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The map label for this gene is exeA [H]

Identifier: 147674552

GI number: 147674552

Start: 2176803

End: 2178392

Strand: Reverse

Name: exeA [H]

Synonym: VC0395_A2023

Alternate gene names: 147674552

Gene position: 2178392-2176803 (Counterclockwise)

Preceding gene: 147675028

Following gene: 147675429

Centisome position: 72.04

GC content: 51.89

Gene sequence:

>1590_bases
ATGTATCTGAACTTCTTTGGGTTTGACGAACTACCGTTTTCTATCGTCCCCAATGCGCGTTATCTCTACCTGAGTCAGCG
TCATCAGGAAGCCATAGTACACCTGCAAGCCGGATTGGGCGATGGCGGCGGCTTTGCCATGCTCACCGGAGAAGTCGGGA
CGGGAAAAACCACTGTCGCGCGAGCGATTCTGGCGAGTTTGCCGGGCAAAACGCGCGCGGGGATGATCCTCAACCCCACT
TTTTCCGATTTGGAGCTATTGGAAGCGATTTGTGATGAATTTGAGGTCTGCTATCCGAAAAAAGCGACCTTAAAGAAACT
TACGCAAGTACTGCATGAGTTTTTGTTGGCCGAGCACGCGCAAGGCATACAAGTGCTTTTGATGATTGATGAAGCGCAGC
ATTTGGCACCGGATGTGTTGGAGCAGCTACGCCTGCTGACCAATTTGGAAACCGAGAGCCATAAACTGCTTAAAGTACTG
CTGATTGGCCAGCCCGAGTTGCAAGAAAAACTGCGTTTGCCGCAGTTGCGCCAGCTCGCCCAGCGGATCACTGGGCGCTA
CCATTTATTGCCATTGAATGAAGAGCAAACGGCCGACTACATCCGCTTTCGGATTGAGCAAGCCAGCGGTAACCCTGAGT
TGTTTAATCGTAAAGCCTGTCAGTGGATTGCAGAGCAAACTCACGGTATTCCGCGCTTAATCAATCTGGTGTGTGATGCG
GCGTTAAAGCAAGCGTATCAAGCGGGTGAACCAACGCTGAGCCTAGCGAGAATTAAGCTCGCCTGCCAAGAGGTGATGAG
CTTTCAATCTTCTGTTTATCAAGTGGCCTCGGCCAAACCTCCTGTACCTAAGCTCTCTTATCTCTCCAGCGCATTGGGGG
GGATAGCTCTGGCCGTCGTACTGACATGGCAGTTACCACCCCAGCTTGATCGGGTTATGCAACACTATTTTCCGTTACCT
GAAGTGGTGCCGCCGACCGAACAGAGAGTTTTCCCGCAAGCGTTACGTAGTGCGTTACTCAACGCGACGAGCAGCGAGCA
TGCCCTTGAAACTCTGTATGCGGTCTGGGGCTATCAAGCCTCGGTGCTGGAGCAGTTTTGCCAAACTCAAGCAGATGCGG
TGCTTTGGTGTGAAGAGCAGACGGGCGATTGGTCAACGCTACAAACTTACGATTTGCCCGCTGTACTCACTTTAATGATG
GATGATGTGCCCACTTACGCGGTGCTGTATCGCTTAACGGGCGATCAAGCGGAGCTGTTGGTGGGAGGCGAACGTTATCG
TATTGCCCGCCAATGGCTAGAGCCGTTATGGAATGGGCAATTTTCGCTACTTTGGCAGGCCAGTTTTTCTCGAACATTAA
AGCAGGGAATGCAGGGAGCCGATGTAGCCTTGCTCGAGAGCAAATTGGCGCAAGTGTTGGGCGAACCTGAACGCCCGCGT
GAGCAATTTGATAAGGATTTGTCGCGTAAAGTCGAGTTATTCCAACGTTGGCAGAACATGCACGTTGATGGTATCGCAGG
AAGACAAACCTTACGCCGCCTTGAGTTATTGACCCAACAGCAAGCGCCGAGTTTGAAGGAGGAAGGCTAA

Upstream 100 bases:

>100_bases
ATTTGCATCGTAGAGTCTCAAAAAATTGCATCAATGACATTGGCTAATCTTAGTCAGCAATGATACGTTGCACCCACTGC
GATGAATAGGGTCAACAAGC

Downstream 100 bases:

>100_bases
TGTCAAAAGTGATGAATGCCTTGAAGCAGTCTCAACAAAAGTATCTGCAAGCTCAGCCTGTCAGTCGTCGCACTTATACC
GAGCAAGAACCCACAGCGAT

Product: general secretion pathway protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MYLNFFGFDELPFSIVPNARYLYLSQRHQEAIVHLQAGLGDGGGFAMLTGEVGTGKTTVARAILASLPGKTRAGMILNPT
FSDLELLEAICDEFEVCYPKKATLKKLTQVLHEFLLAEHAQGIQVLLMIDEAQHLAPDVLEQLRLLTNLETESHKLLKVL
LIGQPELQEKLRLPQLRQLAQRITGRYHLLPLNEEQTADYIRFRIEQASGNPELFNRKACQWIAEQTHGIPRLINLVCDA
ALKQAYQAGEPTLSLARIKLACQEVMSFQSSVYQVASAKPPVPKLSYLSSALGGIALAVVLTWQLPPQLDRVMQHYFPLP
EVVPPTEQRVFPQALRSALLNATSSEHALETLYAVWGYQASVLEQFCQTQADAVLWCEEQTGDWSTLQTYDLPAVLTLMM
DDVPTYAVLYRLTGDQAELLVGGERYRIARQWLEPLWNGQFSLLWQASFSRTLKQGMQGADVALLESKLAQVLGEPERPR
EQFDKDLSRKVELFQRWQNMHVDGIAGRQTLRRLELLTQQQAPSLKEEG

Sequences:

>Translated_529_residues
MYLNFFGFDELPFSIVPNARYLYLSQRHQEAIVHLQAGLGDGGGFAMLTGEVGTGKTTVARAILASLPGKTRAGMILNPT
FSDLELLEAICDEFEVCYPKKATLKKLTQVLHEFLLAEHAQGIQVLLMIDEAQHLAPDVLEQLRLLTNLETESHKLLKVL
LIGQPELQEKLRLPQLRQLAQRITGRYHLLPLNEEQTADYIRFRIEQASGNPELFNRKACQWIAEQTHGIPRLINLVCDA
ALKQAYQAGEPTLSLARIKLACQEVMSFQSSVYQVASAKPPVPKLSYLSSALGGIALAVVLTWQLPPQLDRVMQHYFPLP
EVVPPTEQRVFPQALRSALLNATSSEHALETLYAVWGYQASVLEQFCQTQADAVLWCEEQTGDWSTLQTYDLPAVLTLMM
DDVPTYAVLYRLTGDQAELLVGGERYRIARQWLEPLWNGQFSLLWQASFSRTLKQGMQGADVALLESKLAQVLGEPERPR
EQFDKDLSRKVELFQRWQNMHVDGIAGRQTLRRLELLTQQQAPSLKEEG
>Mature_529_residues
MYLNFFGFDELPFSIVPNARYLYLSQRHQEAIVHLQAGLGDGGGFAMLTGEVGTGKTTVARAILASLPGKTRAGMILNPT
FSDLELLEAICDEFEVCYPKKATLKKLTQVLHEFLLAEHAQGIQVLLMIDEAQHLAPDVLEQLRLLTNLETESHKLLKVL
LIGQPELQEKLRLPQLRQLAQRITGRYHLLPLNEEQTADYIRFRIEQASGNPELFNRKACQWIAEQTHGIPRLINLVCDA
ALKQAYQAGEPTLSLARIKLACQEVMSFQSSVYQVASAKPPVPKLSYLSSALGGIALAVVLTWQLPPQLDRVMQHYFPLP
EVVPPTEQRVFPQALRSALLNATSSEHALETLYAVWGYQASVLEQFCQTQADAVLWCEEQTGDWSTLQTYDLPAVLTLMM
DDVPTYAVLYRLTGDQAELLVGGERYRIARQWLEPLWNGQFSLLWQASFSRTLKQGMQGADVALLESKLAQVLGEPERPR
EQFDKDLSRKVELFQRWQNMHVDGIAGRQTLRRLELLTQQQAPSLKEEG

