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The map label for this gene is tlpB [H]

Identifier: 147673937

GI number: 147673937

Start: 1052350

End: 1054275

Strand: Reverse

Name: tlpB [H]

Synonym: VC0395_A1015

Alternate gene names: 147673937

Gene position: 1054275-1052350 (Counterclockwise)

Preceding gene: 147674524

Following gene: 147674323

Centisome position: 34.86

GC content: 44.86

Gene sequence:

>1926_bases
ATGGCGCTCAAGAAACATATCACTACCAGTGCTAGCTCATCATTTAGTCCGAGCAACCATAGCACTTCGGCTAATGCCCC
CAAAAAAGAAGCTGATGATTTGCGTCGCCAAGCAAGAACATTAGCCAGAAAACAACAAGCTGCCGAACGAGTGGCTTCTG
CTACAGCAGAATTATTGGCTGGATTAGAAGAAAGTTCTTCTGCCATGACTCAACTACGTAGCTCTATGGAACAGATTGCG
GTGGGTGCGGAAGAATCTTCATCGGCTACAAAACAAAGTGAAACGGCGGTATCACAGATGAATAACTTCATCAATGAACA
AGCCACCTATGCCACTCAATCTAAGCAAATTTTGACTAAACTCGAACAAGATATTGTTGATGTGGCTAATAAAATCAATG
AGATGGTATCGAACGTCCAAACCTCTTCAGAACGACAAAACGATTCGGTCAAACGAATGATCGAACTTTCCGAACAAGCA
GCCAAAATTAATGATGCAGTGAAACAAGTCATACATATCGCGGATCAAACTAACTTATTGGCGTTGAATGCGGCGATTGA
AGCGGGTCGTGCAGGTAAACATGGGAAAGGGTTTGCGGTGGTGGCCGATACAGTTAGAACCTTAGCTGAGAAGGCCGAAA
AAAATGCGGCCAACATTGAAAGTCTCATCAAGGACATTTCTAACGGTGCGGAAATGGTTTCAAACGGAGTGAAATCAAGC
TCTCAAAAAGCAGAAAGTGAAGTTCAGAAAGGCCATGTCGTCAATAAACAACTTACGCTCATTCGCAATGAAATGGTTGA
TTTAGTGAAAGATTCAGAAGTGTTATTGAAAGCTGCGGATGAGATGTCTTCTGCAGCAGTTATTGCCTTAAAAGGTTCCG
AATCTGTCTCACAAGCCGCTCAAGAACAGTCGGCCGCCTGTGAAGAGAGCTTAAAAAGTCTAGATCAACAACAAATCGCG
CTTGATGGTGCTGTCACAGCAGCTCAGTCACTTGATGAATTAACCGATGAGCTACGCACATCCACCGATATCGTTAAATC
ATCTGAAGAAGTCGCTGCCGCTGCCGAAGAGCTCTCTGCTGGCATTGAAGAGATCAACCGCTCATCGAATGAAATTATGG
GTGCACTCAACCAGATCAGCTCTGGTGCACAACATATGGCCAAGTCGGTTGAAACCGGGATCACTAGCTTAACGCAGATA
GAACAAGGAGCTCGCCTTGGTAAAGAACGCGCAGAAAGCAGCCTGAAAGCTTGCGAGAAAATGTTGACAGGTATAGAAGA
AAACAAAACTACTGTTGACGAGATGATCTTAGCCATTACGGAATCTACCAAAGCTGCAACGGAAAATCTGAATGAAATGG
CGAATATTGAACGTATTTCGCGACAGATCGATAAAATCGTCGATGGTATTTCCAATGTCTCCATTCAAACCGCCATGTTG
GCTGTGAATGGTGCTGTCGAGGCAGCACGCGCAGGTGAATATGGAAAAGGTTTTGCTGTTGTTTCTACCGATATTCAAAA
CCTCGCCAACGATGCTGCTGAAAACGCTGAACAAATCAAAGATCAAGTTAAGAATATCCAAGAGCAAATCAACATTGTTC
GTAAAGATTTAGCTGACATCCTTTCGACAGTGATGGAAGAGGCTCAAAAAGCAGCTCTGACCATCAAACAACTGGATAAT
GTTCGCTCTAGGATGAGTGATGTGGTGTTAGGAAGTAAACGTATTTCTGAAAGTGCCGAGGGCATCGAGCGTTCGATTGC
TGATGCACGCGCGGGAATGCAACAAATTGCCACTGCAGCCGAAGAATCCTCTCATGCAACGGGTGAAGCCGCTACTGCGG
CTCGTCAGCAAAGCTCAAGTACTTCGGAGCTGGCATCCGCAATTGAAAATATTGCCGCCGTTGCCGATGAACTTCAATCA
ATCTGA

