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The map label for this gene is ppnK [H]

Identifier: 148242842

GI number: 148242842

Start: 1525546

End: 1526466

Strand: Direct

Name: ppnK [H]

Synonym: SynRCC307_1743

Alternate gene names: 148242842

Gene position: 1525546-1526466 (Clockwise)

Preceding gene: 148242841

Following gene: 148242843

Centisome position: 68.57

GC content: 65.15

Gene sequence:

>921_bases
GTGCCCTGTGCCGGACTGATCGTTAACGACGGCAAGGATCTGGCCATTGAAACGGCCGACCGGATCGAAGCACGCCTCAC
CGAGGCGGGTTGGGATGTGGTGCGCGCCAGCAGCTCCGGCGGAATGGTGGGTTTTGCCAACCCCGATCAGAGCTTGCGGC
TGCTCGGCTATGCGGCCTGCGTGCCGCCTGGCTTCACCTCCGCCATGGATGTGGCGATCGTGCTGGGCGGTGATGGCACG
GTGCTTTCAGCGGCGCGGCAAACGGCACCGGTGGGCGTGCCGATGCTCACGATCAACACAGGCCATTTGGGCTTTCTGGC
TGAAACCTATGTGAGCCACCTGGAAGAGGCCCTCGAGCAGCTGATCAGCCGTGAGTGGACCGTTGAAGAACGCAACCTGG
TTGTGGTGAGCGTGCTGCGCGGCGACCAGCGGCGCTGGGAGGTGCTCTGCCTCAACGAGATGGCGCTGCACCGCGAGCCA
CTCACGAGCATGTGCCATTTCGAGATCGCCATCGGTCGCCATGCGCCGGTAGACATCTCCGCTGACGGGGTGATCCTCTC
GACGCCCACGGGATCGACGGCCTATGCCCTCAGCGCTGGCGGCCCGGTGATCACGCCCGATTGCCCGGTGCTGCAGCTCA
CCCCGATTGCGCCCCACTCGCTGGCTTCACGGGCGCTGGTGTTCAGCGATAGCGAGCCCGTCACGATCTTCCCGGCCACC
CCAGAACGGCTGATGATGGTGGTTGATGGCAGCGCTGGTTGTTATGTCTGGCCGGAGGATCGGGTGCTGATTCGCCGCTG
CGAGCAGGCCGCCCGCTTTGTGCGCCTGGCCGACCACGAATACTTCCGCGTATTGGGCGAGAAGCTGGGCTGGGGCCTGC
CCCATGTGGCCAAGCCGGGCACACTTCCTTTGGCCTCATGA

Upstream 100 bases:

>100_bases
TCGTTTCGCTGCTGCGCTCCGGCCGCAGCGGACGCACTTAACGAAGTCCTAGTAACAGGGAAAGCCCGCCTAAACTCAGG
CACCCACTTGCTCGTGACCG

Downstream 100 bases:

>100_bases
AGCCCACCTTGCTGCTCATCGGTGAGCGCGCCTTGGAATTGCGCGAGCGGCTGGAGGCTTCCGGCTACGACACCGTGGGC
TGGAGCGGCAGCGATGCCGT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPCAGLIVNDGKDLAIETADRIEARLTEAGWDVVRASSSGGMVGFANPDQSLRLLGYAACVPPGFTSAMDVAIVLGGDGT
VLSAARQTAPVGVPMLTINTGHLGFLAETYVSHLEEALEQLISREWTVEERNLVVVSVLRGDQRRWEVLCLNEMALHREP
LTSMCHFEIAIGRHAPVDISADGVILSTPTGSTAYALSAGGPVITPDCPVLQLTPIAPHSLASRALVFSDSEPVTIFPAT
PERLMMVVDGSAGCYVWPEDRVLIRRCEQAARFVRLADHEYFRVLGEKLGWGLPHVAKPGTLPLAS

Sequences:

