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The map label for this gene is oadA-2 [H]

Identifier: 147674719

GI number: 147674719

Start: 340095

End: 341912

Strand: Reverse

Name: oadA-2 [H]

Synonym: VC0395_A0320

Alternate gene names: 147674719

Gene position: 341912-340095 (Counterclockwise)

Preceding gene: 147673526

Following gene: 147673792

Centisome position: 11.31

GC content: 53.19

Gene sequence:

>1818_bases
GTGAAGGAGAAACCACAGATGACTCAGGCGATCAAACGCGTTGGTGTTACGGATGTCGTATTGCGCGATGCTCACCAATC
TCTTTTTGCCACCCGTTTACGAATTGACGACATGCTGCCGATTGCGCAGCAATTAGATCAGATCGGTTATTGGTCTTTGG
AATGTTGGGGAGGCGCGACCTTTGACAGCTGCATCCGCTTTTTAGGCGAAGACCCATGGCAACGTCTACGTTTACTCAAA
CAAGCCATGCCCAATACGCCACTGCAAATGCTGCTGCGCGGGCAAAACCTGCTCGGCTACCGTCACTATGCCGATGATGT
GGTGGATACTTTTGTAGAGCGTGCGGTGAAAAACGGCATGGATGTATTTCGTGTCTTCGATGCGATGAACGATGTACGCA
ACATGCAACAGGCGCTGCAAGCGGTGAAAAAGATGGGCGCGCATGCGCAAGGCACGCTCTGCTACACCACCAGCCCAGTA
CACAATTTACAAACTTGGGTCGATGTGGCGCAGCAACTGGCGGAGCTCGGCGTCGACTCAATAGCCCTGAAAGATATGGC
CGGCATTTTGACCCCGTATGCCGCTGAAGAGCTAGTGTCTACCCTGAAAAAACAAGTGGATGTCGAGCTGCATCTGCACT
GCCACTCCACCGCGGGCCTTGCCGATATGACTCTGCTTAAAGCGATTGAAGCGGGCGTGGATCGGGTTGATACCGCGATT
TCCAGCATGAGTGGCACTTATGGTCATCCTGCGACCGAATCACTGGTCGCTACCTTGCAAGGCACCGGCTACGACACCGG
ATTGGATATCGCCAAACTCGAACAGATTGCGGCTTACTTCCGTGATGTACGCAAAAAATACCACGCCTTTGAAGGCATGA
TGAAAGGCAGCGATGCGCGCATTTTGGTGGCTCAGGTTCCTGGCGGCATGCTGACCAACATGGAAAGCCAACTCAAACAA
CAAAACGCGCTGGATAAACTCGATTTAGTGCTCGAAGAGATCCCACGCGTGCGTGAAGAACTCGGCTTTTTGCCTCTGGT
CACCCCTACCTCACAAATTGTCGGTACACAAGCGGTGATCAACGTGGTGCTGGGTGAGCGTTACAAAACCATCACCAAGG
AAACCAGCGGTGTGCTGAAAGGGGAATACGGCAAAACGCCAGCACCGGTTAACACTGAGCTGCAAGCTCGCGTGTTGGCG
GGCGCAGAAGCCATTACTTGTCGCCCTGCGGATTTGATTGCCGCCGAAATGCCAACCTTGCAAGACCGCGTATTGCAGCA
AGCTAAAGAGCAGCACATCACCCTCGCCGAGAATGCGATTGATGATGTACTGACCATTGCGCTGTTTGATCAGGTAGGCT
GGAAGTTTTTAGCCAACCGCCATAACCCAGAAGCCTTTGAACCTGCGCCGCAAGCGATAAGTTCAGCCTGCACACCGAAA
GCGCCAACAGAAAAAAGCAAAGTACAGCCAGTGGAAAGTCACGGTGTGTACACCATTACCGTCAACAACCAAAGCTATGT
GGTGAAGGTGGATGAAGGCGGTGACCTGACGCATGTTGCGCCGACGGCATCAACCAACCACGCACCAGTCCCGAGTGCCG
CAGAAGGTGAAAACCTCGCCGCGCCCCTTTCTGGCAACATCTGGAAAATTCATGCCTCAGCCGGTGATGAAGTGGCCGAA
GGCGATGTCTTGCTGATTTTAGAAGCCATGAAGATGGAAACCGAAATCCGCGCGCCACGTGCCGGAGTGATCAGTGCGAT
TGAAGTCAATGAAGGCGATGCCGTACAAGTCGGCGATGCTTTGTTGGTATTGGCGTAA

Upstream 100 bases:

