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The map label for this gene is prmA

Identifier: 147675659

GI number: 147675659

Start: 2843397

End: 2844284

Strand: Reverse

Name: prmA

Synonym: VC0395_A2687

Alternate gene names: 147675659

Gene position: 2844284-2843397 (Counterclockwise)

Preceding gene: 147673889

Following gene: 147675018

Centisome position: 94.05

GC content: 53.49

Gene sequence:

>888_bases
ATGCCTTGGATTCAAATTAAACTCAATGCGACCAACGACAATGCAGAAGCAATTGGCGATATGCTGATGGAAGAAACTGG
TGCTGTGTCAGTCACTTTCCTCGATGCCAAAGATACCCCTGTATTTGAACCTCTACCGGGCGAAACCCGCCTATGGGGTG
ATACCGATGTCGTCGCACTGTACGAAGCGGATATGGATACCTCGCTGATCCTTCAGCAAATCAAAGCCAGCAACATGCTG
GCTGAAGGTTTTGCTCACAAAGTGGAGCAAGTGGAAGATAAGGACTGGGAACGCGAATGGATGGATAACTTCCACCCAAT
GCAATTTGGCCGTCGCCTCTGGATTTGCCCAAGCTGGCGTGAAGTGCCAGACCCACAAGCGGTGAACGTGATGCTCGACC
CGGGCTTGGCTTTTGGTACCGGCACGCACCCAACCACCGCACTGTGCCTAGAGTGGCTGGATAACCTCGACCTGACTGGC
AAAACCGTGATCGATTTTGGTTGTGGCTCGGGCATTCTGGCGATTGCCGCCATCAAGCTTGGTGCCGCAAAAGTGATCGG
GATTGATATCGATCCACAAGCTCTACTCGCGTCCAAAGACAACGCTGCGCGTAACGGCGTGGAAGATCAAATCGAAGTTT
ATCTGCCAAAAGATCAACCCGAAGGCTTGGTGGCTGACGTGGTGGTCGCGAACATTTTGGCTGGCCCACTGCGTGAGCTT
TCGCCCACCATCAAAGGACTCCTGAAGCCCGGTGGCCAACTGGCCATGTCTGGCATTCTGGATACGCAAGCCGAAAGCGT
GGCGGAATTTTACCGTGACGATCTGGAACTTGACCCAATCGCAGAGAAGAGCGAATGGTGCCGCATTTCTGGCCGCAAGC
TAGGCTAG

Upstream 100 bases:

>100_bases
GTTTTGCTTTTTGTTTTAAATCCGCCCACTTTCTGGCCTGAACATCAGTGGCAAATCTGCTACACTCTGCGCCAATCTAA
ACCCGATGAGATCTTAAGCC

Downstream 100 bases:

>100_bases
ATAAGACTTTGCGGCCTAATTGACTGATAAATCGACTATTTGGCAAAACAATTTGCCAATGCTCAAATATTAGTCTTTTC
AGGCATCAAAAAAATGCGTA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVALYEADMDTSLILQQIKASNML
AEGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWREVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTG
KTVIDFGCGSGILAIAAIKLGAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLREL
SPTIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG

Sequences:

>Translated_295_residues
MPWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVALYEADMDTSLILQQIKASNML
AEGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWREVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTG
KTVIDFGCGSGILAIAAIKLGAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLREL
SPTIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG
>Mature_294_residues
PWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVALYEADMDTSLILQQIKASNMLA
EGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWREVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTGK
TVIDFGCGSGILAIAAIKLGAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLRELS
PTIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=293, Percent_Identity=72.6962457337884, Blast_Score=410, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_VIBC3 (A5F3S3)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F3S3
- SMR:   A5F3S3
- STRING:   A5F3S3
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2687
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EDQDWER
- ProtClustDB:   PRK00517
- BioCyc:   VCHO345073:VC0395_A2687-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32243; Mature: 32112

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVAL
CCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEE
YEADMDTSLILQQIKASNMLAEGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHCCEEEECCCCC
EVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTGKTVIDFGCGSGILAIAAIKL
CCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
GAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLREL
CCEEEEEECCCCHHHEECCCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
SPTIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
PWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVAL
CEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEE
YEADMDTSLILQQIKASNMLAEGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHCCEEEECCCCC
EVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTGKTVIDFGCGSGILAIAAIKL
CCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
GAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLREL
CCEEEEEECCCCHHHEECCCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
SPTIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA