Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 147673103

GI number: 147673103

Start: 2348144

End: 2349241

Strand: Reverse

Name: trpS [H]

Synonym: VC0395_A2200

Alternate gene names: 147673103

Gene position: 2349241-2348144 (Counterclockwise)

Preceding gene: 147673858

Following gene: 147673998

Centisome position: 77.68

GC content: 48.82

Gene sequence:

>1098_bases
TTGAACCGCGCCGATTCCGTGCGCGGTTTTTGTCCCTTTGTTTTGTGTAATTTCAATTTCAGTCACAAGGAAATCAAACC
CATGAGCAAACCCATTGTATTGAGTGGTGTTCAACCGTCAGGTGAACTAAGTATCGGTAACTACTTGGGTGCTCTACGTC
AATGGCAACAGATGCAAGATGATTATGACTGCCAGTACTGTGTTGTGGATTTGCATGCAATTACGGTTCGCCAAGATCCG
CAAGCACTGCATGAAGCGACATTAGATGCTTTGGCTATTTGTCTCGCCGTTGGCGTTGATCCGAAAAAGAGCACGCTATT
TGTTCAGTCACACGTACCTGAGCATGCTCAACTCGGTTGGGTTTTGAACTGCTACACCCAGATGGGTGAGCTGAGCCGCA
TGACTCAATTCAAAGACAAATCAGCACGTTACGCCAACGATGTGAATGCTGGTCTGTTTGGTTATCCGGTACTGATGGCG
GCAGATATTCTGCTGTATGGCGCGCACCAAGTGCCAGTGGGCAGCGATCAGAAACAACATCTGGAATTGGCACGCGATAT
CGCGACCCGTTTCAACAATATCTACAGCCCAGAACAGCCGATTTTTACCATTCCTGAGCCTTACATCCCAACCGTGAATG
CGCGGGTAATGAGTCTGCAAGATGCGACTAAGAAAATGTCCAAATCAGACGATAACCGCAAAAACGTGATCACCTTGTTG
GAAGATCCGAAATCGATCATCAAGAAGATCAATAAGGCGCAGACCGATGCGGAAACCCCACCGCGTATCGCTTACGATGT
TGAAAACAAAGCAGGCATCGCGAACCTGATGGGACTCTATTCTGCCGCGACAGGTAAAACCTTCGCCGAAATCGAAGCTC
AGTACGCAGGCGTTGAAATGTACGGCCCATTTAAGAAAGATGTGGGTGAGGCTGTGGTGGCCATGCTTGAACCCGTGCAA
GCAGAATACCAACGCATCCGTAACGATCGCGAATACCTGAACAGTGTAATGCGTGATGGCGCAGAAAAAGCCTCGGCAAA
AGCGCTGCAAACGCTGAAAAAAGTCTATGCGGCGGTTGGTTTTGTGGCGCGTCCTTAA

Upstream 100 bases:

>100_bases
TTCGTCTCCGATGATATTGGCACGCTGCTTGAAGTGGTGCTCGTTTCGGCGTAAAAGTTGCCGTTCGCACTAGTAAAATA
CTCGTTAATGAGTACACTGC

Downstream 100 bases:

>100_bases
GCCAAAGCGAGCACAATCAAGTCACAGTGAATAAAGCTAGGGTTTCCTAGCTTTATTTTTTGCACGCGAGATAGGTTTGC
ACAGAGCGAAAGTGTGTGAG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNRADSVRGFCPFVLCNFNFSHKEIKPMSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDP
QALHEATLDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWVLNCYTQMGELSRMTQFKDKSARYANDVNAGLFGYPVLMA
ADILLYGAHQVPVGSDQKQHLELARDIATRFNNIYSPEQPIFTIPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLL
EDPKSIIKKINKAQTDAETPPRIAYDVENKAGIANLMGLYSAATGKTFAEIEAQYAGVEMYGPFKKDVGEAVVAMLEPVQ
AEYQRIRNDREYLNSVMRDGAEKASAKALQTLKKVYAAVGFVARP

