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The map label for this gene is hemN [C]

Identifier: 148241697

GI number: 148241697

Start: 531937

End: 533169

Strand: Direct

Name: hemN [C]

Synonym: SynRCC307_0598

Alternate gene names: 148241697

Gene position: 531937-533169 (Clockwise)

Preceding gene: 148241691

Following gene: 148241704

Centisome position: 23.91

GC content: 66.67

Gene sequence:

>1233_bases
GTGCCGCTTCCCGCGGGTCGGCGCCCGCCCCGGAGCCTGTATCTCCATATCCCCTTTTGCCATCGGCGCTGTTTTTACTG
CGATTTCCCGGTGGTTCCCCTGGGTGATCAGGCCGATGGCAGCCGCTCCCAGTCGATTGCTGATTACCTCCATTGGTTGC
TGCGCGACCTTGCAGCAGCGCCTGCAGGCCCGCCCCTATCGACCGTTTACATCGGTGGCGGCACCCCATCGATGCTGTCG
CCTGATCAGTTGGCGCAACTGCTGGCGGCGGTTCGTAGCCACTGGGGCTTGGCACCGGGCGCTGAGCTCACCTTGGAAAT
GGATCCGGCCAGCTTTGATCGTCAGCGTCTTGAGGCGGTGCTGGCGCTGGGCATCAATCGCGTCAGCCTCGGCGGGCAGA
GCTTTGACGATGCCGTGCTTGAGCAGCTGGGGCGCCGTCACCGCGCCAACCAACTGCGGGAAGCCTGCAGCTGGTTGCGG
CAGGCCCAGCAGCAGACGCTGCTGCAGAGCTGGAGCTTGGATTTGATCGTCAACCTGCCGCAGCAGAGCTTTGAGGCCTG
GGATTGGGAGTTGAGCCAGGCCTTGGCCCAGGCGCCTCCCCATTTGTCGATTTACGACCTGATCGTGGAGCCCGGCACGG
TGTTTGCCTGGCGCCAAGGCCGCGGAGAGCTGCTGCTGCCGGACGACGATCAGGCCGCCGATCGCTTGCAACACACCCAC
CAGCGGCTGCAGGCGGCGGGATATGGCCATTACGAGGTCAGCAGTTGGGCCCTGCCCGGGCAGGCCAGCCGCCACAACCG
CGTCTATTGGAGTGGGGCGAGCTGGTGGGCCTTGGGGCTCGGGGCCACCTCTGGTGTGGGCACAGAGCGCCTGGCGCGCC
CGCGCACGCGTGATGCCTACAGCGAGTGGGTGCAAGCGGATGCTGGCCGCCAAGGCGATGGCCCAGCCGCCGGCTGGCCT
CCTGTTGAGGATCTGCTGCTAGTGGGTCTGCGCCGCCGTGAGGGGGTGGATCTGGCCTGGCTGCACCAGACGGGGCTTGG
GGGGCTTGAGCGCGCTTGGCTTGAGCGCGTGTTGGCCGGCTGGATTGAGCGCGGTGTGGTGGAGCTCAGCGCTCAGCGTC
TGCGCCTGGTGGCCCCGGAGGGCTTCAGCCTCAGCAATGCGGTGCTGAGTGATTTGCTGGCGGCACTGGAGCGCTCTGAA
CCCCTTGCACCCACTGGCGCAAGGCTTGGCTGA

Upstream 100 bases:

>100_bases
GGAGATCACAAACAACAGCAGGAGCAGAGCTTCCACAATCAGACTGGAGGGACGCGGCGAGCGCGATCTGCGCGAATTTG
CCAGGGAGATTGCCATGAGT

Downstream 100 bases:

>100_bases
ACAGCTCGCGGCCATCCAGCAACGCGGGCGAAAACGGGGGCTGCTGCGGGGTGAGCCCCAGCAGATCAGCGCTGACGCGC
ACTTGGCCATCGCAGCCCTC

Product: oxygen independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MPLPAGRRPPRSLYLHIPFCHRRCFYCDFPVVPLGDQADGSRSQSIADYLHWLLRDLAAAPAGPPLSTVYIGGGTPSMLS
PDQLAQLLAAVRSHWGLAPGAELTLEMDPASFDRQRLEAVLALGINRVSLGGQSFDDAVLEQLGRRHRANQLREACSWLR
QAQQQTLLQSWSLDLIVNLPQQSFEAWDWELSQALAQAPPHLSIYDLIVEPGTVFAWRQGRGELLLPDDDQAADRLQHTH
QRLQAAGYGHYEVSSWALPGQASRHNRVYWSGASWWALGLGATSGVGTERLARPRTRDAYSEWVQADAGRQGDGPAAGWP
PVEDLLLVGLRRREGVDLAWLHQTGLGGLERAWLERVLAGWIERGVVELSAQRLRLVAPEGFSLSNAVLSDLLAALERSE
PLAPTGARLG

Sequences:

>Translated_410_residues
MPLPAGRRPPRSLYLHIPFCHRRCFYCDFPVVPLGDQADGSRSQSIADYLHWLLRDLAAAPAGPPLSTVYIGGGTPSMLS
PDQLAQLLAAVRSHWGLAPGAELTLEMDPASFDRQRLEAVLALGINRVSLGGQSFDDAVLEQLGRRHRANQLREACSWLR
QAQQQTLLQSWSLDLIVNLPQQSFEAWDWELSQALAQAPPHLSIYDLIVEPGTVFAWRQGRGELLLPDDDQAADRLQHTH
QRLQAAGYGHYEVSSWALPGQASRHNRVYWSGASWWALGLGATSGVGTERLARPRTRDAYSEWVQADAGRQGDGPAAGWP
PVEDLLLVGLRRREGVDLAWLHQTGLGGLERAWLERVLAGWIERGVVELSAQRLRLVAPEGFSLSNAVLSDLLAALERSE
PLAPTGARLG
>Mature_409_residues
PLPAGRRPPRSLYLHIPFCHRRCFYCDFPVVPLGDQADGSRSQSIADYLHWLLRDLAAAPAGPPLSTVYIGGGTPSMLSP
DQLAQLLAAVRSHWGLAPGAELTLEMDPASFDRQRLEAVLALGINRVSLGGQSFDDAVLEQLGRRHRANQLREACSWLRQ
AQQQTLLQSWSLDLIVNLPQQSFEAWDWELSQALAQAPPHLSIYDLIVEPGTVFAWRQGRGELLLPDDDQAADRLQHTHQ
RLQAAGYGHYEVSSWALPGQASRHNRVYWSGASWWALGLGATSGVGTERLARPRTRDAYSEWVQADAGRQGDGPAAGWPP
VEDLLLVGLRRREGVDLAWLHQTGLGGLERAWLERVLAGWIERGVVELSAQRLRLVAPEGFSLSNAVLSDLLAALERSEP
LAPTGARLG

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=308, Percent_Identity=35.7142857142857, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1789325, Length=283, Percent_Identity=39.2226148409894, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87082341, Length=289, Percent_Identity=30.1038062283737, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 45138; Mature: 45007

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPAGRRPPRSLYLHIPFCHRRCFYCDFPVVPLGDQADGSRSQSIADYLHWLLRDLAAA
CCCCCCCCCCCEEEEECCHHHCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
PAGPPLSTVYIGGGTPSMLSPDQLAQLLAAVRSHWGLAPGAELTLEMDPASFDRQRLEAV
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
LALGINRVSLGGQSFDDAVLEQLGRRHRANQLREACSWLRQAQQQTLLQSWSLDLIVNLP
HHHCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
QQSFEAWDWELSQALAQAPPHLSIYDLIVEPGTVFAWRQGRGELLLPDDDQAADRLQHTH
HHHHHHHHHHHHHHHHHCCCCCEEEHEEECCCCEEEEECCCCCEECCCCCHHHHHHHHHH
QRLQAAGYGHYEVSSWALPGQASRHNRVYWSGASWWALGLGATSGVGTERLARPRTRDAY
HHHHHCCCCCEECCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHCCCCCHHHH
SEWVQADAGRQGDGPAAGWPPVEDLLLVGLRRREGVDLAWLHQTGLGGLERAWLERVLAG
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
WIERGVVELSAQRLRLVAPEGFSLSNAVLSDLLAALERSEPLAPTGARLG
HHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PLPAGRRPPRSLYLHIPFCHRRCFYCDFPVVPLGDQADGSRSQSIADYLHWLLRDLAAA
CCCCCCCCCCEEEEECCHHHCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
PAGPPLSTVYIGGGTPSMLSPDQLAQLLAAVRSHWGLAPGAELTLEMDPASFDRQRLEAV
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
LALGINRVSLGGQSFDDAVLEQLGRRHRANQLREACSWLRQAQQQTLLQSWSLDLIVNLP
HHHCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
QQSFEAWDWELSQALAQAPPHLSIYDLIVEPGTVFAWRQGRGELLLPDDDQAADRLQHTH
HHHHHHHHHHHHHHHHHCCCCCEEEHEEECCCCEEEEECCCCCEECCCCCHHHHHHHHHH
QRLQAAGYGHYEVSSWALPGQASRHNRVYWSGASWWALGLGATSGVGTERLARPRTRDAY
HHHHHCCCCCEECCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHCCCCCHHHH
SEWVQADAGRQGDGPAAGWPPVEDLLLVGLRRREGVDLAWLHQTGLGGLERAWLERVLAG
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
WIERGVVELSAQRLRLVAPEGFSLSNAVLSDLLAALERSEPLAPTGARLG
HHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]