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The map label for this gene is ahpC [C]

Identifier: 148242337

GI number: 148242337

Start: 1097354

End: 1097953

Strand: Direct

Name: ahpC [C]

Synonym: SynRCC307_1238

Alternate gene names: 148242337

Gene position: 1097354-1097953 (Clockwise)

Preceding gene: 148242335

Following gene: 148242341

Centisome position: 49.32

GC content: 58.83

Gene sequence:

>600_bases
ATGACCACCGGCGTCTTCCGCGTTGGCCTGCAGGCCCCCGATTTCACCGCCACCGCAGTGGTTGACCAAGAGTTCAAGGA
CATCTCCCTATCCCAGTACCGCGGCAAGTACGTGGTGCTGTTCTTTTACCCCCTCGATTTCACCTTTGTCTGCCCAACGG
AGATCACAGCGTTCTCCGATCGCTACGACGCCTTCAAAGCACTGAACACCGAAGTGCTGGGTGTCTCCGTCGACAGCCAG
TTCAGTCACCTGGCCTGGATCCAAACTGAGCGCAAGCAAGGTGGTCTTGGCGACATTGCCTACCCACTGGTTGCTGACCT
CAAAAAGGAGATTGCTAGCGCCTACAACGTCCTCGATGAAGCCGAAGGCGTTGCCCTACGCGGTTTGTTCATCATCAATC
CCGAGGGTGTGGTCCAGCACGCCACCGTCAACAACCTGCCAGTGGGCCGCAACGTGGAGGAAACCCTGCGTGTGCTTCAG
GCCTTCCAGCACGTTGAGGCCAACCCCGACGAGGTCTGCCCCGCCAACTGGACGCCTGGTGAGCGCACCATGAACCCTGA
TCCGGTCGGAAGCAAGGACTTCTTCGCTGCTGTCAACTGA

Upstream 100 bases:

>100_bases
TACCCAGACTAAGCCGCAGGAGCGGGGCAATTGTGATAGCTTAGGGAAGCTTAAACGGAATGAATCCGCTTAAGCAGCTG
TTAATTCTCTGCCTTTCTCC

Downstream 100 bases:

>100_bases
GCAGCGACAGGGTTCCAGCTTCAGCGTCCAAACGAGCCCTCCTGCCCAGCGGGAGGGCTTTATTGGGTCGTCCATGACCC
ACTGGCAGGCCCTGGACAAT

Product: AhpC/TSA family peroxiredoxin

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTTGVFRVGLQAPDFTATAVVDQEFKDISLSQYRGKYVVLFFYPLDFTFVCPTEITAFSDRYDAFKALNTEVLGVSVDSQ
FSHLAWIQTERKQGGLGDIAYPLVADLKKEIASAYNVLDEAEGVALRGLFIINPEGVVQHATVNNLPVGRNVEETLRVLQ
AFQHVEANPDEVCPANWTPGERTMNPDPVGSKDFFAAVN

Sequences:

>Translated_199_residues
MTTGVFRVGLQAPDFTATAVVDQEFKDISLSQYRGKYVVLFFYPLDFTFVCPTEITAFSDRYDAFKALNTEVLGVSVDSQ
FSHLAWIQTERKQGGLGDIAYPLVADLKKEIASAYNVLDEAEGVALRGLFIINPEGVVQHATVNNLPVGRNVEETLRVLQ
AFQHVEANPDEVCPANWTPGERTMNPDPVGSKDFFAAVN
>Mature_198_residues
TTGVFRVGLQAPDFTATAVVDQEFKDISLSQYRGKYVVLFFYPLDFTFVCPTEITAFSDRYDAFKALNTEVLGVSVDSQF
SHLAWIQTERKQGGLGDIAYPLVADLKKEIASAYNVLDEAEGVALRGLFIINPEGVVQHATVNNLPVGRNVEETLRVLQA
FQHVEANPDEVCPANWTPGERTMNPDPVGSKDFFAAVN

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=189, Percent_Identity=62.4338624338624, Blast_Score=251, Evalue=3e-67,
Organism=Homo sapiens, GI5802974, Length=189, Percent_Identity=61.9047619047619, Blast_Score=250, Evalue=7e-67,
Organism=Homo sapiens, GI32189392, Length=199, Percent_Identity=58.7939698492462, Blast_Score=245, Evalue=1e-65,
Organism=Homo sapiens, GI4505591, Length=197, Percent_Identity=58.8832487309645, Blast_Score=243, Evalue=6e-65,
Organism=Homo sapiens, GI32455266, Length=197, Percent_Identity=58.8832487309645, Blast_Score=243, Evalue=6e-65,
Organism=Homo sapiens, GI32455264, Length=197, Percent_Identity=58.8832487309645, Blast_Score=243, Evalue=6e-65,
Organism=Homo sapiens, GI5453549, Length=193, Percent_Identity=55.440414507772, Blast_Score=233, Evalue=6e-62,
Organism=Homo sapiens, GI33188454, Length=113, Percent_Identity=59.2920353982301, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI4758638, Length=191, Percent_Identity=28.2722513089005, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786822, Length=172, Percent_Identity=36.046511627907, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI193204376, Length=188, Percent_Identity=60.1063829787234, Blast_Score=234, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI32565831, Length=188, Percent_Identity=60.1063829787234, Blast_Score=233, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17554494, Length=187, Percent_Identity=55.6149732620321, Blast_Score=223, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI25153706, Length=190, Percent_Identity=25.2631578947368, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323613, Length=195, Percent_Identity=54.3589743589744, Blast_Score=210, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6320661, Length=195, Percent_Identity=52.3076923076923, Blast_Score=204, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6319407, Length=196, Percent_Identity=31.1224489795918, Blast_Score=97, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17738015, Length=192, Percent_Identity=56.7708333333333, Blast_Score=234, Evalue=3e-62,
Organism=Drosophila melanogaster, GI17157991, Length=184, Percent_Identity=60.3260869565217, Blast_Score=234, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24641739, Length=184, Percent_Identity=60.3260869565217, Blast_Score=234, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24656348, Length=188, Percent_Identity=59.0425531914894, Blast_Score=231, Evalue=2e-61,
Organism=Drosophila melanogaster, GI17864676, Length=188, Percent_Identity=59.0425531914894, Blast_Score=231, Evalue=2e-61,
Organism=Drosophila melanogaster, GI21357347, Length=184, Percent_Identity=51.0869565217391, Blast_Score=201, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17975518, Length=189, Percent_Identity=34.9206349206349, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24652436, Length=189, Percent_Identity=34.9206349206349, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24652434, Length=189, Percent_Identity=34.9206349206349, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24581278, Length=191, Percent_Identity=30.3664921465969, Blast_Score=94, Evalue=5e-20,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21980; Mature: 21849

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGVFRVGLQAPDFTATAVVDQEFKDISLSQYRGKYVVLFFYPLDFTFVCPTEITAFSD
CCCCEEEECCCCCCCEEEEEECCCHHCCCHHHCCCCEEEEEEECCCEEEECCCHHHHHHH
RYDAFKALNTEVLGVSVDSQFSHLAWIQTERKQGGLGDIAYPLVADLKKEIASAYNVLDE
HHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AEGVALRGLFIINPEGVVQHATVNNLPVGRNVEETLRVLQAFQHVEANPDEVCPANWTPG
CCCEEEEEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ERTMNPDPVGSKDFFAAVN
CCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
TTGVFRVGLQAPDFTATAVVDQEFKDISLSQYRGKYVVLFFYPLDFTFVCPTEITAFSD
CCCEEEECCCCCCCEEEEEECCCHHCCCHHHCCCCEEEEEEECCCEEEECCCHHHHHHH
RYDAFKALNTEVLGVSVDSQFSHLAWIQTERKQGGLGDIAYPLVADLKKEIASAYNVLDE
HHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AEGVALRGLFIINPEGVVQHATVNNLPVGRNVEETLRVLQAFQHVEANPDEVCPANWTPG
CCCEEEEEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ERTMNPDPVGSKDFFAAVN
CCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]