Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 147675265

GI number: 147675265

Start: 2193804

End: 2194184

Strand: Reverse

Name: acpS

Synonym: VC0395_A2035

Alternate gene names: 147675265

Gene position: 2194184-2193804 (Counterclockwise)

Preceding gene: 147675577

Following gene: 147674675

Centisome position: 72.56

GC content: 49.87

Gene sequence:

>381_bases
ATGATCGTTGGACTCGGAACGGATATCGCTGAAATCGAACGGGTTGAGAAAGCGTTGGCGCGCTCAGGAGAAAACTTTGC
GCGCCGCATTCTTACCGATTCTGAACTAGAGCAATTTCATGCTTCGAAGCAACAAGGGCGCTTTTTAGCCAAGCGCTTTG
CCGCCAAAGAGGCAGCTTCGAAAGCTTTGGGAACCGGTATTGCTCAGGGGGTGACTTTCCATGACTTTACCATTAGCCAT
GATAAGTTGGGGAAACCTTTACTGACCTTGAGCGGTCAAGCGGCAGAGTTAGCCTCGCAGCTGCAGATTGAAAATATTCA
TCTTTCCATTTCCGACGAACGCCATTATGCGATGGCGACCGTGATCCTTGAACGCCGTTAA

Upstream 100 bases:

>100_bases
GAACATCGGCCATGCGATCATTGGTCGCGCGGTATTTGATGGTTTAGCGAAAGCCGTCTCCGATATGAAAGCCATCATGG
TTGCTGCGCGTCGATAACGT

Downstream 100 bases:

>100_bases
TGCGGCGTTCATGCTTTGGTTCATTTCAAATCTTTCATTTTCTGACTATATTTTCCTTACGTGCTTAATTTTCCCCAACG
GAAGAATGAGTTTTCTGACT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MIVGLGTDIAEIERVEKALARSGENFARRILTDSELEQFHASKQQGRFLAKRFAAKEAASKALGTGIAQGVTFHDFTISH
DKLGKPLLTLSGQAAELASQLQIENIHLSISDERHYAMATVILERR

Sequences:

>Translated_126_residues
MIVGLGTDIAEIERVEKALARSGENFARRILTDSELEQFHASKQQGRFLAKRFAAKEAASKALGTGIAQGVTFHDFTISH
DKLGKPLLTLSGQAAELASQLQIENIHLSISDERHYAMATVILERR
>Mature_126_residues
MIVGLGTDIAEIERVEKALARSGENFARRILTDSELEQFHASKQQGRFLAKRFAAKEAASKALGTGIAQGVTFHDFTISH
DKLGKPLLTLSGQAAELASQLQIENIHLSISDERHYAMATVILERR

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=55.2845528455285, Blast_Score=144, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_VIBC3 (A5F5H4)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F5H4
- SMR:   A5F5H4
- STRING:   A5F5H4
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2035
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   VHVSITH
- ProtClustDB:   PRK00070
- BioCyc:   VCHO345073:VC0395_A2035-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13859; Mature: 13859

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGLGTDIAEIERVEKALARSGENFARRILTDSELEQFHASKQQGRFLAKRFAAKEAAS
CEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGIAQGVTFHDFTISHDKLGKPLLTLSGQAAELASQLQIENIHLSISDERHYAMAT
HHHHHHHHCCCEEEEEEECHHHCCCCEEEECCCHHHHHHHHHHEEEEEEECCCCHHHHHH
VILERR
EEEECC
>Mature Secondary Structure
MIVGLGTDIAEIERVEKALARSGENFARRILTDSELEQFHASKQQGRFLAKRFAAKEAAS
CEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGIAQGVTFHDFTISHDKLGKPLLTLSGQAAELASQLQIENIHLSISDERHYAMAT
HHHHHHHHCCCEEEEEEECHHHCCCCEEEECCCHHHHHHHHHHEEEEEEECCCCHHHHHH
VILERR
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA