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The map label for this gene is trmD

Identifier: 148242826

GI number: 148242826

Start: 1513255

End: 1513968

Strand: Direct

Name: trmD

Synonym: SynRCC307_1727

Alternate gene names: 148242826

Gene position: 1513255-1513968 (Clockwise)

Preceding gene: 148242825

Following gene: 148242828

Centisome position: 68.01

GC content: 66.95

Gene sequence:

>714_bases
GTGAGCAGCTTCCGGCTGGATGTGGTGAGCCTGGTGCCGGAGGTGTTCGACAGCCTTCGCGGCCTGGGGGTGATCGGTCG
CGCCTTCCATGCCGGCATCGCCGAGCTGCACACCCACAACCCCCGCGATTACGCCACCGATCGCTACCGCAAGGTTGACG
ATGAGCCCTACGGCGGCGGTGCGGGCATGGTGCTTAAACCCGAACCGGTGTTTGCCGCCTTTGAAGCGATCCCGGTGCAG
CCAAGCCGGCGGGTGCTGCTGATGACACCGCAAGGCAAGCCGCTGCAGCAGGCCGACCTACGCCGCTGGGCAACCGATTA
CGAGCAACTGGTCCTGCTCTGCGGCCACTACGAAGGCTTTGATGAGCGCATCCGCAGCCTCGCTGATGAAGAGGTGTCGC
TTGGTGATTTCGTGCTCACCGGCGGCGAACTGCCGGCGATGACGATCATCAATGGCACCGTGCGGCTGCGGCCCGGCACC
GTGGGCACCGCCGATTCCTTGGTGGAGGAAAGCCACAGCGCAGGGCTGCTGGAGCACCCCCATTACACGCGCCCCGCCAC
CTTCCGTGAGATGGACGTGCCGGCGGTGCTGCGCAGCGGCGACCATGGCGCCATTGCCCGCTGGCGCGCCGAGCAGCAGA
AGGAACGCACCCAACTGCGCCGCCCCGATCTCTGGGCCCAATGGCAGGCAGAGCACCCCGGCAACGAGGGCTGA

Upstream 100 bases:

>100_bases
AGCCCAACCTGCGGCTGCGCAACCTGCTGATCTGGAAAGGAGAGCAGCTGCAGGGTTCCCAGTTCTGCTCGGAAATCCGC
CGCGTCAGCAAGCCCGCCTC

Downstream 100 bases:

>100_bases
TCAGCCCTGCTGCTGGAGATTCTTGAGCGCCGTGAGCAAGGCCGCAGGGCTCTGGGGATCCACCATCAACACGCTGCCGC
CTTTGGCCTGGGCCATCTGC

Product: tRNA (guanine-N(1)-)-methyltransferase

Products: NA

Alternate protein names: M1G-methyltransferase; tRNA [GM37] methyltransferase

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSSFRLDVVSLVPEVFDSLRGLGVIGRAFHAGIAELHTHNPRDYATDRYRKVDDEPYGGGAGMVLKPEPVFAAFEAIPVQ
PSRRVLLMTPQGKPLQQADLRRWATDYEQLVLLCGHYEGFDERIRSLADEEVSLGDFVLTGGELPAMTIINGTVRLRPGT
VGTADSLVEESHSAGLLEHPHYTRPATFREMDVPAVLRSGDHGAIARWRAEQQKERTQLRRPDLWAQWQAEHPGNEG

Sequences:

>Translated_237_residues
MSSFRLDVVSLVPEVFDSLRGLGVIGRAFHAGIAELHTHNPRDYATDRYRKVDDEPYGGGAGMVLKPEPVFAAFEAIPVQ
PSRRVLLMTPQGKPLQQADLRRWATDYEQLVLLCGHYEGFDERIRSLADEEVSLGDFVLTGGELPAMTIINGTVRLRPGT
VGTADSLVEESHSAGLLEHPHYTRPATFREMDVPAVLRSGDHGAIARWRAEQQKERTQLRRPDLWAQWQAEHPGNEG
>Mature_236_residues
SSFRLDVVSLVPEVFDSLRGLGVIGRAFHAGIAELHTHNPRDYATDRYRKVDDEPYGGGAGMVLKPEPVFAAFEAIPVQP
SRRVLLMTPQGKPLQQADLRRWATDYEQLVLLCGHYEGFDERIRSLADEEVSLGDFVLTGGELPAMTIINGTVRLRPGTV
GTADSLVEESHSAGLLEHPHYTRPATFREMDVPAVLRSGDHGAIARWRAEQQKERTQLRRPDLWAQWQAEHPGNEG

Specific function: Specifically methylates guanosine-37 in various tRNAs

COG id: COG0336

COG function: function code J; tRNA-(guanine-N1)-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase trmD family

Homologues:

Organism=Escherichia coli, GI1788959, Length=222, Percent_Identity=45.4954954954955, Blast_Score=196, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMD_SYNR3 (A5GUS1)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001227983.1
- ProteinModelPortal:   A5GUS1
- SMR:   A5GUS1
- STRING:   A5GUS1
- GeneID:   5157667
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_1727
- eggNOG:   COG0336
- HOGENOM:   HBG285805
- OMA:   VCGRFEG
- ProtClustDB:   PRK00026
- GO:   GO:0005737
- HAMAP:   MF_00605
- InterPro:   IPR016009
- InterPro:   IPR002649
- InterPro:   IPR023148
- Gene3D:   G3DSA:1.10.1270.20
- PIRSF:   PIRSF000386
- TIGRFAMs:   TIGR00088

Pfam domain/function: PF01746 tRNA_m1G_MT

EC number: =2.1.1.31

Molecular weight: Translated: 26430; Mature: 26299

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: BINDING 115-115

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFRLDVVSLVPEVFDSLRGLGVIGRAFHAGIAELHTHNPRDYATDRYRKVDDEPYGGG
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC
AGMVLKPEPVFAAFEAIPVQPSRRVLLMTPQGKPLQQADLRRWATDYEQLVLLCGHYEGF
CCEEECCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
DERIRSLADEEVSLGDFVLTGGELPAMTIINGTVRLRPGTVGTADSLVEESHSAGLLEHP
HHHHHHHHHCCCCCCCEEEECCCCCEEEEECCEEEECCCCCCCHHHHHHHHHCCCCCCCC
HYTRPATFREMDVPAVLRSGDHGAIARWRAEQQKERTQLRRPDLWAQWQAEHPGNEG
CCCCCCCCHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SSFRLDVVSLVPEVFDSLRGLGVIGRAFHAGIAELHTHNPRDYATDRYRKVDDEPYGGG
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC
AGMVLKPEPVFAAFEAIPVQPSRRVLLMTPQGKPLQQADLRRWATDYEQLVLLCGHYEGF
CCEEECCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
DERIRSLADEEVSLGDFVLTGGELPAMTIINGTVRLRPGTVGTADSLVEESHSAGLLEHP
HHHHHHHHHCCCCCCCEEEECCCCCEEEEECCEEEECCCCCCCHHHHHHHHHCCCCCCCC
HYTRPATFREMDVPAVLRSGDHGAIARWRAEQQKERTQLRRPDLWAQWQAEHPGNEG
CCCCCCCCHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA