Click here to switch to the map view.

The map label for this gene is aspC [H]

Identifier: 147675573

GI number: 147675573

Start: 929993

End: 931228

Strand: Reverse

Name: aspC [H]

Synonym: VC0395_A0911

Alternate gene names: 147675573

Gene position: 931228-929993 (Counterclockwise)

Preceding gene: 147674157

Following gene: 147674424

Centisome position: 30.79

GC content: 48.22

Gene sequence:

>1236_bases
TTGATGAGTTCAATCATCCCTTCCCACCCTAACTTGACATGGATGTGCTTTATGTTCGAAAAAGTCGTTGCCGCTCCCGC
TGACCCTATCCTAGGTTTAACTGAAGAGTTCAAAAAAGACCCTCGTACCGACAAAATTAACCTCGGTGTAGGTATTTATA
AGAATGAAGCAGGTGAAACCCCGGTTCTCGCTACTGTAAAGAAAGCAGAAGCCGCACTGCTTGAGTCAGAGAAAACCAAA
TCTTATCTCACGATCGAAGGGACAGCTGAGTACGGTTTAGCAGTACAAAAACTGCTGTTCGGCGCGAATTCGGACATAGT
GACACAAAAACTGGCAAAAACAGCGCAAGCCCCTGGTGGCACTGGTGCGCTGCGTGTGGCGGGTGAATTTATTAAGCGTC
AACTGGGCGATGTGAAAGTCTGGATCAGTAACCCAACTTGGGCTAACCATCACGGTGTGTTCAATGCCGCTGGCTTGGAA
ACTACGCAATACGCTTATTATGATGCCAAAGACAAAGATTTTGCCGCTATGCTGGCAGATTTAGAGCAGGCAGAGAAAGG
CGATGTGGTTTTACTGCATGGCTGCTGCCACAATCCAACGGGTATTGACCCAACAGAGCAAGAGTGGGAAGTACTGGCGA
AATTGGTGGCTGACAAAGGCTTACTGCCTCTGTTTGACTTTGCTTACCAAGGCTTTGCTTCAGGTGTGGAAGAAGACGCG
GCTGGCCTACGTATTTTTGCGAAATACAACTCTGAGATTCTGGTTGCCAGCTCTTTCTCAAAGAACTTTGGCTTGTACAA
CGAACGTGTCGGTGCCTTCACGCTGGTTGCACCTTCAACAACCGTTGCAGAAACGGCGTTCTCACAAGTTAAAGCGATTA
TCCGCTCTATCTACTCAAACCCACCAGCTCACGGTGCTGCCGTTGTCACTTATATTCTGAACAACCCAGAATTACGCGCA
GAATGGGAAGCCGAAGTCGCGGAAATGCGTGAACGTATTCAAGAGATGCGCGTACTTTTCGTTAACACATTGAAAGAAGT
GGGTGTAGACGCTGACTTTAGCTTTATCGAGCGTCAAAACGGCATGTTCTCTTTCTCTGGCCTAAGCAAAGAGCAAGTTG
CACGCCTCAAATCAGAGTTGGGTATCTATATCGTCGGCTCTGGCCGCATCAGCGTAGCGGGGATGACCAAATCAAACATG
CTACCCTTGTGCCAAGGCATTGCTGCGGTGATGTAA

Upstream 100 bases:

>100_bases
CCAACTATTCCCAGTTTTTCAGCCAAGTAAAAATTTTTCGATATTTTCTTTCAGGTGCTGTTGTCACCTGAATACGAGGG
AGGTATAAATACGGTAAATT

Downstream 100 bases:

>100_bases
TCGCATCGTCAATGACTCTCTTAAACCGGCTGGAATATGGCCGGTTTTTGTTTTTTTACTGTTCATATACCCAAACTACT
TGGAGTTGCAGGTAGGCGGC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGETPVLATVKKAEAALLESEKTK
SYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGGTGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLE
TTQYAYYDAKDKDFAAMLADLEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEEDA
AGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIYSNPPAHGAAVVTYILNNPELRA
EWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIERQNGMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKSNM
LPLCQGIAAVM

Sequences:

>Translated_411_residues
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGETPVLATVKKAEAALLESEKTK
SYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGGTGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLE
TTQYAYYDAKDKDFAAMLADLEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEEDA
AGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIYSNPPAHGAAVVTYILNNPELRA
EWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIERQNGMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKSNM
LPLCQGIAAVM
>Mature_411_residues
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGETPVLATVKKAEAALLESEKTK
SYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGGTGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLE
TTQYAYYDAKDKDFAAMLADLEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEEDA
AGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIYSNPPAHGAAVVTYILNNPELRA
EWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIERQNGMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKSNM
LPLCQGIAAVM

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=393, Percent_Identity=43.2569974554707, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI4504067, Length=393, Percent_Identity=41.2213740458015, Blast_Score=298, Evalue=6e-81,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=27.6762402088773, Blast_Score=149, Evalue=5e-36,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=62.3737373737374, Blast_Score=527, Evalue=1e-151,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=43.8287153652393, Blast_Score=341, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI71981858, Length=413, Percent_Identity=41.6464891041162, Blast_Score=343, Evalue=7e-95,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=40.5063291139241, Blast_Score=314, Evalue=5e-86,
Organism=Caenorhabditis elegans, GI17569539, Length=398, Percent_Identity=36.1809045226131, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17569537, Length=378, Percent_Identity=31.2169312169312, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI25147136, Length=218, Percent_Identity=38.0733944954128, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=32.6996197718631, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=36.2962962962963, Blast_Score=281, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6322743, Length=428, Percent_Identity=33.1775700934579, Blast_Score=249, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=41.8546365914787, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=41.8546365914787, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24580972, Length=403, Percent_Identity=40.9429280397022, Blast_Score=314, Evalue=8e-86,
Organism=Drosophila melanogaster, GI24580970, Length=403, Percent_Identity=40.9429280397022, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI19920542, Length=390, Percent_Identity=41.2820512820513, Blast_Score=310, Evalue=1e-84,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44727; Mature: 44727

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGET
CCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCCCC
PVLATVKKAEAALLESEKTKSYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGG
CCEEHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
TGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLETTQYAYYDAKDKDFAAMLAD
CCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEECCCCCCCEEEEECCCCCHHHHHHHH
LEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEEDA
HHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
AGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIYSN
CCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCC
PPAHGAAVVTYILNNPELRAEWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIERQN
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
GMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKSNMLPLCQGIAAVM
CEEEECCCCHHHHHHHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGET
CCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCCCC
PVLATVKKAEAALLESEKTKSYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGG
CCEEHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
TGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLETTQYAYYDAKDKDFAAMLAD
CCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEECCCCCCCEEEEECCCCCHHHHHHHH
LEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEEDA
HHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
AGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIYSN
CCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCC
PPAHGAAVVTYILNNPELRAEWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIERQN
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
GMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKSNMLPLCQGIAAVM
CEEEECCCCHHHHHHHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]