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG3267

COG function: function code U; Type II secretory pathway, component ExeA (predicted ATPase)

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exeA family [H]

Homologues:

Organism=Escherichia coli, GI1789720, Length=249, Percent_Identity=23.6947791164659, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00004 AAA; PF01471 PG_binding_1 [H]

EC number: NA

Molecular weight: Translated: 59613; Mature: 59613

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLNFFGFDELPFSIVPNARYLYLSQRHQEAIVHLQAGLGDGGGFAMLTGEVGTGKTTVA
CEEEECCCCCCCCEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
RAILASLPGKTRAGMILNPTFSDLELLEAICDEFEVCYPKKATLKKLTQVLHEFLLAEHA
HHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
QGIQVLLMIDEAQHLAPDVLEQLRLLTNLETESHKLLKVLLIGQPELQEKLRLPQLRQLA
CCCEEEEEECCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHH
QRITGRYHLLPLNEEQTADYIRFRIEQASGNPELFNRKACQWIAEQTHGIPRLINLVCDA
HHHCCCEEEEECCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ALKQAYQAGEPTLSLARIKLACQEVMSFQSSVYQVASAKPPVPKLSYLSSALGGIALAVV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LTWQLPPQLDRVMQHYFPLPEVVPPTEQRVFPQALRSALLNATSSEHALETLYAVWGYQA
HHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHH
SVLEQFCQTQADAVLWCEEQTGDWSTLQTYDLPAVLTLMMDDVPTYAVLYRLTGDQAELL
HHHHHHHHCCCCEEEEEECCCCCCCCEECCCHHHHHHHHHHCCCHHHHHEEECCCCEEEE
VGGERYRIARQWLEPLWNGQFSLLWQASFSRTLKQGMQGADVALLESKLAQVLGEPERPR
ECCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHH
EQFDKDLSRKVELFQRWQNMHVDGIAGRQTLRRLELLTQQQAPSLKEEG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MYLNFFGFDELPFSIVPNARYLYLSQRHQEAIVHLQAGLGDGGGFAMLTGEVGTGKTTVA
CEEEECCCCCCCCEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
RAILASLPGKTRAGMILNPTFSDLELLEAICDEFEVCYPKKATLKKLTQVLHEFLLAEHA
HHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
QGIQVLLMIDEAQHLAPDVLEQLRLLTNLETESHKLLKVLLIGQPELQEKLRLPQLRQLA
CCCEEEEEECCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHH
QRITGRYHLLPLNEEQTADYIRFRIEQASGNPELFNRKACQWIAEQTHGIPRLINLVCDA
HHHCCCEEEEECCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ALKQAYQAGEPTLSLARIKLACQEVMSFQSSVYQVASAKPPVPKLSYLSSALGGIALAVV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LTWQLPPQLDRVMQHYFPLPEVVPPTEQRVFPQALRSALLNATSSEHALETLYAVWGYQA
HHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHH
SVLEQFCQTQADAVLWCEEQTGDWSTLQTYDLPAVLTLMMDDVPTYAVLYRLTGDQAELL
HHHHHHHHCCCCEEEEEECCCCCCCCEECCCHHHHHHHHHHCCCHHHHHEEECCCCEEEE
VGGERYRIARQWLEPLWNGQFSLLWQASFSRTLKQGMQGADVALLESKLAQVLGEPERPR
ECCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHH
EQFDKDLSRKVELFQRWQNMHVDGIAGRQTLRRLELLTQQQAPSLKEEG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961440 [H]