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The map label for this gene is cobA [H]

Identifier: 147673401

GI number: 147673401

Start: 599470

End: 600075

Strand: Reverse

Name: cobA [H]

Synonym: VC0395_A0558

Alternate gene names: 147673401

Gene position: 600075-599470 (Counterclockwise)

Preceding gene: 147675389

Following gene: 147673338

Centisome position: 19.84

GC content: 49.34

Gene sequence:

>606_bases
ATGTCCGGCGATGAAATCAAACAAGAGCGTCACAAAGCTCGTCAACAAAAAGTCAAAGAGCAAGTGGATGCCAAAATTGC
CGCCGCTCAAGAAGAAAAAGGGTTGCTGCTGATTATTACTGGCAATGGTAAAGGAAAATCGACCTCAGGTTTTGGCACCA
TTGCGCGCGCGGTAGGTCACGGTAAACAGTGTGCGGTGGCTCAGTTTATCAAAGGCACTTGGGAGAATGGTGAGCGTAAT
CTTTTAGAAAAGCTCGGCGTTGAATTTCAAGTCATGTCGACTGGCTTTACTTGGGAAACCCAGAACCGCGACAGCGATAC
CGCAGCGGCACAAGAAGTATGGCAACACTGCAAACGCATGTTGCAGGATGAATCGCTGGATGTGGTGCTGTTTGATGAGC
TCACTTACATGGTGAGCTACGGTTACATCGAGTTGGATGAAGTGGTCGAAGCACTCAATCAGCGTCCGAAAATGCAATCG
GTGATCATCACGGGGCGCGGCGCACACCGCACTTTGATTGAGATGGCCGATACGGTTTCTGAAGTGAAAAACATCAAGCA
CGCTTTCGAATCCGGCGTGAAAGCCCTTAAAGGGGTCGATTGGTAA

Upstream 100 bases:

>100_bases
GAGTACCTTCTGCATCTTATATCCCTATTTTTGTTTGGTGTTTGCCACTGACGAGTTGGGCTATCATAGCGACAAGTTTC
AGATTGAAAAAGGATTTGCC

Downstream 100 bases:

>100_bases
AACACTTAAAAAAATCAATAAGAAAGGGCTGATATTCAGCCCTTTTTAGTTTCATTAGCGATGCATAACCATCAGTTAAA
TAGACCTTTTAGCAACCCAT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGHGKQCAVAQFIKGTWENGERN
LLEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRMLQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQS
VIITGRGAHRTLIEMADTVSEVKNIKHAFESGVKALKGVDW

Sequences:

>Translated_201_residues
MSGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGHGKQCAVAQFIKGTWENGERN
LLEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRMLQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQS
VIITGRGAHRTLIEMADTVSEVKNIKHAFESGVKALKGVDW
>Mature_200_residues
SGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGHGKQCAVAQFIKGTWENGERNL
LEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRMLQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQSV
IITGRGAHRTLIEMADTVSEVKNIKHAFESGVKALKGVDW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=66.8367346938776, Blast_Score=293, Evalue=4e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22413; Mature: 22282

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCC
GKQCAVAQFIKGTWENGERNLLEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRM
CCHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHH
LQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQSVIITGRGAHRTLIEMADTVS
HCCCCCCEEEHHHHHHHHHCCCEEHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHH
EVKNIKHAFESGVKALKGVDW
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCC
GKQCAVAQFIKGTWENGERNLLEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRM
CCHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHH
LQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQSVIITGRGAHRTLIEMADTVS
HCCCCCCEEEHHHHHHHHHCCCEEHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHH
EVKNIKHAFESGVKALKGVDW
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]