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The map label for this gene is murR [H]

Identifier: 147674553

GI number: 147674553

Start: 2738842

End: 2739690

Strand: Reverse

Name: murR [H]

Synonym: VC0395_A2584

Alternate gene names: 147674553

Gene position: 2739690-2738842 (Counterclockwise)

Preceding gene: 147675088

Following gene: 147674646

Centisome position: 90.6

GC content: 52.77

Gene sequence:

>849_bases
ATGTCAGTTCTACAACGCATCGTCAGTCGCCGAACCCAACTTTCCGAGAGTGGCCGCCAAATTGGCGATTGGGTGATTGC
GAATGCACCTCAGGCGGCAGCGATGACCAGCCAAGATTTGGCGGCATGGGCCAATGTGAGCCAATCGAGTATAGTCAAAT
TCACCCAACGGCTTGGTTTTAAAGGCTACAGCGAATTTAAACTCGCCCTCACCGAAGAGCTGGGACGCAAACAAGTCATG
GTCAACCAGCCTTTACACAGCAACATCTTGGCCGATGACCCCGTTGCCGTGATTGCCCAAAAACTGGTGCAAACCAAAAC
CGAAGCGATGTTTCACACGACCAATGCCCTGCGTTTGGATGAGTTTAGTGAGGCGATCAGCTGGATTCAGCAAGCGGTGC
GGGTACAGATCATCGGGATTGGTGGCTCAGCACTGGTCGCCAAAGATCTCGCATTTAAGCTGCTCAAGCTCGGTATTACC
GCGCTCACGGAGCAAGATAGCCATGTGCAGATCGCGACCGCTCGCACCTTACATAGCCAAGATGTGCTGATTGCGATTTC
ATTTTCGGGAGAAAAGCGCGAAATTCTGATTGCAGCGGAAGCGGCCAAACAGCAAGGTGCGAAAGTGATTGCCCTGACCA
CACCGAACAAAAATCGCTTACGTGAGATAGCCGATCTGGCACTGGATACAATTGCCGATGAAACGCAGCACCGCAGCTCC
GCGATTGCTTCACGAACTGCGCAAAACGTGCTGACCGACCTGATTTTTCTCACCCTCACTCAGCAGCGTGAAACGTCCGC
GCGGCAGTTGATCGATGACATTTCTTCCGACATTCGCCAGATGCGTTGA

Upstream 100 bases:

>100_bases
AAAATAACCACGCAACCATGAAGTCATTGATTGAGAAAGAGTGAAGTGTGGCGTGCATTATTCCCATTTTGGAATATTTT
ATTCGCAAGGAGTGTGAAAA

Downstream 100 bases:

>100_bases
GAGGCGAACGCCTCTCAACTTCGGGTTTAGCGTGCACGCTGACTGAGTAACAGCAGCAGGAAATAGCTGCCACCAATGAT
TGCCACTAGCGTGCCTGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSVLQRIVSRRTQLSESGRQIGDWVIANAPQAAAMTSQDLAAWANVSQSSIVKFTQRLGFKGYSEFKLALTEELGRKQVM
VNQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLDEFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGIT
ALTEQDSHVQIATARTLHSQDVLIAISFSGEKREILIAAEAAKQQGAKVIALTTPNKNRLREIADLALDTIADETQHRSS
AIASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR

Sequences:

>Translated_282_residues
MSVLQRIVSRRTQLSESGRQIGDWVIANAPQAAAMTSQDLAAWANVSQSSIVKFTQRLGFKGYSEFKLALTEELGRKQVM
VNQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLDEFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGIT
ALTEQDSHVQIATARTLHSQDVLIAISFSGEKREILIAAEAAKQQGAKVIALTTPNKNRLREIADLALDTIADETQHRSS
AIASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR
>Mature_281_residues
SVLQRIVSRRTQLSESGRQIGDWVIANAPQAAAMTSQDLAAWANVSQSSIVKFTQRLGFKGYSEFKLALTEELGRKQVMV
NQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLDEFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGITA
LTEQDSHVQIATARTLHSQDVLIAISFSGEKREILIAAEAAKQQGAKVIALTTPNKNRLREIADLALDTIADETQHRSSA
IASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=274, Percent_Identity=40.8759124087591, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI87082130, Length=262, Percent_Identity=38.5496183206107, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI87082369, Length=252, Percent_Identity=25, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788159, Length=282, Percent_Identity=25.531914893617, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30997; Mature: 30866

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLQRIVSRRTQLSESGRQIGDWVIANAPQAAAMTSQDLAAWANVSQSSIVKFTQRLGF
CHHHHHHHHHHHHHHHCCHHHHCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KGYSEFKLALTEELGRKQVMVNQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLD
CCCHHHHHHHHHHCCCCCEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
EFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGITALTEQDSHVQIATARTLHSQ
HHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCC
DVLIAISFSGEKREILIAAEAAKQQGAKVIALTTPNKNRLREIADLALDTIADETQHRSS
CEEEEEEECCCCCEEEEEEHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AIASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVLQRIVSRRTQLSESGRQIGDWVIANAPQAAAMTSQDLAAWANVSQSSIVKFTQRLGF
HHHHHHHHHHHHHHHCCHHHHCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KGYSEFKLALTEELGRKQVMVNQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLD
CCCHHHHHHHHHHCCCCCEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
EFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGITALTEQDSHVQIATARTLHSQ
HHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCC
DVLIAISFSGEKREILIAAEAAKQQGAKVIALTTPNKNRLREIADLALDTIADETQHRSS
CEEEEEEECCCCCEEEEEEHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AIASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA