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The map label for this gene is mukF

Identifier: 147675329

GI number: 147675329

Start: 1407465

End: 1408802

Strand: Reverse

Name: mukF

Synonym: VC0395_A1319

Alternate gene names: 147675329

Gene position: 1408802-1407465 (Counterclockwise)

Preceding gene: 147674195

Following gene: 147675372

Centisome position: 46.59

GC content: 50.45

Gene sequence:

>1338_bases
ATGAGTGAGTTTACTCAGGATACTGTGCAAAAGCCCATCGACGAACTCGTCACTTGGGTAAAACAGTATGACTTCTCATT
GAATCTGCCTACTGAGCGGCTGGCATTTTTGCTCGCGATTGCTGTGCTTAGTAATGAAAGATTTGATGAAGAGCTCGGAG
AAGGGGAACTTCACGATGCATTCGCGATAGTGACGCGCTTGTTTGCAGAATCGGGAGAAGCCTCAGCCTTTCGGGCTAAC
AATGCGATTAATGATCTGGTCAAGCAGCGCTTACTAAGCCGTTTTACCAGCGAAATGACGGAAGGTGCCAGCATCTACCG
TTTGACTCCGTTGGCGATCGGCATTACCGATTACTATGTGCGTCATCGCGAATTTTCCAAACTCAAACTATCCATCCAAC
TCTCTATGGTGGCGGATGAGATGGCGAAAGCCGTGGAATCTGCGCAGCAGGGTGGCAGTGTCGCTCATTGGCGCAAAAAC
GTGTTTGGCGTGCTCAAATATTCGGTGAGTGAAATCTTCGATCGCATCGACCTTAACCAGCGTGTGATGGATGAGCAGCA
GCAATCGGTCAAAGAGCAGATTGCGGATCTGCTGAATAAAGATTGGCGCGATGCGATCAACAACTGTGAAGCCTTGCTGT
CTGAGACTTCCGCCACACTGCGTGAGCTGCAAGATACCTTGCAAGCGGCAGGCGATGAGTTGCAAACGCAAATCCTCGAT
ATTCAGGAGTGCGTGTATGGCGATCTGGAATTGGATTTCATCGAAGAGACGCTGTTTGCGCTGCAAATGAAGCTCGACCG
CATTACGAGCTGGGGTCAGCAGTCGATTGATCTTTGGATCGGTTACGACCGCCACGTCCACAAGTTTATTCGTACCGCGA
TTGATATGGACCAGAACCGCGCGTTCAGCCAACGTCTGCGTCAGTCAATGAACGACTATTTTGAACAACCTTGGTATCTC
ACTTACGCCGATGCAGAACGCCTATCCGATCTGCGTGATGAAACCTTGACCCTGCGTGACGAAGAAGTTACCGGTCATGT
GCCGACAGAAGTGGAATACGAAGAGCTGCAACAAGTGAACGACGAACTTGCGCAGCGGATTGGCGACATGCTGAAAGTGC
ATAAAGAGCAGGGCGCAGCAATTGATTTAGCCCTTGTGCTGCGTGATTACCTAGCTAGCCATCCACGAACCCATCATTTC
GATTTAGCCCGAATGGTTGTCGACCAAGCGGTAAGGCTGGGTTACTCCGAGTCCGACTACCGCGCTATCCAGCCTGACTG
GACGGCGATCAACGATTTTGGCGCAAAGGTACAAGCGAATGTCATCGACCGATATTAA

Upstream 100 bases:

>100_bases
TGGTGGCACTGGAGCGCAAATTCTGCCGTCAGGAGCCTTACCTCTCATTGGGTCGATACATTCACGTATGGGCTAAGAAA
AAACAATAACAGGAAACACA

Downstream 100 bases:

>100_bases
TGAATACATGCCAGAGAATCTGGCCAAAGCGATTGCGAACCCGCTATTCCCAGCGCTAGATAGTTTGCTGCGTGCGGGAC
GTCATGTTTCCAGTGACGAT

Product: condesin subunit F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSEFTQDTVQKPIDELVTWVKQYDFSLNLPTERLAFLLAIAVLSNERFDEELGEGELHDAFAIVTRLFAESGEASAFRAN
NAINDLVKQRLLSRFTSEMTEGASIYRLTPLAIGITDYYVRHREFSKLKLSIQLSMVADEMAKAVESAQQGGSVAHWRKN
VFGVLKYSVSEIFDRIDLNQRVMDEQQQSVKEQIADLLNKDWRDAINNCEALLSETSATLRELQDTLQAAGDELQTQILD
IQECVYGDLELDFIEETLFALQMKLDRITSWGQQSIDLWIGYDRHVHKFIRTAIDMDQNRAFSQRLRQSMNDYFEQPWYL
TYADAERLSDLRDETLTLRDEEVTGHVPTEVEYEELQQVNDELAQRIGDMLKVHKEQGAAIDLALVLRDYLASHPRTHHF
DLARMVVDQAVRLGYSESDYRAIQPDWTAINDFGAKVQANVIDRY

Sequences:

>Translated_445_residues
MSEFTQDTVQKPIDELVTWVKQYDFSLNLPTERLAFLLAIAVLSNERFDEELGEGELHDAFAIVTRLFAESGEASAFRAN
NAINDLVKQRLLSRFTSEMTEGASIYRLTPLAIGITDYYVRHREFSKLKLSIQLSMVADEMAKAVESAQQGGSVAHWRKN
VFGVLKYSVSEIFDRIDLNQRVMDEQQQSVKEQIADLLNKDWRDAINNCEALLSETSATLRELQDTLQAAGDELQTQILD
IQECVYGDLELDFIEETLFALQMKLDRITSWGQQSIDLWIGYDRHVHKFIRTAIDMDQNRAFSQRLRQSMNDYFEQPWYL
TYADAERLSDLRDETLTLRDEEVTGHVPTEVEYEELQQVNDELAQRIGDMLKVHKEQGAAIDLALVLRDYLASHPRTHHF
DLARMVVDQAVRLGYSESDYRAIQPDWTAINDFGAKVQANVIDRY
>Mature_444_residues
SEFTQDTVQKPIDELVTWVKQYDFSLNLPTERLAFLLAIAVLSNERFDEELGEGELHDAFAIVTRLFAESGEASAFRANN
AINDLVKQRLLSRFTSEMTEGASIYRLTPLAIGITDYYVRHREFSKLKLSIQLSMVADEMAKAVESAQQGGSVAHWRKNV
FGVLKYSVSEIFDRIDLNQRVMDEQQQSVKEQIADLLNKDWRDAINNCEALLSETSATLRELQDTLQAAGDELQTQILDI
QECVYGDLELDFIEETLFALQMKLDRITSWGQQSIDLWIGYDRHVHKFIRTAIDMDQNRAFSQRLRQSMNDYFEQPWYLT
YADAERLSDLRDETLTLRDEEVTGHVPTEVEYEELQQVNDELAQRIGDMLKVHKEQGAAIDLALVLRDYLASHPRTHHFD
LARMVVDQAVRLGYSESDYRAIQPDWTAINDFGAKVQANVIDRY

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid

COG id: COG3006

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukF family

Homologues:

Organism=Escherichia coli, GI1787152, Length=445, Percent_Identity=60.4494382022472, Blast_Score=565, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MUKF_VIBC3 (A5F7I0)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F7I0
- SMR:   A5F7I0
- STRING:   A5F7I0
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1319
- eggNOG:   COG3006
- HOGENOM:   HBG296836
- OMA:   NRFSSEF
- ProtClustDB:   PRK05260
- BioCyc:   VCHO345073:VC0395_A1319-MONOMER
- GO:   GO:0005737
- GO:   GO:0009295
- HAMAP:   MF_01803
- InterPro:   IPR005582
- PIRSF:   PIRSF018282

Pfam domain/function: PF03882 KicB

EC number: NA

Molecular weight: Translated: 51269; Mature: 51138

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFTQDTVQKPIDELVTWVKQYDFSLNLPTERLAFLLAIAVLSNERFDEELGEGELHDA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHH
FAIVTRLFAESGEASAFRANNAINDLVKQRLLSRFTSEMTEGASIYRLTPLAIGITDYYV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHH
RHREFSKLKLSIQLSMVADEMAKAVESAQQGGSVAHWRKNVFGVLKYSVSEIFDRIDLNQ
HHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
RVMDEQQQSVKEQIADLLNKDWRDAINNCEALLSETSATLRELQDTLQAAGDELQTQILD
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQECVYGDLELDFIEETLFALQMKLDRITSWGQQSIDLWIGYDRHVHKFIRTAIDMDQNR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCH
AFSQRLRQSMNDYFEQPWYLTYADAERLSDLRDETLTLRDEEVTGHVPTEVEYEELQQVN
HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHH
DELAQRIGDMLKVHKEQGAAIDLALVLRDYLASHPRTHHFDLARMVVDQAVRLGYSESDY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
RAIQPDWTAINDFGAKVQANVIDRY
CCCCCCCHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure 
SEFTQDTVQKPIDELVTWVKQYDFSLNLPTERLAFLLAIAVLSNERFDEELGEGELHDA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHH
FAIVTRLFAESGEASAFRANNAINDLVKQRLLSRFTSEMTEGASIYRLTPLAIGITDYYV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHH
RHREFSKLKLSIQLSMVADEMAKAVESAQQGGSVAHWRKNVFGVLKYSVSEIFDRIDLNQ
HHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
RVMDEQQQSVKEQIADLLNKDWRDAINNCEALLSETSATLRELQDTLQAAGDELQTQILD
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQECVYGDLELDFIEETLFALQMKLDRITSWGQQSIDLWIGYDRHVHKFIRTAIDMDQNR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCH
AFSQRLRQSMNDYFEQPWYLTYADAERLSDLRDETLTLRDEEVTGHVPTEVEYEELQQVN
HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHH
DELAQRIGDMLKVHKEQGAAIDLALVLRDYLASHPRTHHFDLARMVVDQAVRLGYSESDY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
RAIQPDWTAINDFGAKVQANVIDRY
CCCCCCCHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA