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The map label for this gene is sohB [H]

Identifier: 229259766

GI number: 229259766

Start: 618438

End: 619499

Strand: Direct

Name: sohB [H]

Synonym: VC0395_A0578

Alternate gene names: 229259766

Gene position: 618438-619499 (Clockwise)

Preceding gene: 147674670

Following gene: 147675157

Centisome position: 20.45

GC content: 49.06

Gene sequence:

>1062_bases
TTGGAGTTTTTGTTAGATTACGGCCTGTTTTTGGCCAAGATTGTGACTGTGGTAGTCGCATTGGTCGCAGTACTAGTGAT
AGTAAAATCATTGGGCGGACGCAGTGGTGGTGCCAAAGGGGAGTTGGAAATCACCGATCTGACCGAACAGCATAAAGAGA
CGGTTGAGCGTTTAGAGGCTTATCTGCATGACGAAGCGTTTTTAAAAGCGCGCGATAAAGCGGATAAGAAGAAAGAAAAA
GCTGAGCAGAAAAGTCGTGAAAAGTCGCTTAAGCAAGCGGCGAAAGAAGGTGAATTGGAAAGCAAACGCGATCCGCATCT
GTTTGTGCTTGATTTTCACGGCAGTATTGATGCGAAAGAAGTCGCTTCACTGCGTGAAGAGGTGAGCGCGATTTTGGCGG
TGGCACAAGCGGGTGATGAAGTGCTGCTGCGTTTGGAAACTGGTGGCGGCATGGTGCATGGTTATGGTTTGGCATCATCA
CAACTGGATCGCCTTAAAGCGGCTGGCTTACCGCTGACGATTGCGGTAGATAAAGTTGCAGCTAGCGGCGGTTATATGAT
GGCCTGCATCGCTGATAAAATCGTCAGTGCGCCATTTGCGATTGTCGGATCTATCGGTGTGGTGGCTCAGTTACCAAACT
TCCATAAACTGCTGAAAAAGAACGATATCGAGTTTGAACAGCTCACGGCGGGCGAATACAAGCGCACCTTAACCATGTTT
GGTGAAAACACCGATAAAGCGCGTGAAAAGTTCAAGCAAGAGCTGGAAGAAACACATCAACTGTTCAAAGACTTTATCCG
TGAGCATCGACCCGCGTTGGATCTCGATAAAGTCGCGACAGGTGAACACTGGTTTGGCACGCAGGCCAAAGCTCTGGGGT
TGGTCGATGAGATTCAAACGTCCGATGATTTGATTGTTGCCGCGTGCAAGAGCAAAACCGTACTTCTGCTGCGTTATACG
CAAAAGAAAAAGCTGGCCGATAAACTGGCCGGAGTGGCCGGTGATGCCGCCGACAATGTGTTGCTGAAACTGATCAGTCG
AGGCCAACGTCCCTTGGTTTAA

Upstream 100 bases:

>100_bases
CAAAAATCCAAGGTTAGTCGAGTTGGAAGAGGATTTGCTTTAAGTCTTCGTGACAAGGTGGTTACAATACACCAATTCGT
ATTCAAGAAGGATGAGTCAC

Downstream 100 bases:

>100_bases
GGTTGATTGGTTTACTGTTCGTTGCCGTAATGAAAAAACGCGCTTAGTTTGCTAAGCGCGTTTTTTCATGGTCATCCCTA
AATCATCGCTTTTTGCGCTG

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVERLEAYLHDEAFLKARDKADKKKEK
AEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSIDAKEVASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGLASS
QLDRLKAAGLPLTIAVDKVAASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTLTMF
GENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDEIQTSDDLIVAACKSKTVLLLRYT
QKKKLADKLAGVAGDAADNVLLKLISRGQRPLV

Sequences:

>Translated_353_residues
MEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVERLEAYLHDEAFLKARDKADKKKEK
AEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSIDAKEVASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGLASS
QLDRLKAAGLPLTIAVDKVAASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTLTMF
GENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDEIQTSDDLIVAACKSKTVLLLRYT
QKKKLADKLAGVAGDAADNVLLKLISRGQRPLV
>Mature_353_residues
MEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVERLEAYLHDEAFLKARDKADKKKEK
AEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSIDAKEVASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGLASS
QLDRLKAAGLPLTIAVDKVAASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTLTMF
GENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDEIQTSDDLIVAACKSKTVLLLRYT
QKKKLADKLAGVAGDAADNVLLKLISRGQRPLV

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=353, Percent_Identity=55.8073654390935, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1788064, Length=194, Percent_Identity=26.2886597938144, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 38633; Mature: 38633

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVERLEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
YLHDEAFLKARDKADKKKEKAEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSIDAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHH
VASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGLASSQLDRLKAAGLPLTIAVDKVA
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEHHHH
ASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTLTMF
CCCCEEHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDEIQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCC
SDDLIVAACKSKTVLLLRYTQKKKLADKLAGVAGDAADNVLLKLISRGQRPLV
CCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEFLLDYGLFLAKIVTVVVALVAVLVIVKSLGGRSGGAKGELEITDLTEQHKETVERLEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
YLHDEAFLKARDKADKKKEKAEQKSREKSLKQAAKEGELESKRDPHLFVLDFHGSIDAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHH
VASLREEVSAILAVAQAGDEVLLRLETGGGMVHGYGLASSQLDRLKAAGLPLTIAVDKVA
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEHHHH
ASGGYMMACIADKIVSAPFAIVGSIGVVAQLPNFHKLLKKNDIEFEQLTAGEYKRTLTMF
CCCCEEHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GENTDKAREKFKQELEETHQLFKDFIREHRPALDLDKVATGEHWFGTQAKALGLVDEIQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCC
SDDLIVAACKSKTVLLLRYTQKKKLADKLAGVAGDAADNVLLKLISRGQRPLV
CCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]