Upstream 100 bases:

>100_bases
ATTTAAATCATTGTCTATACTGATCTAACATCTTGGATGAATATCTCATTTTGGAGATGGATTACATCTGTTACATCAAT
GGCAAACAACGAGGTTTTCC

Downstream 100 bases:

>100_bases
TTGAGGTGAACTATGACCAGTGAAGCCCTTGTAGACAACGAACTTGAGCATGAAGAGAACCTCACACAGTATGTCAATTT
CATGCTGGGTGATGAGCTTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MALKKHITTSASSSFSPSNHSTSANAPKKEADDLRRQARTLARKQQAAERVASATAELLAGLEESSSAMTQLRSSMEQIA
VGAEESSSATKQSETAVSQMNNFINEQATYATQSKQILTKLEQDIVDVANKINEMVSNVQTSSERQNDSVKRMIELSEQA
AKINDAVKQVIHIADQTNLLALNAAIEAGRAGKHGKGFAVVADTVRTLAEKAEKNAANIESLIKDISNGAEMVSNGVKSS
SQKAESEVQKGHVVNKQLTLIRNEMVDLVKDSEVLLKAADEMSSAAVIALKGSESVSQAAQEQSAACEESLKSLDQQQIA
LDGAVTAAQSLDELTDELRTSTDIVKSSEEVAAAAEELSAGIEEINRSSNEIMGALNQISSGAQHMAKSVETGITSLTQI
EQGARLGKERAESSLKACEKMLTGIEENKTTVDEMILAITESTKAATENLNEMANIERISRQIDKIVDGISNVSIQTAML
AVNGAVEAARAGEYGKGFAVVSTDIQNLANDAAENAEQIKDQVKNIQEQINIVRKDLADILSTVMEEAQKAALTIKQLDN
VRSRMSDVVLGSKRISESAEGIERSIADARAGMQQIATAAEESSHATGEAATAARQQSSSTSELASAIENIAAVADELQS
I

Sequences:

>Translated_641_residues
MALKKHITTSASSSFSPSNHSTSANAPKKEADDLRRQARTLARKQQAAERVASATAELLAGLEESSSAMTQLRSSMEQIA
VGAEESSSATKQSETAVSQMNNFINEQATYATQSKQILTKLEQDIVDVANKINEMVSNVQTSSERQNDSVKRMIELSEQA
AKINDAVKQVIHIADQTNLLALNAAIEAGRAGKHGKGFAVVADTVRTLAEKAEKNAANIESLIKDISNGAEMVSNGVKSS
SQKAESEVQKGHVVNKQLTLIRNEMVDLVKDSEVLLKAADEMSSAAVIALKGSESVSQAAQEQSAACEESLKSLDQQQIA
LDGAVTAAQSLDELTDELRTSTDIVKSSEEVAAAAEELSAGIEEINRSSNEIMGALNQISSGAQHMAKSVETGITSLTQI
EQGARLGKERAESSLKACEKMLTGIEENKTTVDEMILAITESTKAATENLNEMANIERISRQIDKIVDGISNVSIQTAML
AVNGAVEAARAGEYGKGFAVVSTDIQNLANDAAENAEQIKDQVKNIQEQINIVRKDLADILSTVMEEAQKAALTIKQLDN
VRSRMSDVVLGSKRISESAEGIERSIADARAGMQQIATAAEESSHATGEAATAARQQSSSTSELASAIENIAAVADELQS
I
>Mature_640_residues
ALKKHITTSASSSFSPSNHSTSANAPKKEADDLRRQARTLARKQQAAERVASATAELLAGLEESSSAMTQLRSSMEQIAV
GAEESSSATKQSETAVSQMNNFINEQATYATQSKQILTKLEQDIVDVANKINEMVSNVQTSSERQNDSVKRMIELSEQAA
KINDAVKQVIHIADQTNLLALNAAIEAGRAGKHGKGFAVVADTVRTLAEKAEKNAANIESLIKDISNGAEMVSNGVKSSS
QKAESEVQKGHVVNKQLTLIRNEMVDLVKDSEVLLKAADEMSSAAVIALKGSESVSQAAQEQSAACEESLKSLDQQQIAL
DGAVTAAQSLDELTDELRTSTDIVKSSEEVAAAAEELSAGIEEINRSSNEIMGALNQISSGAQHMAKSVETGITSLTQIE
QGARLGKERAESSLKACEKMLTGIEENKTTVDEMILAITESTKAATENLNEMANIERISRQIDKIVDGISNVSIQTAMLA
VNGAVEAARAGEYGKGFAVVSTDIQNLANDAAENAEQIKDQVKNIQEQINIVRKDLADILSTVMEEAQKAALTIKQLDNV
RSRMSDVVLGSKRISESAEGIERSIADARAGMQQIATAAEESSHATGEAATAARQQSSSTSELASAIENIAAVADELQSI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=168, Percent_Identity=37.5, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI2367378, Length=187, Percent_Identity=34.7593582887701, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787690, Length=186, Percent_Identity=34.4086021505376, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788194, Length=117, Percent_Identity=38.4615384615385, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789453, Length=242, Percent_Identity=29.7520661157025, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 68117; Mature: 67985

