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The map label for this gene is rtxD [H]

Identifier: 147674597

GI number: 147674597

Start: 1103802

End: 1105205

Strand: Reverse

Name: rtxD [H]

Synonym: VC0395_A1057

Alternate gene names: 147674597

Gene position: 1105205-1103802 (Counterclockwise)

Preceding gene: 147675369

Following gene: 147675517

Centisome position: 36.55

GC content: 50.36

Gene sequence:

>1404_bases
ATGGCAGCTTCAGCAAGAGCTCAAACAAGAGGAAGCCTCCGCATGAACACCATCATGAAGCGTTTCTTTGGTCAAAAGTC
ACCACATCAACCCACAGAACATCACTATGAGTTTTTGCCCGCACATCTTGCTTTGGCTCAGCGTCCTCCCTCGCCTTTTG
CTCGCGTGACTGCGCTTACGCTCAGCTTAGGTGTGCTCGCAGCCTTGCTCTGGGCGTATTGGGGAAAATTAGATGTACAG
GCCACCGCCACTGGCCGCCTTGTTGTATCTGGGCGTTCGCAAGTGATTCAGTCTTATGAGCAAAGCCGACTGTTAAGCAT
CCACGTCAGAGATGGTCAACGAGTTGAAAAAGGCGCCCCATTGCTGACTCTTGATACCTTGGGCGTCAATCAAGATATTA
CGCGTTTGGTCAGCCAAGCAGAGTTTCAAACGAACGAGTTGATCCGCTATCGCACCTTGCTTAATGACCAGCTCTTGACT
CATGACCCAATGTTTACCGCTCTACCAGCCGAACAACAAGCTTTGATCCATGAAAACTATCTCAGCGAAAAAAACGAATT
CGACTCAACGCTGGCAAGCATCACCGCCGAGATGAAGGTGAACCGCACGTCGCAGGCCGCGCGCCAAAGCGATATCCATG
CGTTGTTGCAGCTCACAGAAAACATCAGTCAGCGCCTTGCTGCCCGCAAAAAGCTCAACCAAGTCAAAGTGATCGGTCAT
GTCGAGTATCTTGAACAAGAAAAAGAGCTGCTCGAAGCGCAGCGCCAAGTGGCCCAACAGCGAGCCGAGCTGGAAGTGCT
TAAATCGCAATATGAAAGCCTTGAAGAGCGGCTAACGGGCTTCAAAGCGCAAAAGCAGCGAGAGTGGTTGGAAAAGCGCA
GACAGGCCAGATTGCAATTGGCTTCTTTAAATCAAGAACTTTCTAAGGTTCGTGAGCGTGAGCAACTCGAAATCATCCGC
TCGCCCGTTGACGGCACTGTGCAACAGTTGAGTGTCTATACCCTTGGGGCAGTACTGCAACCGGCACAAAACTTGATGAT
CATTGTGCCTGAGAACCGTGTGCAACAGGCAGAAGTGCAAATTCTCAATAAAGATGTCGGTTTCGTGTACCCAGGCCAAT
CGGTCACGGTCAAAGTCGATGCCTTCCCCTACACACGATACGGCACAATCGATGCCGAGCTACTCAGTATCTCGCGAGAC
TCAACAACAGATGAACAGTTAGGGCTGGTGTTCCCTGCTCAAATTCAGCTAAAAACCAACCATATTATGATTGATGGACA
AACGGTCGAACTCACTCCCGGCATGTCGGTCGTCGCGGAAATCAAAACCGATAAACGACGTGTGATTGACTATCTGCTTA
GCCCGATTCAGGAATACCAAGCTGAAGCGTTGAGGGAGAGATAG

Upstream 100 bases:

>100_bases
TGCGTGATTGCGATCGCATCATAGTGCTTCATCAGGGCACGATTGTTGAGCAAGGCTCACACCAACAATTACTCGCCTAC
GGCAAACAATACAAACAGTT

Downstream 100 bases:

>100_bases
CAATGAACACCCGTTTTACAACCGACGCTCATAGGCTTGCTGAACAAACGTTACCACAAGAGTCTCCAAGAACTAATTGG
GGTATCGAAGCTGTGGTCTA

Product: RTX toxin transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MAASARAQTRGSLRMNTIMKRFFGQKSPHQPTEHHYEFLPAHLALAQRPPSPFARVTALTLSLGVLAALLWAYWGKLDVQ
ATATGRLVVSGRSQVIQSYEQSRLLSIHVRDGQRVEKGAPLLTLDTLGVNQDITRLVSQAEFQTNELIRYRTLLNDQLLT
HDPMFTALPAEQQALIHENYLSEKNEFDSTLASITAEMKVNRTSQAARQSDIHALLQLTENISQRLAARKKLNQVKVIGH
VEYLEQEKELLEAQRQVAQQRAELEVLKSQYESLEERLTGFKAQKQREWLEKRRQARLQLASLNQELSKVREREQLEIIR
SPVDGTVQQLSVYTLGAVLQPAQNLMIIVPENRVQQAEVQILNKDVGFVYPGQSVTVKVDAFPYTRYGTIDAELLSISRD
STTDEQLGLVFPAQIQLKTNHIMIDGQTVELTPGMSVVAEIKTDKRRVIDYLLSPIQEYQAEALRER

