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The map label for this gene is era [H]

Identifier: 148242816

GI number: 148242816

Start: 1502490

End: 1503419

Strand: Direct

Name: era [H]

Synonym: SynRCC307_1717

Alternate gene names: 148242816

Gene position: 1502490-1503419 (Clockwise)

Preceding gene: 148242815

Following gene: 148242819

Centisome position: 67.53

GC content: 61.72

Gene sequence:

>930_bases
ATGGTTGAAATCCCCCTGGACTCAATACTGAGCCCCACCCCGGAGGGCTTTCGCTCGGGATTTGTGGCCCTGGTGGGGCG
CCCCAACGTGGGCAAATCCACGCTGCTCAATCAGCTGGTGGGGGAGAAGGTGGCGATCACCTCGCCTGTGGCGCAAACCA
CCCGCAACCGTTTGCGGGCCATCCTCACCACTGAGTGCTCCCAGCTGGTGCTGGTGGACACCCCCGGCATCCACAAACCC
CATCACCTGCTCGGCGAGCGGCTGGTGAAAACCGCGCGCAACAGCATCGGCGAAGTGGATGTGGTGCTGGCGCTGATGGA
TGGCAGTGAACCGATGGGGCGCGGTGATCAATTCGTGCTCGATCTGCTCAAGTCCATCCGCCAACCGGTGGTGATTGGCC
TCAACAAACAAGACCTGATCGCCGAAGAGCAGCGCGAAGAGCTGAACGCCTCCTACAGCGAGGTATTGCCCGATGCACCG
CTCCTGCCCTTTAGTGCACTCACCGGTGATGGCTGCAGCGCCTTGGTGGAAGCCCTGGGCGAACGGCTACCGGAAGGGCC
GATGCTGTACCCGAAAGACACGGTGAGCGATCAGCCTGAGAACCTGCTGCTGGGTGAACTCATCCGCGAGCAGGTGCTGC
ACCACACCCGAGAAGAAGTGCCCCACTCGGTGGCGGTACAAATTGAGCGGGTGGTGGAAGACGGCCCGCGCACGGCGATT
CTGGCCACGGTGATGGTGGAGCGCAGCAGCCAGAAAGGGATCTTGATCGGCCGTAAAGGCTCGATGCTCAAAGAGATCGG
ATCAGGCGCGCGGCTGCAGATGCAAAAGCTGATTGATGGGCCGGTGTATTTGGAGCTGTTTGTGAAGGTGGTGCCCCATT
GGCGCCAGAAACCAGGCCGCTTGGCGGAACTGGGTTACCGGGGCGAGTAA

Upstream 100 bases:

>100_bases
GAATTCCTCGAAGCTGACCTCAGCGGCGACATCGCCGCCACGCTGCACACCGCTGAAAGCAAGCCCAAAGACGGAGGCAA
CGGCAGCGCAGACTGAAGCG

Downstream 100 bases:

>100_bases
GCAGTAAAAAACGCGCCATCGATGGCCTCACCTGGGTGATCAGCTGGCAGGAACTTGTGGATCAGGGTCTGCCCTGTCCT
GGAATCCATCGCATCCTTTT

Product: GTP-binding protein Era-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MVEIPLDSILSPTPEGFRSGFVALVGRPNVGKSTLLNQLVGEKVAITSPVAQTTRNRLRAILTTECSQLVLVDTPGIHKP
HHLLGERLVKTARNSIGEVDVVLALMDGSEPMGRGDQFVLDLLKSIRQPVVIGLNKQDLIAEEQREELNASYSEVLPDAP
LLPFSALTGDGCSALVEALGERLPEGPMLYPKDTVSDQPENLLLGELIREQVLHHTREEVPHSVAVQIERVVEDGPRTAI
LATVMVERSSQKGILIGRKGSMLKEIGSGARLQMQKLIDGPVYLELFVKVVPHWRQKPGRLAELGYRGE

Sequences:

>Translated_309_residues
MVEIPLDSILSPTPEGFRSGFVALVGRPNVGKSTLLNQLVGEKVAITSPVAQTTRNRLRAILTTECSQLVLVDTPGIHKP
HHLLGERLVKTARNSIGEVDVVLALMDGSEPMGRGDQFVLDLLKSIRQPVVIGLNKQDLIAEEQREELNASYSEVLPDAP
LLPFSALTGDGCSALVEALGERLPEGPMLYPKDTVSDQPENLLLGELIREQVLHHTREEVPHSVAVQIERVVEDGPRTAI
LATVMVERSSQKGILIGRKGSMLKEIGSGARLQMQKLIDGPVYLELFVKVVPHWRQKPGRLAELGYRGE
>Mature_309_residues
MVEIPLDSILSPTPEGFRSGFVALVGRPNVGKSTLLNQLVGEKVAITSPVAQTTRNRLRAILTTECSQLVLVDTPGIHKP
HHLLGERLVKTARNSIGEVDVVLALMDGSEPMGRGDQFVLDLLKSIRQPVVIGLNKQDLIAEEQREELNASYSEVLPDAP
LLPFSALTGDGCSALVEALGERLPEGPMLYPKDTVSDQPENLLLGELIREQVLHHTREEVPHSVAVQIERVVEDGPRTAI
LATVMVERSSQKGILIGRKGSMLKEIGSGARLQMQKLIDGPVYLELFVKVVPHWRQKPGRLAELGYRGE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=330, Percent_Identity=27.8787878787879, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1788919, Length=294, Percent_Identity=39.4557823129252, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87082120, Length=179, Percent_Identity=31.2849162011173, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367268, Length=178, Percent_Identity=31.4606741573034, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=178, Percent_Identity=29.2134831460674, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646434, Length=248, Percent_Identity=29.8387096774194, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33807; Mature: 33807

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEIPLDSILSPTPEGFRSGFVALVGRPNVGKSTLLNQLVGEKVAITSPVAQTTRNRLRA
CCCCCHHHHCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHH
ILTTECSQLVLVDTPGIHKPHHLLGERLVKTARNSIGEVDVVLALMDGSEPMGRGDQFVL
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHH
DLLKSIRQPVVIGLNKQDLIAEEQREELNASYSEVLPDAPLLPFSALTGDGCSALVEALG
HHHHHHCCCEEECCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHCCCCCHHHHHHHHH
ERLPEGPMLYPKDTVSDQPENLLLGELIREQVLHHTREEVPHSVAVQIERVVEDGPRTAI
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHH
LATVMVERSSQKGILIGRKGSMLKEIGSGARLQMQKLIDGPVYLELFVKVVPHWRQKPGR
HHHHHHHCCCCCCEEEECCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
LAELGYRGE
HHHCCCCCC
>Mature Secondary Structure
MVEIPLDSILSPTPEGFRSGFVALVGRPNVGKSTLLNQLVGEKVAITSPVAQTTRNRLRA
CCCCCHHHHCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHH
ILTTECSQLVLVDTPGIHKPHHLLGERLVKTARNSIGEVDVVLALMDGSEPMGRGDQFVL
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHH
DLLKSIRQPVVIGLNKQDLIAEEQREELNASYSEVLPDAPLLPFSALTGDGCSALVEALG
HHHHHHCCCEEECCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHCCCCCHHHHHHHHH
ERLPEGPMLYPKDTVSDQPENLLLGELIREQVLHHTREEVPHSVAVQIERVVEDGPRTAI
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHH
LATVMVERSSQKGILIGRKGSMLKEIGSGARLQMQKLIDGPVYLELFVKVVPHWRQKPGR
HHHHHHHCCCCCCEEEECCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
LAELGYRGE
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]