| Definition | Vibrio cholerae O395 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_009457 |
| Length | 3,024,069 |
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The map label for this gene is polB [H]
Identifier: 147675373
GI number: 147675373
Start: 846306
End: 848669
Strand: Reverse
Name: polB [H]
Synonym: VC0395_A0831
Alternate gene names: 147675373
Gene position: 848669-846306 (Counterclockwise)
Preceding gene: 147675571
Following gene: 147674461
Centisome position: 28.06
GC content: 48.77
Gene sequence:
>2364_bases TTGAAGATTGAACAAGGGTTTGTATTAACGCGTCACGCTCGTGATGTGGCTGGACAAACCCAAATTGAACTTTGGCTCGC GACACCTTCAGGCCCAACGCAACTTACCATACGCGGTGAGCGTCCGGTTTTTTTTATTGAACAATCGGCTAGCCAAGAAG TGATGCGAATTGCCGCAGAATTATCAATAACGCCCTCATTAGCGCCTCTGTCATTACGTAGCTTTGCAGGCCAACCCCTC GCCGCTTGTTACTGCAATACGATTCGCGATAGCCAAATCTTAGCCGAGAAACTCGCTCAAGCGGACATGTTGATCTTAGA GGCGGATATTCGTTTGGCTGACCGTTTTCTGATGGAACGCTTTATCCAAGGCAGCATCGAATTTACTGGTCAGATCACCG ATTTCGGCCATTATCGCCAAGTTCAGCAAGCCAAATGTCGCCAAGGTGATTACCTACCGACGCTGAATATGGTATCGCTA GACATCGAATGCTCCGAAAAAGGGCTACTCTACTCGATTGGTTTGGATAGCCCGATGGACAGCCGAGTGATTATGATAGG TCAACCAGAACCCGCGGAAACGCCGATTCAATGGGTCGAGGATGAATACCAGTTACTCAAAGCGCTCATTGCATGGTTTG AGCAGTTTGATCCTGATGTGATTATTGGTTGGAGTGTAGTGGATTTCGATTTCCGGCTGCTGCACAAACGCGCGGAGTTC CACAAACTGAAACTCACTATTGGACGAGCTCAGCAACCGAGCTTCTTCCGCACGGCGAGCCAAACTCAGCAAGGCTTTAT CAGTATTCCCGGGCGTGTGGTGCTCGATGGTATCGATACGTTAAAAACCGCGACTTACCATTTTCGTTCATGGTCTTTGG AGTCGGTCTCGCAAGAGCTGCTCGGCGAAGGGAAAGCGATCCATAACGTGCATGATCGGATGGATGAAATTAACCAGATG TTTCGCCACGATAAGCCCTCACTCGCTCGCTACAACCTGCAAGACTGCGTATTAGTGAATAAGATTTTTGCGGCCACTCA TCTGCTCGATTTCGCCATTCAGCGTTCACGTTTAACGGGTGTCGAGTTAGATCGCATTGGTGGCTCCGTGGCCGCATTCA CCAATCTCTATCTGCCACAACTGCACCGCGCAGGGTATGTCGCTCCCAATTTGCAGCCAGAAAACTGGGTTGCCAGCCCT GGCGGTTATGTGATGGACTCGATTCCGGGGCTGTATGACTCGGTACTCGTGCTCGACTTTAAAAGCCTCTACCCTTCGAT TATTCGCTCGTTTTTGATTGATCCGCTTGGATTGATTGAAGGATTAAAGCTACCGATAGGCAAACAAGCTGATCACGCGG TTCCGGGCTTTCGCGGTGGTCAATTTCATCGTACCAAACACTTTTTGCCTGAGATGATCGAAAAGCTATGGGCAGCGCGC GATGAAGCCAAACGCAACCAAGAAAAGGCCTTTTCGCAAGCGATCAAAATCATCATGAACTCGTTTTATGGCGTACTCGG ATCATCAGGCTGCCGCTTTTTCGATGCGCGATTGGCATCGAGCATTACCATGCGCGGCCATGAAATCATGATCCAAACAA AACGGTTGATTGAAGCGCGCGGCTATCAAGTAATTTATGGCGATACCGATTCAACGTTTGTCGCACTCGGTGGGCAATAC TCTCAGCAAGAAGCCGACGCGATTGGTAATGCTTTGGTGAGTGAAATCAACCAATGGTGGACAGAGCATTTAAAGCAAGA ATATGCCCTTGCTTCGATTCTTGAACTCGAATACGAAACCCACTATCGCCGTTTTTTAATGCCGACCATTCGCGGTTCAG AAACGGGCTCCAAAAAACGCTATGCGGGTTTAAAAGGGGATGGTGATAATGAACAACTGATTTTTAAAGGTTTGGAAAGC GCACGCACCGATTGGACGCCGCTCGCGCAACGGTTTCAACATCAGCTGTATCAATTGATTTTCCACGGCCAAGACCCAGA ATCCTATATTCGCACTATTGTAGAACAGACATTGGCAGGCCAATTGGATGAACAATTGGTGTATCAAAAGCGTTTACGCC GACGGTTACATGAGTACCAAAAGAATGTGCCGCCGCAAGTACGCGCAGCCAGAATGGCGGATGACATTAATGCCAAACTC GGGCGGCCTCTACAGTATCAGTATCGCGGCAGCATTGAATATTTGATCACCGTGAATGGACCAGAGCCGAAAGAGTATTC CAAAAGTCCGATGGATTATCAGCACTACATCGACAAGCAACTCAAACCGGTGGCAGACGCGATTTTGCCTTTCATCGGCA AGCAATTTGACGAGCTTATTGCACCTCAGCTGGGGTTGTTTTGA
Upstream 100 bases:
>100_bases CCACTCCTGCTTGTGATGCCACAATGCGATGTAATCAGCTTCACTATCAGTATAATGTGCCAGCGCAAAAATGTATGAGT GTTGAAAAAGGTGGGCCAGA
Downstream 100 bases:
>100_bases GCATATTACGTTCTTGCACGAATTCCACCAAATGTTCACGAGTGAGAGATTTACTGTAAAACCAGCCTTGTACTGAGAAA GGGTATTCATCTCCCATCGC
Product: DNA polymerase II
Products: NA
Alternate protein names: Pol II [H]
Number of amino acids: Translated: 787; Mature: 787
Protein sequence:
>787_residues MKIEQGFVLTRHARDVAGQTQIELWLATPSGPTQLTIRGERPVFFIEQSASQEVMRIAAELSITPSLAPLSLRSFAGQPL AACYCNTIRDSQILAEKLAQADMLILEADIRLADRFLMERFIQGSIEFTGQITDFGHYRQVQQAKCRQGDYLPTLNMVSL DIECSEKGLLYSIGLDSPMDSRVIMIGQPEPAETPIQWVEDEYQLLKALIAWFEQFDPDVIIGWSVVDFDFRLLHKRAEF HKLKLTIGRAQQPSFFRTASQTQQGFISIPGRVVLDGIDTLKTATYHFRSWSLESVSQELLGEGKAIHNVHDRMDEINQM FRHDKPSLARYNLQDCVLVNKIFAATHLLDFAIQRSRLTGVELDRIGGSVAAFTNLYLPQLHRAGYVAPNLQPENWVASP GGYVMDSIPGLYDSVLVLDFKSLYPSIIRSFLIDPLGLIEGLKLPIGKQADHAVPGFRGGQFHRTKHFLPEMIEKLWAAR DEAKRNQEKAFSQAIKIIMNSFYGVLGSSGCRFFDARLASSITMRGHEIMIQTKRLIEARGYQVIYGDTDSTFVALGGQY SQQEADAIGNALVSEINQWWTEHLKQEYALASILELEYETHYRRFLMPTIRGSETGSKKRYAGLKGDGDNEQLIFKGLES ARTDWTPLAQRFQHQLYQLIFHGQDPESYIRTIVEQTLAGQLDEQLVYQKRLRRRLHEYQKNVPPQVRAARMADDINAKL GRPLQYQYRGSIEYLITVNGPEPKEYSKSPMDYQHYIDKQLKPVADAILPFIGKQFDELIAPQLGLF
Sequences:
>Translated_787_residues MKIEQGFVLTRHARDVAGQTQIELWLATPSGPTQLTIRGERPVFFIEQSASQEVMRIAAELSITPSLAPLSLRSFAGQPL AACYCNTIRDSQILAEKLAQADMLILEADIRLADRFLMERFIQGSIEFTGQITDFGHYRQVQQAKCRQGDYLPTLNMVSL DIECSEKGLLYSIGLDSPMDSRVIMIGQPEPAETPIQWVEDEYQLLKALIAWFEQFDPDVIIGWSVVDFDFRLLHKRAEF HKLKLTIGRAQQPSFFRTASQTQQGFISIPGRVVLDGIDTLKTATYHFRSWSLESVSQELLGEGKAIHNVHDRMDEINQM FRHDKPSLARYNLQDCVLVNKIFAATHLLDFAIQRSRLTGVELDRIGGSVAAFTNLYLPQLHRAGYVAPNLQPENWVASP GGYVMDSIPGLYDSVLVLDFKSLYPSIIRSFLIDPLGLIEGLKLPIGKQADHAVPGFRGGQFHRTKHFLPEMIEKLWAAR DEAKRNQEKAFSQAIKIIMNSFYGVLGSSGCRFFDARLASSITMRGHEIMIQTKRLIEARGYQVIYGDTDSTFVALGGQY SQQEADAIGNALVSEINQWWTEHLKQEYALASILELEYETHYRRFLMPTIRGSETGSKKRYAGLKGDGDNEQLIFKGLES ARTDWTPLAQRFQHQLYQLIFHGQDPESYIRTIVEQTLAGQLDEQLVYQKRLRRRLHEYQKNVPPQVRAARMADDINAKL GRPLQYQYRGSIEYLITVNGPEPKEYSKSPMDYQHYIDKQLKPVADAILPFIGKQFDELIAPQLGLF >Mature_787_residues MKIEQGFVLTRHARDVAGQTQIELWLATPSGPTQLTIRGERPVFFIEQSASQEVMRIAAELSITPSLAPLSLRSFAGQPL AACYCNTIRDSQILAEKLAQADMLILEADIRLADRFLMERFIQGSIEFTGQITDFGHYRQVQQAKCRQGDYLPTLNMVSL DIECSEKGLLYSIGLDSPMDSRVIMIGQPEPAETPIQWVEDEYQLLKALIAWFEQFDPDVIIGWSVVDFDFRLLHKRAEF HKLKLTIGRAQQPSFFRTASQTQQGFISIPGRVVLDGIDTLKTATYHFRSWSLESVSQELLGEGKAIHNVHDRMDEINQM FRHDKPSLARYNLQDCVLVNKIFAATHLLDFAIQRSRLTGVELDRIGGSVAAFTNLYLPQLHRAGYVAPNLQPENWVASP GGYVMDSIPGLYDSVLVLDFKSLYPSIIRSFLIDPLGLIEGLKLPIGKQADHAVPGFRGGQFHRTKHFLPEMIEKLWAAR DEAKRNQEKAFSQAIKIIMNSFYGVLGSSGCRFFDARLASSITMRGHEIMIQTKRLIEARGYQVIYGDTDSTFVALGGQY SQQEADAIGNALVSEINQWWTEHLKQEYALASILELEYETHYRRFLMPTIRGSETGSKKRYAGLKGDGDNEQLIFKGLES ARTDWTPLAQRFQHQLYQLIFHGQDPESYIRTIVEQTLAGQLDEQLVYQKRLRRRLHEYQKNVPPQVRAARMADDINAKL GRPLQYQYRGSIEYLITVNGPEPKEYSKSPMDYQHYIDKQLKPVADAILPFIGKQFDELIAPQLGLF
Specific function: Thought to be involved in DNA repair and/or mutagenesis [H]
COG id: COG0417
COG function: function code L; DNA polymerase elongation subunit (family B)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DNA polymerase type-B family [H]
Homologues:
Organism=Homo sapiens, GI156616275, Length=703, Percent_Identity=28.1650071123755, Blast_Score=170, Evalue=6e-42, Organism=Homo sapiens, GI106507301, Length=680, Percent_Identity=24.2647058823529, Blast_Score=127, Evalue=4e-29, Organism=Escherichia coli, GI1786246, Length=794, Percent_Identity=52.3929471032746, Blast_Score=815, Evalue=0.0, Organism=Caenorhabditis elegans, GI17559488, Length=703, Percent_Identity=26.6002844950213, Blast_Score=154, Evalue=2e-37, Organism=Caenorhabditis elegans, GI32565317, Length=659, Percent_Identity=25.948406676783, Blast_Score=130, Evalue=2e-30, Organism=Saccharomyces cerevisiae, GI6320101, Length=704, Percent_Identity=25.4261363636364, Blast_Score=132, Evalue=2e-31, Organism=Saccharomyces cerevisiae, GI6324227, Length=574, Percent_Identity=25.2613240418118, Blast_Score=121, Evalue=4e-28, Organism=Saccharomyces cerevisiae, GI6324067, Length=276, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24664937, Length=704, Percent_Identity=24.1477272727273, Blast_Score=136, Evalue=5e-32, Organism=Drosophila melanogaster, GI24648780, Length=652, Percent_Identity=23.6196319018405, Blast_Score=117, Evalue=3e-26,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006172 - InterPro: IPR017964 - InterPro: IPR006133 - InterPro: IPR006134 - InterPro: IPR023211 - InterPro: IPR012337 [H]
Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 89496; Mature: 89496
Theoretical pI: Translated: 6.68; Mature: 6.68
Prosite motif: PS00116 DNA_POLYMERASE_B
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKIEQGFVLTRHARDVAGQTQIELWLATPSGPTQLTIRGERPVFFIEQSASQEVMRIAAE CCCCCCCEEEEHHHHCCCCEEEEEEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHH LSITPSLAPLSLRSFAGQPLAACYCNTIRDSQILAEKLAQADMLILEADIRLADRFLMER HCCCCCCCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHH FIQGSIEFTGQITDFGHYRQVQQAKCRQGDYLPTLNMVSLDIECSEKGLLYSIGLDSPMD HHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCC SRVIMIGQPEPAETPIQWVEDEYQLLKALIAWFEQFDPDVIIGWSVVDFDFRLLHKRAEF CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHH HKLKLTIGRAQQPSFFRTASQTQQGFISIPGRVVLDGIDTLKTATYHFRSWSLESVSQEL HEEEEEECCCCCCHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHHH LGEGKAIHNVHDRMDEINQMFRHDKPSLARYNLQDCVLVNKIFAATHLLDFAIQRSRLTG HHCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC VELDRIGGSVAAFTNLYLPQLHRAGYVAPNLQPENWVASPGGYVMDSIPGLYDSVLVLDF CCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHH KSLYPSIIRSFLIDPLGLIEGLKLPIGKQADHAVPGFRGGQFHRTKHFLPEMIEKLWAAR HHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH DEAKRNQEKAFSQAIKIIMNSFYGVLGSSGCRFFDARLASSITMRGHEIMIQTKRLIEAR HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHC GYQVIYGDTDSTFVALGGQYSQQEADAIGNALVSEINQWWTEHLKQEYALASILELEYET CCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HYRRFLMPTIRGSETGSKKRYAGLKGDGDNEQLIFKGLESARTDWTPLAQRFQHQLYQLI HHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH FHGQDPESYIRTIVEQTLAGQLDEQLVYQKRLRRRLHEYQKNVPPQVRAARMADDINAKL HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH GRPLQYQYRGSIEYLITVNGPEPKEYSKSPMDYQHYIDKQLKPVADAILPFIGKQFDELI CCCEEEEECCCEEEEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH APQLGLF CCCCCCC >Mature Secondary Structure MKIEQGFVLTRHARDVAGQTQIELWLATPSGPTQLTIRGERPVFFIEQSASQEVMRIAAE CCCCCCCEEEEHHHHCCCCEEEEEEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHH LSITPSLAPLSLRSFAGQPLAACYCNTIRDSQILAEKLAQADMLILEADIRLADRFLMER HCCCCCCCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHH FIQGSIEFTGQITDFGHYRQVQQAKCRQGDYLPTLNMVSLDIECSEKGLLYSIGLDSPMD HHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCC SRVIMIGQPEPAETPIQWVEDEYQLLKALIAWFEQFDPDVIIGWSVVDFDFRLLHKRAEF CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHH HKLKLTIGRAQQPSFFRTASQTQQGFISIPGRVVLDGIDTLKTATYHFRSWSLESVSQEL HEEEEEECCCCCCHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHHH LGEGKAIHNVHDRMDEINQMFRHDKPSLARYNLQDCVLVNKIFAATHLLDFAIQRSRLTG HHCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC VELDRIGGSVAAFTNLYLPQLHRAGYVAPNLQPENWVASPGGYVMDSIPGLYDSVLVLDF CCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHH KSLYPSIIRSFLIDPLGLIEGLKLPIGKQADHAVPGFRGGQFHRTKHFLPEMIEKLWAAR HHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH DEAKRNQEKAFSQAIKIIMNSFYGVLGSSGCRFFDARLASSITMRGHEIMIQTKRLIEAR HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHC GYQVIYGDTDSTFVALGGQYSQQEADAIGNALVSEINQWWTEHLKQEYALASILELEYET CCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HYRRFLMPTIRGSETGSKKRYAGLKGDGDNEQLIFKGLESARTDWTPLAQRFQHQLYQLI HHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH FHGQDPESYIRTIVEQTLAGQLDEQLVYQKRLRRRLHEYQKNVPPQVRAARMADDINAKL HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH GRPLQYQYRGSIEYLITVNGPEPKEYSKSPMDYQHYIDKQLKPVADAILPFIGKQFDELI CCCEEEEECCCEEEEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH APQLGLF CCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2034216; 2261080; 1630901; 9278503; 2217198; 9079692 [H]