Sequences:

>Translated_365_residues
MNRADSVRGFCPFVLCNFNFSHKEIKPMSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDP
QALHEATLDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWVLNCYTQMGELSRMTQFKDKSARYANDVNAGLFGYPVLMA
ADILLYGAHQVPVGSDQKQHLELARDIATRFNNIYSPEQPIFTIPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLL
EDPKSIIKKINKAQTDAETPPRIAYDVENKAGIANLMGLYSAATGKTFAEIEAQYAGVEMYGPFKKDVGEAVVAMLEPVQ
AEYQRIRNDREYLNSVMRDGAEKASAKALQTLKKVYAAVGFVARP
>Mature_365_residues
MNRADSVRGFCPFVLCNFNFSHKEIKPMSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAITVRQDP
QALHEATLDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWVLNCYTQMGELSRMTQFKDKSARYANDVNAGLFGYPVLMA
ADILLYGAHQVPVGSDQKQHLELARDIATRFNNIYSPEQPIFTIPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLL
EDPKSIIKKINKAQTDAETPPRIAYDVENKAGIANLMGLYSAATGKTFAEIEAQYAGVEMYGPFKKDVGEAVVAMLEPVQ
AEYQRIRNDREYLNSVMRDGAEKASAKALQTLKKVYAAVGFVARP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=335, Percent_Identity=40, Blast_Score=264, Evalue=1e-70,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=49.7206703910614, Blast_Score=184, Evalue=7e-47,
Organism=Escherichia coli, GI1789786, Length=338, Percent_Identity=67.1597633136095, Blast_Score=478, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI71982800, Length=359, Percent_Identity=34.2618384401114, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71982793, Length=338, Percent_Identity=35.207100591716, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320474, Length=351, Percent_Identity=39.3162393162393, Blast_Score=230, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24666151, Length=347, Percent_Identity=40.9221902017291, Blast_Score=246, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 40573; Mature: 40573

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRADSVRGFCPFVLCNFNFSHKEIKPMSKPIVLSGVQPSGELSIGNYLGALRQWQQMQD
CCCCCCCCCCCCEEEECCCCCHHHHCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCC
DYDCQYCVVDLHAITVRQDPQALHEATLDALAICLAVGVDPKKSTLFVQSHVPEHAQLGW
CCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
VLNCYTQMGELSRMTQFKDKSARYANDVNAGLFGYPVLMAADILLYGAHQVPVGSDQKQH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LELARDIATRFNNIYSPEQPIFTIPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLL
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
EDPKSIIKKINKAQTDAETPPRIAYDVENKAGIANLMGLYSAATGKTFAEIEAQYAGVEM
CCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEE
YGPFKKDVGEAVVAMLEPVQAEYQRIRNDREYLNSVMRDGAEKASAKALQTLKKVYAAVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FVARP
HHCCC
>Mature Secondary Structure
MNRADSVRGFCPFVLCNFNFSHKEIKPMSKPIVLSGVQPSGELSIGNYLGALRQWQQMQD
CCCCCCCCCCCCEEEECCCCCHHHHCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCC
DYDCQYCVVDLHAITVRQDPQALHEATLDALAICLAVGVDPKKSTLFVQSHVPEHAQLGW
CCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
VLNCYTQMGELSRMTQFKDKSARYANDVNAGLFGYPVLMAADILLYGAHQVPVGSDQKQH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LELARDIATRFNNIYSPEQPIFTIPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLL
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
EDPKSIIKKINKAQTDAETPPRIAYDVENKAGIANLMGLYSAATGKTFAEIEAQYAGVEM
CCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEE
YGPFKKDVGEAVVAMLEPVQAEYQRIRNDREYLNSVMRDGAEKASAKALQTLKKVYAAVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FVARP
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]