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The map label for this gene is endo I [H]

Identifier: 147674641

GI number: 147674641

Start: 631354

End: 633636

Strand: Direct

Name: endo I [H]

Synonym: VC0395_A0592

Alternate gene names: 147674641

Gene position: 631354-633636 (Clockwise)

Preceding gene: 147675425

Following gene: 147673672

Centisome position: 20.88

GC content: 51.47

Gene sequence:

>2283_bases
TTGGGTCAATACACCATCGAAGCGATCGCTTACGATGCAGCAGGTCATCAAACGCAAACCCCAATGGTGACAGTGAACGC
CAAAGAAATGGGCACGGGCAACCTAAGTTGTGACATCAAACAGATCTATCGTGAAGATGGCACTGAGTGTATGGGTGACG
ATCACCCGCGCCGTATCATCGGTTATTACACCTCATGGCGTACTGGTAAAAACGGTCTGCCAGCGTACCTCGCCGGCGAT
CTGCCTTGGGAAAAACTGACCCACATTAACTACGCGTTCGCCAGCATCAACAAGTCTGACTTCAGCATGCAAGTGGATGA
TTCCGCGACCAAGATGACGTGGGAAAATGTACCGGGTGCCGAGATGGATCCTTCACTGCCATACCAAGGTCACTTCAACC
TGCTGAGCAAGTTTAAGAAACAGTACCCCGATGTGAAAACGCTGATTTCTGTCGGTGGTTGGGCGGAAACCGGTGGTTTC
TATCCAATGACGACCGATCTGGCTTCTTGTTCAGTGAACATGGAAGGCATCAAGGCGTTCAACAAATCGGCGGTCGATTT
CATCCGTCAATACGATTTTGATGGCGTGGATATCGACTACGAATACCCATCATCAATGAAAGATTCCGGTAATCCGGTCG
ATTTCGAGCAGTCGAACAAGTGTCGTGGCCAGTTGTGGGATAACTACATGGTGATGATGACCGAACTGCGCAAAGCGCTG
GATAAAGCGGGCGAAGAAGATGGCCGTCGTTATATGCTGACTATCGCGTCACCTTCATCAGCTTACCTGCTGCGTGGTAT
GCAAGACTTCGCGATGCAAGATGTACTGGATTACGTCAACATCATGTCTTACGACCTGCATGGTACGTGGAACGAGTTTG
TCGGCCCACAAGCCGCACTGTTTGATGATGGTAAAGATGCTGAGCTGGCCAAATGGGGCGTGTACACGACTGCAGAATAT
CAAGGCATTGGCTACTTAAACCAAGCGTGGACGCACCACTTCTTCCGTGGCGCCTTTAAACCAAGCCAAATCAACATGGG
GATTCCTTACTACACCCGTGGCTGGCAAGGCGTGAGCGGCGGCGATAAAGGTCTATGGGGTCGTGCGGTTGAGCCAAACC
AATCGTCATGTCCAGAAGGCACCACTGTTTGTGGTTGGGGCGCGGAAGGTACCGATAACATCTGGCATGATGTGGATGCC
AACGGTAACGAAATCAAAGCCGGTGTGGTACCCATGTGGCACGCGATGAACCTGATGCACGCTGAAAAATTGGGTATTGA
CGGTATGCCAAGTTACGGCCCAGCGTGGGGTATGGATCCAAACAACCCGAAACACCTGATTGAAGGCAAATACGAGCGTG
TGTGGAGTCAAGAGCTGCAAACGGCATGGCTTTGGAACGACACCAAAAAAGTATTCCTGAGCATTGAAGATAAAGACTCA
CTGAAGCCAAAACTGGATTACATCGTCGATAACGGTTTAGGCGGCATGATGATTTGGGAGATGGCGGGTGACTACTCGTA
TGATGCGGTGAAACGCGAATACGTGATCGGTTCTGACATGACTTCTTATGCCCATGAAGTGTTTGCCGCGGCGAAGCCGA
TGGATATTCGTCATAACGATCTGCCACAACCAGACTCGGTGATTGACGTTACGGTATCGACCACAGAATGGCCAGAAGGC
GATAGCAACTACCCAATCAACCCGAAATTGGTGTTTACCAACCACTCAAATGTGGCGATTCCGGGTGGTTCTACGATTGA
GTTCCTGATGCCAACGTCAACCGGTGATATCGTCAAAGATTGGAGCGGTGCTGGTCTGAAAGTGATTGAAAGCGGTCATA
CCGGCAGCAACTTCTCGGTGAATGGTGAGAAGAAACTGTTCCACAAAGTGGCCGTGACACTGCGCTCAACCGAAACGATC
CCTGCGGGCGGTGAGTACAGCGTCGATATGGTGTACTACACCCCAGTCTCTGGCGTGGCTAACGGCGTGCGCTTTATCGT
GGGTAACGAAACGGTCGGCTTGAAGAAAGACTTCCCAACATTGCCAGCGTTTGAAGGTGCCACCGATGGCGGCAATGGGA
ACGAAGGCGGTGCGGGTCAATCTTGTGCCGATGCCGGCATCAACCCTAATGGCTTGAAAGTGTACCCAGAGTTTCCACGT
GGCGACCACGCGGCAGGCGGTGACCAACTGATCCACAATGGTTCTGTATGGCAAGCCAACTGGTGGACGAACAGTACACC
ATCCAGCGCCGATGCATCATGGAAAGCGGTGTGCAAAATCTAA

Upstream 100 bases:

>100_bases
CGAAAATAATGATCTCACCGCAGTTGAGTTTTTGGTGAATGGCGAATCGATTGGCCGTGTTACTCAGGCTCCATATCAAC
TGGCTTAGACTCCGGTAGCT

Downstream 100 bases:

>100_bases
GTTAACTACCGTTCATGAAACATAAGCCCAGCCATTTGGCTGGGCTTTTCTATGCTTGGAAAAAGGGATAAGAAAAATGG
AAAAGGCGTTTAACGCGCCA

Product: putative chitinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MGQYTIEAIAYDAAGHQTQTPMVTVNAKEMGTGNLSCDIKQIYREDGTECMGDDHPRRIIGYYTSWRTGKNGLPAYLAGD
LPWEKLTHINYAFASINKSDFSMQVDDSATKMTWENVPGAEMDPSLPYQGHFNLLSKFKKQYPDVKTLISVGGWAETGGF
YPMTTDLASCSVNMEGIKAFNKSAVDFIRQYDFDGVDIDYEYPSSMKDSGNPVDFEQSNKCRGQLWDNYMVMMTELRKAL
DKAGEEDGRRYMLTIASPSSAYLLRGMQDFAMQDVLDYVNIMSYDLHGTWNEFVGPQAALFDDGKDAELAKWGVYTTAEY
QGIGYLNQAWTHHFFRGAFKPSQINMGIPYYTRGWQGVSGGDKGLWGRAVEPNQSSCPEGTTVCGWGAEGTDNIWHDVDA
NGNEIKAGVVPMWHAMNLMHAEKLGIDGMPSYGPAWGMDPNNPKHLIEGKYERVWSQELQTAWLWNDTKKVFLSIEDKDS
LKPKLDYIVDNGLGGMMIWEMAGDYSYDAVKREYVIGSDMTSYAHEVFAAAKPMDIRHNDLPQPDSVIDVTVSTTEWPEG
DSNYPINPKLVFTNHSNVAIPGGSTIEFLMPTSTGDIVKDWSGAGLKVIESGHTGSNFSVNGEKKLFHKVAVTLRSTETI
PAGGEYSVDMVYYTPVSGVANGVRFIVGNETVGLKKDFPTLPAFEGATDGGNGNEGGAGQSCADAGINPNGLKVYPEFPR
GDHAAGGDQLIHNGSVWQANWWTNSTPSSADASWKAVCKI

