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The map label for this gene is ace [H]

Identifier: 147675552

GI number: 147675552

Start: 1117239

End: 1117532

Strand: Reverse

Name: ace [H]

Synonym: VC0395_A1062

Alternate gene names: 147675552

Gene position: 1117532-1117239 (Counterclockwise)

Preceding gene: 147673104

Following gene: 147674144

Centisome position: 36.95

GC content: 45.24

Gene sequence:

>294_bases
GTGATGCTTATGATGGACCCCCTTTATGACTGGCTAATTGATGGCTTTACGTGGCTTGTGATCAAGCTCGGTATTATGTG
GATTGAGAGCAAGATTTTTGTCATCCAATTCTTCTGGGAGATGTCCCAGAAAGTGATTGATATGTTTACCATCTATCCGC
TTATCCAACAGGCTATCGATATGCTGTCTCCTCAATACAGCGGCTTTCTGTTCTTTTTAGGGTTAGACCAAGCGCTGGCT
ATCGTGCTTCAGGCTTTGATGACCCGTTTCGCCCTGCGAGCGTTAAACCTATGA

Upstream 100 bases:

>100_bases
TCTGTTTTGACTTCTCCCTCTTTTCTGAAAACCTGCACATCATCCGCATGATAGTGCTCGCGATGGCGTACATTCTGGCC
GCCATGCTCATTTTGTTTAG

Downstream 100 bases:

>100_bases
GTATCTTTATTCATCACGGCGCGCCAGGCTCTTATAAAACGTCCGGGGCATTATGGCTTCGTCTGCTGCCGGCGATTAAG
TCAGGCCGTCACATCATCAC

Product: accessory cholera enterotoxin

Products: NA

Alternate protein names: Ace [H]

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MMLMMDPLYDWLIDGFTWLVIKLGIMWIESKIFVIQFFWEMSQKVIDMFTIYPLIQQAIDMLSPQYSGFLFFLGLDQALA
IVLQALMTRFALRALNL

Sequences:

>Translated_97_residues
MMLMMDPLYDWLIDGFTWLVIKLGIMWIESKIFVIQFFWEMSQKVIDMFTIYPLIQQAIDMLSPQYSGFLFFLGLDQALA
IVLQALMTRFALRALNL
>Mature_97_residues
MMLMMDPLYDWLIDGFTWLVIKLGIMWIESKIFVIQFFWEMSQKVIDMFTIYPLIQQAIDMLSPQYSGFLFFLGLDQALA
IVLQALMTRFALRALNL

Specific function: Increases short-circuit current in rabbit ileal tissue mounted in Ussing chambers, by increasing the potential difference. Cultures of V.cholerae containing the cloned ace gene cause fluid secretion in ligated rabbit ileal loops [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020495
- InterPro:   IPR019670
- ProDom:   PD065768 [H]

Pfam domain/function: PF10734 DUF2523 [H]

EC number: NA

Molecular weight: Translated: 11464; Mature: 11464

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
9.3 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
9.3 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLMMDPLYDWLIDGFTWLVIKLGIMWIESKIFVIQFFWEMSQKVIDMFTIYPLIQQAID
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLSPQYSGFLFFLGLDQALAIVLQALMTRFALRALNL
HHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMLMMDPLYDWLIDGFTWLVIKLGIMWIESKIFVIQFFWEMSQKVIDMFTIYPLIQQAID
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLSPQYSGFLFFLGLDQALAIVLQALMTRFALRALNL
HHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8389476; 10952301 [H]