Sequences:

>Translated_467_residues
MAASARAQTRGSLRMNTIMKRFFGQKSPHQPTEHHYEFLPAHLALAQRPPSPFARVTALTLSLGVLAALLWAYWGKLDVQ
ATATGRLVVSGRSQVIQSYEQSRLLSIHVRDGQRVEKGAPLLTLDTLGVNQDITRLVSQAEFQTNELIRYRTLLNDQLLT
HDPMFTALPAEQQALIHENYLSEKNEFDSTLASITAEMKVNRTSQAARQSDIHALLQLTENISQRLAARKKLNQVKVIGH
VEYLEQEKELLEAQRQVAQQRAELEVLKSQYESLEERLTGFKAQKQREWLEKRRQARLQLASLNQELSKVREREQLEIIR
SPVDGTVQQLSVYTLGAVLQPAQNLMIIVPENRVQQAEVQILNKDVGFVYPGQSVTVKVDAFPYTRYGTIDAELLSISRD
STTDEQLGLVFPAQIQLKTNHIMIDGQTVELTPGMSVVAEIKTDKRRVIDYLLSPIQEYQAEALRER
>Mature_466_residues
AASARAQTRGSLRMNTIMKRFFGQKSPHQPTEHHYEFLPAHLALAQRPPSPFARVTALTLSLGVLAALLWAYWGKLDVQA
TATGRLVVSGRSQVIQSYEQSRLLSIHVRDGQRVEKGAPLLTLDTLGVNQDITRLVSQAEFQTNELIRYRTLLNDQLLTH
DPMFTALPAEQQALIHENYLSEKNEFDSTLASITAEMKVNRTSQAARQSDIHALLQLTENISQRLAARKKLNQVKVIGHV
EYLEQEKELLEAQRQVAQQRAELEVLKSQYESLEERLTGFKAQKQREWLEKRRQARLQLASLNQELSKVREREQLEIIRS
PVDGTVQQLSVYTLGAVLQPAQNLMIIVPENRVQQAEVQILNKDVGFVYPGQSVTVKVDAFPYTRYGTIDAELLSISRDS
TTDEQLGLVFPAQIQLKTNHIMIDGQTVELTPGMSVVAEIKTDKRRVIDYLLSPIQEYQAEALRER

Specific function: Involved in the transport of the Leukotoxin [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 52964; Mature: 52833

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASARAQTRGSLRMNTIMKRFFGQKSPHQPTEHHYEFLPAHLALAQRPPSPFARVTALT
CCCCCCCHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LSLGVLAALLWAYWGKLDVQATATGRLVVSGRSQVIQSYEQSRLLSIHVRDGQRVEKGAP
HHHHHHHHHHHHHHCCEEEEEECCCEEEECCHHHHHHHHHHCCEEEEEECCCCCHHCCCC
LLTLDTLGVNQDITRLVSQAEFQTNELIRYRTLLNDQLLTHDPMFTALPAEQQALIHENY
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEECCCHHHHHHHHHH
LSEKNEFDSTLASITAEMKVNRTSQAARQSDIHALLQLTENISQRLAARKKLNQVKVIGH
HCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEYLEQEKELLEAQRQVAQQRAELEVLKSQYESLEERLTGFKAQKQREWLEKRRQARLQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ASLNQELSKVREREQLEIIRSPVDGTVQQLSVYTLGAVLQPAQNLMIIVPENRVQQAEVQ
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
ILNKDVGFVYPGQSVTVKVDAFPYTRYGTIDAELLSISRDSTTDEQLGLVFPAQIQLKTN
HHCCCCCEEECCCEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCEEECCEEEEEEC
HIMIDGQTVELTPGMSVVAEIKTDKRRVIDYLLSPIQEYQAEALRER
EEEEECEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AASARAQTRGSLRMNTIMKRFFGQKSPHQPTEHHYEFLPAHLALAQRPPSPFARVTALT
CCCCCCHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LSLGVLAALLWAYWGKLDVQATATGRLVVSGRSQVIQSYEQSRLLSIHVRDGQRVEKGAP
HHHHHHHHHHHHHHCCEEEEEECCCEEEECCHHHHHHHHHHCCEEEEEECCCCCHHCCCC
LLTLDTLGVNQDITRLVSQAEFQTNELIRYRTLLNDQLLTHDPMFTALPAEQQALIHENY
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEECCCHHHHHHHHHH
LSEKNEFDSTLASITAEMKVNRTSQAARQSDIHALLQLTENISQRLAARKKLNQVKVIGH
HCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEYLEQEKELLEAQRQVAQQRAELEVLKSQYESLEERLTGFKAQKQREWLEKRRQARLQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ASLNQELSKVREREQLEIIRSPVDGTVQQLSVYTLGAVLQPAQNLMIIVPENRVQQAEVQ
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
ILNKDVGFVYPGQSVTVKVDAFPYTRYGTIDAELLSISRDSTTDEQLGLVFPAQIQLKTN
HHCCCCCEEECCCEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCEEECCEEEEEEC
HIMIDGQTVELTPGMSVVAEIKTDKRRVIDYLLSPIQEYQAEALRER
EEEEECEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040588; 2914876; 2707120 [H]