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The map label for this gene is acoR [H]

Identifier: 147674581

GI number: 147674581

Start: 1510304

End: 1512067

Strand: Reverse

Name: acoR [H]

Synonym: VC0395_A1413

Alternate gene names: 147674581

Gene position: 1512067-1510304 (Counterclockwise)

Preceding gene: 147673546

Following gene: 147675532

Centisome position: 50.0

GC content: 50.4

Gene sequence:

>1764_bases
GTGATGCAACTTCAACAGCTTAGCCATGTTAATTGGCTGGTGAACTCTTGGCAGCGTAGTGAACAGGCGGGGTTGACCCA
GCAGAGTCGTGCGCAAGATATTCGCTTGAGTGACAACAAACTTAAGGAGCGTCGCCAAGAGCTCGCGGGGCTGATTGACA
CGGTCAGCCGATTTGCACTACCGCTGTTCTACCAACTGTTTGCACACAGTGACAGCCGTTTAATTTTGACCGACCAACAC
GGCGTGATCATCGGCAGTTGGGGGCAAGCGAGATTTCGTGAAAAACTGAGCCAAATCGCGCTAAGCTCCGGCGCATGTTG
GCAAGAGCCGATCAAAGGTACCAACGCTATTGGCACGGCTTTGATTGAGCAAAAACCCATTTCGGTGATTGGTGAGCAGC
ACTTTATTCAGCATCATCACTTTATCAGTTGTTCCGCGAGCCCGATTTTTGATTACACCGGACAGCTGATCGGAGTGTTA
GACATCACCAGCGAGCAGCAGAAACACACGCTTTCAACCCAAGTTGTGGTGCAGAATATGGTACAACTGGTTGAAAATCA
GCTCCTTAACCAGATACCACATGGCCATGTACGAATCGATCTCGCCTGTGAACCCTCGTTACTGAGCAGTGGCTGGCAAG
GCGTAATTATTGCGGATGAATCGGGCCAGATATTGGCGCATAACCAAGTCGCAGGTCAGTTATTAGCGCAAGGCAGAGTG
ATTGGTCAATCGGTGGAGCAGGTGCTGCCACGGCCACAGACGCATGCATCATTTATCTATACCACCACACCGCTCCACTC
CAAACAACATCGTACCCGCGCGTTAACCCCCGCCAGTGATCTGCATTTTGGGGATGCGGAGGTGGAGCGCTGTTGGCAAC
AGGCTAATCGGGTAATTGATAAAGATATCCGCTTGCTGATCCTTGGCCAAACTGGGGTGGGTAAAAATGAATTTGTTAAA
GCGCTGCACAAAAATAGCCAGCGTAAAAATGGTCCTTTAGTCGCGGTAAATTGTGGTGCGCTGGCCAAGGAGCTGGTGGA
GGCGGAGCTGTTTGGCTATGTCGCTGGCGCCTTTACCGGAGCCAGTCATAAAGGTTACCAAGGGAAAGTGCGTTTAGCCG
ACAAAGGCATTTTGTTTCTGGATGAAATCGCTGATTTACCTCTAGATGCGCAAAGTCGCTTACTGCATGTGTTGCAAGAC
AAAACCGTGCTGCCGGTGGGTTCTAATCACGCCACCAAAGTCGACATTCAGATTATTGCTGCGACTCACAAAAACCTTGA
ACAGTTGGTCACACAAGGGCTGTTTCGCCAAGATCTCTACTACCGACTCAGTGATTTGGTTGTCGAGCTGCCCAGCTTCC
AGCAGCGTCAAGATAGACAAGCCCTAATCCACCATATTCATCGCCGCTACAGTGATGCTGGCCAACAAATCTGTGGTGAC
TTGATGCAAAGGCTACTCGCTTATCACTGGCCGGGTAATTTACGCGAGCTAGATAGCCTAATCAAAGTCGCGAGTTTGAT
GGCCGAAGGCGAGGGGGTACTCACTTTCAATCATCTGCCGACACATCTTGCCCAAAAACTCAGCCACGCGGCGCCTACCG
CTACGGAGGATGATCAACAGAAAGACATCAAATCCACGGTAGAAGCATCCTTACTCAAGACCTACCAAGCAACGCAAGGC
AACATTAGCCAAACCTCGCGTTTGCTTGGGCTGAGCAGAAATACCATCTATCGCAAATTGAAAGCGCTGGGGATACTGAA
GTAA

Upstream 100 bases:

>100_bases
ATCGCAAGTAACAGACAAGGTTGCCGTACTCGATTGGATGATGTGTACGAGTGTTCAAGTGTTACAAAATGACACACCCA
GAGTGTGAGGAAATGGAACA

Downstream 100 bases:

>100_bases
GATTGGCGGCTTCACGTTACCAAGGGTGGGCGCAGCTTCATCGCCTATTCCCATTTTCTGCCTGATGAAAGGCAGATTTT
CACAGAGAACCCTCTAATGA

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MMQLQQLSHVNWLVNSWQRSEQAGLTQQSRAQDIRLSDNKLKERRQELAGLIDTVSRFALPLFYQLFAHSDSRLILTDQH
GVIIGSWGQARFREKLSQIALSSGACWQEPIKGTNAIGTALIEQKPISVIGEQHFIQHHHFISCSASPIFDYTGQLIGVL
DITSEQQKHTLSTQVVVQNMVQLVENQLLNQIPHGHVRIDLACEPSLLSSGWQGVIIADESGQILAHNQVAGQLLAQGRV
IGQSVEQVLPRPQTHASFIYTTTPLHSKQHRTRALTPASDLHFGDAEVERCWQQANRVIDKDIRLLILGQTGVGKNEFVK
ALHKNSQRKNGPLVAVNCGALAKELVEAELFGYVAGAFTGASHKGYQGKVRLADKGILFLDEIADLPLDAQSRLLHVLQD
KTVLPVGSNHATKVDIQIIAATHKNLEQLVTQGLFRQDLYYRLSDLVVELPSFQQRQDRQALIHHIHRRYSDAGQQICGD
LMQRLLAYHWPGNLRELDSLIKVASLMAEGEGVLTFNHLPTHLAQKLSHAAPTATEDDQQKDIKSTVEASLLKTYQATQG
NISQTSRLLGLSRNTIYRKLKALGILK

Sequences:

>Translated_587_residues
MMQLQQLSHVNWLVNSWQRSEQAGLTQQSRAQDIRLSDNKLKERRQELAGLIDTVSRFALPLFYQLFAHSDSRLILTDQH
GVIIGSWGQARFREKLSQIALSSGACWQEPIKGTNAIGTALIEQKPISVIGEQHFIQHHHFISCSASPIFDYTGQLIGVL
DITSEQQKHTLSTQVVVQNMVQLVENQLLNQIPHGHVRIDLACEPSLLSSGWQGVIIADESGQILAHNQVAGQLLAQGRV
IGQSVEQVLPRPQTHASFIYTTTPLHSKQHRTRALTPASDLHFGDAEVERCWQQANRVIDKDIRLLILGQTGVGKNEFVK
ALHKNSQRKNGPLVAVNCGALAKELVEAELFGYVAGAFTGASHKGYQGKVRLADKGILFLDEIADLPLDAQSRLLHVLQD
KTVLPVGSNHATKVDIQIIAATHKNLEQLVTQGLFRQDLYYRLSDLVVELPSFQQRQDRQALIHHIHRRYSDAGQQICGD
LMQRLLAYHWPGNLRELDSLIKVASLMAEGEGVLTFNHLPTHLAQKLSHAAPTATEDDQQKDIKSTVEASLLKTYQATQG
NISQTSRLLGLSRNTIYRKLKALGILK
>Mature_587_residues
MMQLQQLSHVNWLVNSWQRSEQAGLTQQSRAQDIRLSDNKLKERRQELAGLIDTVSRFALPLFYQLFAHSDSRLILTDQH
GVIIGSWGQARFREKLSQIALSSGACWQEPIKGTNAIGTALIEQKPISVIGEQHFIQHHHFISCSASPIFDYTGQLIGVL
DITSEQQKHTLSTQVVVQNMVQLVENQLLNQIPHGHVRIDLACEPSLLSSGWQGVIIADESGQILAHNQVAGQLLAQGRV
IGQSVEQVLPRPQTHASFIYTTTPLHSKQHRTRALTPASDLHFGDAEVERCWQQANRVIDKDIRLLILGQTGVGKNEFVK
ALHKNSQRKNGPLVAVNCGALAKELVEAELFGYVAGAFTGASHKGYQGKVRLADKGILFLDEIADLPLDAQSRLLHVLQD
KTVLPVGSNHATKVDIQIIAATHKNLEQLVTQGLFRQDLYYRLSDLVVELPSFQQRQDRQALIHHIHRRYSDAGQQICGD
LMQRLLAYHWPGNLRELDSLIKVASLMAEGEGVLTFNHLPTHLAQKLSHAAPTATEDDQQKDIKSTVEASLLKTYQATQG
NISQTSRLLGLSRNTIYRKLKALGILK

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=487, Percent_Identity=30.5954825462012, Blast_Score=208, Evalue=9e-55,
Organism=Escherichia coli, GI1788550, Length=290, Percent_Identity=37.2413793103448, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1788905, Length=315, Percent_Identity=36.1904761904762, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1790299, Length=334, Percent_Identity=37.125748502994, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1790437, Length=284, Percent_Identity=39.4366197183099, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI87082117, Length=327, Percent_Identity=34.5565749235474, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1789087, Length=304, Percent_Identity=35.8552631578947, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1786524, Length=298, Percent_Identity=37.248322147651, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI87081858, Length=599, Percent_Identity=27.0450751252087, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787583, Length=302, Percent_Identity=32.7814569536424, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87082152, Length=222, Percent_Identity=39.6396396396396, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI87081872, Length=312, Percent_Identity=31.0897435897436, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1789828, Length=220, Percent_Identity=36.3636363636364, Blast_Score=129, Evalue=6e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 65391; Mature: 65391

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQLQQLSHVNWLVNSWQRSEQAGLTQQSRAQDIRLSDNKLKERRQELAGLIDTVSRFAL
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PLFYQLFAHSDSRLILTDQHGVIIGSWGQARFREKLSQIALSSGACWQEPIKGTNAIGTA
HHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHH
LIEQKPISVIGEQHFIQHHHFISCSASPIFDYTGQLIGVLDITSEQQKHTLSTQVVVQNM
HHCCCCHHHHHHHHHHHHCCEEECCCCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
VQLVENQLLNQIPHGHVRIDLACEPSLLSSGWQGVIIADESGQILAHNQVAGQLLAQGRV
HHHHHHHHHHHCCCCCEEEEEEECCHHHHCCCCEEEEECCCCCEEECHHHHHHHHHHHHH
IGQSVEQVLPRPQTHASFIYTTTPLHSKQHRTRALTPASDLHFGDAEVERCWQQANRVID
HHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
KDIRLLILGQTGVGKNEFVKALHKNSQRKNGPLVAVNCGALAKELVEAELFGYVAGAFTG
CCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCC
ASHKGYQGKVRLADKGILFLDEIADLPLDAQSRLLHVLQDKTVLPVGSNHATKVDIQIIA
CCCCCCCCEEEEECCCCEEEHHHHCCCCCHHHHHHHHHHCCEEEECCCCCCEEEEEEEEE
ATHKNLEQLVTQGLFRQDLYYRLSDLVVELPSFQQRQDRQALIHHIHRRYSDAGQQICGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMQRLLAYHWPGNLRELDSLIKVASLMAEGEGVLTFNHLPTHLAQKLSHAAPTATEDDQQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCCCCHHH
KDIKSTVEASLLKTYQATQGNISQTSRLLGLSRNTIYRKLKALGILK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMQLQQLSHVNWLVNSWQRSEQAGLTQQSRAQDIRLSDNKLKERRQELAGLIDTVSRFAL
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PLFYQLFAHSDSRLILTDQHGVIIGSWGQARFREKLSQIALSSGACWQEPIKGTNAIGTA
HHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHH
LIEQKPISVIGEQHFIQHHHFISCSASPIFDYTGQLIGVLDITSEQQKHTLSTQVVVQNM
HHCCCCHHHHHHHHHHHHCCEEECCCCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
VQLVENQLLNQIPHGHVRIDLACEPSLLSSGWQGVIIADESGQILAHNQVAGQLLAQGRV
HHHHHHHHHHHCCCCCEEEEEEECCHHHHCCCCEEEEECCCCCEEECHHHHHHHHHHHHH
IGQSVEQVLPRPQTHASFIYTTTPLHSKQHRTRALTPASDLHFGDAEVERCWQQANRVID
HHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
KDIRLLILGQTGVGKNEFVKALHKNSQRKNGPLVAVNCGALAKELVEAELFGYVAGAFTG
CCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCC
ASHKGYQGKVRLADKGILFLDEIADLPLDAQSRLLHVLQDKTVLPVGSNHATKVDIQIIA
CCCCCCCCEEEEECCCCEEEHHHHCCCCCHHHHHHHHHHCCEEEECCCCCCEEEEEEEEE
ATHKNLEQLVTQGLFRQDLYYRLSDLVVELPSFQQRQDRQALIHHIHRRYSDAGQQICGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMQRLLAYHWPGNLRELDSLIKVASLMAEGEGVLTFNHLPTHLAQKLSHAAPTATEDDQQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCCCCHHH
KDIKSTVEASLLKTYQATQGNISQTSRLLGLSRNTIYRKLKALGILK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]