>Translated_306_residues
MPCAGLIVNDGKDLAIETADRIEARLTEAGWDVVRASSSGGMVGFANPDQSLRLLGYAACVPPGFTSAMDVAIVLGGDGT
VLSAARQTAPVGVPMLTINTGHLGFLAETYVSHLEEALEQLISREWTVEERNLVVVSVLRGDQRRWEVLCLNEMALHREP
LTSMCHFEIAIGRHAPVDISADGVILSTPTGSTAYALSAGGPVITPDCPVLQLTPIAPHSLASRALVFSDSEPVTIFPAT
PERLMMVVDGSAGCYVWPEDRVLIRRCEQAARFVRLADHEYFRVLGEKLGWGLPHVAKPGTLPLAS
>Mature_305_residues
PCAGLIVNDGKDLAIETADRIEARLTEAGWDVVRASSSGGMVGFANPDQSLRLLGYAACVPPGFTSAMDVAIVLGGDGTV
LSAARQTAPVGVPMLTINTGHLGFLAETYVSHLEEALEQLISREWTVEERNLVVVSVLRGDQRRWEVLCLNEMALHREPL
TSMCHFEIAIGRHAPVDISADGVILSTPTGSTAYALSAGGPVITPDCPVLQLTPIAPHSLASRALVFSDSEPVTIFPATP
ERLMMVVDGSAGCYVWPEDRVLIRRCEQAARFVRLADHEYFRVLGEKLGWGLPHVAKPGTLPLAS

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=188, Percent_Identity=31.3829787234043, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788968, Length=223, Percent_Identity=35.4260089686099, Blast_Score=147, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6320794, Length=250, Percent_Identity=28, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325068, Length=169, Percent_Identity=33.7278106508876, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322509, Length=254, Percent_Identity=26.7716535433071, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28573828, Length=184, Percent_Identity=31.5217391304348, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI161077047, Length=184, Percent_Identity=31.5217391304348, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28573826, Length=184, Percent_Identity=31.5217391304348, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573832, Length=184, Percent_Identity=31.5217391304348, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573830, Length=184, Percent_Identity=31.5217391304348, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32803; Mature: 32672

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCAGLIVNDGKDLAIETADRIEARLTEAGWDVVRASSSGGMVGFANPDQSLRLLGYAAC
CCCCCEEEECCCCEEEECHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCEEEEEEEEC
VPPGFTSAMDVAIVLGGDGTVLSAARQTAPVGVPMLTINTGHLGFLAETYVSHLEEALEQ
CCCCCCCCEEEEEEECCCCCEEHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LISREWTVEERNLVVVSVLRGDQRRWEVLCLNEMALHREPLTSMCHFEIAIGRHAPVDIS
HHCCCCCCCCCCEEEEEEECCCCCEEEEEEECHHHHHHCCHHHHEEEEEEECCCCCCEEC
ADGVILSTPTGSTAYALSAGGPVITPDCPVLQLTPIAPHSLASRALVFSDSEPVTIFPAT
CCCEEEECCCCCCEEEEECCCCEECCCCCEEEEECCCCHHHHCEEEEEECCCCEEEEECC
PERLMMVVDGSAGCYVWPEDRVLIRRCEQAARFVRLADHEYFRVLGEKLGWGLPHVAKPG
CCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
TLPLAS
CCCCCC
>Mature Secondary Structure 
PCAGLIVNDGKDLAIETADRIEARLTEAGWDVVRASSSGGMVGFANPDQSLRLLGYAAC
CCCCEEEECCCCEEEECHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCEEEEEEEEC
VPPGFTSAMDVAIVLGGDGTVLSAARQTAPVGVPMLTINTGHLGFLAETYVSHLEEALEQ
CCCCCCCCEEEEEEECCCCCEEHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LISREWTVEERNLVVVSVLRGDQRRWEVLCLNEMALHREPLTSMCHFEIAIGRHAPVDIS
HHCCCCCCCCCCEEEEEEECCCCCEEEEEEECHHHHHHCCHHHHEEEEEEECCCCCCEEC
ADGVILSTPTGSTAYALSAGGPVITPDCPVLQLTPIAPHSLASRALVFSDSEPVTIFPAT
CCCEEEECCCCCCEEEEECCCCEECCCCCEEEEECCCCHHHHCEEEEEECCCCEEEEECC
PERLMMVVDGSAGCYVWPEDRVLIRRCEQAARFVRLADHEYFRVLGEKLGWGLPHVAKPG
CCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
TLPLAS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]