>100_bases
CAACAAGGCCAAAGCCAACCCAAATCAAAACCAAGGTGAATTGCTCGCGGTGCTCACGGCCGCTGTCCATCACCATAAAA
CACAACAAAAACTATCTTAA

Downstream 100 bases:

>100_bases
TCAGAGGCGGAAAGTATGGAAAATATTTTAGCCATGGTGCGTGATTTTGGCCTGTTCCACCTTCAGTGGGGACAGGGCAT
CATGATCCTTGTTGGGTTAG

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MKEKPQMTQAIKRVGVTDVVLRDAHQSLFATRLRIDDMLPIAQQLDQIGYWSLECWGGATFDSCIRFLGEDPWQRLRLLK
QAMPNTPLQMLLRGQNLLGYRHYADDVVDTFVERAVKNGMDVFRVFDAMNDVRNMQQALQAVKKMGAHAQGTLCYTTSPV
HNLQTWVDVAQQLAELGVDSIALKDMAGILTPYAAEELVSTLKKQVDVELHLHCHSTAGLADMTLLKAIEAGVDRVDTAI
SSMSGTYGHPATESLVATLQGTGYDTGLDIAKLEQIAAYFRDVRKKYHAFEGMMKGSDARILVAQVPGGMLTNMESQLKQ
QNALDKLDLVLEEIPRVREELGFLPLVTPTSQIVGTQAVINVVLGERYKTITKETSGVLKGEYGKTPAPVNTELQARVLA
GAEAITCRPADLIAAEMPTLQDRVLQQAKEQHITLAENAIDDVLTIALFDQVGWKFLANRHNPEAFEPAPQAISSACTPK
APTEKSKVQPVESHGVYTITVNNQSYVVKVDEGGDLTHVAPTASTNHAPVPSAAEGENLAAPLSGNIWKIHASAGDEVAE
GDVLLILEAMKMETEIRAPRAGVISAIEVNEGDAVQVGDALLVLA

Sequences:

>Translated_605_residues
MKEKPQMTQAIKRVGVTDVVLRDAHQSLFATRLRIDDMLPIAQQLDQIGYWSLECWGGATFDSCIRFLGEDPWQRLRLLK
QAMPNTPLQMLLRGQNLLGYRHYADDVVDTFVERAVKNGMDVFRVFDAMNDVRNMQQALQAVKKMGAHAQGTLCYTTSPV
HNLQTWVDVAQQLAELGVDSIALKDMAGILTPYAAEELVSTLKKQVDVELHLHCHSTAGLADMTLLKAIEAGVDRVDTAI
SSMSGTYGHPATESLVATLQGTGYDTGLDIAKLEQIAAYFRDVRKKYHAFEGMMKGSDARILVAQVPGGMLTNMESQLKQ
QNALDKLDLVLEEIPRVREELGFLPLVTPTSQIVGTQAVINVVLGERYKTITKETSGVLKGEYGKTPAPVNTELQARVLA
GAEAITCRPADLIAAEMPTLQDRVLQQAKEQHITLAENAIDDVLTIALFDQVGWKFLANRHNPEAFEPAPQAISSACTPK
APTEKSKVQPVESHGVYTITVNNQSYVVKVDEGGDLTHVAPTASTNHAPVPSAAEGENLAAPLSGNIWKIHASAGDEVAE
GDVLLILEAMKMETEIRAPRAGVISAIEVNEGDAVQVGDALLVLA
>Mature_605_residues
MKEKPQMTQAIKRVGVTDVVLRDAHQSLFATRLRIDDMLPIAQQLDQIGYWSLECWGGATFDSCIRFLGEDPWQRLRLLK
QAMPNTPLQMLLRGQNLLGYRHYADDVVDTFVERAVKNGMDVFRVFDAMNDVRNMQQALQAVKKMGAHAQGTLCYTTSPV
HNLQTWVDVAQQLAELGVDSIALKDMAGILTPYAAEELVSTLKKQVDVELHLHCHSTAGLADMTLLKAIEAGVDRVDTAI
SSMSGTYGHPATESLVATLQGTGYDTGLDIAKLEQIAAYFRDVRKKYHAFEGMMKGSDARILVAQVPGGMLTNMESQLKQ
QNALDKLDLVLEEIPRVREELGFLPLVTPTSQIVGTQAVINVVLGERYKTITKETSGVLKGEYGKTPAPVNTELQARVLA
GAEAITCRPADLIAAEMPTLQDRVLQQAKEQHITLAENAIDDVLTIALFDQVGWKFLANRHNPEAFEPAPQAISSACTPK
APTEKSKVQPVESHGVYTITVNNQSYVVKVDEGGDLTHVAPTASTNHAPVPSAAEGENLAAPLSGNIWKIHASAGDEVAE
GDVLLILEAMKMETEIRAPRAGVISAIEVNEGDAVQVGDALLVLA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=633, Percent_Identity=31.2796208530806, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI106049295, Length=633, Percent_Identity=31.2796208530806, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI106049292, Length=633, Percent_Identity=31.2796208530806, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI109150422, Length=150, Percent_Identity=28, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI109150427, Length=150, Percent_Identity=28, Blast_Score=67, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562816, Length=624, Percent_Identity=33.8141025641026, Blast_Score=309, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI17510563, Length=121, Percent_Identity=32.2314049586777, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319695, Length=620, Percent_Identity=30.3225806451613, Blast_Score=295, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6321376, Length=620, Percent_Identity=30.1612903225806, Blast_Score=290, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24652212, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24652210, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24652214, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI19921944, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24652216, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI281363050, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24652224, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24652222, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24652220, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24652218, Length=632, Percent_Identity=32.9113924050633, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24582381, Length=193, Percent_Identity=27.4611398963731, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 65840; Mature: 65840

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKPQMTQAIKRVGVTDVVLRDAHQSLFATRLRIDDMLPIAQQLDQIGYWSLECWGGAT
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
FDSCIRFLGEDPWQRLRLLKQAMPNTPLQMLLRGQNLLGYRHYADDVVDTFVERAVKNGM
HHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCH
DVFRVFDAMNDVRNMQQALQAVKKMGAHAQGTLCYTTSPVHNLQTWVDVAQQLAELGVDS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHH
IALKDMAGILTPYAAEELVSTLKKQVDVELHLHCHSTAGLADMTLLKAIEAGVDRVDTAI
HHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SSMSGTYGHPATESLVATLQGTGYDTGLDIAKLEQIAAYFRDVRKKYHAFEGMMKGSDAR
HHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ILVAQVPGGMLTNMESQLKQQNALDKLDLVLEEIPRVREELGFLPLVTPTSQIVGTQAVI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
NVVLGERYKTITKETSGVLKGEYGKTPAPVNTELQARVLAGAEAITCRPADLIAAEMPTL
HHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHCCCEEECCCHHHHHHCCCHH
QDRVLQQAKEQHITLAENAIDDVLTIALFDQVGWKFLANRHNPEAFEPAPQAISSACTPK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCC
APTEKSKVQPVESHGVYTITVNNQSYVVKVDEGGDLTHVAPTASTNHAPVPSAAEGENLA
CCCCCCCCCCHHHCCEEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCC
APLSGNIWKIHASAGDEVAEGDVLLILEAMKMETEIRAPRAGVISAIEVNEGDAVQVGDA
CCCCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCE
LLVLA
EEEEC
>Mature Secondary Structure
MKEKPQMTQAIKRVGVTDVVLRDAHQSLFATRLRIDDMLPIAQQLDQIGYWSLECWGGAT
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
FDSCIRFLGEDPWQRLRLLKQAMPNTPLQMLLRGQNLLGYRHYADDVVDTFVERAVKNGM
HHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCH
DVFRVFDAMNDVRNMQQALQAVKKMGAHAQGTLCYTTSPVHNLQTWVDVAQQLAELGVDS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHH
IALKDMAGILTPYAAEELVSTLKKQVDVELHLHCHSTAGLADMTLLKAIEAGVDRVDTAI
HHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SSMSGTYGHPATESLVATLQGTGYDTGLDIAKLEQIAAYFRDVRKKYHAFEGMMKGSDAR
HHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ILVAQVPGGMLTNMESQLKQQNALDKLDLVLEEIPRVREELGFLPLVTPTSQIVGTQAVI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
NVVLGERYKTITKETSGVLKGEYGKTPAPVNTELQARVLAGAEAITCRPADLIAAEMPTL
HHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHCCCEEECCCHHHHHHCCCHH
QDRVLQQAKEQHITLAENAIDDVLTIALFDQVGWKFLANRHNPEAFEPAPQAISSACTPK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCC
APTEKSKVQPVESHGVYTITVNNQSYVVKVDEGGDLTHVAPTASTNHAPVPSAAEGENLA
CCCCCCCCCCHHHCCEEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCC
APLSGNIWKIHASAGDEVAEGDVLLILEAMKMETEIRAPRAGVISAIEVNEGDAVQVGDA
CCCCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCE
LLVLA
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]