCGCACCGAGCTGTTCGACCGGGTAAACCCGCCGGACGATCCGCGCACCACGGCGATCATCGA
GGGCATCCCGGTCCGCCGGATCGGCACCCCGGCGGACGTGGCGCACGCAATCGCCTATCTGCTCGACCAGCGCAGCGGCT
TCGTCACCGGCCAGGTGCTCTATGTCTGCGGCGGCATGACCGTCGGCGCCGCCGGGGCCTAA

Upstream 100 bases:

>100_bases
CGCACCCGCGCCGCCCCTTGACGGGGGCGGCGGCATGACGGCTTGAAGAGAGGCCGGCGCCGGATCCACGGCGCCGGCCT
TTTGTCTGTCGGGAGGAACA

Downstream 100 bases:

>100_bases
TCCGCAGCGGCGAGCGCCAGCTCCGCCTCGCCGGCAAGTGCTCGATGCGGCGCCGGCCGGCCGATCGCGTGATGGTCGAG
CCCCGCCGCGCGCATCGCCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase 2 [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MAKERVLVTGGAAGIGAASVARCREEGYEVVVIDRIGDGIVADLSDPAATEAALAEALRGGPITRLVNNVGTVRPAPVEA
QTVADLDAVVSLNLRCSLQCVQALLPGMKAAGFGRIVNIASRAALGKEDRTAYAATKAGLIGMAKVWALELGRFGITANA
IGPGPIRTELFDRVNPPDDPRTTAIIEGIPVRRIGTPADVAHAIAYLLDQRSGFVTGQVLYVCGGMTVGAAGA

Sequences:

>Translated_233_residues
MAKERVLVTGGAAGIGAASVARCREEGYEVVVIDRIGDGIVADLSDPAATEAALAEALRGGPITRLVNNVGTVRPAPVEA
QTVADLDAVVSLNLRCSLQCVQALLPGMKAAGFGRIVNIASRAALGKEDRTAYAATKAGLIGMAKVWALELGRFGITANA
IGPGPIRTELFDRVNPPDDPRTTAIIEGIPVRRIGTPADVAHAIAYLLDQRSGFVTGQVLYVCGGMTVGAAGA
>Mature_232_residues
AKERVLVTGGAAGIGAASVARCREEGYEVVVIDRIGDGIVADLSDPAATEAALAEALRGGPITRLVNNVGTVRPAPVEAQ
TVADLDAVVSLNLRCSLQCVQALLPGMKAAGFGRIVNIASRAALGKEDRTAYAATKAGLIGMAKVWALELGRFGITANAI
GPGPIRTELFDRVNPPDDPRTTAIIEGIPVRRIGTPADVAHAIAYLLDQRSGFVTGQVLYVCGGMTVGAAGA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=32.3651452282158, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=31.6, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=30.1255230125523, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=28.0487804878049, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI59889578, Length=197, Percent_Identity=31.4720812182741, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=28.2258064516129, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI66933014, Length=218, Percent_Identity=26.1467889908257, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4503301, Length=201, Percent_Identity=29.3532338308458, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI7657478, Length=246, Percent_Identity=30.4878048780488, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=31.2236286919831, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=32.520325203252, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=27.9352226720648, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=29.9180327868852, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789208, Length=181, Percent_Identity=33.1491712707182, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=31.5508021390374, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787905, Length=166, Percent_Identity=33.7349397590361, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788459, Length=173, Percent_Identity=33.5260115606936, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=31.5573770491803, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=29.4605809128631, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=23.7154150197628, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786812, Length=246, Percent_Identity=28.0487804878049, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=28.1746031746032, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=30.1652892561983, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=31.8367346938775, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=224, Percent_Identity=28.125, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=28.7937743190661, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=26.7175572519084, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=26.9076305220884, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=28.8617886178862, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=27.6422764227642, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=24.8091603053435, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=26.5625, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=202, Percent_Identity=27.7227722772277, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=31.6666666666667, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=31.5352697095436, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=27.3469387755102, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=27.5720164609054, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=29.0983606557377, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356301, Length=208, Percent_Identity=30.2884615384615, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI18859837, Length=203, Percent_Identity=30.5418719211823, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=27.6422764227642, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=28.7449392712551, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 23912; Mature: 23781

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKERVLVTGGAAGIGAASVARCREEGYEVVVIDRIGDGIVADLSDPAATEAALAEALRG
CCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHCC
GPITRLVNNVGTVRPAPVEAQTVADLDAVVSLNLRCSLQCVQALLPGMKAAGFGRIVNIA
CHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCCCHHHHHHH
SRAALGKEDRTAYAATKAGLIGMAKVWALELGRFGITANAIGPGPIRTELFDRVNPPDDP
HHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCCCCC
RTTAIIEGIPVRRIGTPADVAHAIAYLLDQRSGFVTGQVLYVCGGMTVGAAGA
CCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEECCCCC
>Mature Secondary Structure 
AKERVLVTGGAAGIGAASVARCREEGYEVVVIDRIGDGIVADLSDPAATEAALAEALRG
CCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHCC
GPITRLVNNVGTVRPAPVEAQTVADLDAVVSLNLRCSLQCVQALLPGMKAAGFGRIVNIA
CHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCCCHHHHHHH
SRAALGKEDRTAYAATKAGLIGMAKVWALELGRFGITANAIGPGPIRTELFDRVNPPDDP
HHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCCCCC
RTTAIIEGIPVRRIGTPADVAHAIAYLLDQRSGFVTGQVLYVCGGMTVGAAGA
CCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]