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The map label for this gene is msrB

Identifier: 147674517

GI number: 147674517

Start: 1704615

End: 1705058

Strand: Reverse

Name: msrB

Synonym: VC0395_A1584

Alternate gene names: 147674517

Gene position: 1705058-1704615 (Counterclockwise)

Preceding gene: 147674465

Following gene: 147673659

Centisome position: 56.38

GC content: 44.37

Gene sequence:

>444_bases
ATGGTCAGTGAAGCGATAAGTAAAAAGGAAATAGAAAGGGTGAAATTCGAATCAAAAGATCTGCACAAGCCTGATGAATA
CTGGCGTGAGCACCTGACGGAAGAGGCGTTTTATGTCTGCCGCCAACAGGGGACAGAAGCACCATACTCAGGTAAGTTGT
TACACAATAAAGACACGGGTCTTTACCACTGTACCTGTTGCCAAAGCGCTCTGTTTAGCTCTGAAAATAAATACGATTCG
GGCTGCGGTTGGCCAAGTTTTGATGCGCCGATTAATGAACAGGTGATACGCTTTTTGGATGACTTTAGTCACGGAATGGT
GCGTACCGAAATTCGTTGTGCAGCCTGTGATAGCCACCTTGGACATGTTTTTGAAGACGGTCCTAAGACGACAGGATTGA
GATTTTGTGTTAACTCGGTGTCGTTAATTTTCAACAAAAAGTGA

Upstream 100 bases:

>100_bases
TGGCGATGGTTAAGTACCGCACACACTAAAAAATCTTGCTCAAAATAGAGTGAAAAAGTATGTGCCACAAACTCTGAATT
AGGCAAGTTTTTCACAAAAA

Downstream 100 bases:

>100_bases
ATATTGCCAGACGACTTGGAGTGTTAGGTGGGTGCCAAGTGAGTTCATCCCCGAGCACCAATAGGTTATGCGATGGGAAA
TAACCGCCGTCAACAGCGCT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MVSEAISKKEIERVKFESKDLHKPDEYWREHLTEEAFYVCRQQGTEAPYSGKLLHNKDTGLYHCTCCQSALFSSENKYDS
GCGWPSFDAPINEQVIRFLDDFSHGMVRTEIRCAACDSHLGHVFEDGPKTTGLRFCVNSVSLIFNKK

Sequences:

>Translated_147_residues
MVSEAISKKEIERVKFESKDLHKPDEYWREHLTEEAFYVCRQQGTEAPYSGKLLHNKDTGLYHCTCCQSALFSSENKYDS
GCGWPSFDAPINEQVIRFLDDFSHGMVRTEIRCAACDSHLGHVFEDGPKTTGLRFCVNSVSLIFNKK
>Mature_147_residues
MVSEAISKKEIERVKFESKDLHKPDEYWREHLTEEAFYVCRQQGTEAPYSGKLLHNKDTGLYHCTCCQSALFSSENKYDS
GCGWPSFDAPINEQVIRFLDDFSHGMVRTEIRCAACDSHLGHVFEDGPKTTGLRFCVNSVSLIFNKK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI37620216, Length=117, Percent_Identity=49.5726495726496, Blast_Score=137, Evalue=5e-33,
Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=51.5625, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI301336164, Length=117, Percent_Identity=49.5726495726496, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI301336162, Length=117, Percent_Identity=49.5726495726496, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI73089054, Length=117, Percent_Identity=49.5726495726496, Blast_Score=136, Evalue=6e-33,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=58.8235294117647, Blast_Score=161, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17553450, Length=150, Percent_Identity=44, Blast_Score=129, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=150, Percent_Identity=44, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319816, Length=130, Percent_Identity=41.5384615384615, Blast_Score=99, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221378664, Length=122, Percent_Identity=45.9016393442623, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24645799, Length=120, Percent_Identity=45.8333333333333, Blast_Score=119, Evalue=8e-28,
Organism=Drosophila melanogaster, GI45553335, Length=120, Percent_Identity=45.8333333333333, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356369, Length=120, Percent_Identity=45.8333333333333, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221378662, Length=129, Percent_Identity=43.4108527131783, Blast_Score=116, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24645801, Length=131, Percent_Identity=41.9847328244275, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24645804, Length=131, Percent_Identity=41.9847328244275, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_VIBC3 (A5F6R2)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F6R2
- SMR:   A5F6R2
- STRING:   A5F6R2
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1584
- eggNOG:   COG0229
- HOGENOM:   HBG715255
- OMA:   CINSICL
- ProtClustDB:   PRK00222
- BioCyc:   VCHO345073:VC0395_A1584-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 16819; Mature: 16819

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: ACT_SITE 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSEAISKKEIERVKFESKDLHKPDEYWREHLTEEAFYVCRQQGTEAPYSGKLLHNKDTG
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
LYHCTCCQSALFSSENKYDSGCGWPSFDAPINEQVIRFLDDFSHGMVRTEIRCAACDSHL
EEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GHVFEDGPKTTGLRFCVNSVSLIFNKK
HHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSEAISKKEIERVKFESKDLHKPDEYWREHLTEEAFYVCRQQGTEAPYSGKLLHNKDTG
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
LYHCTCCQSALFSSENKYDSGCGWPSFDAPINEQVIRFLDDFSHGMVRTEIRCAACDSHL
EEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GHVFEDGPKTTGLRFCVNSVSLIFNKK
HHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA