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The map label for this gene is nrdR

Identifier: 147674568

GI number: 147674568

Start: 1979793

End: 1980242

Strand: Reverse

Name: nrdR

Synonym: VC0395_A1862

Alternate gene names: 147674568

Gene position: 1980242-1979793 (Counterclockwise)

Preceding gene: 147674854

Following gene: 147673692

Centisome position: 65.48

GC content: 48.0

Gene sequence:

>450_bases
ATGCATTGTCCTTTCTGTTCTGAAAACGATACCAAAGTGATCGATTCACGTCTGGTGGCTGACGGACATCAAGTGCGCCG
TCGTCGTCAGTGTCTGGCTTGTAATGAGCGCTTTACCACCTTTGAAACCGCGGAGTTAGTGATGCCACGCGTGATCAAAT
CGAATGGTAATCGTGAGCCTTTTGATGAAGAGAAAATGATTGGTGGCTTGCAGCGCGCATTGGAAAAGCGCCCAGTGAGT
GCCGATGCGATTGAACTGGCGATCAGCACCATAAAATCTAAGCTACGTGCCACTGGCGAGCGTGAAGTTCCGAGTAAACT
GATTGGTAACTTGGTGATGGAACAGCTGAAAGTGCTAGATAAAGTGGCCTATATTCGCTTTGCATCCGTATATCGTAGTT
TTGAAGATGTCCGTGAATTTGGCGAGGAGATCGCCAAACTGCAGGACTAA

Upstream 100 bases:

>100_bases
AAATTCAAGCAAAGATGTGATGTAAAGGGGCTTCGCGCCCCTTTTTCTTTGGCTCTCAACAGCACATCGGCTACACTGGT
TGTCTTGTTATGGAGGTAAT

Downstream 100 bases:

>100_bases
CCGATAGGATTAACTGAAAGCGATTATGCCTATGTTTACCTCTTTTGATCATCAAATGATGTCTCGCGCGATTGAACTTG
CGTGGCGCGGGCATTTTACC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREPFDEEKMIGGLQRALEKRPVS
ADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD

Sequences:

>Translated_149_residues
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREPFDEEKMIGGLQRALEKRPVS
ADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD
>Mature_149_residues
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREPFDEEKMIGGLQRALEKRPVS
ADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=79.1946308724832, Blast_Score=247, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_VIBC3 (A5F601)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- STRING:   A5F601
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1862
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   VCHO345073:VC0395_A1862-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17032; Mature: 17032

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREP
CCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
FDEEKMIGGLQRALEKRPVSADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLD
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDVREFGEEIAKLQD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREP
CCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
FDEEKMIGGLQRALEKRPVSADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLD
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDVREFGEEIAKLQD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA