Click here to switch to the map view.

The map label for this gene is oxyR [H]

Identifier: 147674528

GI number: 147674528

Start: 2362162

End: 2363055

Strand: Reverse

Name: oxyR [H]

Synonym: VC0395_A2213

Alternate gene names: 147674528

Gene position: 2363055-2362162 (Counterclockwise)

Preceding gene: 147673344

Following gene: 147673687

Centisome position: 78.14

GC content: 49.66

Gene sequence:

>894_bases
ATGAACATTCGTGATTTTGAATACTTGGTCGCATTAGCTGACCACAAGCATTTCCGTAAAGCGGCAGAAGCGTGCTTTGT
CAGCCAACCCACCTTGAGTGGCCAGATCCGTAAGTTGGAAGATGAAATTGGAACGACTTTGCTTGAGCGCAGCAGTCGTC
GAGTTCTGTTTACCGAAGCGGGGCTACAACTGGTTGATCAGGCAAAGAAAATCCTTTCGGAAGTGAAAACGTTTAAAGAT
ATGGCTAACCAGCAAACCGGAGCCATGACTGGGCCGTTGCACATCGGCTTTATTCCGACCTTAGGGCCGTATTTACTGCC
GAAGATCATTCCTACTTTGAAAGAACGTTTCCCTGAATTGGAGCTGTATCTGCATGAAGCGCAGACTAACCAGTTAGTGC
GTCAGCTCGAAGAGGGCAAACTGGATTGCTTGGTGCTCGCTTCGGTGGAAGAGACGGCACCTTTTAAAGAAATTGAGCTG
TATAACGAAGTGTTGAGCATTGCAGTGCCTTGCGATCATGCTTGGGCGGCGCGTGACGAAGTGGACATGCTGGAGCTGAA
AGGTAAGACCGTATTGGCTTTAGGAGATGGGCATTGCCTGCGCGATCAAGCGTTAGGTTTTTGCTTTGCTGCGGGAGCGA
AAGATGATGAACGCTTTAAAGCCACCAGTTTAGAAACGTTGCGCAATATGGTGGCTGCAGGCGCGGGGATCACCTTATTG
CCTGAGCTAGCCTTACCTGAAGATAAAACCAAAGATGGGGTTTGTTACCTGCGGGCGGTTAACCCGATTCCATCGCGTCG
ACTCGTCTTGGCTTATCGACCAGGCTCGCCTTTACGCCAGCGGTTTGAGCAGTTGGCAGAAGTGATTAAACATCGCTTAC
AGCAAAGCGAGTAA

Upstream 100 bases:

>100_bases
GATGTGTTTCGTTGTTGATGGCTATTGTTAAAGAAAAGCTTTGATAGCTCTAATCGTTTAATGCTATGGTTTTAATAGAT
GCATTCTATCTGGGGAAGCT

Downstream 100 bases:

>100_bases
GACGGCGAATCGAATACAAAAAAGAGGCTGATGATTCAGCCTCTTTTTATTCGGTTTTCTGTACCAGAGTTTACTAGAAC
AGCTCTTCACCAGAGCTGGT

Product: DNA-binding transcriptional regulator OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNIRDFEYLVALADHKHFRKAAEACFVSQPTLSGQIRKLEDEIGTTLLERSSRRVLFTEAGLQLVDQAKKILSEVKTFKD
MANQQTGAMTGPLHIGFIPTLGPYLLPKIIPTLKERFPELELYLHEAQTNQLVRQLEEGKLDCLVLASVEETAPFKEIEL
YNEVLSIAVPCDHAWAARDEVDMLELKGKTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
PELALPEDKTKDGVCYLRAVNPIPSRRLVLAYRPGSPLRQRFEQLAEVIKHRLQQSE

Sequences:

>Translated_297_residues
MNIRDFEYLVALADHKHFRKAAEACFVSQPTLSGQIRKLEDEIGTTLLERSSRRVLFTEAGLQLVDQAKKILSEVKTFKD
MANQQTGAMTGPLHIGFIPTLGPYLLPKIIPTLKERFPELELYLHEAQTNQLVRQLEEGKLDCLVLASVEETAPFKEIEL
YNEVLSIAVPCDHAWAARDEVDMLELKGKTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
PELALPEDKTKDGVCYLRAVNPIPSRRLVLAYRPGSPLRQRFEQLAEVIKHRLQQSE
>Mature_297_residues
MNIRDFEYLVALADHKHFRKAAEACFVSQPTLSGQIRKLEDEIGTTLLERSSRRVLFTEAGLQLVDQAKKILSEVKTFKD
MANQQTGAMTGPLHIGFIPTLGPYLLPKIIPTLKERFPELELYLHEAQTNQLVRQLEEGKLDCLVLASVEETAPFKEIEL
YNEVLSIAVPCDHAWAARDEVDMLELKGKTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
PELALPEDKTKDGVCYLRAVNPIPSRRLVLAYRPGSPLRQRFEQLAEVIKHRLQQSE

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=64.1638225255973, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1788887, Length=296, Percent_Identity=27.7027027027027, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI157672245, Length=276, Percent_Identity=27.536231884058, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=26, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787879, Length=256, Percent_Identity=30.859375, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788748, Length=301, Percent_Identity=25.9136212624585, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=26.7605633802817, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790208, Length=253, Percent_Identity=30.4347826086957, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=28.2258064516129, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI2367136, Length=244, Percent_Identity=24.1803278688525, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=26.8965517241379, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788296, Length=229, Percent_Identity=26.2008733624454, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788626, Length=290, Percent_Identity=26.551724137931, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786401, Length=259, Percent_Identity=23.1660231660232, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33236; Mature: 33236

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRDFEYLVALADHKHFRKAAEACFVSQPTLSGQIRKLEDEIGTTLLERSSRRVLFTEA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHH
GLQLVDQAKKILSEVKTFKDMANQQTGAMTGPLHIGFIPTLGPYLLPKIIPTLKERFPEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHH
ELYLHEAQTNQLVRQLEEGKLDCLVLASVEETAPFKEIELYNEVLSIAVPCDHAWAARDE
EEHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC
VDMLELKGKTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
CHHHEECCCEEEEECCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEC
PELALPEDKTKDGVCYLRAVNPIPSRRLVLAYRPGSPLRQRFEQLAEVIKHRLQQSE
CCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIRDFEYLVALADHKHFRKAAEACFVSQPTLSGQIRKLEDEIGTTLLERSSRRVLFTEA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHH
GLQLVDQAKKILSEVKTFKDMANQQTGAMTGPLHIGFIPTLGPYLLPKIIPTLKERFPEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHH
ELYLHEAQTNQLVRQLEEGKLDCLVLASVEETAPFKEIELYNEVLSIAVPCDHAWAARDE
EEHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC
VDMLELKGKTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
CHHHEECCCEEEEECCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEC
PELALPEDKTKDGVCYLRAVNPIPSRRLVLAYRPGSPLRQRFEQLAEVIKHRLQQSE
CCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA