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The map label for this gene is lon [H]

Identifier: 148243271

GI number: 148243271

Start: 1881550

End: 1882197

Strand: Direct

Name: lon [H]

Synonym: SynRCC307_2172

Alternate gene names: 148243271

Gene position: 1881550-1882197 (Clockwise)

Preceding gene: 148243270

Following gene: 148243272

Centisome position: 84.57

GC content: 58.33

Gene sequence:

>648_bases
ATGACTGAGCTGGCCGTACGGGAGCTGCCTCTTTTCCCATTGCCAGACGTGGTGCTCTTCCCCCAGGAAGTGCTGCCACT
GCATATTTTTGAGCACCGTTACCGCATGATGTTGCGCACGGTGCTTGATAGTGACCGCCGTTTTGGGGTAGTGCGTTGGG
ATCCCGAATCCAAGCAAATGGCGCAGATCGGATGCTGTGCCGAGGTCCTCAAATGTGAAACCGGTGACGACGACCGCAGC
AACATCGTCACCATGGGCCAGCAGCGCTTCCGCGTGTTGGAAATCGTGCGAGAAGCCCCGTTCATGGTGGGGTTGGTGAG
CTGGATGGAGGACGAACCTCCGGTGGATGACATCCAACCGCTCGCCTCGGATGTGCAAGTGGCTTTAAAGGATGTGGTGG
ATCTCTCCGCCAAGTTGCTGGGTCACAAGACCGTGCTCCCCGATGACCTCCCCGACCTACCCAGAGAGTTGTCCTTCTGG
GTTGGTGGCCATCTCGGTGGTGCTGTCGCCGACCATCAACAGCAGCTGCTGGAACTCACCTCGACTGGCGAAAGGCTGCA
GTTGGAATTTGAGCTTTTGGACCACACCCGCCGCCAACTCGCTGCCCGCACGGTGCTCAAAGACACCTTCAAGGATCTGG
AGGGATGA

Upstream 100 bases:

>100_bases
CTGGATCTTCCCAGTGGTGTTGATATCGAAGTGAAGCTCTGATTCAGCCGGCCCGCTGGCCCTGAATGCTTCTTAGGATG
GCTTCCGTTCTCCCCACGCC

Downstream 100 bases:

>100_bases
GCCTGCTTTTCACAGGGCTGGTGCTCCTCACTGGCTTGTTGGGCGTGGGACTAGTGGTTTGGTATGTGCTGCCTCGGCGC
TTTCGCGGCAGCGAAAGCGT

Product: Lon protease domain-containing protein

Products: NA

Alternate protein names: ATP-dependent protease La [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MTELAVRELPLFPLPDVVLFPQEVLPLHIFEHRYRMMLRTVLDSDRRFGVVRWDPESKQMAQIGCCAEVLKCETGDDDRS
NIVTMGQQRFRVLEIVREAPFMVGLVSWMEDEPPVDDIQPLASDVQVALKDVVDLSAKLLGHKTVLPDDLPDLPRELSFW
VGGHLGGAVADHQQQLLELTSTGERLQLEFELLDHTRRQLAARTVLKDTFKDLEG

Sequences:

>Translated_215_residues
MTELAVRELPLFPLPDVVLFPQEVLPLHIFEHRYRMMLRTVLDSDRRFGVVRWDPESKQMAQIGCCAEVLKCETGDDDRS
NIVTMGQQRFRVLEIVREAPFMVGLVSWMEDEPPVDDIQPLASDVQVALKDVVDLSAKLLGHKTVLPDDLPDLPRELSFW
VGGHLGGAVADHQQQLLELTSTGERLQLEFELLDHTRRQLAARTVLKDTFKDLEG
>Mature_214_residues
TELAVRELPLFPLPDVVLFPQEVLPLHIFEHRYRMMLRTVLDSDRRFGVVRWDPESKQMAQIGCCAEVLKCETGDDDRSN
IVTMGQQRFRVLEIVREAPFMVGLVSWMEDEPPVDDIQPLASDVQVALKDVVDLSAKLLGHKTVLPDDLPDLPRELSFWV
GGHLGGAVADHQQQLLELTSTGERLQLEFELLDHTRRQLAARTVLKDTFKDLEG

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG2802

COG function: function code R; Uncharacterized protein, similar to the N-terminal domain of Lon protease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

Organism=Homo sapiens, GI148528975, Length=166, Percent_Identity=28.9156626506024, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 24465; Mature: 24333

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELAVRELPLFPLPDVVLFPQEVLPLHIFEHRYRMMLRTVLDSDRRFGVVRWDPESKQM
CCCCHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHH
AQIGCCAEVLKCETGDDDRSNIVTMGQQRFRVLEIVREAPFMVGLVSWMEDEPPVDDIQP
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHH
LASDVQVALKDVVDLSAKLLGHKTVLPDDLPDLPRELSFWVGGHLGGAVADHQQQLLELT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
STGERLQLEFELLDHTRRQLAARTVLKDTFKDLEG
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TELAVRELPLFPLPDVVLFPQEVLPLHIFEHRYRMMLRTVLDSDRRFGVVRWDPESKQM
CCCHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHH
AQIGCCAEVLKCETGDDDRSNIVTMGQQRFRVLEIVREAPFMVGLVSWMEDEPPVDDIQP
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHH
LASDVQVALKDVVDLSAKLLGHKTVLPDDLPDLPRELSFWVGGHLGGAVADHQQQLLELT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
STGERLQLEFELLDHTRRQLAARTVLKDTFKDLEG
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA