Click here to switch to the map view.

The map label for this gene is aroC

Identifier: 148243289

GI number: 148243289

Start: 1900698

End: 1901780

Strand: Direct

Name: aroC

Synonym: SynRCC307_2190

Alternate gene names: 148243289

Gene position: 1900698-1901780 (Clockwise)

Preceding gene: 148243287

Following gene: 148243295

Centisome position: 85.43

GC content: 62.79

Gene sequence:

>1083_bases
ATGGGCAGCAGTTTCGGCCATCTCTTCCGCATCAGCACGTTCGGGGAATCCCACGGCGGCGGTGTTGGCGTGATTGTCGA
TGGGTGTCCTCCGCGCTTAGCCATCGACATCGAGGCCGTCCAAGCCGAACTAGACCGGCGCAAGCCTGGTCAAAGCAAGA
TCACGACCCCACGCAAAGAGGATGACCGCGTTGAGGCACTCAGCGGTCTGCTCGATGGGGTCAGCCTCGGCACCCCGATT
GCGATGGTGGTGCGCAACAAAGACCAGCGGCCTGGCGATTACAAGGAAATGCAGGTGGCTTTTCGGCCCTCCCACGCCGA
TGCCACCTACCAAAGCAAGTACGGCATTCAGGCGCGCAGCGGCGGTGGCAGGGCATCAGCGCGTGAAACCATCGGCCGCG
TGGCCGCCGGAGCCATTGCCAAGCAAATGCTCCGGCAGCTGCATGGCACCGAAGTGCTGGCCTGGGTGAAACGCATCCAC
ACCCTGGAAGCCAACATCGATCCAGCAGTGCCCACGCTGGACGCGGTGGAGTCCAACATCGTGCGCTGCCCCGATGCCGC
CATGGCGGAGCAGATGATCGAGCGCATTGAGTCCATCGGGCGTGATGGCGACTCCTGCGGCGGGGTCATCGAATGCGTGG
TGCGCCGGCCACCCACGGGGCTGGGAATGCCGGTCTTCGACAAGTTGGAGGCCGATCTCGCCAAGGCCGTGATGTCACTA
CCGGCCACCAAAGGATTTGAGATTGGCTCGGGCTTTGCAGGCACCACCCTTCTGGGCAGCCAGCACAACGATGCATTCCT
GCCAACTAGCGACGGCAGCTTGCACACCGCCACCAACAATTCTGGTGGGATCCAAGGCGGAATCAGCAATGGCGAGCCGA
TCGTGCTGCGGGTGGCTTTCAAGCCAACCGCCACGATCCGCAAAGAACAACAAACAATCAACGCCAGTGGCGAAGCCACA
ACACTGGCGGCGAAAGGACGCCACGATCCCTGCGTGCTACCCAGGGCCGTGCCCATGGTGGAAGCCATGGTGGCCCTGGT
GCTCGCTGATCACGCTCTACGCCAACGCGGCCAGTGCGGTTGA

Upstream 100 bases:

>100_bases
AGCCTTCGACAGGCCTTTGGGAGCTCTCCAGAAGGATTCAAGAAACAAACAAACGCATGACGCGCTCTGGCCCGTACGCT
CGATGCAGTTTCAGCTGGCC

Downstream 100 bases:

>100_bases
GCTGAACTGGTTCAGCTAAGGGTTGCGGTTGCGCTGCCCACTCCATTGCTGGAGGTTGCGGCGCCAGAACCCAACTTGCT
GGCTGCTTTGGCCATCCGCT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MGSSFGHLFRISTFGESHGGGVGVIVDGCPPRLAIDIEAVQAELDRRKPGQSKITTPRKEDDRVEALSGLLDGVSLGTPI
AMVVRNKDQRPGDYKEMQVAFRPSHADATYQSKYGIQARSGGGRASARETIGRVAAGAIAKQMLRQLHGTEVLAWVKRIH
TLEANIDPAVPTLDAVESNIVRCPDAAMAEQMIERIESIGRDGDSCGGVIECVVRRPPTGLGMPVFDKLEADLAKAVMSL
PATKGFEIGSGFAGTTLLGSQHNDAFLPTSDGSLHTATNNSGGIQGGISNGEPIVLRVAFKPTATIRKEQQTINASGEAT
TLAAKGRHDPCVLPRAVPMVEAMVALVLADHALRQRGQCG

Sequences:

>Translated_360_residues
MGSSFGHLFRISTFGESHGGGVGVIVDGCPPRLAIDIEAVQAELDRRKPGQSKITTPRKEDDRVEALSGLLDGVSLGTPI
AMVVRNKDQRPGDYKEMQVAFRPSHADATYQSKYGIQARSGGGRASARETIGRVAAGAIAKQMLRQLHGTEVLAWVKRIH
TLEANIDPAVPTLDAVESNIVRCPDAAMAEQMIERIESIGRDGDSCGGVIECVVRRPPTGLGMPVFDKLEADLAKAVMSL
PATKGFEIGSGFAGTTLLGSQHNDAFLPTSDGSLHTATNNSGGIQGGISNGEPIVLRVAFKPTATIRKEQQTINASGEAT
TLAAKGRHDPCVLPRAVPMVEAMVALVLADHALRQRGQCG
>Mature_359_residues
GSSFGHLFRISTFGESHGGGVGVIVDGCPPRLAIDIEAVQAELDRRKPGQSKITTPRKEDDRVEALSGLLDGVSLGTPIA
MVVRNKDQRPGDYKEMQVAFRPSHADATYQSKYGIQARSGGGRASARETIGRVAAGAIAKQMLRQLHGTEVLAWVKRIHT
LEANIDPAVPTLDAVESNIVRCPDAAMAEQMIERIESIGRDGDSCGGVIECVVRRPPTGLGMPVFDKLEADLAKAVMSLP
ATKGFEIGSGFAGTTLLGSQHNDAFLPTSDGSLHTATNNSGGIQGGISNGEPIVLRVAFKPTATIRKEQQTINASGEATT
LAAKGRHDPCVLPRAVPMVEAMVALVLADHALRQRGQCG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=357, Percent_Identity=47.0588235294118, Blast_Score=297, Evalue=6e-82,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=55.3133514986376, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_SYNR3 (A5GW34)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001228446.1
- ProteinModelPortal:   A5GW34
- SMR:   A5GW34
- STRING:   A5GW34
- GeneID:   5157205
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_2190
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   TATIGKE
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38030; Mature: 37899

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSFGHLFRISTFGESHGGGVGVIVDGCPPRLAIDIEAVQAELDRRKPGQSKITTPRKE
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
DDRVEALSGLLDGVSLGTPIAMVVRNKDQRPGDYKEMQVAFRPSHADATYQSKYGIQARS
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHEEEEECCCCCCCCHHHHCCCEECC
GGGRASARETIGRVAAGAIAKQMLRQLHGTEVLAWVKRIHTLEANIDPAVPTLDAVESNI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCC
VRCPDAAMAEQMIERIESIGRDGDSCGGVIECVVRRPPTGLGMPVFDKLEADLAKAVMSL
EECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
PATKGFEIGSGFAGTTLLGSQHNDAFLPTSDGSLHTATNNSGGIQGGISNGEPIVLRVAF
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEE
KPTATIRKEQQTINASGEATTLAAKGRHDPCVLPRAVPMVEAMVALVLADHALRQRGQCG
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GSSFGHLFRISTFGESHGGGVGVIVDGCPPRLAIDIEAVQAELDRRKPGQSKITTPRKE
CCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
DDRVEALSGLLDGVSLGTPIAMVVRNKDQRPGDYKEMQVAFRPSHADATYQSKYGIQARS
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHEEEEECCCCCCCCHHHHCCCEECC
GGGRASARETIGRVAAGAIAKQMLRQLHGTEVLAWVKRIHTLEANIDPAVPTLDAVESNI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCC
VRCPDAAMAEQMIERIESIGRDGDSCGGVIECVVRRPPTGLGMPVFDKLEADLAKAVMSL
EECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
PATKGFEIGSGFAGTTLLGSQHNDAFLPTSDGSLHTATNNSGGIQGGISNGEPIVLRVAF
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEE
KPTATIRKEQQTINASGEATTLAAKGRHDPCVLPRAVPMVEAMVALVLADHALRQRGQCG
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA