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The map label for this gene is rnz [H]

Identifier: 148242938

GI number: 148242938

Start: 1602489

End: 1603490

Strand: Direct

Name: rnz [H]

Synonym: SynRCC307_1839

Alternate gene names: 148242938

Gene position: 1602489-1603490 (Clockwise)

Preceding gene: 148242934

Following gene: 148242939

Centisome position: 72.02

GC content: 63.97

Gene sequence:

>1002_bases
TTGCCGTGGCACCATCAAAGCTGGGGCAGCCAACCAGCGCCATTGCAGGTCACTTTTCTCGGCACCAGTTCCGGAGTCCC
GAGCCGCAGCCGCAATGTCTCTGCGGTGGCTCTGCGTCTGCCGCAGCGCGCCGACCTGTGGCTGTTCGACTGCGGCGAAG
CCACCCAACACCAATTCCTGCGCAGCGAGCTGCGTGTCTCCCAGCTGAGGCGCATCTTCATCACCCACATGCATGGAGAC
CATGTCTTCGGCTTGCCAGGCTTGCTGGCCAGCCTGGGCATGGCGGGAACCTGTGATGGGGTCGACCTTTATGGCCCCGA
ACCCCTGGAGGCCTTTGTGCTGAGTGCCCTGCAGCACTCCGCCACTCGGATTGGCTATCCCCTGCGCTTTCACCCGGTGG
AATCAGCGGCCAACAGCGGCGAACCCCTGCTCATCGATGGGGAGTTCAGCGTCTGCTGCGCACCGCTCAAACACCGGGTG
CCTGCCTTTGGCTATCGCGTGCAGCAAAGCGAGCGCCCAGGCCGCTTTGACATTGCCAAGGCCAAAGCGATGCGGCTGCC
GCCAGGGCCAGAGTTTGCGCGCCTCAAAGCCGGAGAAACCGTCACCTTTGCCGACGGGCGGCGCATCGATGGCCGCGAGC
TCTGCGGGCCCAGGCAGCCGGGATGCTCCGTTGTTTATTGCACCGACACGGTGTTCAGCGAGCGCGCTGTGGCCTTGGCC
CAAGGGGCTGATCTGCTCATCCACGAAGCCACCTTTTCCCATCGCGATGCCGCGATGGCCTATCAACGCCAGCACTCCAC
CAGCACCATGGCGGCGCAGACCGCAGCGGAAGCAGGCGTGCAGCAACTGGCCCTCACGCACCTGAGCCCGCGCTACGTGC
CTGGGGCGACCGAAAGCCCGGATGATTTGTTGCAGGAAGCCAAGGCGATCTTTCCCAACACCGTGCTGGCCAAGGACTTC
CTCAGCATCGAAGTGAGCACCATGGCCTGCAACAGTCTGTGA

Upstream 100 bases:

>100_bases
CCCGCACCTGGGGCTCTTGGGCGGAGCGGGCTGCCCCAGGCCAGAGCAGCAGGAGCAGCCCCATGAGGCTGCCAAAGGTC
CAACGCAGGTTCATTGAGCT

Downstream 100 bases:

>100_bases
GTGGCATGACGATTCAGCCCCGGAGCAGTGCCTGCGCGTGATACAAGGGCTCAGGAGACTGTCTCTTTTGCCCCACTCCA
TGCGCACCGTTCTTCAGGGT

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MPWHHQSWGSQPAPLQVTFLGTSSGVPSRSRNVSAVALRLPQRADLWLFDCGEATQHQFLRSELRVSQLRRIFITHMHGD
HVFGLPGLLASLGMAGTCDGVDLYGPEPLEAFVLSALQHSATRIGYPLRFHPVESAANSGEPLLIDGEFSVCCAPLKHRV
PAFGYRVQQSERPGRFDIAKAKAMRLPPGPEFARLKAGETVTFADGRRIDGRELCGPRQPGCSVVYCTDTVFSERAVALA
QGADLLIHEATFSHRDAAMAYQRQHSTSTMAAQTAAEAGVQQLALTHLSPRYVPGATESPDDLLQEAKAIFPNTVLAKDF
LSIEVSTMACNSL

Sequences:

