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The map label for this gene is nrdJ [H]

Identifier: 148259189

GI number: 148259189

Start: 195512

End: 197038

Strand: Reverse

Name: nrdJ [H]

Synonym: Acry_0169

Alternate gene names: 148259189

Gene position: 197038-195512 (Counterclockwise)

Preceding gene: 148259195

Following gene: 148259188

Centisome position: 5.81

GC content: 73.15

Gene sequence:

>1527_bases
ATGAGGAAGGATCCCGCCAGCAGGCATCGCCCGACACCGCACCGCGCGTGGCGCGGCATCCGGCTCAAACGGGTCGAGAT
CGGGATCGATCCCGATGCCGCACCCGAACCCGCCATCATTCCCGCCGACTGGAGCGATCAGGCCGCCGCCGGGCTGGTGG
CGCTACGCGCCGATCGCTCGATGATCGGGGTCGACCAGGCGGCCGATGCCTGGATCGCGCCGCTTGCCGCCGCCGCGGAG
CGTCTGGGTCGCGGCGAGGATGTCGCGTCCACGCTGCACCGGCTGGTCGCAACGCGCCGCGCCGCGCCGAGCCCTGGCAT
CTGGCAGGGCCGTGCCGAGCCGGTGCCTGGCTTCGTCTTCAACCTGCCCCAGTTCCTCGACGAGAGCGGCATGTTCGACG
CCGCCGCGTTCGGCGAGGCGGTCGAACACGCGGTGCTCGCCCTCTCGCTGGCGCAACCTTCGGCCCAGCGCCTCGCACTC
GGCATGGCCGACCTCGCCCTGCTGCTGGCGCGCCTCGATATCGATTACGCGAGCCCCACGGCGCGCGACGTGGCCGCGAC
GATCGGCGCGCTGCTCGCCGCCCATGCGGATATCACCTCGGCCGGGCTGCTGGCGCGGGGCATCGCGCCGGGATGCGCCA
TCACGCCGGTTCCGGTTCCCGCCAGTTGCGCCCAGCCCGGCCTGCGCGCCGCCTTGCTCGACGCGCGCGAGCGGGCCCTG
GCGTGCGGCCTGCGCCAGCATCGCAGCCTGACCGGGCTGCTGCCGCCGGGGCCGGTGGAGATGCTGCTCGACGTCGAGAC
GGTTGGGATCGCAGCACCGCTCTCGGCGCTGGACTCCGAGGGCGGGCTCGCCCGCTGGGCGCGGGCGCGGCTTGCCGCCT
CCGGCCGTACGGCCGAGTCGGCGCTGGCCGCGAGCCTGGCCGGCGCCGATCCGTTCGGCGTGACCGATGCCGCCGGCATC
GCCGCAATGCGCGAGGCCATCGCACCGGTCTGCGCCATCCTGCCCGAGGTGCCGTCCCTCCCCGCGCCGCGCGCGGCCTC
CGCCGGGCGCGGCAAGCTGCCGGCGCGCCGCGGCGGCTACACCCAGAAGGTTTCGGTGGGCGGGCACCGGCTATTCCTGC
GCACCGGTGAATATCCGGACGGGCGGCTGGGCGAGATCATGATCTCGCTACCGAAGGACTCCGCAACGCTGCGCGGCATG
GCCGAGGCGTTCGCCGGCGCGGTCAGCATCGGGTTGCAGCATGGCGTGCCTCTGGATGAATTCGTCGATGAATTTGCCTT
CACCCGCTTCGCGCCCGCCGGCGCGGTGGAAGGCGACGCAATGATCAGCCAGGCGACCTCGCTCCTCGACTATGTGTTCC
GGCACCTGGCCGCGACCTATTCGCAGCGGCCCGATCTCGCGGCGCTCGACCTTGCCGACGATGCGGCTGGTGTCGATGCC
GCCGCTCCGCTGCTGCCGCTGGACCTGCCGGAGACCGGAACCGGCCGGCCGAAGCGCCAGCGTCCCGTCCTGAAACTCGT
GAGCTGA