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKKHITTSASSSFSPSNHSTSANAPKKEADDLRRQARTLARKQQAAERVASATAELLA
CCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLEESSSAMTQLRSSMEQIAVGAEESSSATKQSETAVSQMNNFINEQATYATQSKQILTK
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQDIVDVANKINEMVSNVQTSSERQNDSVKRMIELSEQAAKINDAVKQVIHIADQTNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ALNAAIEAGRAGKHGKGFAVVADTVRTLAEKAEKNAANIESLIKDISNGAEMVSNGVKSS
EHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCH
SQKAESEVQKGHVVNKQLTLIRNEMVDLVKDSEVLLKAADEMSSAAVIALKGSESVSQAA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
QEQSAACEESLKSLDQQQIALDGAVTAAQSLDELTDELRTSTDIVKSSEEVAAAAEELSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIEEINRSSNEIMGALNQISSGAQHMAKSVETGITSLTQIEQGARLGKERAESSLKACEK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLTGIEENKTTVDEMILAITESTKAATENLNEMANIERISRQIDKIVDGISNVSIQTAML
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AVNGAVEAARAGEYGKGFAVVSTDIQNLANDAAENAEQIKDQVKNIQEQINIVRKDLADI
HHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSTVMEEAQKAALTIKQLDNVRSRMSDVVLGSKRISESAEGIERSIADARAGMQQIATAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EESSHATGEAATAARQQSSSTSELASAIENIAAVADELQSI
HHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALKKHITTSASSSFSPSNHSTSANAPKKEADDLRRQARTLARKQQAAERVASATAELLA
CCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLEESSSAMTQLRSSMEQIAVGAEESSSATKQSETAVSQMNNFINEQATYATQSKQILTK
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQDIVDVANKINEMVSNVQTSSERQNDSVKRMIELSEQAAKINDAVKQVIHIADQTNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ALNAAIEAGRAGKHGKGFAVVADTVRTLAEKAEKNAANIESLIKDISNGAEMVSNGVKSS
EHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCH
SQKAESEVQKGHVVNKQLTLIRNEMVDLVKDSEVLLKAADEMSSAAVIALKGSESVSQAA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
QEQSAACEESLKSLDQQQIALDGAVTAAQSLDELTDELRTSTDIVKSSEEVAAAAEELSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIEEINRSSNEIMGALNQISSGAQHMAKSVETGITSLTQIEQGARLGKERAESSLKACEK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLTGIEENKTTVDEMILAITESTKAATENLNEMANIERISRQIDKIVDGISNVSIQTAML
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AVNGAVEAARAGEYGKGFAVVSTDIQNLANDAAENAEQIKDQVKNIQEQINIVRKDLADI
HHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSTVMEEAQKAALTIKQLDNVRSRMSDVVLGSKRISESAEGIERSIADARAGMQQIATAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EESSHATGEAATAARQQSSSTSELASAIENIAAVADELQSI
HHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]