Sequences:

>Translated_760_residues
MGQYTIEAIAYDAAGHQTQTPMVTVNAKEMGTGNLSCDIKQIYREDGTECMGDDHPRRIIGYYTSWRTGKNGLPAYLAGD
LPWEKLTHINYAFASINKSDFSMQVDDSATKMTWENVPGAEMDPSLPYQGHFNLLSKFKKQYPDVKTLISVGGWAETGGF
YPMTTDLASCSVNMEGIKAFNKSAVDFIRQYDFDGVDIDYEYPSSMKDSGNPVDFEQSNKCRGQLWDNYMVMMTELRKAL
DKAGEEDGRRYMLTIASPSSAYLLRGMQDFAMQDVLDYVNIMSYDLHGTWNEFVGPQAALFDDGKDAELAKWGVYTTAEY
QGIGYLNQAWTHHFFRGAFKPSQINMGIPYYTRGWQGVSGGDKGLWGRAVEPNQSSCPEGTTVCGWGAEGTDNIWHDVDA
NGNEIKAGVVPMWHAMNLMHAEKLGIDGMPSYGPAWGMDPNNPKHLIEGKYERVWSQELQTAWLWNDTKKVFLSIEDKDS
LKPKLDYIVDNGLGGMMIWEMAGDYSYDAVKREYVIGSDMTSYAHEVFAAAKPMDIRHNDLPQPDSVIDVTVSTTEWPEG
DSNYPINPKLVFTNHSNVAIPGGSTIEFLMPTSTGDIVKDWSGAGLKVIESGHTGSNFSVNGEKKLFHKVAVTLRSTETI
PAGGEYSVDMVYYTPVSGVANGVRFIVGNETVGLKKDFPTLPAFEGATDGGNGNEGGAGQSCADAGINPNGLKVYPEFPR
GDHAAGGDQLIHNGSVWQANWWTNSTPSSADASWKAVCKI
>Mature_759_residues
GQYTIEAIAYDAAGHQTQTPMVTVNAKEMGTGNLSCDIKQIYREDGTECMGDDHPRRIIGYYTSWRTGKNGLPAYLAGDL
PWEKLTHINYAFASINKSDFSMQVDDSATKMTWENVPGAEMDPSLPYQGHFNLLSKFKKQYPDVKTLISVGGWAETGGFY
PMTTDLASCSVNMEGIKAFNKSAVDFIRQYDFDGVDIDYEYPSSMKDSGNPVDFEQSNKCRGQLWDNYMVMMTELRKALD
KAGEEDGRRYMLTIASPSSAYLLRGMQDFAMQDVLDYVNIMSYDLHGTWNEFVGPQAALFDDGKDAELAKWGVYTTAEYQ
GIGYLNQAWTHHFFRGAFKPSQINMGIPYYTRGWQGVSGGDKGLWGRAVEPNQSSCPEGTTVCGWGAEGTDNIWHDVDAN
GNEIKAGVVPMWHAMNLMHAEKLGIDGMPSYGPAWGMDPNNPKHLIEGKYERVWSQELQTAWLWNDTKKVFLSIEDKDSL
KPKLDYIVDNGLGGMMIWEMAGDYSYDAVKREYVIGSDMTSYAHEVFAAAKPMDIRHNDLPQPDSVIDVTVSTTEWPEGD
SNYPINPKLVFTNHSNVAIPGGSTIEFLMPTSTGDIVKDWSGAGLKVIESGHTGSNFSVNGEKKLFHKVAVTLRSTETIP
AGGEYSVDMVYYTPVSGVANGVRFIVGNETVGLKKDFPTLPAFEGATDGGNGNEGGAGQSCADAGINPNGLKVYPEFPRG
DHAAGGDQLIHNGSVWQANWWTNSTPSSADASWKAVCKI

Specific function: Hydrolyzes chitin oligosaccharides; (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5,6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin, glucosamine oligosaccharides, glycoproteins and glycopeptides containing (GlcNAc)2 [H]

COG id: COG3325

COG function: function code G; Chitinase

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 18 family [H]

Homologues:

Organism=Homo sapiens, GI58386720, Length=323, Percent_Identity=26.0061919504644, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4502809, Length=310, Percent_Identity=28.0645161290323, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI133893286, Length=323, Percent_Identity=26.625386996904, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI144226251, Length=448, Percent_Identity=20.7589285714286, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI68533255, Length=301, Percent_Identity=22.5913621262458, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI68533253, Length=301, Percent_Identity=22.5913621262458, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI42542398, Length=206, Percent_Identity=27.6699029126214, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995504, Length=462, Percent_Identity=27.0562770562771, Blast_Score=132, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17559362, Length=460, Percent_Identity=25.2173913043478, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17563680, Length=455, Percent_Identity=24.6153846153846, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17551250, Length=298, Percent_Identity=26.8456375838926, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536195, Length=464, Percent_Identity=21.551724137931, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531695, Length=469, Percent_Identity=23.2409381663113, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17535579, Length=455, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535575, Length=455, Percent_Identity=23.5164835164835, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320579, Length=468, Percent_Identity=22.008547008547, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358195, Length=257, Percent_Identity=29.9610894941634, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI221330815, Length=267, Percent_Identity=28.4644194756554, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24655584, Length=311, Percent_Identity=24.7588424437299, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI161077700, Length=458, Percent_Identity=23.5807860262009, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI221329807, Length=455, Percent_Identity=23.0769230769231, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45550474, Length=449, Percent_Identity=22.71714922049, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI116007452, Length=323, Percent_Identity=21.9814241486068, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI22024049, Length=253, Percent_Identity=25.296442687747, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17137374, Length=469, Percent_Identity=22.8144989339019, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584613, Length=469, Percent_Identity=22.8144989339019, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584615, Length=469, Percent_Identity=22.8144989339019, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003610
- InterPro:   IPR009470
- InterPro:   IPR011583
- InterPro:   IPR001223
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF02839 CBM_5_12; PF06483 ChiC; PF00704 Glyco_hydro_18 [H]

EC number: =3.2.1.14 [H]

Molecular weight: Translated: 83786; Mature: 83655

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS01095 CHITINASE_18

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQYTIEAIAYDAAGHQTQTPMVTVNAKEMGTGNLSCDIKQIYREDGTECMGDDHPRRII
CCCEEEEEEEEECCCCCCCCCEEEEEHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEE
GYYTSWRTGKNGLPAYLAGDLPWEKLTHINYAFASINKSDFSMQVDDSATKMTWENVPGA
EEEECCCCCCCCCCEEEECCCCHHHHHHCEEEEEECCCCCCEEEECCCCCEEEECCCCCC
EMDPSLPYQGHFNLLSKFKKQYPDVKTLISVGGWAETGGFYPMTTDLASCSVNMEGIKAF
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCHHCCCCCEEECCHHHCCCCHHHHHHH
NKSAVDFIRQYDFDGVDIDYEYPSSMKDSGNPVDFEQSNKCRGQLWDNYMVMMTELRKAL
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHH
DKAGEEDGRRYMLTIASPSSAYLLRGMQDFAMQDVLDYVNIMSYDLHGTWNEFVGPQAAL
HHCCCCCCCEEEEEEECCCHHHHHHCHHHHHHHHHHHHHHHHEEECCCCHHHHCCCCEEE
FDDGKDAELAKWGVYTTAEYQGIGYLNQAWTHHFFRGAFKPSQINMGIPYYTRGWQGVSG
ECCCCCCCHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCEECCCCCCCC
GDKGLWGRAVEPNQSSCPEGTTVCGWGAEGTDNIWHDVDANGNEIKAGVVPMWHAMNLMH
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHH
AEKLGIDGMPSYGPAWGMDPNNPKHLIEGKYERVWSQELQTAWLWNDTKKVFLSIEDKDS
HHHCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHEEEEECCCEEEEEEECCCCC
LKPKLDYIVDNGLGGMMIWEMAGDYSYDAVKREYVIGSDMTSYAHEVFAAAKPMDIRHND
CCCCEEEEEECCCCCEEEEEECCCCCHHHHHHEEEECCCHHHHHHHHHHHCCCCCCCCCC
LPQPDSVIDVTVSTTEWPEGDSNYPINPKLVFTNHSNVAIPGGSTIEFLMPTSTGDIVKD
CCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEEECCCCCCHHHC
WSGAGLKVIESGHTGSNFSVNGEKKLFHKVAVTLRSTETIPAGGEYSVDMVYYTPVSGVA
CCCCCEEEEECCCCCCCEEECCHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCHHHHC
NGVRFIVGNETVGLKKDFPTLPAFEGATDGGNGNEGGAGQSCADAGINPNGLKVYPEFPR
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCC
GDHAAGGDQLIHNGSVWQANWWTNSTPSSADASWKAVCKI
CCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
GQYTIEAIAYDAAGHQTQTPMVTVNAKEMGTGNLSCDIKQIYREDGTECMGDDHPRRII
CCEEEEEEEEECCCCCCCCCEEEEEHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEE
GYYTSWRTGKNGLPAYLAGDLPWEKLTHINYAFASINKSDFSMQVDDSATKMTWENVPGA
EEEECCCCCCCCCCEEEECCCCHHHHHHCEEEEEECCCCCCEEEECCCCCEEEECCCCCC
EMDPSLPYQGHFNLLSKFKKQYPDVKTLISVGGWAETGGFYPMTTDLASCSVNMEGIKAF
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCHHCCCCCEEECCHHHCCCCHHHHHHH
NKSAVDFIRQYDFDGVDIDYEYPSSMKDSGNPVDFEQSNKCRGQLWDNYMVMMTELRKAL
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHH
DKAGEEDGRRYMLTIASPSSAYLLRGMQDFAMQDVLDYVNIMSYDLHGTWNEFVGPQAAL
HHCCCCCCCEEEEEEECCCHHHHHHCHHHHHHHHHHHHHHHHEEECCCCHHHHCCCCEEE
FDDGKDAELAKWGVYTTAEYQGIGYLNQAWTHHFFRGAFKPSQINMGIPYYTRGWQGVSG
ECCCCCCCHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCEECCCCCCCC
GDKGLWGRAVEPNQSSCPEGTTVCGWGAEGTDNIWHDVDANGNEIKAGVVPMWHAMNLMH
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHH
AEKLGIDGMPSYGPAWGMDPNNPKHLIEGKYERVWSQELQTAWLWNDTKKVFLSIEDKDS
HHHCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHEEEEECCCEEEEEEECCCCC
LKPKLDYIVDNGLGGMMIWEMAGDYSYDAVKREYVIGSDMTSYAHEVFAAAKPMDIRHND
CCCCEEEEEECCCCCEEEEEECCCCCHHHHHHEEEECCCHHHHHHHHHHHCCCCCCCCCC
LPQPDSVIDVTVSTTEWPEGDSNYPINPKLVFTNHSNVAIPGGSTIEFLMPTSTGDIVKD
CCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEEECCCCCCHHHC
WSGAGLKVIESGHTGSNFSVNGEKKLFHKVAVTLRSTETIPAGGEYSVDMVYYTPVSGVA
CCCCCEEEEECCCCCCCEEECCHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCHHHHC
NGVRFIVGNETVGLKKDFPTLPAFEGATDGGNGNEGGAGQSCADAGINPNGLKVYPEFPR
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCC
GDHAAGGDQLIHNGSVWQANWWTNSTPSSADASWKAVCKI
CCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969204 [H]