Upstream 100 bases:

>100_bases
CCGGCTTATCCACAAGATTTTGTGGCCGTGACCTGAATTTTCCACAAGATGACGCCGACCGCCGCTGGAAACCCCATGAG
GAACACGTTAGGCTGAGGGC

Downstream 100 bases:

>100_bases
TCCATGGATATACGCGCGCGCCTCGCCGAGAACGGCATAACCCTTCCGCCCGCGGCGAAGGCCGTGGCGAATTACGTGCC
GGTGGTGGTCGCCGGTGGAA

Product: hypothetical protein

Products: NA

Alternate protein names: Ribonucleoside-diphosphate reductase nrdJ [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MRKDPASRHRPTPHRAWRGIRLKRVEIGIDPDAAPEPAIIPADWSDQAAAGLVALRADRSMIGVDQAADAWIAPLAAAAE
RLGRGEDVASTLHRLVATRRAAPSPGIWQGRAEPVPGFVFNLPQFLDESGMFDAAAFGEAVEHAVLALSLAQPSAQRLAL
GMADLALLLARLDIDYASPTARDVAATIGALLAAHADITSAGLLARGIAPGCAITPVPVPASCAQPGLRAALLDARERAL
ACGLRQHRSLTGLLPPGPVEMLLDVETVGIAAPLSALDSEGGLARWARARLAASGRTAESALAASLAGADPFGVTDAAGI
AAMREAIAPVCAILPEVPSLPAPRAASAGRGKLPARRGGYTQKVSVGGHRLFLRTGEYPDGRLGEIMISLPKDSATLRGM
AEAFAGAVSIGLQHGVPLDEFVDEFAFTRFAPAGAVEGDAMISQATSLLDYVFRHLAATYSQRPDLAALDLADDAAGVDA
AAPLLPLDLPETGTGRPKRQRPVLKLVS

Sequences:

>Translated_508_residues
MRKDPASRHRPTPHRAWRGIRLKRVEIGIDPDAAPEPAIIPADWSDQAAAGLVALRADRSMIGVDQAADAWIAPLAAAAE
RLGRGEDVASTLHRLVATRRAAPSPGIWQGRAEPVPGFVFNLPQFLDESGMFDAAAFGEAVEHAVLALSLAQPSAQRLAL
GMADLALLLARLDIDYASPTARDVAATIGALLAAHADITSAGLLARGIAPGCAITPVPVPASCAQPGLRAALLDARERAL
ACGLRQHRSLTGLLPPGPVEMLLDVETVGIAAPLSALDSEGGLARWARARLAASGRTAESALAASLAGADPFGVTDAAGI
AAMREAIAPVCAILPEVPSLPAPRAASAGRGKLPARRGGYTQKVSVGGHRLFLRTGEYPDGRLGEIMISLPKDSATLRGM
AEAFAGAVSIGLQHGVPLDEFVDEFAFTRFAPAGAVEGDAMISQATSLLDYVFRHLAATYSQRPDLAALDLADDAAGVDA
AAPLLPLDLPETGTGRPKRQRPVLKLVS
>Mature_508_residues
MRKDPASRHRPTPHRAWRGIRLKRVEIGIDPDAAPEPAIIPADWSDQAAAGLVALRADRSMIGVDQAADAWIAPLAAAAE
RLGRGEDVASTLHRLVATRRAAPSPGIWQGRAEPVPGFVFNLPQFLDESGMFDAAAFGEAVEHAVLALSLAQPSAQRLAL
GMADLALLLARLDIDYASPTARDVAATIGALLAAHADITSAGLLARGIAPGCAITPVPVPASCAQPGLRAALLDARERAL
ACGLRQHRSLTGLLPPGPVEMLLDVETVGIAAPLSALDSEGGLARWARARLAASGRTAESALAASLAGADPFGVTDAAGI
AAMREAIAPVCAILPEVPSLPAPRAASAGRGKLPARRGGYTQKVSVGGHRLFLRTGEYPDGRLGEIMISLPKDSATLRGM
AEAFAGAVSIGLQHGVPLDEFVDEFAFTRFAPAGAVEGDAMISQATSLLDYVFRHLAATYSQRPDLAALDLADDAAGVDA
AAPLLPLDLPETGTGRPKRQRPVLKLVS

Specific function: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen [H]

COG id: COG0209

COG function: function code F; Ribonucleotide reductase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase class-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002876
- InterPro:   IPR017856
- InterPro:   IPR013344
- InterPro:   IPR000788
- InterPro:   IPR013678 [H]

Pfam domain/function: PF08471 Ribonuc_red_2_N; PF02867 Ribonuc_red_lgC [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 52664; Mature: 52664

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKDPASRHRPTPHRAWRGIRLKRVEIGIDPDAAPEPAIIPADWSDQAAAGLVALRADRS
CCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCEECCCCCCHHHHCEEEEECCCC
MIGVDQAADAWIAPLAAAAERLGRGEDVASTLHRLVATRRAAPSPGIWQGRAEPVPGFVF
HHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
NLPQFLDESGMFDAAAFGEAVEHAVLALSLAQPSAQRLALGMADLALLLARLDIDYASPT
HCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
ARDVAATIGALLAAHADITSAGLLARGIAPGCAITPVPVPASCAQPGLRAALLDARERAL
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEECCCCCCHHHCCCCHHHHHHHHHHHHH
ACGLRQHRSLTGLLPPGPVEMLLDVETVGIAAPLSALDSEGGLARWARARLAASGRTAES
HHHHHHHCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
ALAASLAGADPFGVTDAAGIAAMREAIAPVCAILPEVPSLPAPRAASAGRGKLPARRGGY
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
TQKVSVGGHRLFLRTGEYPDGRLGEIMISLPKDSATLRGMAEAFAGAVSIGLQHGVPLDE
CEEEECCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
FVDEFAFTRFAPAGAVEGDAMISQATSLLDYVFRHLAATYSQRPDLAALDLADDAAGVDA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
AAPLLPLDLPETGTGRPKRQRPVLKLVS
CCCCCCCCCCCCCCCCCHHCCCHHHHCC
>Mature Secondary Structure
MRKDPASRHRPTPHRAWRGIRLKRVEIGIDPDAAPEPAIIPADWSDQAAAGLVALRADRS
CCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCEECCCCCCHHHHCEEEEECCCC
MIGVDQAADAWIAPLAAAAERLGRGEDVASTLHRLVATRRAAPSPGIWQGRAEPVPGFVF
HHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
NLPQFLDESGMFDAAAFGEAVEHAVLALSLAQPSAQRLALGMADLALLLARLDIDYASPT
HCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
ARDVAATIGALLAAHADITSAGLLARGIAPGCAITPVPVPASCAQPGLRAALLDARERAL
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEECCCCCCHHHCCCCHHHHHHHHHHHHH
ACGLRQHRSLTGLLPPGPVEMLLDVETVGIAAPLSALDSEGGLARWARARLAASGRTAES
HHHHHHHCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
ALAASLAGADPFGVTDAAGIAAMREAIAPVCAILPEVPSLPAPRAASAGRGKLPARRGGY
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
TQKVSVGGHRLFLRTGEYPDGRLGEIMISLPKDSATLRGMAEAFAGAVSIGLQHGVPLDE
CEEEECCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
FVDEFAFTRFAPAGAVEGDAMISQATSLLDYVFRHLAATYSQRPDLAALDLADDAAGVDA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
AAPLLPLDLPETGTGRPKRQRPVLKLVS
CCCCCCCCCCCCCCCCCHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]