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The map label for this gene is hscA [H]

Identifier: 147674259

GI number: 147674259

Start: 1024835

End: 1026376

Strand: Reverse

Name: hscA [H]

Synonym: VC0395_A0987

Alternate gene names: 147674259

Gene position: 1026376-1024835 (Counterclockwise)

Preceding gene: 147674035

Following gene: 147675195

Centisome position: 33.94

GC content: 53.05

Gene sequence:

>1542_bases
TTGCCATCGGGCAGCCCTGAAGATGTCAGCAAAATTTCCCCTCTGCGTGCCACTGAACTTTATTTAGAGCACTTACAAGC
CGCGTGGGATCATGCGCATCCTGATGCCCCATTAGCTGAACAAGATGTCACCATTACCGTTCCTGCTTCGTTTGATCCTG
CCGCCCGTGATTTAACCGCGGAAGCGGCACGTAATATTGGCCTGCAGCACTTTACTCTGCTCGAAGAACCACAAGCGGCG
CTGTACAGCTGGATTGATAACCGCCATGAGCAATGGCGCAGTGAAGTGAGCGTTGGCGATGTGGTGTTAGTGATCGATAT
CGGCGGCGGTACCACTGACCTCTCACTGGTCGAAGTGACCGAAGAAGAAGGCAACCTTGCCCTCAAGCGTATTGCCGTTG
GCGAACATATTCTGCTCGGTGGCGATAACATGGATCTCGCCCTCGCCTATCGTCTGAAAATGAAGTTGGCGCAGGAAGGC
AAAGAGCTGCAAATGTGGCAAGTACAAGCCATGACACACGCATGCCGTGATGCAAAAGAAGTACTCCTCAGCCAACCGGA
TTTGGCCGCAGTGCCGATCGTGGTACCAAGCCGCGGTTCTAAACTGCTCGGCGCAACACTGAAAACCGAACTGACTCGTG
AAGAAGTTCAGCAAACGCTAGTCGATGGTTTCTTCCCAGCAGTTTCTATCAACGAACATCCACAACACAAAATGCGCGGC
GCACTGACTCAGATGAGTTTGCCTTACGCGCAAGATGCCGGCATCACTCGCCACATCGCCGCATTTTTAAGTAAACAAGC
CAACGCGCAAGGTCAAACCGAAAGCCTGCCTTTCGCGATGGCCGGCATTCCGGGCATGGCCGCTCCACAAGCCGATTTCA
TTAAGCCAAGTGCCATTTTACTTAACGGCGGTGTGCTTAAATCGACTCTGCTTGCCGATCGTTTGCTAGAAACCATCAAT
GCTTGGTTAACTCAGGCCAATGCGGCTCCTGCCAAACTCCTTGCCGGAGTGGATTTGGATCTGGCAGTGGCACGTGGCGC
GGCTTACTACGGCGTTGTGCGTCAAGGTCAAGGGATACGCATCCGTGGTGGTATTGCTTCGGCTTACTATGTCGGGATTG
AAAGTGCGATGCCAGCCATTCCGGGCATGTTACCGCCGATGGAAGCACTCTGCGTTGCTCCATTTGGTATGGAAGAAGGC
TCGAGCGCGCAAGTCGCGGATCGCCAGTTTGGCCTAGTGATTGGTGAGCCAGTGCACTTCCAATTCTATGGCTCCACCGT
TCGCCGTGATGATGTTGCGGGGACTCACCTTGTCGATTGGGCCAATGATGAACTAGACGATCTGCCAACCATTCAGATCA
CCTTACCTGTTTCTGAAGGTCGCCGAGCAGGAGAAGTGGTTCCGGTTACGCTGGCATCACGAGTGACTGAGCTCGGTACG
CTCTATCTTGAAGCGATTGCGGCTGATAATGGCCAAAAATGGCATGTGGAATTTGATGTTCGGGATAACCCACAGAACGA
ACCTACACCACAGCAACATTAA

Upstream 100 bases:

>100_bases
TGCAATTGCGCGTAATTTGGGCTCAAAAACCCCGATTCGCCTAGTCGCAAGCGCCAAATCTTGATTATGCCATGCGGGCG
TTAATCGTCGCGAAGCCTTT

Downstream 100 bases:

>100_bases
CAAGACAGTAGCGGCATCCTTCGGGGTGCCGCTCAACCTTTATGAACACGAGGTATCGCATGTCATCACCACGTTTTCTG
GTCGGCATTGATTTAGGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MPSGSPEDVSKISPLRATELYLEHLQAAWDHAHPDAPLAEQDVTITVPASFDPAARDLTAEAARNIGLQHFTLLEEPQAA
LYSWIDNRHEQWRSEVSVGDVVLVIDIGGGTTDLSLVEVTEEEGNLALKRIAVGEHILLGGDNMDLALAYRLKMKLAQEG
KELQMWQVQAMTHACRDAKEVLLSQPDLAAVPIVVPSRGSKLLGATLKTELTREEVQQTLVDGFFPAVSINEHPQHKMRG
ALTQMSLPYAQDAGITRHIAAFLSKQANAQGQTESLPFAMAGIPGMAAPQADFIKPSAILLNGGVLKSTLLADRLLETIN
AWLTQANAAPAKLLAGVDLDLAVARGAAYYGVVRQGQGIRIRGGIASAYYVGIESAMPAIPGMLPPMEALCVAPFGMEEG
SSAQVADRQFGLVIGEPVHFQFYGSTVRRDDVAGTHLVDWANDELDDLPTIQITLPVSEGRRAGEVVPVTLASRVTELGT
LYLEAIAADNGQKWHVEFDVRDNPQNEPTPQQH

Sequences:

>Translated_513_residues
MPSGSPEDVSKISPLRATELYLEHLQAAWDHAHPDAPLAEQDVTITVPASFDPAARDLTAEAARNIGLQHFTLLEEPQAA
LYSWIDNRHEQWRSEVSVGDVVLVIDIGGGTTDLSLVEVTEEEGNLALKRIAVGEHILLGGDNMDLALAYRLKMKLAQEG
KELQMWQVQAMTHACRDAKEVLLSQPDLAAVPIVVPSRGSKLLGATLKTELTREEVQQTLVDGFFPAVSINEHPQHKMRG
ALTQMSLPYAQDAGITRHIAAFLSKQANAQGQTESLPFAMAGIPGMAAPQADFIKPSAILLNGGVLKSTLLADRLLETIN
AWLTQANAAPAKLLAGVDLDLAVARGAAYYGVVRQGQGIRIRGGIASAYYVGIESAMPAIPGMLPPMEALCVAPFGMEEG
SSAQVADRQFGLVIGEPVHFQFYGSTVRRDDVAGTHLVDWANDELDDLPTIQITLPVSEGRRAGEVVPVTLASRVTELGT
LYLEAIAADNGQKWHVEFDVRDNPQNEPTPQQH
>Mature_512_residues
PSGSPEDVSKISPLRATELYLEHLQAAWDHAHPDAPLAEQDVTITVPASFDPAARDLTAEAARNIGLQHFTLLEEPQAAL
YSWIDNRHEQWRSEVSVGDVVLVIDIGGGTTDLSLVEVTEEEGNLALKRIAVGEHILLGGDNMDLALAYRLKMKLAQEGK
ELQMWQVQAMTHACRDAKEVLLSQPDLAAVPIVVPSRGSKLLGATLKTELTREEVQQTLVDGFFPAVSINEHPQHKMRGA
LTQMSLPYAQDAGITRHIAAFLSKQANAQGQTESLPFAMAGIPGMAAPQADFIKPSAILLNGGVLKSTLLADRLLETINA
WLTQANAAPAKLLAGVDLDLAVARGAAYYGVVRQGQGIRIRGGIASAYYVGIESAMPAIPGMLPPMEALCVAPFGMEEGS
SAQVADRQFGLVIGEPVHFQFYGSTVRRDDVAGTHLVDWANDELDDLPTIQITLPVSEGRRAGEVVPVTLASRVTELGTL
YLEAIAADNGQKWHVEFDVRDNPQNEPTPQQH

Specific function: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by hscB [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126
- InterPro:   IPR010236 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 55359; Mature: 55227

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSGSPEDVSKISPLRATELYLEHLQAAWDHAHPDAPLAEQDVTITVPASFDPAARDLTA
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
EAARNIGLQHFTLLEEPQAALYSWIDNRHEQWRSEVSVGDVVLVIDIGGGTTDLSLVEVT
HHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEE
EEEGNLALKRIAVGEHILLGGDNMDLALAYRLKMKLAQEGKELQMWQVQAMTHACRDAKE
CCCCCEEEEEEECCCEEEECCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VLLSQPDLAAVPIVVPSRGSKLLGATLKTELTREEVQQTLVDGFFPAVSINEHPQHKMRG
HHHCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHH
ALTQMSLPYAQDAGITRHIAAFLSKQANAQGQTESLPFAMAGIPGMAAPQADFIKPSAIL
HHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEE
LNGGVLKSTLLADRLLETINAWLTQANAAPAKLLAGVDLDLAVARGAAYYGVVRQGQGIR
EECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCCCEEHEEECCCCEE
IRGGIASAYYVGIESAMPAIPGMLPPMEALCVAPFGMEEGSSAQVADRQFGLVIGEPVHF
EECCCCEEEEEEHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCEEE
QFYGSTVRRDDVAGTHLVDWANDELDDLPTIQITLPVSEGRRAGEVVPVTLASRVTELGT
EEECCEECCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHH
LYLEAIAADNGQKWHVEFDVRDNPQNEPTPQQH
HHHHEEECCCCCEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
PSGSPEDVSKISPLRATELYLEHLQAAWDHAHPDAPLAEQDVTITVPASFDPAARDLTA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
EAARNIGLQHFTLLEEPQAALYSWIDNRHEQWRSEVSVGDVVLVIDIGGGTTDLSLVEVT
HHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEE
EEEGNLALKRIAVGEHILLGGDNMDLALAYRLKMKLAQEGKELQMWQVQAMTHACRDAKE
CCCCCEEEEEEECCCEEEECCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VLLSQPDLAAVPIVVPSRGSKLLGATLKTELTREEVQQTLVDGFFPAVSINEHPQHKMRG
HHHCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHH
ALTQMSLPYAQDAGITRHIAAFLSKQANAQGQTESLPFAMAGIPGMAAPQADFIKPSAIL
HHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEE
LNGGVLKSTLLADRLLETINAWLTQANAAPAKLLAGVDLDLAVARGAAYYGVVRQGQGIR
EECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCCCEEHEEECCCCEE
IRGGIASAYYVGIESAMPAIPGMLPPMEALCVAPFGMEEGSSAQVADRQFGLVIGEPVHF
EECCCCEEEEEEHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCEEE
QFYGSTVRRDDVAGTHLVDWANDELDDLPTIQITLPVSEGRRAGEVVPVTLASRVTELGT
EEECCEECCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHH
LYLEAIAADNGQKWHVEFDVRDNPQNEPTPQQH
HHHHEEECCCCCEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA