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The map label for this gene is cobA [H]

Identifier: 148243444

GI number: 148243444

Start: 2040459

End: 2041049

Strand: Direct

Name: cobA [H]

Synonym: SynRCC307_2345

Alternate gene names: 148243444

Gene position: 2040459-2041049 (Clockwise)

Preceding gene: 148243440

Following gene: 148243445

Centisome position: 91.71

GC content: 64.3

Gene sequence:

>591_bases
GTGATTTTTCGCCGCTACATTCAGGAGCACCCCCGCTTTGGACGGCCCATGCTCAGCCGCGTTGCTGAACGCCACCACAG
GCCGTCCACAGCACCCTTGCGGCTGGTGGTTCGCGAGCCCGAAGGCCTGCTGCAGGTCCACACCGCCAGCTTTCGCGGCA
GTTTTGCCAGCGTGTTCAGCGAAGCCCTGCGCTCCGCGGGCCTCGGCAGCCGCGTGCTGATCTGCCAATTCCTGCGCGGC
GGCGTTGATCAAGGCCCCCACCAACCTGTGCAGATGTGTGGGCGCCTCACTTGGCTGCGCCCTGCTGTGACGAGCTGCCT
GCAGGCCGAGCACAGCGCCGATGACCAGCAAGCCGTGCAGGAGCTATGGCAAGAGACCCAGCGCCAAATCCTGGAAGAAG
CGCCTGATCTCGTGGTTCTTGATGAACTCGGGCTCGCGTTGGACTACGGCTTACTGGATGCCAATGCTGTGATCAGCACC
CTGCAGACCCGCCCGGGGCGAATGGATGTGATCCTGACCGGACCTGCCGTGCCGGAGCCTGTGATGGCAATGGCCGATCA
AGTCACCGAACTGCGCCGCGACCGATGCTGA

Upstream 100 bases:

>100_bases
CCGGCTTGACAGTGCTTGTAGCAATGAACACCGTCCGGCCTGGTCGCGATCAGCAGTAGTACAGACATTCACACTACTGG
TGGTGCCAGTCACTTGATTC

Downstream 100 bases:

>100_bases
AGAACGATCGCTGGATCAACGAACAAGCTGAGCATGGGCTCCTGGAACCCTTCCAGCCCACCTTGGTGCGCCATCTCGAT
CCTGAGAACCGCAGCGGCGC

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MIFRRYIQEHPRFGRPMLSRVAERHHRPSTAPLRLVVREPEGLLQVHTASFRGSFASVFSEALRSAGLGSRVLICQFLRG
GVDQGPHQPVQMCGRLTWLRPAVTSCLQAEHSADDQQAVQELWQETQRQILEEAPDLVVLDELGLALDYGLLDANAVIST
LQTRPGRMDVILTGPAVPEPVMAMADQVTELRRDRC

Sequences:

>Translated_196_residues
MIFRRYIQEHPRFGRPMLSRVAERHHRPSTAPLRLVVREPEGLLQVHTASFRGSFASVFSEALRSAGLGSRVLICQFLRG
GVDQGPHQPVQMCGRLTWLRPAVTSCLQAEHSADDQQAVQELWQETQRQILEEAPDLVVLDELGLALDYGLLDANAVIST
LQTRPGRMDVILTGPAVPEPVMAMADQVTELRRDRC
>Mature_196_residues
MIFRRYIQEHPRFGRPMLSRVAERHHRPSTAPLRLVVREPEGLLQVHTASFRGSFASVFSEALRSAGLGSRVLICQFLRG
GVDQGPHQPVQMCGRLTWLRPAVTSCLQAEHSADDQQAVQELWQETQRQILEEAPDLVVLDELGLALDYGLLDANAVIST
LQTRPGRMDVILTGPAVPEPVMAMADQVTELRRDRC

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=192, Percent_Identity=27.0833333333333, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 21929; Mature: 21929

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFRRYIQEHPRFGRPMLSRVAERHHRPSTAPLRLVVREPEGLLQVHTASFRGSFASVFS
CHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHH
EALRSAGLGSRVLICQFLRGGVDQGPHQPVQMCGRLTWLRPAVTSCLQAEHSADDQQAVQ
HHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ELWQETQRQILEEAPDLVVLDELGLALDYGLLDANAVISTLQTRPGRMDVILTGPAVPEP
HHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHH
VMAMADQVTELRRDRC
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIFRRYIQEHPRFGRPMLSRVAERHHRPSTAPLRLVVREPEGLLQVHTASFRGSFASVFS
CHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHH
EALRSAGLGSRVLICQFLRGGVDQGPHQPVQMCGRLTWLRPAVTSCLQAEHSADDQQAVQ
HHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ELWQETQRQILEEAPDLVVLDELGLALDYGLLDANAVISTLQTRPGRMDVILTGPAVPEP
HHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHH
VMAMADQVTELRRDRC
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916712; 11677609; 7860601; 2403541 [H]