>Translated_333_residues
MPWHHQSWGSQPAPLQVTFLGTSSGVPSRSRNVSAVALRLPQRADLWLFDCGEATQHQFLRSELRVSQLRRIFITHMHGD
HVFGLPGLLASLGMAGTCDGVDLYGPEPLEAFVLSALQHSATRIGYPLRFHPVESAANSGEPLLIDGEFSVCCAPLKHRV
PAFGYRVQQSERPGRFDIAKAKAMRLPPGPEFARLKAGETVTFADGRRIDGRELCGPRQPGCSVVYCTDTVFSERAVALA
QGADLLIHEATFSHRDAAMAYQRQHSTSTMAAQTAAEAGVQQLALTHLSPRYVPGATESPDDLLQEAKAIFPNTVLAKDF
LSIEVSTMACNSL
>Mature_332_residues
PWHHQSWGSQPAPLQVTFLGTSSGVPSRSRNVSAVALRLPQRADLWLFDCGEATQHQFLRSELRVSQLRRIFITHMHGDH
VFGLPGLLASLGMAGTCDGVDLYGPEPLEAFVLSALQHSATRIGYPLRFHPVESAANSGEPLLIDGEFSVCCAPLKHRVP
AFGYRVQQSERPGRFDIAKAKAMRLPPGPEFARLKAGETVTFADGRRIDGRELCGPRQPGCSVVYCTDTVFSERAVALAQ
GADLLIHEATFSHRDAAMAYQRQHSTSTMAAQTAAEAGVQQLALTHLSPRYVPGATESPDDLLQEAKAIFPNTVLAKDFL
SIEVSTMACNSL

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Homo sapiens, GI8922122, Length=359, Percent_Identity=33.1476323119777, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI260166619, Length=214, Percent_Identity=30.3738317757009, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87082078, Length=313, Percent_Identity=43.1309904153355, Blast_Score=251, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 36216; Mature: 36084

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWHHQSWGSQPAPLQVTFLGTSSGVPSRSRNVSAVALRLPQRADLWLFDCGEATQHQFL
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHH
RSELRVSQLRRIFITHMHGDHVFGLPGLLASLGMAGTCDGVDLYGPEPLEAFVLSALQHS
HHHHHHHHHHHHHHEEECCCCEECHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ATRIGYPLRFHPVESAANSGEPLLIDGEFSVCCAPLKHRVPAFGYRVQQSERPGRFDIAK
HHHCCCCEEEECHHHCCCCCCEEEEECCHHEEEHHHHHCCCHHCEEECCCCCCCCEEHHH
AKAMRLPPGPEFARLKAGETVTFADGRRIDGRELCGPRQPGCSVVYCTDTVFSERAVALA
HHEECCCCCCCHHEECCCCEEEECCCCCCCCHHCCCCCCCCCEEEEEECCHHHHHHHHHH
QGADLLIHEATFSHRDAAMAYQRQHSTSTMAAQTAAEAGVQQLALTHLSPRYVPGATESP
CCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DDLLQEAKAIFPNTVLAKDFLSIEVSTMACNSL
HHHHHHHHHHCCCHHHHHHHHEEEEEHEECCCC
>Mature Secondary Structure 
PWHHQSWGSQPAPLQVTFLGTSSGVPSRSRNVSAVALRLPQRADLWLFDCGEATQHQFL
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHH
RSELRVSQLRRIFITHMHGDHVFGLPGLLASLGMAGTCDGVDLYGPEPLEAFVLSALQHS
HHHHHHHHHHHHHHEEECCCCEECHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ATRIGYPLRFHPVESAANSGEPLLIDGEFSVCCAPLKHRVPAFGYRVQQSERPGRFDIAK
HHHCCCCEEEECHHHCCCCCCEEEEECCHHEEEHHHHHCCCHHCEEECCCCCCCCEEHHH
AKAMRLPPGPEFARLKAGETVTFADGRRIDGRELCGPRQPGCSVVYCTDTVFSERAVALA
HHEECCCCCCCHHEECCCCEEEECCCCCCCCHHCCCCCCCCCEEEEEECCHHHHHHHHHH
QGADLLIHEATFSHRDAAMAYQRQHSTSTMAAQTAAEAGVQQLALTHLSPRYVPGATESP
CCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DDLLQEAKAIFPNTVLAKDFLSIEVSTMACNSL
HHHHHHHHHHCCCHHHHHHHHEEEEEHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA