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The map label for this gene is dacC [H]

Identifier: 146343356

GI number: 146343356

Start: 6832354

End: 6833784

Strand: Direct

Name: dacC [H]

Synonym: BRADO6583

Alternate gene names: 146343356

Gene position: 6832354-6833784 (Clockwise)

Preceding gene: 146343355

Following gene: 146343357

Centisome position: 91.63

GC content: 68.48

Gene sequence:

>1431_bases
GTGCAGACGCTTCGCCTGTTGTTCCGCTATTCCCCGCTGAAGATCATCGCTGTTGCTGCCGCGCTAATGCTCGCGCCGCG
TATGGCCCATGCCGAGGCGCTTCTGCTCGTCGAGGCCGACACCGGCAAGGTGCTCGAGGCGCAGAACGCGACCTATCCCT
GGTACCCCGCCTCCGTCACCAAGCTGATGACGGCCTATGTCACGCTGAAGGCGGTGAAGGACGGCAAGGCCTCGCTCGAC
ACGCTGCTGACGGTGTCGCCGACCGCGGCGTCGCAATCGCCCTCGAAGATGGGCTACCGGCCGGGCACACAGGTCACCGT
CGACAACGCACTGAAGATGATGCTGGTGAAGTCGGCCAACGACATGGCTGTCGTGCTGGCGGAAGGCATCGGCGGCTCGA
TCGACGGCTTCTCGATCATGATGAACGAGACCGCGCAGCGGCTCGGCATGACCCAGACGAGCTACGTCAATCCGAACGGC
CTGCCCGCCGACGGCCAGATCACCTCGGCCCGCGACCTCGCGATCCTGGCGCGCGCCATCATTCGCGACCTGCCGGAATA
CGAATATTTCGTCCACATCCCCTCGATCCGCTACGGCCGCCGGGTGGTGCAGAACTTCAACCGGCTGATCGGGCGCTATC
CCGGCGCCGACGGCTTCAAGACCGGCTTCATCTGCGCCTCCGGCTACAATCTGGTGGCGTCCGCCACCCGCAACGGCAAG
CGCCTGATCGCGGTCGTGCTTGGCGCCTCCTCAGGCCAGATGCGCGCGGTGCGCGCGATCCAGATGCTCGATCGCGGCTT
CAACACCAATCAACTCAGCTGGCTCAAGGCGCCGCTCGGCAATGTCGAGCAGCTGGTGCCGGTTGACGCCACCCCGCCGA
ACCTGCGCGATGACATGTGCAGCGGCCGCCGGCACCGGCCCGCCAGCGATGACGACGGCGAGGAGGCGAGCAACGAGGGC
GAGACGACCACCGGCGGGACGCTGCTCGCCGGGCTGCAGGCGCCGGCGCTGAAGCCGTCGGAGATCCTGGCAGCAGCGCC
TGCGCCGTCCGAGCCCGTGCTGGTCTATACCGGCCCGACCCGTACCGGTCCTGCGCTGATCGCCGCCGTCGCGGCTGACG
CCGATGCCCAGACCCCGCCCAAGCACCGCGGCAAGAAGGCGCATGCCGCCGGGAAGACCGACGCCAAGCCGGCGACGCAC
ACGGCGGCCAAGTCTGATGGCAAGACCGGCAGTGAGGCCAAGCCGGCCGGCAAGCCTGATTCGAAGACCGCCGACGCCAA
GTCGGCCACGGCACGCCACGTCGCCGCCAAGCACGACACGGGCGCGAAATCTGCGGACAAGCCGGCCTCCGACACCGCGG
CCAAGCCGGCCAAGCCCAAGGCAGCCGCCAGGCCGAAGACCGACGGCAAGCCGGCGCCGAAGGACGGCTGA

Upstream 100 bases:

>100_bases
CTGCCGCAACCAAAGCGGCGCCGGACACGCTTGAAACCCGAAAGCCCGTTTGCCCACCTCGCTCGCGCGAGGCGGGTTCT
CAAAGGACCGGACCAGACCA

Downstream 100 bases:

>100_bases
TCGCGGAGCGAACCCGCGGGCGCCCCCAAGCGCATTCACCTTCCTCCTTCGACGAGGTCCCGGCCGCTTGCCTTGGCCGG
CCGGAGGTGAGATTTTGGCC

Product: putative D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MQTLRLLFRYSPLKIIAVAAALMLAPRMAHAEALLLVEADTGKVLEAQNATYPWYPASVTKLMTAYVTLKAVKDGKASLD
TLLTVSPTAASQSPSKMGYRPGTQVTVDNALKMMLVKSANDMAVVLAEGIGGSIDGFSIMMNETAQRLGMTQTSYVNPNG
LPADGQITSARDLAILARAIIRDLPEYEYFVHIPSIRYGRRVVQNFNRLIGRYPGADGFKTGFICASGYNLVASATRNGK
RLIAVVLGASSGQMRAVRAIQMLDRGFNTNQLSWLKAPLGNVEQLVPVDATPPNLRDDMCSGRRHRPASDDDGEEASNEG
ETTTGGTLLAGLQAPALKPSEILAAAPAPSEPVLVYTGPTRTGPALIAAVAADADAQTPPKHRGKKAHAAGKTDAKPATH
TAAKSDGKTGSEAKPAGKPDSKTADAKSATARHVAAKHDTGAKSADKPASDTAAKPAKPKAAARPKTDGKPAPKDG

Sequences:

>Translated_476_residues
MQTLRLLFRYSPLKIIAVAAALMLAPRMAHAEALLLVEADTGKVLEAQNATYPWYPASVTKLMTAYVTLKAVKDGKASLD
TLLTVSPTAASQSPSKMGYRPGTQVTVDNALKMMLVKSANDMAVVLAEGIGGSIDGFSIMMNETAQRLGMTQTSYVNPNG
LPADGQITSARDLAILARAIIRDLPEYEYFVHIPSIRYGRRVVQNFNRLIGRYPGADGFKTGFICASGYNLVASATRNGK
RLIAVVLGASSGQMRAVRAIQMLDRGFNTNQLSWLKAPLGNVEQLVPVDATPPNLRDDMCSGRRHRPASDDDGEEASNEG
ETTTGGTLLAGLQAPALKPSEILAAAPAPSEPVLVYTGPTRTGPALIAAVAADADAQTPPKHRGKKAHAAGKTDAKPATH
TAAKSDGKTGSEAKPAGKPDSKTADAKSATARHVAAKHDTGAKSADKPASDTAAKPAKPKAAARPKTDGKPAPKDG
>Mature_476_residues
MQTLRLLFRYSPLKIIAVAAALMLAPRMAHAEALLLVEADTGKVLEAQNATYPWYPASVTKLMTAYVTLKAVKDGKASLD
TLLTVSPTAASQSPSKMGYRPGTQVTVDNALKMMLVKSANDMAVVLAEGIGGSIDGFSIMMNETAQRLGMTQTSYVNPNG
LPADGQITSARDLAILARAIIRDLPEYEYFVHIPSIRYGRRVVQNFNRLIGRYPGADGFKTGFICASGYNLVASATRNGK
RLIAVVLGASSGQMRAVRAIQMLDRGFNTNQLSWLKAPLGNVEQLVPVDATPPNLRDDMCSGRRHRPASDDDGEEASNEG
ETTTGGTLLAGLQAPALKPSEILAAAPAPSEPVLVYTGPTRTGPALIAAVAADADAQTPPKHRGKKAHAAGKTDAKPATH
TAAKSDGKTGSEAKPAGKPDSKTADAKSATARHVAAKHDTGAKSADKPASDTAAKPAKPKAAARPKTDGKPAPKDG

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=270, Percent_Identity=38.5185185185185, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786851, Length=244, Percent_Identity=38.1147540983607, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87082022, Length=253, Percent_Identity=36.7588932806324, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87082054, Length=242, Percent_Identity=29.7520661157025, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 49877; Mature: 49877

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLRLLFRYSPLKIIAVAAALMLAPRMAHAEALLLVEADTGKVLEAQNATYPWYPASVT
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCCCCCCCCHHHH
KLMTAYVTLKAVKDGKASLDTLLTVSPTAASQSPSKMGYRPGTQVTVDNALKMMLVKSAN
HHHHHHHHEEHHCCCCCCCCEEEEECCCCCCCCCHHCCCCCCCEEEHHHHHHHHHHCCCC
DMAVVLAEGIGGSIDGFSIMMNETAQRLGMTQTSYVNPNGLPADGQITSARDLAILARAI
CEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IRDLPEYEYFVHIPSIRYGRRVVQNFNRLIGRYPGADGFKTGFICASGYNLVASATRNGK
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEECCCCCC
RLIAVVLGASSGQMRAVRAIQMLDRGFNTNQLSWLKAPLGNVEQLVPVDATPPNLRDDMC
EEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHEEECCCCCCCCHHHHH
SGRRHRPASDDDGEEASNEGETTTGGTLLAGLQAPALKPSEILAAAPAPSEPVLVYTGPT
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHEEECCCCCCCEEEEECCC
RTGPALIAAVAADADAQTPPKHRGKKAHAAGKTDAKPATHTAAKSDGKTGSEAKPAGKPD
CCCCHHEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCC
SKTADAKSATARHVAAKHDTGAKSADKPASDTAAKPAKPKAAARPKTDGKPAPKDG
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTLRLLFRYSPLKIIAVAAALMLAPRMAHAEALLLVEADTGKVLEAQNATYPWYPASVT
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCCCCCCCCHHHH
KLMTAYVTLKAVKDGKASLDTLLTVSPTAASQSPSKMGYRPGTQVTVDNALKMMLVKSAN
HHHHHHHHEEHHCCCCCCCCEEEEECCCCCCCCCHHCCCCCCCEEEHHHHHHHHHHCCCC
DMAVVLAEGIGGSIDGFSIMMNETAQRLGMTQTSYVNPNGLPADGQITSARDLAILARAI
CEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IRDLPEYEYFVHIPSIRYGRRVVQNFNRLIGRYPGADGFKTGFICASGYNLVASATRNGK
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEECCCCCC
RLIAVVLGASSGQMRAVRAIQMLDRGFNTNQLSWLKAPLGNVEQLVPVDATPPNLRDDMC
EEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHEEECCCCCCCCHHHHH
SGRRHRPASDDDGEEASNEGETTTGGTLLAGLQAPALKPSEILAAAPAPSEPVLVYTGPT
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHEEECCCCCCCEEEEECCC
RTGPALIAAVAADADAQTPPKHRGKKAHAAGKTDAKPATHTAAKSDGKTGSEAKPAGKPD
CCCCHHEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCC
SKTADAKSATARHVAAKHDTGAKSADKPASDTAAKPAKPKAAARPKTDGKPAPKDG
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]