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The map label for this gene is noeL [H]

Identifier: 148241287

GI number: 148241287

Start: 191233

End: 191439

Strand: Direct

Name: noeL [H]

Synonym: SynRCC307_0188

Alternate gene names: 148241287

Gene position: 191233-191439 (Clockwise)

Preceding gene: 148241273

Following gene: 148241288

Centisome position: 8.6

GC content: 49.76

Gene sequence:

>207_bases
ATGCTTGTTTGCTGGTATTCCTTGGCTAAGCAGACCAAAAGCCAGCTCTCTTATGATCTCAGTGCCCAAGCCCATGTGGC
TGTGAGTTTTGAAAGCGCGGAGTACATCGCCAATTATGATGCCTTAGGAAGCCTACGGATTCTCGGATCGGTACGGATCC
TGTGCCTTACAGAAAAGACTCGGATCTTTCAGGCCAGCACGAGTTGA

Upstream 100 bases:

>100_bases
TTGCACTTCCGTGGCCCCTGTCGAGTCTCGTTGCTGCTGTGCTTGGTGGGTTTGTAAGGCTGCATTCAATGCGCTGCGGG
CTCCTGGGTGGGGCGATTAC

Downstream 100 bases:

>100_bases
CTTTTCAACCATGAGAGTCTGCGCAGTGGAGAAACGTTTGTAACCCGCAAGGTCCGCGCGGTTTAGATCGTGTGGATTCT
GGTTTGGAAGACGCCTACAT

Product: hypothetical protein

Products: NA

Alternate protein names: GDP-D-mannose dehydratase [H]

Number of amino acids: Translated: 68; Mature: 68

Protein sequence:

>68_residues
MLVCWYSLAKQTKSQLSYDLSAQAHVAVSFESAEYIANYDALGSLRILGSVRILCLTEKTRIFQASTS

Sequences:

>Translated_68_residues
MLVCWYSLAKQTKSQLSYDLSAQAHVAVSFESAEYIANYDALGSLRILGSVRILCLTEKTRIFQASTS
>Mature_68_residues
MLVCWYSLAKQTKSQLSYDLSAQAHVAVSFESAEYIANYDALGSLRILGSVRILCLTEKTRIFQASTS

Specific function: Biosynthesis of the slime polysaccharide colanic acid. First of the three steps in the biosynthesis of GDP-fucose from GDP-mannose. [C]

COG id: COG1089

COG function: function code M; GDP-D-mannose dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GDP-mannose 4,6-dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788366, Length=51, Percent_Identity=60.7843137254902, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR006368
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.47 [H]

Molecular weight: Translated: 7549; Mature: 7549

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVCWYSLAKQTKSQLSYDLSAQAHVAVSFESAEYIANYDALGSLRILGSVRILCLTEKT
CEEEEHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEECCCCCCEEEEECCEEEEEEECCC
RIFQASTS
EEEEECCC
>Mature Secondary Structure
MLVCWYSLAKQTKSQLSYDLSAQAHVAVSFESAEYIANYDALGSLRILGSVRILCLTEKT
CEEEEHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEECCCCCCEEEEECCEEEEEEECCC
RIFQASTS
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10065558 [H]