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The map label for this gene is ompR [H]

Identifier: 147673571

GI number: 147673571

Start: 2442317

End: 2443039

Strand: Reverse

Name: ompR [H]

Synonym: VC0395_A2286

Alternate gene names: 147673571

Gene position: 2443039-2442317 (Counterclockwise)

Preceding gene: 147675721

Following gene: 147673138

Centisome position: 80.79

GC content: 51.18

Gene sequence:

>723_bases
ATGGTGGAAAATCATAAAGTTTTAGTGGTAGATGATGATGCGCGCTTGCGTGCGCTGCTTGAGCGTTACCTGTCCGAGCA
GGGTTTTCAAGTCCGCAGCGTGGCTAACGGCGAGCAGATGGATCGTCTGCTGACGCGCGAAAACTTCCATTTGATGGTGC
TGGATTTGATGTTGCCGGGTGAAGATGGCTTGTCTATCTGTCGACGTTTGCGCAATTCCAACAATATGATCCCGATTCTG
ATGCTCACTGCCAAAGGCGATGAGATTGACCGCATTGTCGGCCTAGAAGTTGGTGCCGATGATTACCTGCCTAAGCCATT
TAACCCACGTGAGTTGCTGGCGCGTATCAAAGCGGTATTGCGCCGCCAAGTGGTTGAAGCGCCGGGAGCGCCCAGTGCAG
AAGAGACCATCATTGAATTTGGTGAGTTTCGCTTAAATCTTGGTACGCGAGAAATGTTCCGTGGTGAAGAGGCGATGCCA
CTCACTTCTGGTGAATTTGCTGTGTTGAAAGCACTCGTGACCAATGCCCGTGAACCGCTTTCGCGCGATAAACTGATGAA
CATGGCGCGTGGCCGTGAATATTCAGCGATGGAGCGTTCGATTGACGTACAGATTTCTCGTCTGCGTCGTATGCTCGAAG
TTGACCCTAGCAAACCGCGCTATATTCAAACCGTATGGGGACTCGGTTACGTGTTTGTTCCTGATGGTAAAGCCGCCAAC
TAA

Upstream 100 bases:

>100_bases
AGACATAAAGATTAACAATTCTTTGCTCCCGGTGAGCGGTAACGATGTTACATTTTACTCGCCCGAAGAGTAGGGGATTG
AACAACAGTTAGGTGGGATC

Downstream 100 bases:

>100_bases
CTTCTTTTAGGCACGCCGGGCAAGGGCGTCCTCGCTCCGCGCGTGCCCTTGCTACATTTAGGTGCCTTATGCGAATTCGC
AGTTCATTTACCCAATCGAT

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MVENHKVLVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDLMLPGEDGLSICRRLRNSNNMIPIL
MLTAKGDEIDRIVGLEVGADDYLPKPFNPRELLARIKAVLRRQVVEAPGAPSAEETIIEFGEFRLNLGTREMFRGEEAMP
LTSGEFAVLKALVTNAREPLSRDKLMNMARGREYSAMERSIDVQISRLRRMLEVDPSKPRYIQTVWGLGYVFVPDGKAAN

Sequences:

>Translated_240_residues
MVENHKVLVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDLMLPGEDGLSICRRLRNSNNMIPIL
MLTAKGDEIDRIVGLEVGADDYLPKPFNPRELLARIKAVLRRQVVEAPGAPSAEETIIEFGEFRLNLGTREMFRGEEAMP
LTSGEFAVLKALVTNAREPLSRDKLMNMARGREYSAMERSIDVQISRLRRMLEVDPSKPRYIQTVWGLGYVFVPDGKAAN
>Mature_240_residues
MVENHKVLVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDLMLPGEDGLSICRRLRNSNNMIPIL
MLTAKGDEIDRIVGLEVGADDYLPKPFNPRELLARIKAVLRRQVVEAPGAPSAEETIIEFGEFRLNLGTREMFRGEEAMP
LTSGEFAVLKALVTNAREPLSRDKLMNMARGREYSAMERSIDVQISRLRRMLEVDPSKPRYIQTVWGLGYVFVPDGKAAN

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=239, Percent_Identity=82.8451882845188, Blast_Score=413, Evalue=1e-117,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.9912663755458, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=37.0833333333333, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=33.7606837606838, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=34.9137931034483, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.3390557939914, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=38.7234042553192, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=36.0869565217391, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=33.8983050847458, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=35.4978354978355, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=34.3612334801762, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=32.7510917030568, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=33.4801762114537, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=32.520325203252, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=123, Percent_Identity=26.8292682926829, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27258; Mature: 27258

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVENHKVLVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDLMLPG
CCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCEEEEEEEECCC
EDGLSICRRLRNSNNMIPILMLTAKGDEIDRIVGLEVGADDYLPKPFNPRELLARIKAVL
CHHHHHHHHHHCCCCEEEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRQVVEAPGAPSAEETIIEFGEFRLNLGTREMFRGEEAMPLTSGEFAVLKALVTNAREPL
HHHHHHCCCCCCHHHHHHHHHHHEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCH
SRDKLMNMARGREYSAMERSIDVQISRLRRMLEVDPSKPRYIQTVWGLGYVFVPDGKAAN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MVENHKVLVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDLMLPG
CCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCEEEEEEEECCC
EDGLSICRRLRNSNNMIPILMLTAKGDEIDRIVGLEVGADDYLPKPFNPRELLARIKAVL
CHHHHHHHHHHCCCCEEEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRQVVEAPGAPSAEETIIEFGEFRLNLGTREMFRGEEAMPLTSGEFAVLKALVTNAREPL
HHHHHHCCCCCCHHHHHHHHHHHEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCH
SRDKLMNMARGREYSAMERSIDVQISRLRRMLEVDPSKPRYIQTVWGLGYVFVPDGKAAN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]