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The map label for this gene is actII-2 [H]

Identifier: 148242609

GI number: 148242609

Start: 1343533

End: 1345107

Strand: Direct

Name: actII-2 [H]

Synonym: SynRCC307_1510

Alternate gene names: 148242609

Gene position: 1343533-1345107 (Clockwise)

Preceding gene: 148242608

Following gene: 148242611

Centisome position: 60.39

GC content: 59.81

Gene sequence:

>1575_bases
ATGAAGAAGTGGCTCCCAATCCTGGTGCTGGGGCTCACCCAATTCGTCATGGTGCTGGATGGCACGGTGATGAATGTCTC
CATCACCGACGTGGTGGGTGATCTGGGCACAACCACCAGCAACATGCAGCTGGCCATCGCCACTTTCACGCTGACGATGG
CGGCGTTGATGCTGGCCGGCGCTGGTCTTGGCACGCGCCTTGGACTGCGGCGCACCTTTGTGATTGGCAATGTCATCTAT
GCCATCGGTTCTTTAACCACCGCCTTCGCCCCTGGCTTTGCTGCCCTGTTTATCGGCTGGTCGCTAGTGGAAGGTTTAGG
GGCTGCCCTGGTGGTGCCGGCCATCGCAGCCCTGGCGGCTGTGAATTACAGCGGCCGTGAGCGGGCTATGGCCTATGCCG
TGCTCGGCGGCATTGCTGGAGCTGCTTCAGCCGCAGGCCCCCTGATTGGCGGTTGGATGACCACCTACCTCTCCTGGCGG
TGGGTCTTTGGCTTGGAGACGTTGATCATCTTGCTGTTGGTGCTGCCCCTGCATCGGCGCATCGTTGACCAGCGCCCAAC
GGCGATTCAAGGGAGATTTGATTGGCTTGGGGTGCTGCTTTCAGCGCTCTCGATGGGATTGATCGTGCTGGCTTTGGTCT
CCGCCAGCACCTGGGGCTTGATTCAACCGATCAATCCACCGTTCACGCTGTGGGGATTCTCACCAACAATGCCCATGGTG
GTGGTGGGAGCGATGGTGGCCTGGGGCTTCATCAGTTGGCAGGAGCACTTGCAAACCCATGGCGGCGCCCCCTTGGTGGG
ACTGGATCTGCTGAGCCTGCCCAGCTTGCGTGCTGGCTTGGCTTCGCAACTGGTGCTGTATTTCATCGTGGCGGGAACGT
TCTTTGTGATCCCGCTGTATCTGCAAACCGTGCTCGAGCTCAACGCACTGGAGTCGGGCATTCGCATGCTGCCGATGTCG
GTGTGCCTGTTTTTGGTGGCCCTGATTGGCTCAAAGCTGGCCAGCCGTCGTTCACCACGGCAATTGATCCGCTCGGGTCT
GTTGATCGCCTGCGGGGGCCTGGTGTTGATGATCAGCGCCATTCGCCCTCAAGCCGACAGCATGCTGTTCACCTTGGCCA
TGGCCTCGATCGGCATTGGCATCGGCCTGGCCATCTCCCAGATCGGCAACGTCAACCTTTCGTCCGCTGATCAAACCCGC
AGCACCGAAATCGGTGGCATGCAGGGCACGGCTCAAAACCTTGGTGCCTCCCTCGGTGTTGCCATCGCTGGTACGGCCCT
GTTCATTGCCCTCGGCAACCAGCTCACCACCACGGTCAACAACAATCCTTTGATCAATCCAGTGCTTAAGCAGGCCACTG
AAGCGGCCCAAAAGGAGGGGATTCAGGTGGTGACGCCGGAACTGCTGAACAGTCATTTGCAGAAGGCCGGCGTTCCCAGC
GACCAAATTCAGCTCATCTCAGATGACTACACCAGCAGCAAGTTGCAGGCCCTTCGGCTTGGCCTGGGCTATGTGTTGGT
GGTCGCGTTGCTGGGCCTTCCCCTCACGCGCGGGTTGCCACGTCAACCGCTTTAA

Upstream 100 bases:

>100_bases
GCTGGAGCCATCACCTTGGTCACCGCGCTGTGGTTCACCCCGGAGAGCTGCCGGCTGCCCTTGCAACGTTTATGACAAAG
AAGCGGCCAGTGAGCCTTCC

Downstream 100 bases:

>100_bases
GGCAGCGCACGATCGACGATGTCGCGAATTTCACCGACCCGGTGCATCGACATCACTGTGACATTGATGGGCTTCCTCAA
GGGGCTGCCTGAACGCACAG

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MKKWLPILVLGLTQFVMVLDGTVMNVSITDVVGDLGTTTSNMQLAIATFTLTMAALMLAGAGLGTRLGLRRTFVIGNVIY
AIGSLTTAFAPGFAALFIGWSLVEGLGAALVVPAIAALAAVNYSGRERAMAYAVLGGIAGAASAAGPLIGGWMTTYLSWR
WVFGLETLIILLLVLPLHRRIVDQRPTAIQGRFDWLGVLLSALSMGLIVLALVSASTWGLIQPINPPFTLWGFSPTMPMV
VVGAMVAWGFISWQEHLQTHGGAPLVGLDLLSLPSLRAGLASQLVLYFIVAGTFFVIPLYLQTVLELNALESGIRMLPMS
VCLFLVALIGSKLASRRSPRQLIRSGLLIACGGLVLMISAIRPQADSMLFTLAMASIGIGIGLAISQIGNVNLSSADQTR
STEIGGMQGTAQNLGASLGVAIAGTALFIALGNQLTTTVNNNPLINPVLKQATEAAQKEGIQVVTPELLNSHLQKAGVPS
DQIQLISDDYTSSKLQALRLGLGYVLVVALLGLPLTRGLPRQPL

Sequences:

>Translated_524_residues
MKKWLPILVLGLTQFVMVLDGTVMNVSITDVVGDLGTTTSNMQLAIATFTLTMAALMLAGAGLGTRLGLRRTFVIGNVIY
AIGSLTTAFAPGFAALFIGWSLVEGLGAALVVPAIAALAAVNYSGRERAMAYAVLGGIAGAASAAGPLIGGWMTTYLSWR
WVFGLETLIILLLVLPLHRRIVDQRPTAIQGRFDWLGVLLSALSMGLIVLALVSASTWGLIQPINPPFTLWGFSPTMPMV
VVGAMVAWGFISWQEHLQTHGGAPLVGLDLLSLPSLRAGLASQLVLYFIVAGTFFVIPLYLQTVLELNALESGIRMLPMS
VCLFLVALIGSKLASRRSPRQLIRSGLLIACGGLVLMISAIRPQADSMLFTLAMASIGIGIGLAISQIGNVNLSSADQTR
STEIGGMQGTAQNLGASLGVAIAGTALFIALGNQLTTTVNNNPLINPVLKQATEAAQKEGIQVVTPELLNSHLQKAGVPS
DQIQLISDDYTSSKLQALRLGLGYVLVVALLGLPLTRGLPRQPL
>Mature_524_residues
MKKWLPILVLGLTQFVMVLDGTVMNVSITDVVGDLGTTTSNMQLAIATFTLTMAALMLAGAGLGTRLGLRRTFVIGNVIY
AIGSLTTAFAPGFAALFIGWSLVEGLGAALVVPAIAALAAVNYSGRERAMAYAVLGGIAGAASAAGPLIGGWMTTYLSWR
WVFGLETLIILLLVLPLHRRIVDQRPTAIQGRFDWLGVLLSALSMGLIVLALVSASTWGLIQPINPPFTLWGFSPTMPMV
VVGAMVAWGFISWQEHLQTHGGAPLVGLDLLSLPSLRAGLASQLVLYFIVAGTFFVIPLYLQTVLELNALESGIRMLPMS
VCLFLVALIGSKLASRRSPRQLIRSGLLIACGGLVLMISAIRPQADSMLFTLAMASIGIGIGLAISQIGNVNLSSADQTR
STEIGGMQGTAQNLGASLGVAIAGTALFIALGNQLTTTVNNNPLINPVLKQATEAAQKEGIQVVTPELLNSHLQKAGVPS
DQIQLISDDYTSSKLQALRLGLGYVLVVALLGLPLTRGLPRQPL

Specific function: Promotes the efflux of actinorhodin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=405, Percent_Identity=26.6666666666667, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1790195, Length=430, Percent_Identity=23.7209302325581, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788710, Length=466, Percent_Identity=21.4592274678112, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789042, Length=419, Percent_Identity=21.4797136038186, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788392, Length=418, Percent_Identity=24.6411483253589, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 55095; Mature: 55095

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
>Mature Secondary Structure
MKKWLPILVLGLTQFVMVLDGTVMNVSITDVVGDLGTTTSNMQLAIATFTLTMAALMLAG
CCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHC
AGLGTRLGLRRTFVIGNVIYAIGSLTTAFAPGFAALFIGWSLVEGLGAALVVPAIAALAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNYSGRERAMAYAVLGGIAGAASAAGPLIGGWMTTYLSWRWVFGLETLIILLLVLPLHRR
HCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVDQRPTAIQGRFDWLGVLLSALSMGLIVLALVSASTWGLIQPINPPFTLWGFSPTMPMV
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHH
VVGAMVAWGFISWQEHLQTHGGAPLVGLDLLSLPSLRAGLASQLVLYFIVAGTFFVIPLY
HHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTVLELNALESGIRMLPMSVCLFLVALIGSKLASRRSPRQLIRSGLLIACGGLVLMISA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHH
IRPQADSMLFTLAMASIGIGIGLAISQIGNVNLSSADQTRSTEIGGMQGTAQNLGASLGV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHH
AIAGTALFIALGNQLTTTVNNNPLINPVLKQATEAAQKEGIQVVTPELLNSHLQKAGVPS
HHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCC
DQIQLISDDYTSSKLQALRLGLGYVLVVALLGLPLTRGLPRQPL
HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1878971; 12000953 [H]