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The map label for this gene is nblS [H]

Identifier: 148242922

GI number: 148242922

Start: 1586479

End: 1588413

Strand: Direct

Name: nblS [H]

Synonym: SynRCC307_1823

Alternate gene names: 148242922

Gene position: 1586479-1588413 (Clockwise)

Preceding gene: 148242921

Following gene: 148242926

Centisome position: 71.31

GC content: 62.38

Gene sequence:

>1935_bases
CTGCCAGCCCTCACCAGCGGCTGGTGGGCGGAGTTCAGCCTGCAGACCAAGTTGTTGGCCATCGCCACCTTGGTGGTCAG
CATCGTGATGACGGGGCTGACCTTCTTTGCCCTCAACGGCATTCAGACCGAAGCCCGCATGGGCGATACCCGCTACGCCC
GCGACCTGGGTTTGCTGCTGGCGAGCAACGTGACCCCATTGGCGGCTCAGGGCAATGACCGCGAGCTAGCCCGGGTCACC
GAAGAGTTCTGGCGCAGCAGCCGCAGCCTTCGCTACATCTTTTATGCCGACCCCGAGGGAGTGATCTACCTCGGCATCCC
GATCAGCAAGGTTGATAGCGGCAACGATCTACTGCTCAGCCGCCGGCTGGAACTGCCCTCTGACCTGCGTCAGCGCCCCC
AAAACCCTCTGATCCGCCAACACCTCACACCCGATGGGTTGGTCACCGACGTGTTCGTGCCGATGGTCAACGGCAAGAAC
TACCTCGGCGTGATGGCCCTGGGCGTCAATCCCAACGAAGCGGTGCTGGCCACAGCAGCCCTCACCCGCAATGTGACGGT
GGCGGTGTTCGTGTCGATCTGGGTGCTGGTGATCTTGGGCGCGGTGTTTAACGCCCTCACCATCACGCGGCCGGTGAAAG
AGCTGCTGCGCGGGGTGCGCTCAGTTGCCGATGGCGACTTCGGCGCGCGAATCGCTCTGCCGGTGGGCGGTGAGCTCGGT
GAGCTGCTCAATGGTTTCAACACCATGGCCACCCAATTGGAGGCCTACGACGAAGCCAATATCGAGGAGCTCACCGCTGC
CCAGGTGAAACAACAGTCGCTGATTGCCACCATGGCCGATGGCGCCCTGCTGCTTGATCCGGAGGGGCAGGTGGTGCTGG
TGAATCCAACAGCGCGGCGGCTGTTTCGCTGGGAGGGCCGCAAGCTGGAGGGCCAAGAGCTGCTCAGACTGCTGCCCGAC
AGCCTCACGATGGAGCTGCAGGAGCCATTCGATGCGGTGCGCAGCCGTGAGCGGGACAGCGCTGAGGTGCGCTGCTCGAT
CAATGAACCCAACCGCACCTTGCGCTTGGTGCTGCAAGCGGTGCGCGATGGCAGCGGCGAGACCCTTAAAGGGATTGCCG
TCACCGTTCAAGATCTAACGCGGGAGGTGGAGCTCAATGCAGCCCAGAGCCGTTTCATCAGCAACGTCTCCCATGAGCTG
CGGACGCCGCTCTTCAACATCAAGAGCTACGTGGAAACCCTCCACGACATGGGCGACCAGCTTGATGAGGAGATGACCCG
TGAGTTCCTGGCGACCGCCAATGCCGAAACCGATCGCCTCACCCGCTTAGTGAATGACGTGCTCGATCTCTCCAGGCTGG
AGTCCGATCGGGTCTGGAGCTTTGAGCCCACCGAGGTGGAAGCCGCGATGGAGCAAACCCTGCGCACCTACAAACTCAAC
GCGGATGACAAAGGCGTCAGCCTTGATTTGGCCGTGCCACCCTCATTGCCGCGCGTCCGCGGCAATTACGACCTCCTGCT
GCAGGTGTTCGACAACCTGGTAGGCAACGCAGTGAAGTTCAGCACCTCCGGCGACATGGTGCAGCTGCGGGCCTATCTAT
GGCCAGACACCTGCCCGATCAAAGCGGATGACGCCAGCTCCCCGCTGCCGCGTCTACGCGTGGAGGTGGCCGACAGCGGA
ACCGGCATCAGCGAAGAGGATTGCCGGCGGGTGTTTGAACGCTTCTACCGCGTTGAAAACGCTGTCCACACCGAAGCCGG
AACCGGCCTCGGCCTCTCGATCGTGCGGGGCATCCTGCAGAAGCACGGCAGCGATATTTCAATGGTGAGCGAGCTGGGCG
TGGGTACCACCTTCTGGTTCGATCTCCCCCTCGAGGGAGCCGATGAGGATGAGTTGATCGTCAACGCCGAACGCAAAGCG
TTGGCGTTGAGCTGA

Upstream 100 bases:

>100_bases
CGACATCGGCCATCAGGTGCGGCGTCTTTAGGCTGAGAGCAACCAAACCGGTCACCTGAGCAACTCCGCCGCTACTGAAA
CGCTGCCGTGGTGGCGCCGG

Downstream 100 bases:

>100_bases
TCTAACCAGGCTCGCTGTCGACGCCGCGGACAATGCGTGCCAACTCGTTGCGCTCGTCGGTGGTGATGCGGTGGGGCACA
CCACTGATGATCCGCTCGAA

Product: two-component system sensor histidine kinase NblS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MPALTSGWWAEFSLQTKLLAIATLVVSIVMTGLTFFALNGIQTEARMGDTRYARDLGLLLASNVTPLAAQGNDRELARVT
EEFWRSSRSLRYIFYADPEGVIYLGIPISKVDSGNDLLLSRRLELPSDLRQRPQNPLIRQHLTPDGLVTDVFVPMVNGKN
YLGVMALGVNPNEAVLATAALTRNVTVAVFVSIWVLVILGAVFNALTITRPVKELLRGVRSVADGDFGARIALPVGGELG
ELLNGFNTMATQLEAYDEANIEELTAAQVKQQSLIATMADGALLLDPEGQVVLVNPTARRLFRWEGRKLEGQELLRLLPD
SLTMELQEPFDAVRSRERDSAEVRCSINEPNRTLRLVLQAVRDGSGETLKGIAVTVQDLTREVELNAAQSRFISNVSHEL
RTPLFNIKSYVETLHDMGDQLDEEMTREFLATANAETDRLTRLVNDVLDLSRLESDRVWSFEPTEVEAAMEQTLRTYKLN
ADDKGVSLDLAVPPSLPRVRGNYDLLLQVFDNLVGNAVKFSTSGDMVQLRAYLWPDTCPIKADDASSPLPRLRVEVADSG
TGISEEDCRRVFERFYRVENAVHTEAGTGLGLSIVRGILQKHGSDISMVSELGVGTTFWFDLPLEGADEDELIVNAERKA
LALS

Sequences:

>Translated_644_residues
MPALTSGWWAEFSLQTKLLAIATLVVSIVMTGLTFFALNGIQTEARMGDTRYARDLGLLLASNVTPLAAQGNDRELARVT
EEFWRSSRSLRYIFYADPEGVIYLGIPISKVDSGNDLLLSRRLELPSDLRQRPQNPLIRQHLTPDGLVTDVFVPMVNGKN
YLGVMALGVNPNEAVLATAALTRNVTVAVFVSIWVLVILGAVFNALTITRPVKELLRGVRSVADGDFGARIALPVGGELG
ELLNGFNTMATQLEAYDEANIEELTAAQVKQQSLIATMADGALLLDPEGQVVLVNPTARRLFRWEGRKLEGQELLRLLPD
SLTMELQEPFDAVRSRERDSAEVRCSINEPNRTLRLVLQAVRDGSGETLKGIAVTVQDLTREVELNAAQSRFISNVSHEL
RTPLFNIKSYVETLHDMGDQLDEEMTREFLATANAETDRLTRLVNDVLDLSRLESDRVWSFEPTEVEAAMEQTLRTYKLN
ADDKGVSLDLAVPPSLPRVRGNYDLLLQVFDNLVGNAVKFSTSGDMVQLRAYLWPDTCPIKADDASSPLPRLRVEVADSG
TGISEEDCRRVFERFYRVENAVHTEAGTGLGLSIVRGILQKHGSDISMVSELGVGTTFWFDLPLEGADEDELIVNAERKA
LALS
>Mature_643_residues
PALTSGWWAEFSLQTKLLAIATLVVSIVMTGLTFFALNGIQTEARMGDTRYARDLGLLLASNVTPLAAQGNDRELARVTE
EFWRSSRSLRYIFYADPEGVIYLGIPISKVDSGNDLLLSRRLELPSDLRQRPQNPLIRQHLTPDGLVTDVFVPMVNGKNY
LGVMALGVNPNEAVLATAALTRNVTVAVFVSIWVLVILGAVFNALTITRPVKELLRGVRSVADGDFGARIALPVGGELGE
LLNGFNTMATQLEAYDEANIEELTAAQVKQQSLIATMADGALLLDPEGQVVLVNPTARRLFRWEGRKLEGQELLRLLPDS
LTMELQEPFDAVRSRERDSAEVRCSINEPNRTLRLVLQAVRDGSGETLKGIAVTVQDLTREVELNAAQSRFISNVSHELR
TPLFNIKSYVETLHDMGDQLDEEMTREFLATANAETDRLTRLVNDVLDLSRLESDRVWSFEPTEVEAAMEQTLRTYKLNA
DDKGVSLDLAVPPSLPRVRGNYDLLLQVFDNLVGNAVKFSTSGDMVQLRAYLWPDTCPIKADDASSPLPRLRVEVADSGT
GISEEDCRRVFERFYRVENAVHTEAGTGLGLSIVRGILQKHGSDISMVSELGVGTTFWFDLPLEGADEDELIVNAERKAL
ALS

