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The map label for this gene is fur [C]

Identifier: 148242720

GI number: 148242720

Start: 1423026

End: 1423409

Strand: Direct

Name: fur [C]

Synonym: SynRCC307_1621

Alternate gene names: 148242720

Gene position: 1423026-1423409 (Clockwise)

Preceding gene: 148242719

Following gene: 148242721

Centisome position: 63.96

GC content: 60.42

Gene sequence:

>384_bases
ATGGCGAAGGGGCTCAGCGACCGCCAGAGACAAATCCTCAGGATCCTTGAGGCGAGCAGCAAGGAGCTGAGCGGCCAAGA
GCTGCACAAATTGGGCAGCGAACTGGGCCAGAGCATGGGCTTGGCCACCGTGTATCGCAACCTGCGGGTGCTGCAACAAG
CAGGGCGAGTTCGCTGCCGTCACCTGCCCAGTGGCGAACTGCTTTACAGCCCACTGGAGCGTGATGTGCACCACCTCACT
TGCCTGGAGTGCGGCACCAGCCAGCCACTAACGAGCTGTCCTGTTGAACAACAAGGGCTCAAGTTGCCCACACCCGAAGG
GTTTGAGCCGCTCTTCCACACCCTGGAAGTCTTTGGCTACTGCGCCAAGTGCAAGCCCGAATGA

Upstream 100 bases:

>100_bases
GGAAGCAAGGGAGAATTCGAGCAACGCCGCCTATTGGGAGGCCAAGCCCAGCTGGGCTGTTGATCACTCCTCTTAAGGTT
GGCGCGTTCTAAGCCGTGTC

Downstream 100 bases:

>100_bases
CTAGCAACAGCAGCGCTATTACGTTGGAAGCCAAAGCAGTCAGCCACTAAGGCGAACACGCAGGCAGCCAACGAGCCGAC
CAATAACGAGAATGATTATC

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric Uptake Regulator Family Protein; Ferric Uptake Regulator Fur Family; FUR Family Transcriptional Regulator; Zinc Uptake Regulator; Ferric-Uptake Regulator; Fur Family Ferric Uptake Regulator; Metal Uptake Regulation Protein; Zinc Uptake Regulator Fur Family; Ferric Uptake Regulator Family; Ferric Uptake Regulator; Fur Family Transcriptional Regulator; Transcriptional Regulator Fur Family Protein; Transcriptional Regulator Fur Family; Metal Uptake Regulator; Ferric Uptake Regulator Furb; Transcriptional Regulator FUR Family; Zinc Uptake Regulation Protein Zur; Ferric Uptake Regulation Protein FurB; Leucine-Rich RepeatFerric Uptake Regulator Family Protein; Fe2+/Zn2+ Uptake Regulation Protein; Ferric Uptake Regulator FurB; Metal Uptake Regulator Ferric Uptake Regulator Protein; Fe(3+) Uptake Regulation Protein; Negative Regulator Of Ferric Iron Uptake

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MAKGLSDRQRQILRILEASSKELSGQELHKLGSELGQSMGLATVYRNLRVLQQAGRVRCRHLPSGELLYSPLERDVHHLT
CLECGTSQPLTSCPVEQQGLKLPTPEGFEPLFHTLEVFGYCAKCKPE

Sequences:

>Translated_127_residues
MAKGLSDRQRQILRILEASSKELSGQELHKLGSELGQSMGLATVYRNLRVLQQAGRVRCRHLPSGELLYSPLERDVHHLT
CLECGTSQPLTSCPVEQQGLKLPTPEGFEPLFHTLEVFGYCAKCKPE
>Mature_126_residues
AKGLSDRQRQILRILEASSKELSGQELHKLGSELGQSMGLATVYRNLRVLQQAGRVRCRHLPSGELLYSPLERDVHHLTC
LECGTSQPLTSCPVEQQGLKLPTPEGFEPLFHTLEVFGYCAKCKPE

Specific function: Acts As A Global Negative Controlling Element, Employing Fe(2+) As A Cofactor To Bind The Operator Of The Repressed Genes. Regulates The Expression Of Several Outer-Membrane Proteins Including The Iron Transport Operon. [C]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786899, Length=115, Percent_Identity=29.5652173913043, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 14173; Mature: 14041

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGLSDRQRQILRILEASSKELSGQELHKLGSELGQSMGLATVYRNLRVLQQAGRVRCR
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLPSGELLYSPLERDVHHLTCLECGTSQPLTSCPVEQQGLKLPTPEGFEPLFHTLEVFGY
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CAKCKPE
HHCCCCC
>Mature Secondary Structure 
AKGLSDRQRQILRILEASSKELSGQELHKLGSELGQSMGLATVYRNLRVLQQAGRVRCR
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLPSGELLYSPLERDVHHLTCLECGTSQPLTSCPVEQQGLKLPTPEGFEPLFHTLEVFGY
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CAKCKPE
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA