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The map label for this gene is aroB [H]

Identifier: 148242518

GI number: 148242518

Start: 1258515

End: 1259636

Strand: Direct

Name: aroB [H]

Synonym: SynRCC307_1419

Alternate gene names: 148242518

Gene position: 1258515-1259636 (Clockwise)

Preceding gene: 148242515

Following gene: 148242521

Centisome position: 56.56

GC content: 63.46

Gene sequence:

>1122_bases
ATGGACAGCGGCGGCGCGATGACAACCGTGACGGTGGAGCTGACGCGCCCCTATGACGTTGTGATTGGCCAGGGCTCACT
GCACCAGCTAGGCGAGCGCCTCAAGCAGCAAGCCATCCGAGCGGGCACCAAAATTTTGGTGGTGTCGAACCCAGTGGTGG
CTGAGCACTACGGCGCCACAGTGATGGGATCGCTCAGCTCCGCTGGCTACGAAGCCGAGCTGCTGGTGATTGAAGCCGGG
GAAGAGCAAAAAACGCCGGCCACCGTGGCTCAGATCCATGACAAGGCCTACGCCATGCAGCTCGAGCGCAGCTCGTTGAT
GCTGGCGCTCGGCGGCGGTGTGGTGGGTGACATGACCGGCTTTGCTGCCGCCACTTGGTTGCGGGGTGTCGCCGTGGTGC
AGGTGCCCACCACCTTGCTGGCGATGGTGGATGCCGCCATTGGCGGCAAAACCGGCGTGAACCACCCCGGCGGGAAAAAC
TTGATCGGCGCCTTTCACCAGCCCAGGCTGGTGATGATTGATTCCGCCACCCTGGGCACGCTGCCGATCCGCGAAGTCCA
CGCCGGCATGGCCGAAGTGATCAAGTACGGCGTGATTGGCGATCCGGTGCTGTTTGAAGCCCTCGAGGCCCACGGGCCGC
TGGACAGCCTCGAGGCCATTGGCTCAACCTTGATGCAACAGATCCTGCGCCGTTCAGCAGCTGCCAAGGCGCGCGTGGTG
GCCCATGACGAGCGGGAAGGAAGCTTGCGGGCGATCCTCAATTACGGCCACACCCTTGGCCATGTGGTGGAAACCCTGAC
GGGTTACGGCACGTACTTGCACGGCGAAGCCGTTGGCATCGGCATGCATGCCGCTGGTCTGCTGAGCCAGCGGCTTGGGC
TATGGAGCGCTGATGAGCAGCAGCGACAGTTGACGTTGCTGAAGCGCTGCGGCCTGCCGTGGCAAGCCCCTGAGCTGAAC
ACCGAAGCGATCCGAACCGCCATCCTGCGCGATAAAAAAGTGCAAAACGGCCGCGTCCGCTTTGTGCTGCCCACCGCCAT
CGGCCAGGTGGTGATCCGCGACGACGTGGACATTGAAGCTGCCGTAGCAGCGCTCAAAGCCACCAGCGGCGTTGAGGCCT
AA

Upstream 100 bases:

>100_bases
CCAAGGAAGCCAGAGGGAGCGGCGCATGCCTTCGGTTCGCTGCCTGCGCATTGTGAGCCAAACAGGCCATACATTCAGAA
GCTCTGGTTCTGTGGTGTCG

Downstream 100 bases:

>100_bases
CAGCAGGGCAACTCAGCGGTCAGGGTTGCGGATCGGAACGCAATGCCAGCGTGCACTTGCCAAGGTTCTTCTTGGCGATC
AACCAGCGCAACCTTGCTGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MDSGGAMTTVTVELTRPYDVVIGQGSLHQLGERLKQQAIRAGTKILVVSNPVVAEHYGATVMGSLSSAGYEAELLVIEAG
EEQKTPATVAQIHDKAYAMQLERSSLMLALGGGVVGDMTGFAAATWLRGVAVVQVPTTLLAMVDAAIGGKTGVNHPGGKN
LIGAFHQPRLVMIDSATLGTLPIREVHAGMAEVIKYGVIGDPVLFEALEAHGPLDSLEAIGSTLMQQILRRSAAAKARVV
AHDEREGSLRAILNYGHTLGHVVETLTGYGTYLHGEAVGIGMHAAGLLSQRLGLWSADEQQRQLTLLKRCGLPWQAPELN
TEAIRTAILRDKKVQNGRVRFVLPTAIGQVVIRDDVDIEAAVAALKATSGVEA

Sequences:

>Translated_373_residues
MDSGGAMTTVTVELTRPYDVVIGQGSLHQLGERLKQQAIRAGTKILVVSNPVVAEHYGATVMGSLSSAGYEAELLVIEAG
EEQKTPATVAQIHDKAYAMQLERSSLMLALGGGVVGDMTGFAAATWLRGVAVVQVPTTLLAMVDAAIGGKTGVNHPGGKN
LIGAFHQPRLVMIDSATLGTLPIREVHAGMAEVIKYGVIGDPVLFEALEAHGPLDSLEAIGSTLMQQILRRSAAAKARVV
AHDEREGSLRAILNYGHTLGHVVETLTGYGTYLHGEAVGIGMHAAGLLSQRLGLWSADEQQRQLTLLKRCGLPWQAPELN
TEAIRTAILRDKKVQNGRVRFVLPTAIGQVVIRDDVDIEAAVAALKATSGVEA
>Mature_373_residues
MDSGGAMTTVTVELTRPYDVVIGQGSLHQLGERLKQQAIRAGTKILVVSNPVVAEHYGATVMGSLSSAGYEAELLVIEAG
EEQKTPATVAQIHDKAYAMQLERSSLMLALGGGVVGDMTGFAAATWLRGVAVVQVPTTLLAMVDAAIGGKTGVNHPGGKN
LIGAFHQPRLVMIDSATLGTLPIREVHAGMAEVIKYGVIGDPVLFEALEAHGPLDSLEAIGSTLMQQILRRSAAAKARVV
AHDEREGSLRAILNYGHTLGHVVETLTGYGTYLHGEAVGIGMHAAGLLSQRLGLWSADEQQRQLTLLKRCGLPWQAPELN
TEAIRTAILRDKKVQNGRVRFVLPTAIGQVVIRDDVDIEAAVAALKATSGVEA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=351, Percent_Identity=45.2991452991453, Blast_Score=278, Evalue=6e-76,
Organism=Saccharomyces cerevisiae, GI6320332, Length=310, Percent_Identity=38.3870967741935, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39404; Mature: 39404

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSGGAMTTVTVELTRPYDVVIGQGSLHQLGERLKQQAIRAGTKILVVSNPVVAEHYGAT
CCCCCEEEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCEEHHHCCCC
VMGSLSSAGYEAELLVIEAGEEQKTPATVAQIHDKAYAMQLERSSLMLALGGGVVGDMTG
EEECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHEECCCCEEEEECCCCHHHHHH
FAAATWLRGVAVVQVPTTLLAMVDAAIGGKTGVNHPGGKNLIGAFHQPRLVMIDSATLGT
HHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCC
LPIREVHAGMAEVIKYGVIGDPVLFEALEAHGPLDSLEAIGSTLMQQILRRSAAAKARVV
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEE
AHDEREGSLRAILNYGHTLGHVVETLTGYGTYLHGEAVGIGMHAAGLLSQRLGLWSADEQ
ECCCCCCHHHHHHHCCHHHHHHHHHHHHCCEEEECCEEEECHHHHHHHHHHCCCCCCCHH
QRQLTLLKRCGLPWQAPELNTEAIRTAILRDKKVQNGRVRFVLPTAIGQVVIRDDVDIEA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCCHHH
AVAALKATSGVEA
HHHHHHHHCCCCC
>Mature Secondary Structure
MDSGGAMTTVTVELTRPYDVVIGQGSLHQLGERLKQQAIRAGTKILVVSNPVVAEHYGAT
CCCCCEEEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCEEHHHCCCC
VMGSLSSAGYEAELLVIEAGEEQKTPATVAQIHDKAYAMQLERSSLMLALGGGVVGDMTG
EEECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHEECCCCEEEEECCCCHHHHHH
FAAATWLRGVAVVQVPTTLLAMVDAAIGGKTGVNHPGGKNLIGAFHQPRLVMIDSATLGT
HHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCC
LPIREVHAGMAEVIKYGVIGDPVLFEALEAHGPLDSLEAIGSTLMQQILRRSAAAKARVV
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEE
AHDEREGSLRAILNYGHTLGHVVETLTGYGTYLHGEAVGIGMHAAGLLSQRLGLWSADEQ
ECCCCCCHHHHHHHCCHHHHHHHHHHHHCCEEEECCEEEECHHHHHHHHHHCCCCCCCHH
QRQLTLLKRCGLPWQAPELNTEAIRTAILRDKKVQNGRVRFVLPTAIGQVVIRDDVDIEA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCCHHH
AVAALKATSGVEA
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]