Specific function: Member Of The Two-Component Regulatory System Uvry/Bara Involved In The Regulation Of Carbon Metabolism Via The Csra/Csrb Regulatory System. Phosphorylates Uvry, Probably Via A Four-Step Phosphorelay. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=31.6602316602317, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=402, Percent_Identity=28.8557213930348, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788393, Length=265, Percent_Identity=30.5660377358491, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=263, Percent_Identity=28.1368821292776, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788549, Length=402, Percent_Identity=23.8805970149254, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=31.0344827586207, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=30.9623430962343, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1790436, Length=255, Percent_Identity=24.3137254901961, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=30.7377049180328, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=242, Percent_Identity=26.0330578512397, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=25.6302521008403, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789403, Length=231, Percent_Identity=29.4372294372294, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=24.2553191489362, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=27.0916334661355, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790861, Length=253, Percent_Identity=24.5059288537549, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71125; Mature: 70994

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALTSGWWAEFSLQTKLLAIATLVVSIVMTGLTFFALNGIQTEARMGDTRYARDLGLLL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
ASNVTPLAAQGNDRELARVTEEFWRSSRSLRYIFYADPEGVIYLGIPISKVDSGNDLLLS
HCCCCCEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCHHCCCCCCCEEEE
RRLELPSDLRQRPQNPLIRQHLTPDGLVTDVFVPMVNGKNYLGVMALGVNPNEAVLATAA
ECCCCCHHHHHCCCCCHHHHCCCCCCCHHHHHEEEECCCCEEEEEEECCCCCHHHEEHHH
LTRNVTVAVFVSIWVLVILGAVFNALTITRPVKELLRGVRSVADGDFGARIALPVGGELG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHH
ELLNGFNTMATQLEAYDEANIEELTAAQVKQQSLIATMADGALLLDPEGQVVLVNPTARR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECHHHHH
LFRWEGRKLEGQELLRLLPDSLTMELQEPFDAVRSRERDSAEVRCSINEPNRTLRLVLQA
HHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
VRDGSGETLKGIAVTVQDLTREVELNAAQSRFISNVSHELRTPLFNIKSYVETLHDMGDQ
HHCCCCCEEHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
LDEEMTREFLATANAETDRLTRLVNDVLDLSRLESDRVWSFEPTEVEAAMEQTLRTYKLN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECC
ADDKGVSLDLAVPPSLPRVRGNYDLLLQVFDNLVGNAVKFSTSGDMVQLRAYLWPDTCPI
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCCC
KADDASSPLPRLRVEVADSGTGISEEDCRRVFERFYRVENAVHTEAGTGLGLSIVRGILQ
CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KHGSDISMVSELGVGTTFWFDLPLEGADEDELIVNAERKALALS
HCCCCHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCHHEECC
>Mature Secondary Structure 
PALTSGWWAEFSLQTKLLAIATLVVSIVMTGLTFFALNGIQTEARMGDTRYARDLGLLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
ASNVTPLAAQGNDRELARVTEEFWRSSRSLRYIFYADPEGVIYLGIPISKVDSGNDLLLS
HCCCCCEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCHHCCCCCCCEEEE
RRLELPSDLRQRPQNPLIRQHLTPDGLVTDVFVPMVNGKNYLGVMALGVNPNEAVLATAA
ECCCCCHHHHHCCCCCHHHHCCCCCCCHHHHHEEEECCCCEEEEEEECCCCCHHHEEHHH
LTRNVTVAVFVSIWVLVILGAVFNALTITRPVKELLRGVRSVADGDFGARIALPVGGELG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHH
ELLNGFNTMATQLEAYDEANIEELTAAQVKQQSLIATMADGALLLDPEGQVVLVNPTARR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECHHHHH
LFRWEGRKLEGQELLRLLPDSLTMELQEPFDAVRSRERDSAEVRCSINEPNRTLRLVLQA
HHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
VRDGSGETLKGIAVTVQDLTREVELNAAQSRFISNVSHELRTPLFNIKSYVETLHDMGDQ
HHCCCCCEEHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
LDEEMTREFLATANAETDRLTRLVNDVLDLSRLESDRVWSFEPTEVEAAMEQTLRTYKLN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECC
ADDKGVSLDLAVPPSLPRVRGNYDLLLQVFDNLVGNAVKFSTSGDMVQLRAYLWPDTCPI
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCCC
KADDASSPLPRLRVEVADSGTGISEEDCRRVFERFYRVENAVHTEAGTGLGLSIVRGILQ
CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KHGSDISMVSELGVGTTFWFDLPLEGADEDELIVNAERKALALS
HCCCCHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]