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The map label for this gene is trxB [H]

Identifier: 147674572

GI number: 147674572

Start: 814086

End: 815042

Strand: Reverse

Name: trxB [H]

Synonym: VC0395_A0803

Alternate gene names: 147674572

Gene position: 815042-814086 (Counterclockwise)

Preceding gene: 147673100

Following gene: 147675398

Centisome position: 26.95

GC content: 50.26

Gene sequence:

>957_bases
ATGAGTAACGTGAAACACAGCAAACTTCTTATCCTTGGCTCTGGCCCTGCGGGTTACACAGCCGCGGTTTACGCTGCGCG
CGCCAACCTAAAACCCGTGCTGGTCACTGGTATGCAGCAAGGTGGTCAGCTCACCACGACGACAGAAGTCGAGAACTGGC
CAGGCGATGCCGAAGGCTTAACTGGCCCAGCACTGATGGAGCGCATGAAAGAGCACGCTGAACGTTTCGATACTGAAATT
GTTTTTGATCACATTAACTCGGTTGATCTCTCTTCTCGCCCATTTCGTTTGACAGGCGACAGCCTAGAGTACACCTGTGA
TGCCCTCATCATCTCTACTGGTGCCTCTGCTAAATACCTCGGTTTAGAATCAGAAGAAGCGTTCAAAGGTCGCGGTGTAT
CCGCTTGTGCGACCTGTGATGGTTTCTTCTATCGCAACCAGAAAGTCGCCGTTGTCGGTGGTGGTAATACTGCGGTTGAA
GAGGCTCTTTACCTATCGAATATCGCCTCAGAAGTGCATCTGATCCACCGCCGTGACAGCTTCCGCAGTGAAAAAATTCT
GATCGATCGTCTGATGGATAAAGTGGCGAATGGCAACATTGTTCTGCACACGCACCGCACTTTGGATGAAGTACTGGGCG
ATGAGATGGGCGTGACAGGCGTGCGTTTGAAAGATACCCAGTCAGATATGACGGAAAACTTGGATGTGATGGGGGTATTC
ATTGCCATCGGTCATCAGCCAAACTCGCAAATTTTCGAAGGTCAGCTTGAAATGAAAAACGGCTACATTGTCGTAAAATC
TGGCCTTGAAGGTAATGCAACCCAGACCAGCATTGAAGGTGTGTTTGCCGCGGGTGATGTGATGGATCATAACTACCGTC
AAGCGATTACCTCTGCCGGAACCGGGTGTATGGCAGCACTCGATGCTGAACGTTACCTAGATAGCCAGGGTAAATAA

Upstream 100 bases:

>100_bases
ATATTCCCTACAATCGAGTCCAATTATTTTCATTGGCTTGCGTCTTAGTTCCGAATTCAAGCCATGAGTTAACTCCCTTT
CGTCCTTATCGGAGTACTTC

Downstream 100 bases:

>100_bases
CTTACGCTTCGCGTAACGACAGTTTTTATTTTTGCCAAGCCCGACGGGTATAACCGCCGGGCTTTTCTTTGTATACTGGC
GGCCTATTACAATTATTATT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGLTGPALMERMKEHAERFDTEI
VFDHINSVDLSSRPFRLTGDSLEYTCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIASEVHLIHRRDSFRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVF
IAIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDSQGK

Sequences:

>Translated_318_residues
MSNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGLTGPALMERMKEHAERFDTEI
VFDHINSVDLSSRPFRLTGDSLEYTCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIASEVHLIHRRDSFRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVF
IAIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDSQGK
>Mature_317_residues
SNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGLTGPALMERMKEHAERFDTEIV
FDHINSVDLSSRPFRLTGDSLEYTCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEE
ALYLSNIASEVHLIHRRDSFRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVFI
AIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDSQGK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=82.8571428571429, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=32.3717948717949, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321898, Length=328, Percent_Identity=46.6463414634146, Blast_Score=289, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6320560, Length=322, Percent_Identity=46.583850931677, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34345; Mature: 34214

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGL
CCCCCCEEEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPALMERMKEHAERFDTEIVFDHINSVDLSSRPFRLTGDSLEYTCDALIISTGASAKYL
CCHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIASEVHLIHRRDS
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
FRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCCEEEEECCHHHHHCCCCEEEEE
IAIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAG
EEECCCCCCCCEECEEEECCCEEEEECCCCCCCCHHHHCEEEEECCHHCCHHHHHHHHCC
TGCMAALDAERYLDSQGK
CCCEEHHHHHHHHCCCCC
>Mature Secondary Structure 
SNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGL
CCCCCEEEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPALMERMKEHAERFDTEIVFDHINSVDLSSRPFRLTGDSLEYTCDALIISTGASAKYL
CCHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIASEVHLIHRRDS
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
FRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCCEEEEECCHHHHHCCCCEEEEE
IAIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAG
EEECCCCCCCCEECEEEECCCEEEEECCCCCCCCHHHHCEEEEECCHHCCHHHHHHHHCC
TGCMAALDAERYLDSQGK
CCCEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]